公开(公告)号：US08706189B2

公开(公告)日：2014-04-22

申请号：US12458313

申请日：2009-07-08

申请人： Jürgen Hagen ,  Benedikt Hartinger ,  Volker Matschl ,  Rainer Paul

发明人： Jürgen Hagen ,  Benedikt Hartinger ,  Volker Matschl ,  Rainer Paul

IPC分类号： A61B5/055 ,  A61B19/00

CPC分类号： G01R33/481 ,  A61B5/0035 ,  A61B5/0555 ,  A61B6/037 ,  A61B6/4417 ,  G01R33/30 ,  G01R33/307 ,  G01R33/34007 ,  G01R33/34046 ,  G01R33/34076

摘要： A combined PET/MRI device is disclosed. In at least one embodiment, the PET/MRI device includes an MRI unit for exciting nuclear spins in an examination volume and for receiving signals generated by the excitation in the examination volume, and a PET unit with a detector which surrounds the examination volume at least in part and is used for detecting radiation emanating from the examination volume, with, firstly, damping of the radiation emitted by the examination volume and, secondly, undesired interactions with electromagnetic fields of the MRI unit on the components of the PET/MRI device arranged between the examination volume and the detector being avoided due to the material properties and/or structural design of the components. Corresponding components such as, for example, patient couches, bearing or support apparatuses and local coils, are both MRI and PET compatible.

摘要翻译： 公开了一种组合的PET / MRI装置。 在至少一个实施例中，PET / MRI装置包括用于在检查体积中激发核自旋并用于接收由检查体积中的激发产生的信号的MRI单元，以及具有至少围绕检查体积的检测器的PET单元 部分地用于检测从检查体积发出的辐射，首先是由检查体积发射的辐射的阻尼;其次，与设置在PET / MRI装置的部件上的MRI单元的电磁场的不期望的相互作用 由于部件的材料性质和/或结构设计而在检查体积和检测器之间避免。 相应的部件，例如患者的沙发，轴承或支撑装置和局部线圈，都是MRI和PET兼容的。

公开(公告)号：US20100010337A1

公开(公告)日：2010-01-14

申请号：US12458313

申请日：2009-07-08

申请人： Jürgen Hagen ,  Benedikt Hartinger ,  Volker Matschl ,  Rainer Paul

发明人： Jürgen Hagen ,  Benedikt Hartinger ,  Volker Matschl ,  Rainer Paul

IPC分类号： A61B5/055

CPC分类号： G01R33/481 ,  A61B5/0035 ,  A61B5/0555 ,  A61B6/037 ,  A61B6/4417 ,  G01R33/30 ,  G01R33/307 ,  G01R33/34007 ,  G01R33/34046 ,  G01R33/34076

摘要： A combined PET/MRI device is disclosed. In at least one embodiment, the PET/MRI device includes an MRI unit for exciting nuclear spins in an examination volume and for receiving signals generated by the excitation in the examination volume, and a PET unit with a detector which surrounds the examination volume at least in part and is used for detecting radiation emanating from the examination volume, with, firstly, damping of the radiation emitted by the examination volume and, secondly, undesired interactions with electromagnetic fields of the MRI unit on the components of the PET/MRI device arranged between the examination volume and the detector being avoided due to the material properties and/or structural design of the components. Corresponding components such as, for example, patient couches, bearing or support apparatuses and local coils, are both MRI and PET compatible.

摘要翻译： 公开了一种组合的PET / MRI装置。 在至少一个实施例中，PET / MRI装置包括用于在检查体积中激发核自旋并用于接收由检查体积中的激发产生的信号的MRI单元，以及具有至少围绕检查体积的检测器的PET单元 部分地用于检测从检查体积发出的辐射，首先是由检查体积发射的辐射的阻尼;其次，与设置在PET / MRI装置的部件上的MRI单元的电磁场的不期望的相互作用 由于部件的材料性质和/或结构设计而在检查体积和检测器之间避免。 相应的部件，例如患者的沙发，轴承或支撑装置和局部线圈，都是MRI和PET兼容的。

公开(公告)号：US07675028B2

公开(公告)日：2010-03-09

申请号：US12144063

申请日：2008-06-23

申请人： Johannes Breuer ,  Rainer Paul ,  Volker Matschl ,  A. Andrew Carey

发明人： Johannes Breuer ,  Rainer Paul ,  Volker Matschl ,  A. Andrew Carey

IPC分类号： G01D18/00

CPC分类号： A61B6/037 ,  A61B6/583 ,  G21G4/06

摘要： A phantom for use in generating a normalization data set to be used in PET scanning (particularly integrated MR/PET scanning) is disclosed. The phantom features radiation activity distributed throughout a foam material. The foam—e.g., a polyurethane foam—may be produced by reacting two liquids, one of which is emulsified with water in which Ge68 has been dissolved. The foam produced thereby exhibits uniform distribution of radioactivity and a long mean free path for 511 keV gamma particles—two attributes that are important attributes of a PET phantom.

