公开(公告)号：US5908442A

公开(公告)日：1999-06-01

申请号：US837245

申请日：1997-04-10

申请人： James E. Brewer ,  Gary B. Stendahl

发明人： James E. Brewer ,  Gary B. Stendahl

IPC分类号： A61N1/39

CPC分类号： A61N1/39 ,  A61N1/3906 ,  A61N1/3912 ,  A61N1/3925

摘要： A method and apparatus for delivering a stepped truncated damped sinusoidal external defibrillation waveform which, when applied through a plurality of electrodes positioned on a patient's torso will produce a desired response in the patient's cardiac cell membranes is provided. Further, the method and apparatus sufficiently approximates a constant current defibrillation shock pulse. The method includes the steps monitoring a patient-dependent electrical parameter and determining a duration based on the parameter determined. First and second charge storage components are then charged. A first truncating switch is then closed to discharge the first charge storage component. After a predetermined delay, a second truncating switch is closed to discharge the second charge storage component. Then, after the duration period that was calculated has expired the switches are opened to truncate the waveform. The computation of discharge duration is made as a function of the desired cardiac membrane response function, a patient model and a defibrillator circuit model.

摘要翻译： 提供了一种用于递送阶梯式截短阻尼正弦外部除颤波形的方法和装置，当通过位于患者躯干上的多个电极施加时，将产生在患者的心脏细胞膜中的期望的响应。 此外，该方法和装置充分接近恒流除颤冲击脉冲。 该方法包括监视与患者相关的电参数并基于确定的参数来确定持续时间的步骤。 然后对第一和第二电荷存储部件进行充电。 然后关闭第一截断开关以排出第一电荷存储部件。 在预定的延迟之后，关闭第二截断开关以排出第二电荷存储部件。 然后，在计算的持续时间段到期之后，开关被打开以截断波形。 放电持续时间的计算作为所需心脏膜响应函数，患者模型和除颤器电路模型的函数。

公开(公告)号：US5978706A

公开(公告)日：1999-11-02

申请号：US158236

申请日：1998-09-22

申请人： James E. Brewer ,  Gary B. Stendahl

发明人： James E. Brewer ,  Gary B. Stendahl

IPC分类号： A61N1/39

CPC分类号： A61N1/39 ,  A61N1/3906 ,  A61N1/3912 ,  A61N1/3925

摘要： An apparatus for generating a waveform for use in externally defibrillating the heart of a patient includes a plurality of capacitors chargeable to respective charge potentials. A control apparatus is operatively coupled with the capacitors to sequentially interconnect the capacitors in a circuit with one another to generate the waveform. Structure including e.g. electrodes is operatively coupled with the capacitors and the control apparatus to apply the waveform to the chest of the patient. The waveform preferably includes an emulated first-phase substantially sinusoidally shaped pulse component having a first polarity. According to biphasic embodiments, the waveform also includes an emulated second-phase substantially sinusoidally shaped pulse component having a second polarity. The control apparatus preferably is constructed to truncate the emulated first-phase pulse component at a predetermined time, preferably based on a design rule used to calculate pulse duration. The design rule calculates the pulse duration to correspond to substantially the peak response of the patient's heart-cell membrane to the first-phase pulse component. Corresponding method embodiments provide additional advantages.

公开(公告)号：US07463923B2

公开(公告)日：2008-12-09

申请号：US10760040

申请日：2004-01-16

申请人： James E. Brewer ,  Gary B. Stendahl ,  Kenneth F. Olson

发明人： James E. Brewer ,  Gary B. Stendahl ,  Kenneth F. Olson

IPC分类号： A61N1/39

CPC分类号： A61N1/3937 ,  A61N1/39 ,  A61N1/3906 ,  A61N1/3912

摘要： An apparatus and method for determining an optimal transchest external defibrillation waveform that provides for variable energy in the first or second phase of a biphasic waveform that, when applied through a plurality of electrodes positioned on a patient's torso, will produce a desired response in the patient's cardiac cell membranes. The method includes the steps of providing a quantitative model of a defibrillator circuit for producing external defibrillation waveforms, the quantitative model of a patient includes a chest component, a heart component, a cell membrane component and a quantitative description of the desired cardiac membrane response function. Finally, a quantitative description of a transchest external defibrillation waveform that will produce the desired cardiac membrane response function is computed. The computation is made as a function of the desired cardiac membrane response function, the patient model and the defibrillator circuit model.

