专利检索 ap:("Jack Z. Gougoutas" OR "Hildegard Lobinger" OR "Srividya Ramakrishnan" OR "Prashant P. Deshpande" OR "Jeffrey T. Bien" OR "Chiajen Lai" OR "Chenchi Wang" OR "Peter Riebel" OR "John Anthony Grosso" OR "Alexandra A. Nirschl" OR "Janak Singh" OR "John D. DiMarco") AND inv:"Chiajen Lai" 第 1 页

1.

发明申请
CRYSTAL STRUCTURES OF SGLT2 INHIBITORS AND PROCESSES FOR PREPARING SAME 有权
标题翻译： SGLT2抑制剂的晶体结构及其制备方法

公开(公告)号：US20110172176A1

公开(公告)日：2011-07-14

申请号：US13049712

申请日：2011-03-16

申请人： Jack Z. Gougoutas , Hildegard Lobinger , Srividya Ramakrishnan , Prashant P. Deshpande , Jeffrey T. Bien , Chiajen Lai , Chenchi Wang , Peter Riebel , John Anthony Grosso , Alexandra A. Nirschl , Janak Singh , John D. DiMarco

发明人： Jack Z. Gougoutas , Hildegard Lobinger , Srividya Ramakrishnan , Prashant P. Deshpande , Jeffrey T. Bien , Chiajen Lai , Chenchi Wang , Peter Riebel , John Anthony Grosso , Alexandra A. Nirschl , Janak Singh , John D. DiMarco

IPC分类号： A61K31/7034 , C07H15/207 , C07H1/00 , A61P3/04 , A61P3/10 , A61P17/02 , A61P3/06 , A61P9/10 , A61P9/12

CPC分类号： C07H15/207 , A61K31/7034 , A61K45/06 , A61P3/10 , C07H7/04

摘要： The present invention relates to physical crystal structures of a compound of the formula I: wherein R1, R2, R2a, R3 and R4 are as defined herein, especially pharmaceutical compositions containing structures of compound I or II, processes for preparing same, intermediates used in preparing same, and methods of treating diseases such as diabetes using such structures.

摘要翻译： 本发明涉及式I化合物的物理结晶结构：其中R1，R2，R2a，R3和R4如本文所定义，特别是含有化合物I或II结构的药物组合物，其制备方法，制备方法以及使用这种结构治疗糖尿病等疾病的方法。

2.

发明授权
Crystal structures of SGLT2 inhibitors and processes for preparing same 有权
标题翻译： SGLT2抑制剂的晶体结构及其制备方法

公开(公告)号：US07919598B2

公开(公告)日：2011-04-05

申请号：US11765481

申请日：2007-06-20

申请人： Jack Z. Gougoutas , Hildegard Lobinger , Srividya Ramakrishnan , Prashant P. Deshpande , Jeffrey T. Bien , Chiajen Lai , Chenchi Wang , Peter Riebel , John Anthony Grosso , Alexandra A. Nirschl , Janak Singh , John D. DiMarco

发明人： Jack Z. Gougoutas , Hildegard Lobinger , Srividya Ramakrishnan , Prashant P. Deshpande , Jeffrey T. Bien , Chiajen Lai , Chenchi Wang , Peter Riebel , John Anthony Grosso , Alexandra A. Nirschl , Janak Singh , John D. DiMarco

IPC分类号： C07H7/04 , C07H1/00 , A61K31/70

CPC分类号： C07H15/207 , A61K31/7034 , A61K45/06 , A61P3/10 , C07H7/04

摘要： The present invention relates to physical crystal structures of a compound of the formula I: wherein R1, R2, R2a, R3 and R4 are as defined herein, especially pharmaceutical compositions containing structures of compound I or II, processes for preparing same, intermediates used in preparing same, and methods of treating diseases such as diabetes using such structures.

