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公开(公告)号：US5938032A
公开(公告)日：1999-08-17
申请号：US826398
申请日：1997-03-24
CPC分类号： B65D75/5816 , B65B9/02 , B65D75/30
摘要： A system of the present invention includes a tandem package and an apparatus and method for making the same. The tandem package includes a strip of film material having a plurality of medicament containing compartments. To prevent ripping or exposure of the medicament in an adjacent compartment upon opening of an individual segment of the package, each compartment is separated by a dividing member. In addition, to facilitate opening of the each segment while providing increased resistance to opening by children, each segment includes a pinhole in at least one corner of the segment perpendicular to a fold line. Thus to open the segment to expose the medicament, the corner may be folded along the fold line and torn at the pinhole, with the dividing member limiting tearing of the film. The apparatus and method of the present invention include a number of sub-assemblies for sealing the film, forming the compartments, placing the dividing member between the compartments, placing the dose of medicament in each compartment and cutting the continuous web into strips having the desired number of segments therein.
摘要翻译： 本发明的系统包括串联封装及其制造方法。 串联包装包括具有多个药物容纳隔室的薄膜材料条。 为了防止在打开包装件的单独部分时相邻隔室中的药物的撕裂或暴露，每个隔室由分隔构件分开。 此外，为了便于每个片段的打开，同时提供增加的对儿童打开的阻力，每个片段在垂直于折叠线的片段的至少一个角落中包括针孔。 因此为了打开该区段以露出药物，角部可以沿折叠线折叠并在针孔处撕开，分隔构件限制膜的撕裂。 本发明的装置和方法包括许多用于密封薄膜的子组件，形成隔室，将分隔构件放置在隔室之间，将药物的剂量放置在每个隔室中，并将连续腹板切割成具有期望的条带 其中的段数。
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公开(公告)号：US5472093A
公开(公告)日：1995-12-05
申请号：US129626
申请日：1993-09-30
CPC分类号： B65D75/30 , B65B9/02 , B65D75/5816
摘要： A system of the present invention includes a tandem package and an apparatus and method for making the same. The tandem package includes a strip of film material having a plurality of medicament containing compartments. To prevent ripping or exposure of the medicament in an adjacent compartment upon opening of an individual segment of the package, each compartment is separated by a dividing member. In addition, to facilitate opening of the each segment while providing increased resistance to opening by children, each segment includes a tear notch in at least one corner of the segment perpendicular to a fold line. Thus to open the segment to expose the medicament, the corner my be folded along the fold line and torn at tear notch, with the dividing member limiting tearing of the film. The apparatus and method of the present invention include a number of sub-assemblies for sealing the film, forming the compartments, placing the dividing member between the compartments, placing the dose of medicament in each compartment and cutting the continuous web into strips having the desired number of segments therein.
摘要翻译： 本发明的系统包括串联封装及其制造方法。 串联包装包括具有多个药物容纳隔室的薄膜材料条。 为了防止在打开包装件的单独部分时相邻隔室中的药物的撕裂或暴露，每个隔室由分隔构件分开。 此外，为了便于每个片段的打开，同时提供增加的对儿童打开的阻力，每个片段在垂直于折叠线的片段的至少一个角部中包括撕裂缺口。 因此为了打开该部分以暴露药物，拐角我的折叠线折叠并撕裂在撕裂口处，分隔部件限制了胶片的撕裂。 本发明的装置和方法包括许多用于密封薄膜的子组件，形成隔室，将分隔构件放置在隔室之间，将药物的剂量放置在每个隔室中，并将连续腹板切割成具有期望的条带 其中的段数。
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公开(公告)号：US5000804A
公开(公告)日：1991-03-19
申请号：US287774
申请日：1988-12-21
申请人： Edward L. Nugent
发明人： Edward L. Nugent
CPC分类号： B01L3/5082 , A61B5/15003 , A61B5/150351 , A61B5/153 , A61B5/154 , G01N2001/007
摘要： A composite body fluid sample container is provided which incorporates safety features for containing diseased samples of such fluids from touching and/or contaminating anyone handling the samples. The composite includes a glass sample container, either evacuated or not, depending upon use which has disposed thereon a "shrunk down" sleeve of a thermoplastic film. In the event that the glass is cracked or broken, the sleeve holds the sample from spilling or leaking onto the hands of a person handling the container, or otherwise spreading a diseased sample by spilling, leakage, or cutting by broken glass.
