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15 条记录 (耗时 0.027 秒)

    Processes of making North American ginseng fractions, products containing them, and use as immunomodulators
    7.
    发明授权
    Processes of making North American ginseng fractions, products containing them, and use as immunomodulators 有权
    制作北美西参人造片，含有它们的产品，用作免疫调节剂的方法

    公开(公告)号：US07067160B2

    公开(公告)日：2006-06-27

    申请号：US10187289

    申请日：2002-07-02

    申请人： Jacqueline J. Shan ,  Peter K. T. Pang ,  Buhan Huang ,  Lei Ling

    发明人： Jacqueline J. Shan ,  Peter K. T. Pang ,  Buhan Huang ,  Lei Ling

    IPC分类号： A61K35/78

    CPC分类号： A61K39/39 ,  A61K36/258 ,  A61K2039/55583 ,  A61K2039/55588 ,  Y10S514/885

    摘要： This invention is directed towards processes of making fractions from North American ginseng and to compositions containing these fractions. This invention is also directed towards methods of methods of preparing pharmaceuticals containing these fractions. Additionally, this invention is directed towards methods of stimulating the production of immunoglobins by administering fractions of this invention and also to methods of activating B-lymphocyte proliferation and antibody production by administering fractions of this invention. This invention is also directed towards a method of stimulating the production of IL-16, IL-1, and/or TNF-α in cells by administering a fraction of this invention.

    摘要翻译： 本发明涉及从北美人参制成级分的方法以及含有这些级分的组合物。 本发明还涉及制备含有这些级分的药物的方法的方法。 此外，本发明涉及通过施用本发明的级分刺激免疫球蛋白的产生的方法，还涉及通过施用本发明的级分来激活B淋巴细胞增殖和抗体产生的方法。 本发明还涉及通过施用本发明的一部分来刺激细胞中IL-16，IL-1和/或TNF-α的产生的方法。

    Hypericin and hypericum extract: specific T-type calcium channel blocker, and their use as T-type calcium channel targeted therapeutics
    10.
    发明授权
    Hypericin and hypericum extract: specific T-type calcium channel blocker, and their use as T-type calcium channel targeted therapeutics 有权
    金丝桃素和金丝桃提取物：特异性T型钙通道阻断剂，其作为T型钙通道靶向治疗剂

    公开(公告)号：US07195783B2

    公开(公告)日：2007-03-27

    申请号：US09481572

    申请日：2000-01-11

    申请人： Jacqueline J. Shan ,  Xi-Chen Wu ,  Peter K. T. Pang ,  Lei Ling

    发明人： Jacqueline J. Shan ,  Xi-Chen Wu ,  Peter K. T. Pang ,  Lei Ling

    IPC分类号： A01N65/00

    CPC分类号： A61K31/235 ,  A61K31/12 ,  A61K31/185 ,  A61K31/192 ,  A61K36/38

    摘要： Hypericin has been shown to specifically inhibited T-type calcium channel activity. Hypericum extract containing hypericin also inhibited T-type calcium channel activity. Moreover, other chemicals in Hypericum extract showed a synergistic effect to hypericin. In view of this, hypericin or hypericin-containing Hypericum extract can be used as T-channel blockers. Hypericum extract, extract of other species of the Hypericum genus, extract of other plants containing hypericin, hypericin, hypericin derivatives, hypericin analogs, such as pseudohypericin, and other hypericum extract constituents can be used as therapeutics targeted at T-type calcium channels for treatment of diseases associated with T-channel abnormality. Methods for administering hypericin and hypericum extract are disclosed.

    摘要翻译： 已显示金丝桃素特异性抑制T型钙通道活性。 含金丝桃素的金丝桃提取物也抑制T型钙通道活性。 此外，金丝桃提取物中的其他化学物质显示出对金丝桃素的协同作用。 鉴于此，金丝桃素或含金丝桃酸的金丝桃提取物可用作T通道阻断剂。 金丝桃提取物，金丝桃属的其他物种的提取物，含有金丝桃素的金丝桃素，金丝桃素，金丝桃素衍生物，金丝桃素类似物例如假倍他辛和其他金丝桃提取物成分的提取物可用作靶向T型钙通道的治疗剂用于治疗 的与T通道异常相关的疾病。 公开了金丝桃素和金丝桃提取物的施用方法。