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    Method and composition for treating gastro-esophageal disorders
    2.
    发明授权
    Method and composition for treating gastro-esophageal disorders 有权

    公开(公告)号：US11090329B2

    公开(公告)日：2021-08-17

    申请号：US15583791

    申请日：2017-05-01

    申请人： Ismail Gurol ,  Robert Burns ,  Steven Loyd ,  George Blouin

    发明人： Ismail Gurol ,  Robert Burns ,  Steven Loyd ,  George Blouin

    IPC分类号： A61K33/00 ,  A61K9/107 ,  A61K31/353 ,  A61K33/10 ,  A61K47/10 ,  A61K47/02 ,  A61K36/82 ,  A61K47/38 ,  A61K47/36 ,  A61K9/00 ,  A61K33/08 ,  G06Q10/06

    摘要： An orally administered composition that includes least one alkaline agent with a pH of at least 9.0 to 12.0, mixed in an aqueous vehicle with relatively high surface tension, high viscosity and lateral adhesion properties. When mixed, a low water soluble emulsion is formed that evenly coats and partially adheres to the lower section of the esophagus and the LES and forms a relatively long acting, protective barrier and partially neutralizes gastric acid. Mixed in the composition is at least one catechin 0.01 to 0.05% by weight. The alkaline agent is potassium hydroxide and the aqueous vehicle is made of hydroxypropyl methyl cellulose, polyethylene glycol or ethylene glycol and additional thickener agents capable of withstanding high pH environments, such as xanthan gum, croscarmellose sodium, and microcrystalline cellulose. Additional organoleptic agents, such as gum Arabic and polyethylene glycol, flavorings, such as sodium chloride, acesulfame potassium, sodium saccharine, and mint, and stabilizers such as colloidal silica made be added.

    Control release of fat soluble antioxidants from an oral formulation and method
    4.
    发明授权
    Control release of fat soluble antioxidants from an oral formulation and method 有权

    公开(公告)号：US10213453B2

    公开(公告)日：2019-02-26

    申请号：US15804469

    申请日：2017-11-06

    申请人： Steven Loyd ,  George Blouin ,  Newsha Farahani ,  Robert Burns

    发明人： Steven Loyd ,  George Blouin ,  Newsha Farahani ,  Robert Burns

    IPC分类号： A61K31/7048 ,  A61K9/00 ,  A61K9/50 ,  A61K31/353 ,  A61K45/06

    摘要： Oral formulation of particles made of an agglomeration of a plurality of seed granules or a single seed granule both surrounded by three layers and an outer gel coating. The seed granules are made of calcium carbonate with microscopic fissures. Disposed inside the fissures and in the interstitial spaces of the agglomerate seed granules are microscopic particles of alkali metal salts and other ions. Coating the agglomerate or single seed granules is an alkaline-resistant first layer made of microcrystalline cellulose and croscarmellose sodium that binds and protects the surrounding second layer. Surrounding the first layer is a second layer comprising a mixture of a flavonoid and polysaccharide or polypeptide binder or polymer gel. Surrounding the second layer is a third layer made of alkaline earth metal salt particles holding alkali metal hydroxide ions within a polysaccharide or polymer gel. Surrounding the third layer is at least one outer gel layer. The fourth and third layers dissolve in a low pH environment and release the fat soluble antioxidant and ions in the seed granule fissures.

    CONTROL RELEASE OF FAT SOLUABLE ANTIOXIDANTS FROM AN ORAL FORMULATION AND METHOD
    5.
    发明申请
    CONTROL RELEASE OF FAT SOLUABLE ANTIOXIDANTS FROM AN ORAL FORMULATION AND METHOD 审中-公开
    从口服制剂和方法控制脂溶性抗氧化剂的释放

    公开(公告)号：US20170020908A1

    公开(公告)日：2017-01-26

    申请号：US15131888

    申请日：2016-04-18

    申请人： Steven Loyd ,  George Blouin ,  Newsha Farahani ,  Robert Burns

    发明人： Steven Loyd ,  George Blouin ,  Newsha Farahani ,  Robert Burns

    IPC分类号： A61K31/7048 ,  A61K9/50 ,  A61K31/353 ,  A61K9/00

    CPC分类号： A61K31/7048 ,  A61K9/0019 ,  A61K9/0053 ,  A61K9/501 ,  A61K9/5047 ,  A61K9/5078 ,  A61K9/5089 ,  A61K31/353 ,  A61K45/06