摘要翻译： 一种用于确定最佳交错外部除颤波形的装置和方法，该波形在双相波形的第一或第二相中提供可变能量，当通过位于患者躯干上的多个电极施加时，将在患者的身体中产生期望的响应 心脏细胞膜。 该方法包括提供用于产生外部除颤波形的除颤器电路的定量模型的步骤，患者的定量模型包括胸部组分，心脏组分，细胞膜组分和所需心脏膜响应函数的定量描述 。 最后，计算将产生期望的心脏膜响应函数的经外科除颤波形的定量描述。 作为所需心脏膜响应函数，患者模型和除颤器电路模型的函数进行计算。

公开(公告)号：US5968080A

公开(公告)日：1999-10-19

申请号：US886736

申请日：1997-07-01

申请人： James E. Brewer ,  Gary B. Stendahl ,  Kenneth F. Olson

发明人： James E. Brewer ,  Gary B. Stendahl ,  Kenneth F. Olson

IPC分类号： A61N1/39

CPC分类号： A61N1/3937

摘要： A method for determining an optimal transchest external defibrillation waveform which, when applied through a plurality of electrodes positioned on a patient's torso will produce a desired response in the patient's cardiac cell membranes. The method includes the steps of providing a quantitative model of a defibrillator circuit for producing external defibrillation waveforms, the quantitative model of a patient includes a chest component, a heart component, a cell membrane component and a quantitative description of the desired cardiac membrane response function. Finally, a quantitative description of a transchest external defibrillation waveform that will produce the desired cardiac membrane response function is computed. The computation is made as a function of the desired cardiac membrane response function, the patient model and the defibrillator circuit model.

摘要翻译： 一种用于确定最佳交织外部除颤波形的方法，当通过位于患者躯体上的多个电极施加时，其将在患者的心脏细胞膜中产生期望的响应。 该方法包括提供用于产生外部除颤波形的除颤器电路的定量模型的步骤，患者的定量模型包括胸部组分，心脏组分，细胞膜组分和所需心脏膜响应函数的定量描述 。 最后，计算将产生期望的心脏膜响应函数的经外科除颤波形的定量描述。 作为所需心脏膜响应函数，患者模型和除颤器电路模型的函数进行计算。

公开(公告)号：US5899924A

公开(公告)日：1999-05-04

申请号：US833935

申请日：1997-04-10

申请人： James E. Brewer ,  Gary B. Stendahl

发明人： James E. Brewer ,  Gary B. Stendahl

IPC分类号： A61N1/39

CPC分类号： A61N1/39 ,  A61N1/3906 ,  A61N1/3912 ,  A61N1/3925

摘要： A method and apparatus for delivering a truncated damped sinusoidal external defibrillation waveform which, when applied through a plurality of electrodes positioned on a patient's torso will produce a desired response in the patient's cardiac cell membranes is provided. The method includes the steps monitoring a patient-dependent electrical parameter and determining a duration based on the parameter determined. A first set of charge storage capacitors is then charged. A first truncating switch is then closed to discharge the first set of capacitors. Then, after the duration period that was calculated has expired the switch is opened to truncate the waveform. The computation of discharge duration is made as a function of the desired cardiac membrane response function, a patient model and a defibrillator circuit model.

摘要翻译： 提供截断的阻尼正弦外部除颤波形的方法和装置，该波形在通过位于患者躯体上的多个电极施加时将在患者的心脏细胞膜中产生期望的响应。 该方法包括监视与患者相关的电参数并基于确定的参数来确定持续时间的步骤。 然后对第一组电荷存储电容器充电。 然后关闭第一截断开关以对第一组电容器进行放电。 然后，在计算的持续时间段到期后，开关打开以截断波形。 放电持续时间的计算作为所需心脏膜响应函数，患者模型和除颤器电路模型的函数。

公开(公告)号：US5700281A

公开(公告)日：1997-12-23

申请号：US668117

申请日：1996-06-17

申请人： James E. Brewer ,  Kenneth F. Olson ,  John F. Stolte ,  Nora J. Utke ,  Gary B. Stendahl

