-
1.发明授权Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders 有权使用磷虾油治疗心血管，代谢和炎性疾病的危险因素的方法公开(公告)号：US08697138B2
公开(公告)日：2014-04-15
申请号：US12790575
申请日：2010-05-28
申请人： Inge Bruheim , Snorre Tilseth , Jeffery Cohn , Mikko Griinari , Daniele Mancinelli , Nils Hoem , Hogne Vik , Sebastiano Banni
发明人： Inge Bruheim , Snorre Tilseth , Jeffery Cohn , Mikko Griinari , Daniele Mancinelli , Nils Hoem , Hogne Vik , Sebastiano Banni
CPC分类号： A61K35/612 , A61K31/202 , A61K31/215 , A61K31/683
摘要： This invention discloses methods of using krill oil and compositions comprising krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. The present invention also relates to methods of using compositions comprising krill oil to modulate biological processes selected from the group consisting of glucose metabolism, lipid biosynthesis, fatty acid metabolism, cholesterol biosynthesis, and the mitochondrial respiratory chain. The present invention further includes pharmaceutical and/or nutraceutical formulations made from krill oil, methods of making such formulations, and methods of administering them to treat risk factors for metabolic, cardiovascular, and inflammatory disorders.
摘要翻译： 本发明公开了使用磷虾油和包含磷虾油的组合物来治疗代谢，心血管和炎症性疾病的危险因素的方法。 本发明还涉及使用包含磷虾油的组合物调节选自葡萄糖代谢，脂质生物合成，脂肪酸代谢，胆固醇生物合成和线粒体呼吸链的生物过程的方法。 本发明还包括由磷虾油制备的药物和/或营养制剂，制备这些制剂的方法，以及施用它们以治疗代谢，心血管和炎性疾病的危险因素的方法。
-
2.发明申请METHODS OF USING KRILL OIL TO TREAT RISK FACTORS FOR CARDIOVASCULAR, METABOLIC, AND INFLAMMATORY DISORDERS 有权使用KRILL油治疗心血管，代谢和炎症性疾病的风险因子的方法公开(公告)号：US20110104297A1
公开(公告)日：2011-05-05
申请号：US12790575
申请日：2010-05-28
申请人： Inge BRUHEIM , Snorre Tilseth , Jeffery Cohn , Mikko Griinari , Daniele Mancinelli , Nils Hoem , Hogne Vik , Sebastiano Banni
发明人： Inge BRUHEIM , Snorre Tilseth , Jeffery Cohn , Mikko Griinari , Daniele Mancinelli , Nils Hoem , Hogne Vik , Sebastiano Banni
CPC分类号： A61K35/612 , A61K31/202 , A61K31/215 , A61K31/683
摘要： This invention discloses methods of using krill oil and compositions comprising krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. The present invention also relates to methods of using compositions comprising krill oil to modulate biological processes selected from the group consisting of glucose metabolism, lipid biosynthesis, fatty acid metabolism, cholesterol biosynthesis, and the mitochondrial respiratory chain. The present invention further includes pharmaceutical and/or nutraceutical formulations made from krill oil, methods of making such formulations, and methods of administering them to treat risk factors for metabolic, cardiovascular, and inflammatory disorders.
摘要翻译： 本发明公开了使用磷虾油和包含磷虾油的组合物来治疗代谢，心血管和炎症性疾病的危险因素的方法。 本发明还涉及使用包含磷虾油的组合物调节选自葡萄糖代谢，脂质生物合成，脂肪酸代谢，胆固醇生物合成和线粒体呼吸链的生物过程的方法。 本发明还包括由磷虾油制备的药物和/或营养制剂，制备这些制剂的方法，以及施用它们以治疗代谢，心血管和炎性疾病的危险因素的方法。
-
公开(公告)号：US09034388B2
公开(公告)日：2015-05-19
申请号：US12057775
申请日：2008-03-28
申请人： Inge Bruheim , Mikko Griinari , Snorre Tilseth , Sebastiano Banni , Jeffrey Stuart Cohn , Daniele Mancinelli
发明人： Inge Bruheim , Mikko Griinari , Snorre Tilseth , Sebastiano Banni , Jeffrey Stuart Cohn , Daniele Mancinelli
IPC分类号： A61K9/48 , A61K31/23 , A61K31/122 , A61K31/202 , A61K31/683 , A61K31/685 , C11B3/00 , A61K45/06
CPC分类号： A61K35/612 , A23L33/115 , A23V2002/00 , A61K9/0053 , A61K9/48 , A61K9/4825 , A61K9/4858 , A61K31/122 , A61K31/20 , A61K31/202 , A61K31/215 , A61K31/23 , A61K31/235 , A61K31/575 , A61K31/683 , A61K31/685 , A61K45/06 , C11B3/006 , A61K2300/00
摘要： This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO2 or CO2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.
