公开(公告)号：US20050113347A1

公开(公告)日：2005-05-26

申请号：US10342114

申请日：2003-01-14

申请人： Jagattaran Das ,  Selavakumar Natesan ,  Sanjay Trehan ,  Javed Iqbal ,  Sitaram Magadi ,  Naga Mamidi ,  Rajagopalan Ramanujam

发明人： Jagattaran Das ,  Selavakumar Natesan ,  Sanjay Trehan ,  Javed Iqbal ,  Sitaram Magadi ,  Naga Mamidi ,  Rajagopalan Ramanujam

IPC分类号： A61K31/4192 ,  A61K31/454 ,  A61K31/496 ,  A61K31/5355 ,  A61K31/5377 ,  A61K31/541 ,  A61K31/655 ,  A61P31/00 ,  A61P31/04 ,  C07D249/06 ,  C07D295/12 ,  C07D295/135 ,  C07D401/06 ,  C07D401/10 ,  C07D401/12 ,  C07D403/12 ,  C07D405/10 ,  C07D413/02 ,  C07D413/14 ,  C07D417/02 ,  C07D417/10 ,  C07D417/14 ,  C07D43/14

CPC分类号： C07D249/06 ,  C07D295/135 ,  C07D401/06 ,  C07D401/10 ,  C07D401/12 ,  C07D403/06 ,  C07D403/12 ,  C07D491/10

摘要： The present invention relates to novel triazole compounds of formula (I), their derivatives, their analogs, their tautomeric forms, their regioisomers, their rotamers, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them. More particularly, the present invention relates to novel triazoles of the general formula (I) their derivatives, their analogs, their tautomeric forms, their regioisomers, their rotamers, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them.

摘要翻译： 本发明涉及式（I）的新型三唑化合物，其衍生物，其类似物，其互变异构形式，其区域异构体，其旋转异构体，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂合物和含有它们的药物组合物 。 更具体地，本发明涉及通式（I）的新型三唑衍生物，其类似物，其互变异构体，其区域异构体，其旋转异构体，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂化物和药物 含有它们的组合物。

公开(公告)号：US20050209223A1

公开(公告)日：2005-09-22

申请号：US11120617

申请日：2005-05-03

申请人： Jagattaran Das ,  Selavakumar Natesan ,  Sanjay Trehan ,  Javed Iqbal ,  Sitaram Magadi ,  Naga Venkata Srinivasa Rao Mamidi ,  Rajagopalan Ramanujam

发明人： Jagattaran Das ,  Selavakumar Natesan ,  Sanjay Trehan ,  Javed Iqbal ,  Sitaram Magadi ,  Naga Venkata Srinivasa Rao Mamidi ,  Rajagopalan Ramanujam

IPC分类号： A61K31/4192 ,  A61K31/454 ,  A61K31/496 ,  A61K31/5355 ,  A61K31/5377 ,  A61K31/541 ,  A61K31/655 ,  A61P31/00 ,  A61P31/04 ,  C07D249/06 ,  C07D295/12 ,  C07D295/135 ,  C07D401/06 ,  C07D401/10 ,  C07D401/12 ,  C07D403/12 ,  C07D405/10 ,  C07D413/02 ,  C07D413/14 ,  C07D417/02 ,  C07D417/10 ,  C07D417/14

CPC分类号： C07D249/06 ,  C07D295/135 ,  C07D401/06 ,  C07D401/10 ,  C07D401/12 ,  C07D403/06 ,  C07D403/12 ,  C07D491/10

摘要： The present invention relates to novel triazole compounds of formula (I), their derivatives, their analogs, their tautomeric forms, their regioisomers, their rotamers, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them. More particularly, the present invention relates to novel triazoles of the general formula (I) their derivatives, their analogs, their tautomeric forms, their regioisomers, their rotamers, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them.

