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公开(公告)号:US20050272028A1
公开(公告)日:2005-12-08
申请号:US11190767
申请日:2005-07-25
申请人: James Bass , Carole Berry , Ravi Kambadur , Mridula Sharma , Mark Thomas
发明人: James Bass , Carole Berry , Ravi Kambadur , Mridula Sharma , Mark Thomas
CPC分类号: C07K14/475 , A61K38/00
摘要: An isolated mimetic of functional myostatin comprising part of the amino acid sequence of functional myostatin, such that the mimetic is capable of inhibiting muscle growth.
摘要翻译: 功能性肌生成抑制素的分离模拟物,其包含功能性肌生成抑制素的氨基酸序列的一部分,使得模拟物能够抑制肌肉生长。
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公开(公告)号:US20080051328A1
公开(公告)日:2008-02-28
申请号:US10580901
申请日:2004-11-26
申请人: Mridula Sharma , Carole Berry , Mark Thomas , Ravi Kambadur , Robert Bower
发明人: Mridula Sharma , Carole Berry , Mark Thomas , Ravi Kambadur , Robert Bower
IPC分类号: A61K38/17 , A01K67/027 , C07K14/435 , C12N15/11 , C12N15/86 , G01N33/53 , C12Q1/68 , C12N15/85 , C07K16/18 , A61K31/7088
CPC分类号: C07K14/475 , A61K38/00 , C07K16/18 , C12Q1/6883 , C12Q2600/124 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158
摘要: A muscle growth regulating factor includes polynucleotide and polypeptide sequences, promoter sequences, constructs comprising the sequences, and compositions for regulating muscle growth and treating diseases associated with muscle growth. The present sequences can be used in identifying animals with altered muscle mass, and for selective breeding programs to produce animals with altered muscle mass.
摘要翻译: 肌肉生长调节因子包括多核苷酸和多肽序列,启动子序列,包含该序列的构建体和用于调节肌肉生长和治疗与肌肉生长有关的疾病的组合物。 本发明的序列可用于鉴定具有改变的肌肉质量的动物,以及用于选择育种程序以产生具有改变的肌肉质量的动物。
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