公开(公告)号：US12103915B2

公开(公告)日：2024-10-01

申请号：US18529689

申请日：2023-12-05

Applicant: Insilico Medicine IP Limited

Inventor： Xiao Ding ,  Jinxin Liu ,  Feng Ren ,  Jianfei Wan ,  Wei Zhu

IPC: C07D231/56 ,  A61P35/00 ,  C07D209/44 ,  C07D215/14 ,  C07D401/04 ,  C07D403/08 ,  C07D471/04 ,  C07D487/04

CPC classification number: C07D231/56 ,  A61P35/00 ,  C07D209/44 ,  C07D215/14 ,  C07D401/04 ,  C07D403/08 ,  C07D471/04 ,  C07D487/04

Abstract: The disclosure provides for compounds and methods for modulating or inhibiting TEAD. Further provided herein are pharmaceutical compositions comprising the TEAD inhibitors and methods of treatment using the TEAD inhibitors or the pharmaceutical compositions.