摘要翻译： 提供了一种复合体液样品容器，其包含用于容纳患有这种流体的患病样品的操作样本的任何人的接触和/或污染的安全特征。 复合材料包括玻璃样品容器，根据其中已经在其上放置有热塑性薄膜的“收缩”套筒的用途，该容器被抽真空。 在玻璃破裂或破裂的情况下，套筒将样品悬浮或泄漏到操作容器的人的手上，或者以破碎的玻璃溢出，泄漏或切割散布患病样品。
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公开(公告)号：US4140108A
公开(公告)日：1979-02-20
申请号：US823415
申请日：1977-08-10
申请人： Edward L. Nugent
发明人： Edward L. Nugent
CPC分类号： A61B5/15003 , A61B5/150221 , A61B5/150351 , A61B5/150389 , A61B5/150519 , A61B5/150572 , A61B5/150732 , A61B5/150992 , A61B5/154
摘要： The disclosure is of an assembly for the collection of blood from a mammalian blood vessel. The assembly comprises a flexible tube having needle cannulas mounted on each end. One of the needle cannulas is threadably secured to a holder member for holding a blood collection container. The assembly of the invention makes possible blood sampling regardless of the orientation of the mammal from whom the blood is being collected.
摘要翻译： 本公开是用于从哺乳动物血管收集血液的组件。 组件包括一个具有安装在每个端部上的针插管的柔性管。 针插管中的一个螺纹地固定到用于保持采血容器的保持器构件。 本发明的组合使得可以进行血液采样，而不管收集血液的哺乳动物的取向如何。
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公开(公告)号：US4620549A
公开(公告)日：1986-11-04
申请号：US695121
申请日：1985-01-25
申请人： Edward L. Nugent
发明人： Edward L. Nugent
CPC分类号： B01L3/50825
摘要： A blood microcollection container and associated collection assembly is provided for engaging a puncture wound and rapidly receiving blood from the wound. The assembly incorporates a scoop arrangement for engaging the blood source, and for directing in a rapid and efficient manner the blood to a collection chamber. A two-position cap is provided for sealing the scoop collector of the assembly prior to use, and for permanently locking to the collector after use to prevent exposure to the blood sample by the person handling the blood sample, or contamination of the blood sample from outside sources.
摘要翻译： 提供血液收集容器和相关联的收集组件用于接合穿刺伤口并快速接收来自伤口的血液。 组合件包括用于接合血液源的勺子装置，并且用于以快速且有效的方式将血液引导到收集室。 提供两位置盖用于在使用之前密封组件的勺子收集器，并且在使用之后永久性地锁定到收集器，以防止处理血液样本的人暴露于血液样品，或者从 外部来源。
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公开(公告)号：US4398544A
公开(公告)日：1983-08-16
申请号：US311494
申请日：1981-10-15
申请人： Edward L. Nugent , Joseph Kaufman
发明人： Edward L. Nugent , Joseph Kaufman
CPC分类号： A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150259 , A61B5/150351 , A61B5/150404 , A61B5/150511 , A61B5/150519 , A61B5/150572 , A61B5/150702 , A61B5/150732 , A61B5/1545 , A61B5/155
摘要： A single or multiple liquid sample needle assembly is provided. The assembly includes a housing with a receiving chamber having translucent or transparent walls for determining whether access to the sample in question has been achieved. The invention utilizes a porous plug in the chamber which provides, simultaneously, a liquid barrier for the sample received, and gas displacement venting means for gas displaced by the liquid sample received. The assembly may be modified to receive only a single sample for subsequent discharge to a vacuum collection device, or multiple samples for sequential discharge to a plurality of vacuum collection devices. For multiple collection, the assembly incorporates a flexible sleeve and a separate gas discharge opening in combination with the sample discharge opening of the assembly.
摘要翻译： 提供单个或多个液体样品针组件。 组件包括具有接收室的壳体，该容纳室具有半透明或透明壁，用于确定是否已经获得对所述样品的存取。 本发明利用了腔室中的多孔塞子，同时提供了所接收的样品的液体阻挡层，以及由接收的液体样品置换的气体的气体排放通气装置。 组件可以被修改为仅接收单个样品用于随后排放到真空收集装置，或者多个样品用于顺序排放到多个真空收集装置。 对于多次收集，组件包括柔性套管和与组件的样品排出开口组合的单独的气体排出口。
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公开(公告)号：US4449529A
公开(公告)日：1984-05-22
申请号：US322345
申请日：1981-11-18
申请人： James A. Burns , Edward L. Nugent
发明人： James A. Burns , Edward L. Nugent
CPC分类号： A61B5/150022 , A61B5/150152 , A61B5/150297 , A61B5/150435 , A61B5/150916 , A61B5/15113 , A61B5/15117 , A61B5/1513 , A61B5/15142 , A61B5/15144
摘要： An automatic retractable lancet assembly includes a housing with a sharp-pointed lancet movably mounted therein. A slidable plunger is mounted in the housing in the end thereof opposite from the lancet for loading the assembly prior to use. An actuating mechanism releases the lancet for outward movement from the housing. After this outward movement is completed, the actuator elements become dissociated from further movement of the lancet. Subsequently, the lancet is automatically retracted back inside the housing by virtue of a spring element.