摘要翻译： 公开了用于生成用于PET扫描（特别是集成MR / PET扫描）的归一化数据集的体模。 幻影具有分布在泡沫材料中的辐射活性特征。 泡沫 - 例如，聚氨酯泡沫 - 可以通过使两种液体反应来制备，其中一种液体与其中已经溶解了Ge68的水乳化。 由此产生的泡沫表现出对于511Kevγ粒子的放射性均匀分布和长平均自由程 - 这两个属性是PET幻影的重要属性。

公开(公告)号：US20090314933A1

公开(公告)日：2009-12-24

申请号：US12144063

申请日：2008-06-23

申请人： Johannes Breuer ,  Rainer Paul ,  Volker Matschl ,  A. Andrew Carey

发明人： Johannes Breuer ,  Rainer Paul ,  Volker Matschl ,  A. Andrew Carey

IPC分类号： G01D18/00

CPC分类号： A61B6/037 ,  A61B6/583 ,  G21G4/06

摘要： A phantom for use in generating a normalization data set to be used in PET scanning (particularly integrated MR/PET scanning) is disclosed. The phantom features radiation activity distributed throughout a foam material. The foam—e.g., a polyurethane foam—may be produced by reacting two liquids, one of which is emulsified with water in which Ge68 has been dissolved. The foam produced thereby exhibits uniform distribution of radioactivity and a long mean free path for 511 keV gamma particles—two attributes that are important attributes of a PET phantom.

摘要翻译： 公开了用于生成用于PET扫描（特别是集成MR / PET扫描）的归一化数据集的体模。 幻影具有分布在泡沫材料中的辐射活性特征。 泡沫 - 例如，聚氨酯泡沫 - 可以通过使两种液体反应来制备，其中一种液体与其中已经溶解了Ge68的水乳化。 由此产生的泡沫表现出对于511Kevγ粒子的放射性均匀分布和长平均自由程 - 这两个属性是PET幻影的重要属性。

公开(公告)号：US20080269594A1

公开(公告)日：2008-10-30

申请号：US12109605

申请日：2008-04-25

申请人： Rainer Paul ,  Matthias J. Schmand ,  Charles H. Hayden ,  James Corbeil ,  Christian J. Michel ,  Ziad Burbar ,  Volker Matschl

发明人： Rainer Paul ,  Matthias J. Schmand ,  Charles H. Hayden ,  James Corbeil ,  Christian J. Michel ,  Ziad Burbar ,  Volker Matschl

IPC分类号： A61B5/055 ,  A61B6/00

CPC分类号： G01R33/481 ,  A61B6/037 ,  A61B6/583 ,  G01R33/58 ,  G01T1/1603

摘要： A phantom and method are provided for co-registering a magnetic resonance image and a nuclear medical image. The phantom includes a first housing defining a first chamber configured to receive a magnetic resonance material upon which magnetic resonance imaging can be performed in order to produce the magnetic resonance image. The phantom also includes three or more second housings configured to be attached to the first housing, where the second housings each define a second chamber configured to receive a radioactive material upon which nuclear imaging can be performed in order to produce the nuclear medical image and upon which the magnetic imaging can be performed in order to produce the magnetic resonance image. The first chamber has a volumetric capacity that is larger than a volumetric capacity of each second chamber.