摘要翻译： 本发明涉及式I化合物的物理结晶结构：其中R1，R2，R2a，R3和R4如本文所定义，特别是含有化合物I或II结构的药物组合物，其制备方法，制备方法以及使用这种结构治疗糖尿病等疾病的方法。

3.

发明授权
Crystal structures of SGLT2 inhibitors and processes for preparing same 有权
标题翻译： SGLT2抑制剂的晶体结构及其制备方法

公开(公告)号：US08501698B2

公开(公告)日：2013-08-06

申请号：US13049712

申请日：2011-03-16

申请人： Jack Z. Gougoutas , Hildegard Lobinger , Srividya Ramakrishnan , Prashant P. Deshpande , Jeffrey T. Bien , Chiajen Lai , Chenchi Wang , Peter Riebel , John Anthony Grosso , Alexandra A. Nirschl , Janak Singh , John D. DiMarco

发明人： Jack Z. Gougoutas , Hildegard Lobinger , Srividya Ramakrishnan , Prashant P. Deshpande , Jeffrey T. Bien , Chiajen Lai , Chenchi Wang , Peter Riebel , John Anthony Grosso , Alexandra A. Nirschl , Janak Singh , John D. DiMarco

IPC分类号： A61K31/351 , C07D309/10 , C07H7/04

CPC分类号： C07H15/207 , A61K31/7034 , A61K45/06 , A61P3/10 , C07H7/04

摘要： The present invention relates to physical crystal structures of a compound of the formula I: wherein R1, R2, R2a, R3 and R4 are as defined herein, especially pharmaceutical compositions containing structures of compound I or II, processes for preparing same, intermediates used in preparing same, and methods of treating diseases such as diabetes using such structures.

摘要翻译： 本发明涉及式I化合物的物理结晶结构：其中R1，R2，R2a，R3和R4如本文所定义，特别是含有化合物I或II结构的药物组合物，其制备方法，制备方法以及使用这种结构治疗糖尿病等疾病的方法。

4.

发明申请
CRYSTAL STRUCTURES OF SGLT2 INHIBITORS AND PROCESSES FOR PREPARING SAME 有权
标题翻译： SGLT2抑制剂的晶体结构及其制备方法

公开(公告)号：US20080004336A1

公开(公告)日：2008-01-03

申请号：US11765481

申请日：2007-06-20

申请人： Jack Gougoutas , Hildegard Lobinger , Srividya Ramakrishnan , Prashant Deshpande , Jeffrey Bien , Chiajen Lai , Chenchi Wang , Peter Riebel , John Grosso , Alexandra Nirschl , Janak Singh , John DiMarco

发明人： Jack Gougoutas , Hildegard Lobinger , Srividya Ramakrishnan , Prashant Deshpande , Jeffrey Bien , Chiajen Lai , Chenchi Wang , Peter Riebel , John Grosso , Alexandra Nirschl , Janak Singh , John DiMarco

IPC分类号： C07D309/10 , A61K31/351 , A61P3/00 , A61P3/10

CPC分类号： C07H15/207 , A61K31/7034 , A61K45/06 , A61P3/10 , C07H7/04

摘要： The present invention relates to physical crystal structures of a compound of the formula I: wherein R1, R2, R2a, R3 and R4 are as defined herein, especially pharmaceutical compositions containing structures of compound I or II, processes for preparing same, intermediates used in preparing same, and methods of treating diseases such as diabetes using such structures.

摘要翻译： 本发明涉及式I化合物的物理结晶结构：其中R 1，R 2，R 2a，R SUP， > 3和R 4如本文所定义的，特别是含有化合物I或II结构的药物组合物，其制备方法，用于制备其的中间体，以及治疗疾病如使用这种结构的糖尿病。

5.