摘要翻译： 本发明涉及式（I）的新型三唑化合物，其衍生物，其类似物，其互变异构形式，其区域异构体，其旋转异构体，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂合物和含有它们的药物组合物 。 更具体地，本发明涉及通式（I）的新型三唑衍生物，其类似物，其互变异构体，其区域异构体，其旋转异构体，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂化物和药物 含有它们的组合物。

公开(公告)号：US06914058B2

公开(公告)日：2005-07-05

申请号：US10342114

申请日：2003-01-14

申请人： Jagattaran Das ,  Selavakumar Natesan ,  Sanjay Trehan ,  Javed Iqbal ,  Sitaram Kumar Magadi ,  Naga Venkata Srinivasa Rao Mamidi ,  Rajagopalan Ramanujam

发明人： Jagattaran Das ,  Selavakumar Natesan ,  Sanjay Trehan ,  Javed Iqbal ,  Sitaram Kumar Magadi ,  Naga Venkata Srinivasa Rao Mamidi ,  Rajagopalan Ramanujam

IPC分类号： A61K31/4192 ,  A61K31/454 ,  A61K31/496 ,  A61K31/5355 ,  A61K31/5377 ,  A61K31/541 ,  A61K31/655 ,  A61P31/00 ,  A61P31/04 ,  C07D249/06 ,  C07D295/12 ,  C07D295/135 ,  C07D401/06 ,  C07D401/10 ,  C07D401/12 ,  C07D403/12 ,  C07D405/10 ,  C07D413/02 ,  C07D413/14 ,  C07D417/02 ,  C07D417/10 ,  C07D417/14

CPC分类号： C07D249/06 ,  C07D295/135 ,  C07D401/06 ,  C07D401/10 ,  C07D401/12 ,  C07D403/06 ,  C07D403/12 ,  C07D491/10

摘要： The present invention relates to novel triazole compounds of formula (I), their derivatives, their analogs, their tautomeric forms, their regioisomers, their rotammers, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them. More particularly, the present invention relates to novel triazoles of the general formula (I) their derivatives, their analogs, their tautomeric forms, their regioisomers, their rotamers, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them.

摘要翻译： 本发明涉及式（I）的新型三唑化合物，其衍生物，其类似物，其互变异构形式，其区域异构体，其旋转异构体，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂合物和含有它们的药物组合物 。 更具体地，本发明涉及通式（I）的新型三唑衍生物，其类似物，其互变异构体，其区域异构体，其旋转异构体，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂化物和药物 含有它们的组合物。

公开(公告)号：US07202254B2

公开(公告)日：2007-04-10

申请号：US11120617

申请日：2005-05-03

申请人： Jagattaran Das ,  Selavakumar Natesan ,  Sanjay Trehan ,  Javed Iqbal ,  Sitaram Kumar Magadi ,  Naga Venkata Srinivasa Rao Mamidi ,  Rajagopalan Ramanujam

发明人： Jagattaran Das ,  Selavakumar Natesan ,  Sanjay Trehan ,  Javed Iqbal ,  Sitaram Kumar Magadi ,  Naga Venkata Srinivasa Rao Mamidi ,  Rajagopalan Ramanujam

IPC分类号： C07D401/10 ,  C07D401/14 ,  A61K31/4439 ,  A61P31/04

CPC分类号： C07D249/06 ,  C07D295/135 ,  C07D401/06 ,  C07D401/10 ,  C07D401/12 ,  C07D403/06 ,  C07D403/12 ,  C07D491/10

摘要： The present invention relates to novel triazole compounds of formula (I), their derivatives, their analogs, their tautomeric forms, their regioisomers, their rotamers, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them. More particularly, the present invention relates to novel triazoles of the general formula (I) their derivatives, their analogs, their tautomeric forms, their regioisomers, their rotamers, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them.