摘要翻译： 提供了用于共同配准磁共振图像和核医学图像的体模和方法。 幻影包括限定第一室的第一壳体，其被配置为接收磁共振材料，在该共振材料上可进行磁共振成像以产生磁共振图像。 该幻影还包括构造成附接到第一壳体的三个或更多个第二壳体，其中第二壳体每个限定第二室，所述第二室被构造成接收放射性材料，在该第二室上可以执行核成像以产生核医学图像， 可以进行磁性成像以产生磁共振图像。 第一室具有大于每个第二室的容积的容积。

公开(公告)号：US07965080B2

公开(公告)日：2011-06-21

申请号：US12560027

申请日：2009-09-15

申请人： Johannes Breuer ,  A. Andrew Carey ,  Xinli Liu ,  Volker Matschl ,  Rainer Paul

发明人： Johannes Breuer ,  A. Andrew Carey ,  Xinli Liu ,  Volker Matschl ,  Rainer Paul

IPC分类号： G01V3/00

CPC分类号： G01R33/58 ,  G01R33/481

摘要： A phantom for use in quality control measurement of a fully integrated magnetic resonance/PET scanner is disclosed. The phantom features radiation activity distributed throughout an electrically conductive binder. Suitably, the binder is elastomeric and includes carbon fibers distributed throughout it to set the conductivity of the phantom to a desired level. The phantom is applicable to various multimodality integrated medical imaging systems such as MR/SPECT and MR/CT in addition to MR/PET.

摘要翻译： 公开了一种用于完全集成的磁共振/ PET扫描仪的质量控制测量的幻影。 幻影具有分布在整个导电粘合剂中的辐射活性特征。 适当地，粘合剂是弹性的并且包括分布在其中的碳纤维以将体模的导电性设定到期望的水平。 幻影适用于MR / PET等各种多模式综合医学成像系统，如MR / SPECT和MR / CT。

公开(公告)号：US07768261B2

公开(公告)日：2010-08-03

申请号：US12109605

申请日：2008-04-25

申请人： Rainer Paul ,  Matthias J. Schmand ,  Charles H. Hayden, Jr. ,  James Corbeil ,  Christian J. Michel ,  Ziad Burbar ,  Volker Matschl

发明人： Rainer Paul ,  Matthias J. Schmand ,  Charles H. Hayden, Jr. ,  James Corbeil ,  Christian J. Michel ,  Ziad Burbar ,  Volker Matschl

IPC分类号： G01V3/00

CPC分类号： G01R33/481 ,  A61B6/037 ,  A61B6/583 ,  G01R33/58 ,  G01T1/1603

摘要： A phantom and method are provided for co-registering a magnetic resonance image and a nuclear medical image. The phantom includes a first housing defining a first chamber configured to receive a magnetic resonance material upon which magnetic resonance imaging can be performed in order to produce the magnetic resonance image. The phantom also includes three or more second housings configured to be attached to the first housing, where the second housings each define a second chamber configured to receive a radioactive material upon which nuclear imaging can be performed in order to produce the nuclear medical image and upon which the magnetic imaging can be performed in order to produce the magnetic resonance image. The first chamber has a volumetric capacity that is larger than a volumetric capacity of each second chamber.

摘要翻译： 提供了用于共同配准磁共振图像和核医学图像的体模和方法。 幻影包括限定第一室的第一壳体，其被配置为接收磁共振材料，在该共振材料上可进行磁共振成像以产生磁共振图像。 该幻影还包括构造成附接到第一壳体的三个或更多个第二壳体，其中第二壳体每个限定第二室，所述第二室被构造成接收放射性材料，在该第二室上可以执行核成像以产生核医学图像， 可以进行磁性成像以产生磁共振图像。 第一室具有大于每个第二室的容积的容积。

公开(公告)号：US20100066372A1

公开(公告)日：2010-03-18

申请号：US12560027

申请日：2009-09-15

申请人： Johannes Breuer ,  A. Andrew Carey ,  Xinli Liu ,  Volker Matschi ,  Rainer Paul

发明人： Johannes Breuer ,  A. Andrew Carey ,  Xinli Liu ,  Volker Matschi ,  Rainer Paul

IPC分类号： G01R33/44

CPC分类号： G01R33/58 ,  G01R33/481

摘要： A phantom for use in quality control measurement of a fully integrated magnetic resonance/PET scanner is disclosed. The phantom features radiation activity distributed throughout an electrically conductive binder. Suitably, the binder is elastomeric and includes carbon fibers distributed throughout it to set the conductivity of the phantom to a desired level. The phantom is applicable to various multimodality integrated medical imaging systems such as MR/SPECT and MR/CT in addition to MR/PET.

摘要翻译： 公开了一种用于完全集成的磁共振/ PET扫描仪的质量控制测量的幻影。 幻影具有分布在整个导电粘合剂中的辐射活性特征。 适当地，粘合剂是弹性的并且包括分布在其中的碳纤维以将体模的导电性设定到期望的水平。 幻影适用于MR / PET等各种多模式综合医学成像系统，如MR / SPECT和MR / CT。