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公开(公告)号：US20220265564A1
公开(公告)日：2022-08-25
申请号：US17675931
申请日：2022-02-18
IPC分类号： A61K9/50
摘要： A lipid capsid comprising at least one S type protein for attachment to the ACE2 receptor of a cancer cell is provided. The lipid capsid encloses an inner package, comprising histone or a histone eviction compound. The S type protein of the lipid capsid attaches to the ACE2 receptor of a targeted cancer cell, enabling the outer lipid envelope of the capsid to be absorbed through the cell wall of the targeted cell, after which the inner package of the lipid capsid is delivered to the cancer cell. In some embodiments, the histone is selected from the H2AX histone, the H3K27 histone or the H3K9 histone, each histone having a different mechanism of action to disable the cancer cell or repair the DNA of the cancer cell. In another embodiment, the inner package contains a histone eviction compound for evicting histone from the cancer cell.
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公开(公告)号：US09429018B2
公开(公告)日：2016-08-30
申请号：US13514912
申请日：2010-12-08
CPC分类号： F01B23/10 , F24D5/04 , F24D11/0214 , F24D11/0285 , F24D2200/19 , F24D2200/26 , F24H7/00 , F24H2240/06 , F24H2240/10 , F28D1/0472 , F28D20/0034 , F28D20/0056 , F28D20/026 , F28D21/0003 , F28D2020/0078 , F28D2020/0082 , H02K7/1815 , Y02B10/70 , Y02B30/125 , Y02B30/52 , Y02E20/14 , Y02E60/142 , Y02E60/145
摘要： Synergistic Energy Ecosystem using a co-generation system and method wherein waste energy from waste heat producers within an enclosure including an electric generator is reclaimed to supply heat to the cold end of a heat pump within the enclosure for optimized use in space heating a habitat and to the management of the distribution of electricity from the generator so as to supply electricity to the habitat and to neighboring habitats when efficient, cost-effective or required to do so by distribution policies managing the energy eco-system.
摘要翻译： 协同能源生态系统使用共同生成系统和方法，其中包括发电机的外壳内的废热源的废能源被回收以向外壳内的热泵的冷端供热，以优化在空间中加热栖息地， 管理电力发电机的电力管理，以便通过管理能源生态系统的分配政策，在有效率，成本效益或需要这样做的情况下，向栖息地和相邻生境供电。
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公开(公告)号：US09316213B2
公开(公告)日：2016-04-19
申请号：US14025661
申请日：2013-09-12
IPC分类号： F03H1/00
CPC分类号： F03H1/0018 , F03H1/0006 , F03H1/0012 , F03H1/0081 , F03H1/0087 , F05D2220/80
摘要： A plasma drive includes a plurality of plasma thrusters arrayed in each of at least one array of plasma thrusters. Plasma thrust may be generated sequentially or in a pulse from each array. Circuitry is adapted to selectively fire each thruster in each array according to a digitally controlled progression. The controlled firing progression collectively provides a cumulative thrust vector for each array. In a turbine drive embodiment the controlled progression causes sequential firing of the thrusters in each array, and the arrays in sequence. The controlled progression allows for directional control of the combined cumulative thrust vectors.
摘要翻译： 等离子体驱动器包括排列在等离子体推进器的至少一个阵列中的每一个中的多个等离子体推进器。 等离子推力可以顺序地或以每个阵列的脉冲产生。 电路适合于根据数字控制的进程选择性地对每个阵列中的每个推进器进行点火。 受控发射进程集中地为每个阵列提供累积推力矢量。 在涡轮机驱动实施例中，受控进展导致每个阵列中的推进器的顺序点火，以及顺序上的阵列。 受控进度允许组合累积推力矢量的方向控制。
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公开(公告)号：US20220342119A1
公开(公告)日：2022-10-27
申请号：US17727023
申请日：2022-04-22
摘要： Metamaterial devices for optical absorption, dispersion and directional sensing include optically transparent prisms made of a wide range optically transparent material, the prisms comprising a lens surface that is exposed to a source of electromagnetic radiation, with the other surfaces of the prism adjacent to a sensing device, a reflective surface and/or an optical absorption surface. Absorption devices are configured to trap and absorb the electromagnetic radiation that enters the lens surface. Dispersion devices are configured to scatter the electromagnetic radiation that enters the lens surface and the infrared radiation that radiates from an object and through the prism towards the lens surface. The directional sensing devices are configured to selectively detect electromagnetic radiation entering the device at a target angle.
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公开(公告)号：US09771383B2
公开(公告)日：2017-09-26
申请号：US14710777
申请日：2015-05-13
IPC分类号： C07F7/10 , C01B21/092 , A61K31/695 , C07F7/18 , C07F7/21 , C07F7/08
CPC分类号： C07F7/10 , A61K31/695 , C01B21/092 , C07F7/0801 , C07F7/1804 , C07F7/1872 , C07F7/21
摘要： A modified opioid is provided comprising modified morphine molecules, wherein for each morphine molecule, one or more carbon atoms are replaced with silicon atoms. A method is further provided for modifying an opioid comprising morphine molecules, said method comprising the step of replacing one or more carbon atoms with silicon atoms.