摘要翻译： 本发明公开了新的磷虾油组合物，其特征在于含有大量的磷脂，虾青素酯和/或ω-3含量。 磷虾油在两阶段过程中使用超临界流体萃取从磷虾粉中获得。 阶段1通过用纯超临界CO 2或CO 2加上约5％的共溶剂萃取来除去中性脂质。 阶段2通过使用超临界CO2与约20％乙醇组合提取实际的磷虾油。 将所获得的磷虾油材料与市售的磷虾油进行比较，发现在抗炎，抗氧化作用，改善胰岛素抵抗和改善血脂特征等多个领域中具有更高的生物有效性。
-
公开(公告)号：US20080274203A1
公开(公告)日：2008-11-06
申请号：US12057775
申请日：2008-03-28
申请人： Inge Bruheim , Mikko Griinari , Snorre Tilseth , Sebastiano Banni , Jeffrey Stuart Cohn , Daniele Mancinelli
发明人： Inge Bruheim , Mikko Griinari , Snorre Tilseth , Sebastiano Banni , Jeffrey Stuart Cohn , Daniele Mancinelli
IPC分类号： A61K35/56 , A61K31/661 , A61K31/685 , A61P3/02 , A23D9/00 , A61K31/66
CPC分类号： A61K35/612 , A23L33/115 , A23V2002/00 , A61K9/0053 , A61K9/48 , A61K9/4825 , A61K9/4858 , A61K31/122 , A61K31/20 , A61K31/202 , A61K31/215 , A61K31/23 , A61K31/235 , A61K31/575 , A61K31/683 , A61K31/685 , A61K45/06 , C11B3/006 , A61K2300/00
摘要： This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO2 or CO2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.
摘要翻译： 本发明公开了新的磷虾油组合物，其特征在于含有大量的磷脂，虾青素酯和/或ω-3含量。 磷虾油在两阶段过程中使用超临界流体萃取从磷虾粉中获得。 阶段1通过用纯超临界CO 2 CO 2或CO 2加上约5％的助溶剂萃取来除去中性脂质。 阶段2通过使用超临界CO 2与大约20％的乙醇组合提取实际的磷虾油。 将所获得的磷虾油材料与市售的磷虾油进行比较，发现在抗炎，抗氧化作用，改善胰岛素抵抗和改善血脂特征等多个领域中具有更高的生物有效性。
-
公开(公告)号：US20080044487A1
公开(公告)日：2008-02-21
申请号：US11800229
申请日：2007-05-04
IPC分类号： A61K35/12 , A61K31/685 , A61P29/00 , C07F9/02
CPC分类号： A61K31/685 , C07F9/10
摘要： Novel marine lipid compositions comprising triglycerides and omega-3 rich phospholipids are described. The compositions are characterized by providing highly bioavailable omega-3, increased tissue incorporation of omega-3 and reduced concentration of pro-inflammatory cytokines.
摘要翻译： 描述了包含甘油三酯和富含ω-3的磷脂的新型海洋脂质组合物。 组合物的特征在于提供高度生物可利用的ω-3，增加的ω-3的组织结合和促炎细胞因子的浓度降低。
-
公开(公告)号：US10117882B2
公开(公告)日：2018-11-06
申请号：US12849950
申请日：2010-08-04
IPC分类号： A61K31/685 , C07F9/10
摘要： Novel marine lipid compositions comprising triglycerides and omega-3 rich phospholipids are described. The compositions are characterized by providing highly bioavailable omega-3, increased tissue incorporation of omega-3 and reduced concentration of pro-inflammatory cytokines.
-
公开(公告)号：US20100316680A1
公开(公告)日：2010-12-16
申请号：US12849950
申请日：2010-08-04
IPC分类号： A61K31/685 , C07F9/10 , A61K31/683 , A61K9/00 , A61P3/02 , A61P29/00
CPC分类号： A61K31/685 , C07F9/10
摘要： Novel marine lipid compositions comprising triglycerides and omega-3 rich phospholipids are described. The compositions are characterized by providing highly bioavailable omega-3, increased tissue incorporation of omega-3 and reduced concentration of pro-inflammatory cytokines.
摘要翻译： 描述了包含甘油三酯和富含ω-3的磷脂的新型海洋脂质组合物。 组合物的特征在于提供高度生物可利用的ω-3，增加的ω-3的组织结合和促炎细胞因子的浓度降低。
-
-
-
-
-
-
搜索结果
7 条记录 (耗时 0.035 秒)