摘要翻译： 本发明涉及式（I）的新型三唑化合物，其衍生物，其类似物，其互变异构形式，其区域异构体，其旋转异构体，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂合物和含有它们的药物组合物 。 更具体地说，本发明涉及通式（I）的新型三唑，

公开(公告)号：US20060270628A1

公开(公告)日：2006-11-30

申请号：US10554472

申请日：2004-04-29

申请人： Jagattaran Das ,  Selvakumar Natesan ,  Sanjay Trehan ,  Javed Iqbal ,  Sitaram Magadi

发明人： Jagattaran Das ,  Selvakumar Natesan ,  Sanjay Trehan ,  Javed Iqbal ,  Sitaram Magadi

IPC分类号： A61K31/695 ,  A61K31/655 ,  A61K31/4192 ,  C07D403/02 ,  C07F7/02

CPC分类号： C07D403/10

摘要： The present invention relates to novel triazole compounds of formula (I), thie pharmaceutically acceptable salts and their pharmaceutical compositions, where all symbols have meaning as defined in the description, for use in the treatment of bacterial infections.

摘要翻译： 本发明涉及式（I）的新型三唑化合物，其药学上可接受的盐及其药物组合物，其中所有符号具有如说明书中定义的含义，用于治疗细菌感染。

公开(公告)号：US07183301B2

公开(公告)日：2007-02-27

申请号：US10632950

申请日：2003-08-01

申请人： Selvakumar Natesan ,  Jagattaran Das ,  Javed Iqbal ,  Sitaram Kumar Magadi ,  Srinivasa Rao Naga Venkata Mamidi ,  Rajagopalan Ramanujam ,  Baskaran Sundarababu ,  Braj Bhushan Lohray

发明人： Selvakumar Natesan ,  Jagattaran Das ,  Javed Iqbal ,  Sitaram Kumar Magadi ,  Srinivasa Rao Naga Venkata Mamidi ,  Rajagopalan Ramanujam ,  Baskaran Sundarababu ,  Braj Bhushan Lohray

IPC分类号： A61K31/427 ,  C07C277/04

CPC分类号： C07D263/20 ,  C07D263/22 ,  C07D263/24 ,  C07D413/10 ,  C07D413/14 ,  C07D417/10

摘要： The present invention relates to novel oxazolidinone compounds of the general formula (I). where R1, R2, R3, Y1, Y2, Y3, and Z are as defined in the description; their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them.

摘要翻译： 本发明涉及通式（I）的新型恶唑烷酮化合物。 其中R 1，R 2，R 3，Y 1，Y 2， Y 3和Z如说明书中所定义; 它们的衍生物，它们的类似物，它们的互变异构形式，它们的立体异构体，它们的多晶型物，其药学上可接受的盐，它们的药学上可接受的溶剂化物和含有它们的药物组合物。

公开(公告)号：US20070004712A1

公开(公告)日：2007-01-04

申请号：US11511799

申请日：2006-08-29

申请人： Natesan Selvakumar ,  Jagattaran Das ,  Sanjay Trehan ,  Javed Iqbal ,  Magadi Kumar ,  Ramanujam Rajagopalan ,  Mamidi Naga Rao

发明人： Natesan Selvakumar ,  Jagattaran Das ,  Sanjay Trehan ,  Javed Iqbal ,  Magadi Kumar ,  Ramanujam Rajagopalan ,  Mamidi Naga Rao

IPC分类号： A61K31/541 ,  A61K31/427 ,  A61K31/422 ,  C07D417/14 ,  C07D417/02 ,  C07D413/02

CPC分类号： C07D263/20 ,  C07D413/10 ,  C07D413/14 ,  C07D417/14

摘要： The present invention relates to novel oxazolidinone compounds of formula (I), their stereoisomers, their salts and pharmaceutical compositions containing them. The present invention also relates to a process for the preparation of the above said novel compounds, their stereoisomers, their salts and pharmaceutical compositions.