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公开(公告)号：US09316726B2
公开(公告)日：2016-04-19
申请号：US13720674
申请日：2012-12-19
CPC分类号： G01S13/04 , G01S2013/029
摘要： A quantum harmonic radar method includes comparing the determined timing or spacing of the detected hertzian waves with the pre-determined amplitude and frequency of the hertzian waves being transmitted from a transmitter, and by the comparison determining if the detected hertzian waves have a spacing therebetween is greater than a spacing between said transmitted hertzian waves having said pre-determined amplitude and frequency, whereupon signalling a presence in said transmission field of an electromagnetic energy absorbent object.
摘要翻译： 量子谐波雷达方法包括将所检测的赫兹波的确定的定时或间隔与从发射机发送的赫兹波的预定幅度和频率进行比较，并且通过比较来确定检测到的赫兹波是否具有间隔， 大于具有所述预定幅度和频率的所述传输的赫兹波之间的间隔，从而发信号通知电磁能吸收物体的所述传输场中的存在。
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公开(公告)号：US20130076033A1
公开(公告)日：2013-03-28
申请号：US13514912
申请日：2010-12-08
IPC分类号： F01B23/10
CPC分类号： F01B23/10 , F24D5/04 , F24D11/0214 , F24D11/0285 , F24D2200/19 , F24D2200/26 , F24H7/00 , F24H2240/06 , F24H2240/10 , F28D1/0472 , F28D20/0034 , F28D20/0056 , F28D20/026 , F28D21/0003 , F28D2020/0078 , F28D2020/0082 , H02K7/1815 , Y02B10/70 , Y02B30/125 , Y02B30/52 , Y02E20/14 , Y02E60/142 , Y02E60/145
摘要： Synergistic Energy Ecosystem using a co-generation system and method wherein waste energy from waste heat producers within an enclosure including an electric generator is reclaimed to supply heat to the cold end of a heat pump within the enclosure for optimized use in space heating a habitat and to the management of the distribution of electricity from the generator so as to supply electricity to the habitat and to neighbouring habitats when efficient, cost-effective or required to do so by distribution policies managing the energy eco-system.
摘要翻译： 协同能源生态系统使用共同生成系统和方法，其中包括发电机的外壳内的废热源的废能源被回收以向外壳内的热泵的冷端供热，以优化在空间中加热栖息地， 管理电力发电机的电力管理，以便通过管理能源生态系统的分配政策，在有效率，成本效益或需要这样做的情况下，向栖息地和相邻生境供电。
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公开(公告)号：US20210195726A1
公开(公告)日：2021-06-24
申请号：US17117447
申请日：2020-12-10
摘要： A linear accelerator comprises a plurality of cyclotrons arranged axially in a cyclotron stack, each cyclotron having a set of dees and a central aperture passing through the set of dees. Each central aperture is axially aligned with one another in the stack, forming a central channel having an inlet and an outlet that passes through the stack. Magnets are positioned so as to generate a magnetic field perpendicular to the set of dees. A power supply applies an oscillating voltage to each set of dees of the stack. In operation, subatomic particles are ejected radially outwardly of the stack, creating a dead zone within the central channel that is void of particles and electromagnetic fields. A mass or light beam is accelerated as it passes through the central channel's dead zone, due to the absence of frictional forces acting on the mass or light within the dead zone.
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公开(公告)号：US20160362430A1
公开(公告)日：2016-12-15
申请号：US14710777
申请日：2015-05-13
IPC分类号： C07F7/10 , C07F7/08 , C01B21/092 , C07F7/18
CPC分类号： C07F7/10 , A61K31/695 , C01B21/092 , C07F7/0801 , C07F7/1804 , C07F7/1872 , C07F7/21
摘要： A modified opioid is provided comprising modified morphine molecules, wherein for each morphine molecule, one or more carbon atoms are replaced with silicon atoms. A method is further provided for modifying an opioid comprising morphine molecules, said method comprising the step of replacing one or more carbon atoms with silicon atoms.
摘要翻译： 提供了修饰的阿片样物质，其包含修饰的吗啡分子，其中对于每个吗啡分子，一个或多个碳原子被硅原子替代。 还提供了一种用于修饰包含吗啡分子的阿片样物质的方法，所述方法包括用硅原子置换一个或多个碳原子的步骤。
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公开(公告)号：US20160032906A1
公开(公告)日：2016-02-04
申请号：US14025661
申请日：2013-09-12
IPC分类号： F03H1/00
CPC分类号： F03H1/0018 , F03H1/0006 , F03H1/0012 , F03H1/0081 , F03H1/0087 , F05D2220/80
摘要： A plasma drive includes a plurality of plasma thrusters arrayed in each of at least one array of plasma thrusters. Plasma thrust may be generated sequentially or in a pulse from each array. Circuitry is adapted to selectively fire each thruster in each array according to a digitally controlled progression. The controlled firing progression collectively provides a cumulative thrust vector for each array. In a turbine drive embodiment the controlled progression causes sequential firing of the thrusters in each array, and the arrays in sequence. The controlled progression allows for directional control of the combined cumulative thrust vectors.
摘要翻译： 等离子体驱动器包括排列在等离子体推进器的至少一个阵列中的每一个中的多个等离子体推进器。 等离子推力可以顺序地或以每个阵列的脉冲产生。 电路适合于根据数字控制的进程选择性地对每个阵列中的每个推进器进行点火。 受控发射进程集中地为每个阵列提供累积推力矢量。 在涡轮机驱动实施例中，受控进展导致每个阵列中的推进器的顺序点火，以及顺序地排列阵列。 受控进度允许组合累积推力矢量的方向控制。
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