    摘要： Oral formulation of particles made of an agglomeration of a plurality of seed granules or a single seed granule both surrounded by three layers and an outer gel coating. The seed granules are made of calcium carbonate with microscopic fissures. Disposed inside the fissures and in the interstitial spaces of the agglomerate seed granules are microscopic particles of alkali metal salts and other ions. Coating the agglomerate or single seed granules is an alkaline-resistant first layer made of microcrystalline cellulose and croscarmellose sodium that binds and protects the surrounding second layer. Surrounding the second layer is a third layer made of alkaline earth metal salt particles holding alkali metal hydroxide ions within a polysaccharide or polymer gel. Surrounding the third layer is at least one outer gel layer. The fourth and third layers dissolve in a low pH environment and release the fat soluble antioxidant and ions in the seed granule fissures.

    摘要翻译： 由多个种子颗粒或由三层包围的单个种子颗粒的团聚制成的颗粒的口服制剂和外部凝胶涂层。 种子颗粒由具有微观裂缝的碳酸钙制成。 在裂隙内和附聚种子颗粒的间隙中设置有碱金属盐和其它离子的微观颗粒。 附聚物或单一种子颗粒的涂覆是由微晶纤维素和交联羧甲基纤维素钠制成的耐碱性第一层，其结合并保护周围的第二层。 围绕第二层的是在多糖或聚合物凝胶内含有碱金属氢氧根离子的碱土金属盐颗粒制成的第三层。 围绕第三层是至少一个外部凝胶层。 第四和第三层溶解在低pH环境中，释放种子颗粒裂隙中的脂溶性抗氧化剂和离子。

    Method of simulating a traditional craps game with barcoded cards and video display
    7.
    发明授权
    Method of simulating a traditional craps game with barcoded cards and video display 有权
    使用条形码卡和视频显示模拟传统掷骰子游戏的方法

    公开(公告)号：US07669854B1

    公开(公告)日：2010-03-02

    申请号：US11961259

    申请日：2007-12-20

    申请人： Glenn Thompson ,  Steven Bilby ,  Steven Loyd ,  Duane D. Jennings

    发明人： Glenn Thompson ,  Steven Bilby ,  Steven Loyd ,  Duane D. Jennings

    IPC分类号： A63F5/00

    CPC分类号： A63F1/00 ,  A63F1/06 ,  A63F9/04 ,  G07F17/32 ,  G07F17/322 ,  G07F17/3293

    摘要： A method of simulating a traditional craps game experience using a specially designed deck of thirty six (36) playing cards to determine play rather than rolling dice. The deck of playing cards includes one card for each possible roll combination of a pair of dice. The deck is shuffled so that the cards are drawn at random to simulate a player rolling dice. The stickman activates the shuffler to draw a card from the shuffled deck. A bar code on the drawn card is read into a computer via a scanner and the computer then provides a visual representation of a dice roll on the monitors provided on either end of the craps table with the visualization showing the dice landing on the roll combination dictated by the drawn card. The display is activated when the shooter rolls the trackball mouse.

    摘要翻译： 使用专门设计的三十六（36）张扑克牌甲板来模拟传统的掷骰游戏体验的方法来确定游戏而不是滚动的骰子。 扑克牌甲板包括一张卡片，用于一对骰子的每个可能的卷组合。 甲板被洗牌，以便卡片随机绘制，以模拟玩家滚动的骰子。 粘贴者激活洗牌者从洗牌的甲板上画一张牌。 所绘制的卡片上的条形码通过扫描仪读入计算机，然后计算机在提供在骰子表的任一端上的监视器上提供骰子卷的可视化表示，其中显示了指示的卷组合上的骰子着陆 由拉卡。 当射手滚动轨迹球鼠标时，显示屏将被激活。

    Digital object delivery and management system with dynamically created temporary FTP access codes
    8.
    发明授权
    Digital object delivery and management system with dynamically created temporary FTP access codes 有权
    具有动态创建的临时FTP访问代码的数字对象传送和管理系统