摘要翻译： 本发明涉及式（I）的新型恶唑烷酮化合物，其立体异构体，其盐和含有它们的药物组合物。 本发明还涉及制备上述新化合物，其立体异构体，其盐和药物组合物的方法。

公开(公告)号：US07160912B2

公开(公告)日：2007-01-09

申请号：US10613414

申请日：2003-07-03

申请人： Natesan Selvakumar ,  Jagattaran Das ,  Sanjay Trehan ,  Javed Iqbal ,  Magadi Sitaram Kumar ,  Ramanujam Rajagopalan ,  Mamidi Naga Venkata Srinivasa Rao

发明人： Natesan Selvakumar ,  Jagattaran Das ,  Sanjay Trehan ,  Javed Iqbal ,  Magadi Sitaram Kumar ,  Ramanujam Rajagopalan ,  Mamidi Naga Venkata Srinivasa Rao

IPC分类号： A61K31/421 ,  C07D263/04 ,  C07D413/12

CPC分类号： C07D263/20 ,  C07D263/22 ,  C07D263/24 ,  C07D413/10 ,  C07D413/14 ,  C07D417/10

摘要： The present invention relates to novel oxazolidinone compounds of formula (I), their stereoisomers, their salts and pharmaceutical compositions containing them. The present invention also relates to a process for the preparation of the above said novel compounds, their stereoisomers, their salts and pharmaceutical compositions.

摘要翻译： 本发明涉及式（I）的新型恶唑烷酮化合物，其立体异构体，其盐和含有它们的药物组合物。 本发明还涉及制备上述新化合物，其立体异构体，其盐和药物组合物的方法。

公开(公告)号：US20060293315A1

公开(公告)日：2006-12-28

申请号：US11511756

申请日：2006-08-29

申请人： Natesan Selvakumar ,  Jagattaran Das ,  Sanjay Trehan ,  Javed Iqbal ,  Magadi Kumar ,  Ramanujam Rajagopalan ,  Mamidi Naga Rao

发明人： Natesan Selvakumar ,  Jagattaran Das ,  Sanjay Trehan ,  Javed Iqbal ,  Magadi Kumar ,  Ramanujam Rajagopalan ,  Mamidi Naga Rao

IPC分类号： A61K31/541 ,  A61K31/423 ,  A61K31/427 ,  C07D417/02 ,  C07D413/02

CPC分类号： C07D263/20 ,  C07D413/10 ,  C07D413/14 ,  C07D417/14

摘要： The present invention relates to novel oxazolidinone compounds of formula (I), their stereoisomers, their salts and pharmaceutical compositions containing them. The present invention also relates to a process for the preparation of the above said novel compounds, their stereoisomers, their salts and pharmaceutical compositions.

摘要翻译： 本发明涉及式（I）的新型恶唑烷酮化合物，其立体异构体，其盐和含有它们的药物组合物。 本发明还涉及制备上述新化合物，其立体异构体，其盐和药物组合物的方法。

公开(公告)号：US07030148B2

公开(公告)日：2006-04-18

申请号：US10032392

申请日：2001-12-21

申请人： Selvakumar Natesan ,  Jagattaran Das ,  Javed Iqbal ,  Sitaram Kumar Magadi ,  Srinivasa Rao Naga Venkata Mamidi ,  Rajagopalan Ramanujam ,  Baskaran Sundarababu ,  Braj Bhushan Lohray

发明人： Selvakumar Natesan ,  Jagattaran Das ,  Javed Iqbal ,  Sitaram Kumar Magadi ,  Srinivasa Rao Naga Venkata Mamidi ,  Rajagopalan Ramanujam ,  Baskaran Sundarababu ,  Braj Bhushan Lohray

IPC分类号： A61K31/421 ,  C07D263/04

CPC分类号： C07D263/20 ,  C07D263/22 ,  C07D263/24 ,  C07D413/10 ,  C07D413/14 ,  C07D417/10

摘要： The present invention relates to novel oxazolidinone compounds of the general formula (I) where R1, R2, R3, Y1, Y2, Y3, and Z are as defined in the description; their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutical acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them.

摘要翻译： 本发明涉及通式（I）的新的恶唑烷酮化合物，其中R 1，R 2，R 3，Y 3， 1，Y 2，Y 3，Z如说明书中所定义; 它们的衍生物，它们的类似物，它们的互变异构形式，它们的立体异构体，它们的多晶型物，它们的药学上可接受的盐，它们的药学上可接受的溶剂合物和含有它们的药物组合物。