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    Device and method for high intensity focused ultrasound ablation with acoustic lens
    3.
    发明申请
    Device and method for high intensity focused ultrasound ablation with acoustic lens 有权
    声透镜高强度聚焦超声消融的装置和方法

    公开(公告)号：US20080194965A1

    公开(公告)日：2008-08-14

    申请号：US11703783

    申请日：2007-02-08

    申请人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    发明人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    IPC分类号： A61B17/00

    CPC分类号： A61N7/02 ,  A61N2007/0056 ,  A61N2007/006 ,  A61N2007/0078

    摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.

    摘要翻译： 高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接 在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。 为了制造简单，第一表面通常是平坦的或单调曲线的。 透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。 考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。 通过模制，铸造或热成型镜片进一步简化制造。

    System and method for transmitting analog signals with a modulating retroreflector and hybrid amplitude and frequency modulation
    4.
    发明申请
    System and method for transmitting analog signals with a modulating retroreflector and hybrid amplitude and frequency modulation 有权
    用调制后向反射器和混合幅度和频率调制传输模拟信号的系统和方法

    公开(公告)号：US20070189779A1

    公开(公告)日：2007-08-16

    申请号：US11499988

    申请日：2006-08-01

    申请人： James Murphy ,  William Rabinovich ,  G. Gilbreath ,  Peter Goetz

    发明人： James Murphy ,  William Rabinovich ,  G. Gilbreath ,  Peter Goetz

    IPC分类号： H04B10/04 ,  H04B10/12

    CPC分类号： H04B10/2587

    摘要： A system and method for encoding an analog input signal for optical transmission, including driving a voltage controlled oscillator with an analog input signal to produce a frequency modulated electrical signal having a frequency proportional to the amplitude of the input signal, and applying the frequency modulated electrical signal to a multiple quantum well modulating retroreflector. The retroreflector receives optical energy from a laser source and modulates the optical energy with the frequency modulated signal to produce an output optical signal.

    摘要翻译： 一种用于对用于光传输的模拟输入信号进行编码的系统和方法，包括用模拟输入信号驱动压控振荡器以产生具有与输入信号的幅度成正比的频率的调频电信号，以及施加频率调制电 信号到多量子阱调制后向反射器。 后向反射器从激光源接收光能，并用调频信号调制光能以产生输出光信号。

    Process for preparing glycide by epoxidation using polymeric organosiloxane ammonium salts of oxoacids of the elements V, Nb, Ta, Mo, and W
    5.
    发明授权
    Process for preparing glycide by epoxidation using polymeric organosiloxane ammonium salts of oxoacids of the elements V, Nb, Ta, Mo, and W 失效
    使用元素V，Nb，Ta，Mo和W的含氧酸的聚合有机硅氧烷铵盐通过环氧化制备糖苷的方法

    公开(公告)号：US5286885A

    公开(公告)日：1994-02-15

    申请号：US53248

    申请日：1993-04-28

    申请人： Peter Goetz ,  Stefan Wieland ,  Peter Panster ,  Gustaaf Goor ,  Rainer Siegmeier

    发明人： Peter Goetz ,  Stefan Wieland ,  Peter Panster ,  Gustaaf Goor ,  Rainer Siegmeier

    IPC分类号： C08G77/54 ,  C08G77/58 ,  C07D301/12 ,  C07D303/14

    CPC分类号： C08G77/54 ,  C08G77/58

    摘要： The invention relates to polymeric organosiloxane ammonium salts having a silica-like skeleton and including units of Formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are identical or different and signify a group of Formula (II): ##STR2## wherein R.sup.5 is an alkylene group and the oxygen atoms are saturated by silicon atoms of additional groups corresponding to Formula (II), optionally with the insertion of cross-linking agents; R.sup.3 represents groups corresponding to R.sup.1 or R.sup.2, or hydrogen or an alkyl group; R.sup.4 represents hydrogen or an alkyl group; x is the charge number of an oxo anion of a monooxo-, isopolyoxo- or heteropolyoxo acid of the elements vanadium, niobium, tantalum, molybdenum or tungsten; and oxo groups of the X anion also may be replaced by peroxo groups. The invention also includes methods of preparing the salts of Formula (I) from salts of the type (R.sup.1 R.sup.2 R.sup.3 R.sup.4 N.sup.+).sub.y Y wherein Y is different from X. The invention further includes the use of the salts of Formula (I) as catalyst for oxidation reactions using peroxo compounds as an oxidation agent.

    摘要翻译： 本发明涉及具有二氧化硅样骨架并包括式（I）的单元的聚合有机硅氧烷铵盐：（*化学结构*）（I）其中R1和R2相同或不同并且表示式（II）的基团： （*化学结构*）（II）其中R5是亚烷基并且氧原子被对应于式（II）的另外的基团的硅原子饱和，任选地插入交联剂; R3表示对应于R1或R2的基团，或氢或烷基; R4表示氢或烷基; x是元素钒，铌，钽，钼或钨元素的单氧，异羟基或杂多酸的氧阴离子的电荷数; X阴离子的氧基也可以被过氧基取代。 本发明还包括从其中Y不同于X的类型（R 1 R 2 R 3 R 4 N +）y Y的盐制备式（I）的盐的方法。本发明还包括使用式（I）的盐作为氧化反应的催化剂，其使用 过氧化合物作为氧化剂。

    Device and method for high intensity focused ultrasound ablation with acoustic lens
    6.
    发明授权
    Device and method for high intensity focused ultrasound ablation with acoustic lens 有权
    声透镜高强度聚焦超声消融的装置和方法

    公开(公告)号：US08382689B2

    公开(公告)日：2013-02-26

    申请号：US11703783

    申请日：2007-02-08

    申请人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    发明人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    IPC分类号： A61H1/00

    CPC分类号： A61N7/02 ,  A61N2007/0056 ,  A61N2007/006 ,  A61N2007/0078

    摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.

    摘要翻译： 高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接 在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。 为了制造简单，第一表面通常是平坦的或单调曲线的。 透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。 考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。 通过模制，铸造或热成型镜片进一步简化制造。

    High intensity focused ultrasound transducer with acoustic lens
    7.
    发明授权
    High intensity focused ultrasound transducer with acoustic lens 有权
    高强度聚焦超声波换能器与声透镜

    公开(公告)号：US08102734B2

    公开(公告)日：2012-01-24

    申请号：US11703784

    申请日：2007-02-08

    申请人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    发明人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    IPC分类号： A61B8/00

    CPC分类号： A61N7/02 ,  A61B8/4272 ,  A61B17/2251

    摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.

    摘要翻译： 高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接 在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。 为了制造简单，第一表面通常是平坦的或单调曲线的。 透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。 考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。 通过模制，铸造或热成型镜片进一步简化制造。

    High intensity focused ultrasound transducer with acoustic lens
    8.
    发明申请
    High intensity focused ultrasound transducer with acoustic lens 有权
    高强度聚焦超声波换能器与声透镜

    公开(公告)号：US20080194967A1

    公开(公告)日：2008-08-14

    申请号：US11703784

    申请日：2007-02-08

    申请人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    发明人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    IPC分类号： A61B8/00

    CPC分类号： A61N7/02 ,  A61B8/4272 ,  A61B17/2251

    摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.

    摘要翻译： 高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接 在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。 为了制造简单，第一表面通常是平坦的或单调曲线的。 透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。 考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。 通过模制，铸造或热成型镜片进一步简化制造。