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1.发明授权Genetically engineered recombinant Escherichia coli producing L-tryptophan having originally L-phenylalanine productivity, and method for producing L-tryptophan using the microorganism 有权生产L-苯丙氨酸生产力的基因工程重组大肠杆菌生产L-色氨酸，以及使用该微生物生产L-色氨酸的方法公开(公告)号：US08945907B2
公开(公告)日：2015-02-03
申请号：US12520350
申请日：2007-12-28
申请人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
发明人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
CPC分类号： C12P13/227 , C12N9/88 , C12N15/52
摘要： The present invention relates to a microorganism having L-tryptophan productivity and a method for producing L-tryptophan using the same. More precisely, the present invention relates to the recombinant E. coli strain CJ600 (KCCM 10812P) having tryptophan productivity produced from the mutant form (KFCC 10066) of E. coli having L-phenylalanine productivity, wherein tryptophan auxotrophy is released, L-phenylalanine biosynthesis is blocked but tryptophan productivity is enhanced by reinforcing the gene involved in tryptophan biosynthesis, and a method of producing L-tryptophan using the same.
摘要翻译： 本发明涉及具有L-色氨酸生产力的微生物和使用其的L-色氨酸的生产方法。 更准确地说，本发明涉及由具有L-苯丙氨酸生产力的大肠杆菌的突变形式（KFCC 10066）产生的具有色氨酸生产力的重组大肠杆菌菌株CJ600（KCCM 10812P），其中色氨酸营养缺陷型被释放，L-苯丙氨酸 生物合成被阻断，但通过加强色氨酸生物合成中涉及的基因来增强色氨酸的生产力，以及使用其生产L-色氨酸的方法。
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公开(公告)号：US08569066B2
公开(公告)日：2013-10-29
申请号：US13548044
申请日：2012-07-12
申请人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
发明人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
CPC分类号： C12P13/227 , C12N9/88 , C12N15/52
摘要： The present invention relates to a microorganism having L-tryptophan productivity and a method for producing L-tryptophan using the same. More precisely, the present invention relates to the recombinant E. coli strain CJ600 (KCCM 10812P) having tryptophan productivity produced from the mutant form (KFCC 10066) of E. coli having L-phenylalanine productivity, wherein tryptophan auxotrophy is released, L-phenylalanine biosynthesis is blocked but tryptophan productivity is enhanced by reinforcing the gene involved in tryptophan biosynthesis, and a method of producing L-tryptophan using the same.
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3.发明申请GENETICALLY ENGINEERED RECOMBINANT ESCHERICHIA COLI PRODUCING L-TRYPTOPHAN HAVING ORIGINALLY L-PHENYLALANINE PRODUCTIVITY, AND METHOD FOR PRODUCING L-TRYPTOPHAN USING THE MICROORGANISM 有权具有原始L-苯丙氨酸生产力的基因工程重组蛋白生产L-酪氨酸的方法和使用微生物生产L-酪氨酸的方法公开(公告)号：US20120276639A1
公开(公告)日：2012-11-01
申请号：US13548044
申请日：2012-07-12
申请人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
发明人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
IPC分类号： C12N15/70
CPC分类号： C12P13/227 , C12N9/88 , C12N15/52
摘要： The present invention relates to a microorganism having L-tryptophan productivity and a method for producing L-tryptophan using the same. More precisely, the present invention relates to the recombinant E. coli strain CJ600 (KCCM 10812P) having tryptophan productivity produced from the mutant form (KFCC 10066) of E. coli having L-phenylalanine productivity, wherein tryptophan auxotrophy is released, L-phenylalanine biosynthesis is blocked but tryptophan productivity is enhanced by reinforcing the gene involved in tryptophan biosynthesis, and a method of producing L-tryptophan using the same.
摘要翻译： 本发明涉及具有L-色氨酸生产力的微生物和使用其的L-色氨酸的生产方法。 更准确地说，本发明涉及由具有L-苯丙氨酸生产力的大肠杆菌的突变形式（KFCC 10066）产生的具有色氨酸生产力的重组大肠杆菌菌株CJ600（KCCM 10812P），其中色氨酸营养缺陷型被释放，L-苯丙氨酸 生物合成被阻断，但通过加强色氨酸生物合成中涉及的基因来增强色氨酸的生产力，以及使用其生产L-色氨酸的方法。
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4.发明申请GENETICALLY ENGINEERED RECOMBINANT ESCHERICHIA COLI PRODUCING L-TRYPTOPHAN HAVING ORIGINALLY L-PHENYLALANINE PRODUCTIVITY, AND METHOD FOR PRODUCING L-TRYPTOPHAN USING THE MICROORGANISM 有权具有原始L-苯丙氨酸生产力的基因工程重组蛋白生产L-酪氨酸的方法和使用微生物生产L-酪氨酸的方法公开(公告)号：US20100028956A1
公开(公告)日：2010-02-04
申请号：US12520350
申请日：2007-12-28
申请人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
发明人： Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
CPC分类号： C12P13/227 , C12N9/88 , C12N15/52
摘要： The present invention relates to a microorganism having L-tryptophan productivity and a method for producing L-tryptophan using the same. More precisely, the present invention relates to the recombinant E. coli strain CJ600 (KCCM 10812P) having tryptophan productivity produced from the mutant form (KFCC 10066) of E. coli having L-phenylalanine productivity, wherein tryptophan auxotrophy is released, L-phenylalanine biosynthesis is blocked but tryptophan productivity is enhanced by reinforcing the gene involved in tryptophan biosynthesis, and a method of producing L-tryptophan using the same.
摘要翻译： 本发明涉及具有L-色氨酸生产力的微生物和使用其的L-色氨酸的生产方法。 更准确地说，本发明涉及由具有L-苯丙氨酸生产力的大肠杆菌的突变形式（KFCC 10066）产生的具有色氨酸生产力的重组大肠杆菌菌株CJ600（KCCM 10812P），其中色氨酸营养缺陷型被释放，L-苯丙氨酸 生物合成被阻断，但通过加强色氨酸生物合成中涉及的基因来增强色氨酸的生产力，以及使用其生产L-色氨酸的方法。
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