摘要翻译： 一种自动伸缩式柳叶刀组件，其包括具有可移动地安装在其中的尖锐刺血针的壳体。 可滑动的柱塞安装在壳体的与柳叶刀相对的端部，用于在使用之前加载组件。 致动机构释放刺血针以从外壳向外运动。 在该向外移动完成之后，致动器元件与柳叶刀的进一步移动分离。 随后，借助于弹簧元件，柳叶刀自动地缩回到壳体内部。
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公开(公告)号：US4134512A
公开(公告)日：1979-01-16
申请号：US804502
申请日：1977-06-08
申请人： Edward L. Nugent
发明人： Edward L. Nugent
CPC分类号： B01L3/50825 , A61B5/15003 , A61B5/150221 , A61B5/150251 , A61B5/150351 , A61B5/150389 , A61B5/150496 , A61B5/150755 , A61B5/154
摘要： Stopper for an evacuated tube with an open end for collecting fluid such as blood samples. The stopper includes a plug adapted to be mounted in the opening in the tube so as to normally seal the tube. The plug permits access of a fluid sample needle therethrough into fluid communication with the reduced pressure interior of the tube so that fluid is collected in the tube from the needle. A check valve is on the plug to automatically open when the needle is inserted through the plug and subjected to the reduced pressure in the tube and to automatically close when subjected to a predetermined amount of pressure from within the tube such as that caused by backflow thereby preventing any fluid passing into the needle from the tube. The check valve includes a chamber which can be used as a reagent holder prior to the tube use.
摘要翻译： 具有开口端的真空管的塞子用于收集诸如血液样品的液体。 止动器包括适于安装在管中的开口中以便正常密封管的塞子。 插头允许流体样本针通过其与管的减压内部流体连通，使得流体从针收集在管中。 当针插入插头并经受管中的减压时，止动阀在插头上自动打开，并在受到来自管内的预定量的压力（例如由回流引起的压力）时自动关闭 防止从管中进入针的任何流体。 止回阀包括可以在管使用之前用作试剂保持器的腔室。
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公开(公告)号：US4071319A
公开(公告)日：1978-01-31
申请号：US745101
申请日：1976-11-26
申请人： Edward L. Nugent
发明人： Edward L. Nugent
CPC分类号： B01L3/5082 , G01N31/22 , G01N33/0027
摘要： Apparatus for the detection of contaminants in fluids. In the simplest embodiment, the apparatus comprises a vacuum tube having indicator means disposed therein for the detection of a fluid-borne contaminant and a self-sealing, cannula-penetrable closure. The apparatus is operated by piercing the closure with a cannula to draw the fluid for testing into the vacuum chamber.
摘要翻译： 用于检测流体中污染物的装置。 在最简单的实施例中，该装置包括真空管，其具有设置在其中的指示器装置，用于检测流体传播的污染物和自密封插管可穿透的封闭件。 该装置通过用套管刺穿闭合件来操作，以将流体抽吸以用于测试进入真空室。
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公开(公告)号：US4417981A
公开(公告)日：1983-11-29
申请号：US260530
申请日：1981-05-04
申请人： Edward L. Nugent
发明人： Edward L. Nugent
CPC分类号： B01L3/50215 , G01N33/491
摘要： A blood collection device for receiving whole blood adapted to be centrifuged into phases of lighter and heavier specific gravity includes a container with proximal and distal ends and a penetrable stopper at the proximal end. A separator assembly inside the container includes a receptacle with a thixotropic barrier material therein. An aperture in the receptacle faces toward the distal end of the container. The barrier material has a specific gravity intermediate the specific gravities of the lighter and heavier phases of blood and is adapted to flow under its own influence through the aperture during centrifugation. The barrier material then travels to a position intermediate the lighter and heavier phases of blood separated during centrifugation and adheres to the inside wall of the container to form a barrier.
摘要翻译： 用于接收全部血液的血液采集装置，该全血适于被分离成更轻和更重的比重的相，包括具有近端和远端的容器和在近端的可穿透塞子。 容器内的分离器组件包括其中具有触变阻挡材料的容器。 容器中的孔朝向容器的远端。 阻隔材料的比重介于较轻和较重的血液相位的比重，并且适于在离心过程中通过孔径在其自身的影响下流动。 然后阻挡材料行进到在离心过程中分离的较轻和较重的血液相之间的位置，并粘附到容器的内壁以形成屏障。
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