发明人： James E. Brewer ,  Kenneth F. Olson ,  John F. Stolte ,  Nora J. Utke ,  Gary B. Stendahl

IPC分类号： A61N1/04 ,  A61N1/08 ,  A61N1/39

CPC分类号： A61N1/04 ,  A61N1/3931 ,  A61N2001/083

摘要： A circuit detectable arrangement of a plurality of medical electrodes is provided with each electrode having an electrically nonconductive backing layer, a layer of electrically conductive adhesive disposed on the backing layer and a lead wire extending therefrom and electrically connected with the conductive adhesive. More specifically, a first electrode is disposed on an electrically nonconductive liner, a second electrode is disposed on an electrically nonconductive liner, and an electrical connector is provided between the first and second electrodes for electrically completing a circuit connecting the lead wire of the first electrode to the lead wire of the second electrode. Preferably, the backing layers of the first and second electrodes each include a conductor portion, and the electrical connector is connected between the conductor portion of the backing layer of the first electrode and the conductor portion of the backing layer of the second electrode. The electrical connector preferably comprises a strip of flexible and electrically conductive material and may include a nonconductive tear resistant strip. Utilizing the electrode packaging above, the present invention monitors the state of the AED and the stage of a rescue. In particular, at least five stages of a rescue are monitored. These include: 1) rescue initiated; 2) preparing victim; 3) applying electrodes; 4) AED in use; and 5) rescue completed.

摘要翻译： 提供了多个医疗电极的电路可检测布置，每个电极具有不导电背衬层，设置在背衬层上的导电粘合剂层和从其延伸并与导电粘合剂电连接的引线。 更具体地，第一电极设置在非导电衬垫上，第二电极设置在非导电衬垫上，并且电连接器设置在第一和第二电极之间，用于电完成连接第一电极的引线的电路 到第二电极的引线。 优选地，第一和第二电极的背衬层各自包括导体部分，并且电连接器连接在第一电极的背衬层的导体部分和第二电极的背衬层的导体部分之间。 电连接器优选地包括柔性和导电材料条，并且可以包括不导电的抗撕裂条带。 利用上述电极封装，本发明监视AED的状态和救援的阶段。 特别是对至少五个营救阶段进行监控。 这些包括：1）救援启动; 2）准备受害人; 3）施加电极; 4）使用中的AED 和5）抢救完成。

公开(公告)号：US06411846B1

公开(公告)日：2002-06-25

申请号：US09678820

申请日：2000-10-04

申请人： James E. Brewer ,  Gary B. Stendahl ,  Kenneth F. Olson

发明人： James E. Brewer ,  Gary B. Stendahl ,  Kenneth F. Olson

IPC分类号： A61N139

CPC分类号： A61N1/3937 ,  A61N1/39 ,  A61N1/3906 ,  A61N1/3912

摘要： An apparatus and method for determining an optimal transchest external defibrillation waveform that provides for variable energy in the first or second phase of a biphasic waveform that, when applied through a plurality of electrodes positioned on a patient's torso, will produce a desired response in the patient's cardiac cell membranes. The method includes the steps of providing a quantitative model of a defibrillator circuit for producing external defibrillation waveforms, the quantitative model of a patient includes a chest component, a heart component, a cell membrane component and a quantitative description of the desired cardiac membrane response function. Finally, a quantitative description of a transchest external defibrillation waveform that will produce the desired cardiac membrane response function is computed. The computation is made as a function of the desired cardiac membrane response function, the patient model and the defibrillator circuit model.

公开(公告)号：US06263239B1

公开(公告)日：2001-07-17

申请号：US09383561

申请日：1999-08-26

申请人： James E. Brewer ,  Gary B. Stendahl ,  Kenneth F. Olson

发明人： James E. Brewer ,  Gary B. Stendahl ,  Kenneth F. Olson

IPC分类号： A61N139

CPC分类号： A61N1/3937 ,  A61N1/3906

摘要： A method for determining an optimal transchest external defibrillation waveform which, when applied through a plurality of electrodes positioned on a patient's torso will produce a desired response in the patient's cardiac cell membranes. The method includes the steps of providing a quantitative model of a defibrillator circuit for producing external defibrillation waveforms, the quantitative model of a patient includes a chest component, a heart component, a cell membrane component and a quantitative description of the desired cardiac membrane response function. Finally, a quantitative description of a transchest external defibrillation waveform that will produce the desired cardiac membrane response function is computed. The computation is made as a function of the desired cardiac membrane response function, the patient model and the defibrillator circuit model.