发明申请
Methods of Producing C-Aryl Glucoside SGLT2 Inhibitors 审中-公开
标题翻译：生产C-Aryl Glucoside SGLT2抑制剂的方法

公开(公告)号：US20110201795A1

公开(公告)日：2011-08-18

申请号：US13093430

申请日：2011-04-25

申请人： Prashant P. Deshpande , Bruce A. Ellsworth , Janak Singh , Theodor W. Denzel , Chiajen Lai , Gerard Crispino , Michael E. Randazzo , Jack Z. Gougoutas

发明人： Prashant P. Deshpande , Bruce A. Ellsworth , Janak Singh , Theodor W. Denzel , Chiajen Lai , Gerard Crispino , Michael E. Randazzo , Jack Z. Gougoutas

IPC分类号： C07H1/00 , C07H23/00 , C07H15/02

CPC分类号： C07H23/00 , C07H5/04 , C07H5/06 , C07H7/00 , C07H15/207

摘要： Method for the production of C-aryl glucoside SGLT2 inhibitors useful for the treatment of diabetes and related diseases. and intermediates thereof. The C-aryl glucosides may be complexed with amino acid complex forming reagents.

摘要翻译： 生产用于治疗糖尿病和相关疾病的C-芳基葡萄糖苷SGLT2抑制剂的方法。及其中间体。 C-芳基葡糖苷可以与形成氨基酸复合物的试剂络合。

6.

发明授权
Methods of producing C-aryl glucoside SGLT2 inhibitors 有权
标题翻译：生产C-芳基葡萄糖苷SGLT2抑制剂的方法

公开(公告)号：US07932379B2

公开(公告)日：2011-04-26

申请号：US11764839

申请日：2007-06-19

申请人： Prashant P. Deshpande , Bruce A. Ellsworth , Janak Singh , Theodor W. Denzel , Chiajen Lai , Gerard Crispino , Michael E. Randazzo , Jack Z. Gougoutas

发明人： Prashant P. Deshpande , Bruce A. Ellsworth , Janak Singh , Theodor W. Denzel , Chiajen Lai , Gerard Crispino , Michael E. Randazzo , Jack Z. Gougoutas

IPC分类号： C07H1/00

CPC分类号： C07H23/00 , C07H5/04 , C07H5/06 , C07H7/00 , C07H15/207

摘要： Method for the production of C-aryl glucoside SGLT2 inhibitors useful for the treatment of diabetes and related diseases. and intermediates thereof. The C-aryl glucosides may be complexed with amino acid complex forming reagents.

摘要翻译： 生产用于治疗糖尿病和相关疾病的C-芳基葡萄糖苷SGLT2抑制剂的方法。及其中间体。 C-芳基葡糖苷可以与形成氨基酸复合物的试剂络合。

7.

发明授权
Methods of producing C-aryl glucoside SGLT2 inhibitors 有权
标题翻译：生产C-芳基葡萄糖苷SGLT2抑制剂的方法

公开(公告)号：US07375213B2

公开(公告)日：2008-05-20

申请号：US10745075

申请日：2003-12-23

申请人： Prashant P. Deshpande , Bruce A. Ellsworth , Janak Singh , Theodor W. Denzel , Chiajen Lai , Gerard Crispino , Michael E. Randazzo , Jack Z. Gougoutas

发明人： Prashant P. Deshpande , Bruce A. Ellsworth , Janak Singh , Theodor W. Denzel , Chiajen Lai , Gerard Crispino , Michael E. Randazzo , Jack Z. Gougoutas

IPC分类号： C07H15/203 , C07H15/20 , C07H1/00

CPC分类号： C07H23/00 , C07H5/04 , C07H5/06 , C07H7/00 , C07H15/207

摘要： Method for the production of C-aryl glucoside SGLT2 inhibitors useful for the treatment of diabetes and related diseases. and intermediates thereof. The C-aryl glucosides may be complexed with amino acid complex forming reagents.

摘要翻译： 生产用于治疗糖尿病和相关疾病的C-芳基葡萄糖苷SGLT2抑制剂的方法。及其中间体。 C-芳基葡糖苷可以与形成氨基酸复合物的试剂络合。