    公开(公告)号：US07464143B2

    公开(公告)日：2008-12-09

    申请号：US10693085

    申请日：2003-10-24

    申请人： Tobid Pieper ,  Paul Martinelli ,  Brad Thompson ,  James Brentano ,  Steven Loyd

    发明人： Tobid Pieper ,  Paul Martinelli ,  Brad Thompson ,  James Brentano ,  Steven Loyd

    IPC分类号： G06F15/16 ,  G06F15/173

    CPC分类号： H04L67/06 ,  H04L69/329

    摘要： A digital object delivery/management system includes a library of stored digital objects and a shared database containing web server access codes and a mapping indicating which users are authorized to access which stored digital objects. The shared database is coupled to a file transfer protocol (FTP) server and a web server. The FTP server is additionally coupled to the library. The web server presents at least one web page providing instructions for users seeking access to digital objects contained in the library, authenticates users according to the web server access codes, generates temporary FTP access codes for use by authenticated users in accessing authorized objects at the FTP server, and redirects authenticated users to the FTP server. The FTP server authenticates users according to the temporary FTP access codes, and, upon successful authentication, makes digital objects contained in the library available to requesting users pursuant to the mapping.

    摘要翻译： 数字对象传送/管理系统包括存储的数字对象的库和包含web服务器访问代码的共享数据库以及指示哪些用户被授权访问哪个存储的数字对象的映射。 共享数据库耦合到文件传输协议（FTP）服务器和Web服务器。 FTP服务器另外耦合到库。 Web服务器提供至少一个网页，为寻求访问库中包含的数字对象的用户提供指令，根据Web服务器访问代码认证用户，生成临时FTP访问代码，以供认证用户访问FTP上的授权对象 服务器，并将经过身份验证的用户重定向到FTP服务器。 FTP服务器根据临时FTP访问代码对用户进行认证，成功认证后，使库中包含的数字对象可以根据映射向请求用户提供。

    Method of simulating a traditional roulette game experience
    9.
    发明授权
    Method of simulating a traditional roulette game experience 有权
    模拟传统轮盘游戏体验的方法

    公开(公告)号：US08066562B1

    公开(公告)日：2011-11-29

    申请号：US12034767

    申请日：2008-02-21

    申请人： Glenn Thompson ,  Steven Bilby ,  Steven Loyd ,  Duane D. Jennings

    发明人： Glenn Thompson ,  Steven Bilby ,  Steven Loyd ,  Duane D. Jennings

    IPC分类号： A63F9/24

    CPC分类号： G07F17/322 ,  A63F5/00 ,  A63F2009/2458 ,  G07F17/3293

    摘要： A method of simulating a traditional casino roulette game experience using a specially designed deck of thirty eight (38) playing cards to determine a winning number rather than via a spin of the roulette wheel. The deck includes one card for each single unique number from the roulette wheel, i.e. 00, 0, and numbers 1-36. The deck is shuffled so that the cards are drawn at random to simulate a spin of the roulette wheel. The dealer activates the shuffler to draw a card from the shuffled deck. A bar code on the drawn card is read into a computer via a scanner. Scanning the card activates the computer to provide a visual representation of a spin of the roulette wheel on a monitor located near the roulette table. The visualization shows the ball landing on the unique number of the roulette wheel dictated by the drawn card.

    摘要翻译： 使用专门设计的三十八（38）张扑克牌甲板来模拟传统赌场轮盘赌游戏体验的方法来确定获胜数量，而不是通过轮盘赌轮转动。 甲板上包含一张卡，用于从轮盘赌轮中的每一个唯一号码，即00,0和1-36。 甲板被洗牌，以便随机绘制牌，以模拟轮盘赌轮的旋转。 经销商激活洗牌者从洗牌的甲板上画一张牌。 绘图卡上的条形码通过扫描仪读入计算机。 扫描卡片激活计算机，以提供轮盘赌轮轮旋转的可视化表示，该轮盘在轮盘赌桌附近的监视器上。 可视化显示了由绘制牌所规定的唯一的轮盘赌数量的球落地。