摘要翻译： 一种用于确定最佳交织外部除颤波形的方法，当通过位于患者躯体上的多个电极施加时，其将在患者的心脏细胞膜中产生期望的响应。 该方法包括提供用于产生外部除颤波形的除颤器电路的定量模型的步骤，患者的定量模型包括胸部组分，心脏组分，细胞膜组分和所需心脏膜响应函数的定量描述 。 最后，计算将产生期望的心脏膜响应函数的经外科除颤波形的定量描述。 作为所需心脏膜响应函数，患者模型和除颤器电路模型的函数进行计算。

公开(公告)号：US5908443A

公开(公告)日：1999-06-01

申请号：US827757

申请日：1997-04-11

申请人： James E. Brewer ,  Gary B. Stendahl

发明人： James E. Brewer ,  Gary B. Stendahl

IPC分类号： A61N1/39 ,  A61N1/390

CPC分类号： A61N1/39 ,  A61N1/3906 ,  A61N1/3912 ,  A61N1/3925

摘要： An apparatus for generating a waveform for use in externally defibrillating the heart of a patient includes a plurality of capacitors chargeable to respective charge potentials. A control apparatus is operatively coupled with the capacitors to sequentially interconnect the capacitors in a circuit with one another to generate the waveform. Structure including e.g. electrodes is operatively coupled with the capacitors and the control apparatus to apply the waveform to the chest of the patient. The waveform preferably includes an emulated first-phase substantially sinusoidally shaped pulse component having a first polarity. According to biphasic embodiments, the waveform also includes an emulated second-phase substantially sinusoidally shaped pulse component having a second polarity. The control apparatus preferably is constructed to truncate the emulated first-phase pulse component at a predetermined time, preferably based on a design rule used to calculate pulse duration. The design rule calculates the pulse duration to correspond to substantially the peak response of the patient's heart-cell membrane to the first-phase pulse component. Corresponding method embodiments provide additional advantages.

摘要翻译： 用于产生用于外部去纤颤患者心脏的波形的装置包括可充电到各个电荷电位的多个电容器。 控制装置与电容器可操作地耦合，以将电路中的电容器彼此顺序地互连以产生波形。 结构包括例如 电极与电容器和控制装置可操作地耦合以将波形施加到患者的胸部。 波形优选地包括具有第一极性的仿真的第一相基本正弦形脉冲分量。 根据两相实施例，波形还包括具有第二极性的仿真的第二相基本正弦形脉冲分量。 控制装置优选地被构造成在预定时间，优选地基于用于计算脉冲持续时间的设计规则截断仿真的第一相脉冲分量。 设计规则计算脉搏持续时间，以对应于患者心脏细胞膜基本上与第一相脉冲分量的峰值响应。 相应的方法实施例提供了额外的优点。

公开(公告)号：US5891172A

公开(公告)日：1999-04-06

申请号：US673195

申请日：1996-06-27

申请人： Gary B. Stendahl ,  James E. Brewer

发明人： Gary B. Stendahl ,  James E. Brewer

IPC分类号： A61N1/39

CPC分类号： A61N1/3931 ,  A61N1/3925 ,  A61N1/3912 ,  A61N1/3981

摘要： Apparatus and method for selecting from a pair of capacitor banks for delivery of positive and negative polarity portions of a biphasic defibrillator pulse with a selector switch circuit for each capacitor bank, the circuit including a solid state phase selector switch preferably made up of a series connected plurality of IGBT's and each phase selector switch having a phase selector driver and select phase control for turning the phase selector switch ON and OFF when desired to start and truncate selected portions of the biphasic defibrillation pulse.

摘要翻译： 用于从一对电容器组中选择用于通过用于每个电容器组的选择器开关电路递送双相除颤器脉冲的正极性和负极性部分的装置和方法，该电路包括固态相位选择器开关，其优选地由串联连接 多个IGBT和每个相位选择器开关具有相选择器驱动器，并且当需要启动和截断双相除颤脉冲的选定部分时，选择相位控制用于使相位选择器开关接通和关断。