Electrical trapping and stretching of charged biomolecules by single electrode gating structure

    公开(公告)号:US10344324B2

    公开(公告)日:2019-07-09

    申请号:US14225677

    申请日:2014-03-26

    摘要: A technique is provided for controlling biomolecules in a nanodevice. A membrane has two reservoirs at opposing ends of the membrane. A nanochannel is formed in the membrane connecting the two reservoirs. A gate electrode is formed on the membrane such that the gate electrode extends laterally in a region of the nanochannel. A biomolecule is trapped in the nanochannel by applying a first voltage to the gate electrode. In response to trapping the biomolecule, the biomolecule is stretched in the nanochannel by applying a second voltage to the gate electrode. The biomolecule is stretched based on changing from the first voltage to the second voltage applied to the gate electrode.

    NANO-RING GATE ELECTRODE NANOCHANNELS
    2.
    发明申请
    NANO-RING GATE ELECTRODE NANOCHANNELS 有权
    纳米门电极纳米通道

    公开(公告)号:US20150276665A1

    公开(公告)日:2015-10-01

    申请号:US14695390

    申请日:2015-04-24

    IPC分类号: G01N27/414 C12Q1/68

    摘要: A technique includes providing a nanodevice. A gate electrode structure has nanochannels with a first end connected to a first common trench and a second end connected to a second common trench. A gate electrode extends laterally as a continuous line on the gate electrode structure and is formed in each of the nanochannels. The gate electrode forms a separate nano-ring electrode around a partial circumference inside each of the nanochannels. The gate electrode is parallel to the first and second common trenches and is perpendicular to the nanochannels.

    摘要翻译: 一种技术包括提供一种纳米设备。 栅极电极结构具有纳米通道,其第一端连接到第一公共沟槽,第二端连接到第二公共沟槽。 栅极电极在栅电极结构上作为连续线横向延伸并形成在每个纳米通道中。 栅电极在每个纳米通道内围绕部分圆周形成单独的纳米环电极。 栅电极平行于第一和第二公共沟槽并且垂直于纳米通道。

    NANO-RING GATE ELECTRODE NANOCHANNELS

    公开(公告)号:US20150276664A1

    公开(公告)日:2015-10-01

    申请号:US14225694

    申请日:2014-03-26

    摘要: A technique includes providing a nanodevice. A gate electrode structure has nanochannels with a first end connected to a first common trench and a second end connected to a second common trench. A gate electrode extends laterally as a continuous line on the gate electrode structure and is formed in each of the nanochannels. The gate electrode forms a separate nano-ring electrode around a partial circumference inside each of the nanochannels. The gate electrode is parallel to the first and second common trenches and is perpendicular to the nanochannels.

    Nano-ring gate electrode nanochannels
    4.
    发明授权
    Nano-ring gate electrode nanochannels 有权
    纳米环栅电极纳米通道

    公开(公告)号:US09146211B1

    公开(公告)日:2015-09-29

    申请号:US14225694

    申请日:2014-03-26

    摘要: A technique includes providing a nanodevice. A gate electrode structure has nanochannels with a first end connected to a first common trench and a second end connected to a second common trench. A gate electrode extends laterally as a continuous line on the gate electrode structure and is formed in each of the nanochannels. The gate electrode forms a separate nano-ring electrode around a partial circumference inside each of the nanochannels. The gate electrode is parallel to the first and second common trenches and is perpendicular to the nanochannels.

    摘要翻译: 一种技术包括提供一种纳米设备。 栅极电极结构具有纳米通道,其第一端连接到第一公共沟槽,第二端连接到第二公共沟槽。 栅极电极在栅电极结构上作为连续线横向延伸并形成在每个纳米通道中。 栅电极在每个纳米通道内围绕部分圆周形成单独的纳米环电极。 栅电极平行于第一和第二公共沟槽并且垂直于纳米通道。

    Nano-ring gate electrode nanochannels

    公开(公告)号:US09285337B2

    公开(公告)日:2016-03-15

    申请号:US14695390

    申请日:2015-04-24

    摘要: A technique includes providing a nanodevice. A gate electrode structure has nanochannels with a first end connected to a first common trench and a second end connected to a second common trench. A gate electrode extends laterally as a continuous line on the gate electrode structure and is formed in each of the nanochannels. The gate electrode forms a separate nano-ring electrode around a partial circumference inside each of the nanochannels. The gate electrode is parallel to the first and second common trenches and is perpendicular to the nanochannels.

    ELECTRICAL TRAPPING AND STRETCHING OF CHARGED BIOMOLECULES BY SINGLE ELECTRODE GATING STRUCTURE
    6.
    发明申请
    ELECTRICAL TRAPPING AND STRETCHING OF CHARGED BIOMOLECULES BY SINGLE ELECTRODE GATING STRUCTURE 审中-公开
    通过单电极电位结构对电荷生物分子进行电牵引和拉伸

    公开(公告)号:US20150275288A1

    公开(公告)日:2015-10-01

    申请号:US14225677

    申请日:2014-03-26

    IPC分类号: C12Q1/68 G01N27/40 G01N27/447

    摘要: A technique is provided for controlling biomolecules in a nanodevice. A membrane has two reservoirs at opposing ends of the membrane. A nanochannel is formed in the membrane connecting the two reservoirs. A gate electrode is formed on the membrane such that the gate electrode extends laterally in a region of the nanochannel. A biomolecule is trapped in the nanochannel by applying a first voltage to the gate electrode. In response to trapping the biomolecule, the biomolecule is stretched in the nanochannel by applying a second voltage to the gate electrode. The biomolecule is stretched based on changing from the first voltage to the second voltage applied to the gate electrode.

    摘要翻译: 提供了一种用于控制纳米设备中生物分子的技术。 膜在膜的相对端具有两个储存器。 在连接两个储存器的膜中形成纳米通道。 栅电极形成在膜上,使得栅电极在纳米通道的区域中横向延伸。 生物分子通过向栅电极施加第一电压而被捕获在纳米通道中。 响应于捕获生物分子,通过向栅电极施加第二电压,在纳米通道中拉伸生物分子。 基于从施加到栅电极的第一电压到第二电压的变化,生物分子被拉伸。