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    Cancer-associated antigens and methods of their identification and use
    1.
    发明授权
    Cancer-associated antigens and methods of their identification and use 有权
    癌症相关抗原及其鉴定和使用方法

    公开(公告)号：US07226606B2

    公开(公告)日：2007-06-05

    申请号：US11274856

    申请日：2005-11-16

    申请人： James McArthur ,  Ju-Fay Chang ,  Dale Ando ,  Margo Roberts ,  Jonathan Simons ,  William Nelson

    发明人： James McArthur ,  Ju-Fay Chang ,  Dale Ando ,  Margo Roberts ,  Jonathan Simons ,  William Nelson

    IPC分类号： A61K35/12

    CPC分类号： G01N33/57434 ,  G01N33/574 ,  G01N33/6893

    摘要： The present invention provides novel, isolated, tumor-associated antigens, and methods for identifying such antigens in a biological sample, and of screening for the presence of such an antigen in a biological specimen, wherein the tumor antigen identified reacts with serum from a subject treated with a vaccine comprising a cytokine and proliferation-incompetent tumor cells which express the tumor-associated antigen. Also provided are kits for carrying out the methods of the invention.

    摘要翻译： 本发明提供了新的，分离的肿瘤相关抗原，以及用于在生物样品中鉴定此类抗原的方法，以及筛选生物样品中存在这种抗原的方法，其中所鉴定的肿瘤抗原与来自受试者的血清反应 用包含表达肿瘤相关抗原的细胞因子和增殖不足的肿瘤细胞的疫苗进行治疗。 还提供了用于实施本发明的方法的试剂盒。

    Cancer-associated antigens and methods of their identification and use
    4.
    发明授权
    Cancer-associated antigens and methods of their identification and use 有权
    癌症相关抗原及其鉴定和使用方法

    公开(公告)号：US07645587B2

    公开(公告)日：2010-01-12

    申请号：US11799584

    申请日：2007-05-02

    申请人： James McArthur ,  Ju-Fay Chang ,  Dale Ando ,  Margo Roberts ,  Jonathan Simons ,  William Nelson

    发明人： James McArthur ,  Ju-Fay Chang ,  Dale Ando ,  Margo Roberts ,  Jonathan Simons ,  William Nelson

    IPC分类号： G01N33/53

    CPC分类号： G01N33/57434 ,  G01N33/574 ,  G01N33/6893

    摘要： The present invention provides novel, isolated, tumor-associated antigens, and methods for identifying such antigens in a biological sample, and of screening for the presence of such an antigen in a biological specimen, wherein the tumor antigen identified reacts with serum from a subject treated with a vaccine comprising a cytokine and proliferation-incompetent tumor cells which express the tumor-associated antigen. Also provided are kits for carrying out the methods of the invention.

    摘要翻译： 本发明提供了新的，分离的肿瘤相关抗原，以及用于在生物样品中鉴定此类抗原的方法，以及筛选生物样品中存在这种抗原的方法，其中所鉴定的肿瘤抗原与来自受试者的血清反应 用包含表达肿瘤相关抗原的细胞因子和增殖不足的肿瘤细胞的疫苗进行治疗。 还提供了用于实施本发明的方法的试剂盒。

    Laryngoscope with disposable blade cover
    6.
    发明授权
    Laryngoscope with disposable blade cover 失效
    喉镜与一次性刀片盖

    公开(公告)号：US07695433B2

    公开(公告)日：2010-04-13

    申请号：US11657876

    申请日：2007-01-24

    申请人： Jonathan Simons

    发明人： Jonathan Simons

    IPC分类号： A61B1/267 ,  A61B1/32

    CPC分类号： A61B1/267

    摘要： A laryngoscope for use with a disposable blade cover is provided. The laryngoscope comprises a handle and a blade. The laryngoscope further comprises an actuator system for selectively securing the disposable blade cover about at least a portion of the blade.

    摘要翻译： 提供一种用于一次性刀片盖的喉镜。 喉镜包括手柄和刀片。 喉镜还包括用于选择性地将一次性刀片盖围绕刀片的至少一部分固定的致动器系统。

    Folding tongs
    7.
    发明申请
    Folding tongs 有权
    折叠钳

    公开(公告)号：US20070284899A1

    公开(公告)日：2007-12-13

    申请号：US11448987

    申请日：2006-06-08

    申请人： Jonathan Simons

    发明人： Jonathan Simons

    IPC分类号： B25B9/00

    CPC分类号： B25B9/00

    摘要： A foldable tongs unit of the type having two pivotally joined legs has a storage position in which the legs lie in flush abutting relation so that the total thickness of the tongs unit in its storage position is the thickness of the two legs. Three transversely spaced fingers on each leg, when unstressed, reside in the plane of the leg and provide both the pivotal connection and the resilient bias against which the tongs are operated. The thickness of each of the joined non-flexing fingers is increased at the proximal end of the unit (i.e., at the hinge), permitting the pivot axis to be located substantially in the plane of abutment between the two legs in the storage position of the unit. In the actuation position, the ends of the foreshortened flexing fingers abut non-flexing fingers of the opposite leg to provide the desired resilient gripping function.

    摘要翻译： 具有两个枢轴连接的腿的类型的可折叠钳单元具有一个储存位置，在该储存位置，腿部处于平齐的邻接关系，使得夹持单元在其收纳位置的总厚度是两条腿的厚度。 每个腿上的三个横向间隔开的指状物在不受应力时驻留在腿的平面中，并提供枢转连接和钳子操作的弹性偏压。 每个接合的不弯曲指状物的厚度在单元的近端处（即在铰链处）增加，允许枢转轴线基本位于两条腿之间的邻接平面中，处于储存位置 那个单位。 在致动位置，缩短的弯曲指状物的端部邻接相对腿部的不弯曲的指状物以提供期望的弹性抓握功能。

    Method and apparatus for tamping and scraping
    8.
    发明授权
    Method and apparatus for tamping and scraping 有权
    捣固和刮削的方法和装置

    公开(公告)号：US09084513B2

    公开(公告)日：2015-07-21

    申请号：US13836750

    申请日：2013-03-15

    申请人： Jonathan Simons

    发明人： Jonathan Simons

    IPC分类号： A47J43/28

    CPC分类号： A47J43/288

    摘要： A tamping and scraping tool for a food processor includes a flat blade in the form of a segment of a circle and a handle extending perpendicularly therefrom. The blade has an arcuate circumferential scraping edge and a chordal scraping edge interrupted by a central arcuate recess configured as a smaller circle segment. The flat bottom surface serves as a tamping surface; the chordal scraping edge permits scraping material from the bottom wall of the processor; and the outer scraping edge permits scraping of material from the processor sidewall.

    摘要翻译： 用于食品加工机的捣实和刮削工具包括呈圆形段的平面刀片和从其垂直延伸的手柄。 刀片具有弓形圆周刮削边缘，并且由被构造为较小圆形段的中心弓形凹部中断的弦向刮削边缘。 平底面用作夯实表面; 梭舌刮边允许从处理器的底壁刮去材料; 并且外部刮削刃允许从处理器侧壁刮除材料。

    Laryngoscope
    9.
    发明申请
    Laryngoscope 失效
    喉镜

    公开(公告)号：US20080177147A1

    公开(公告)日：2008-07-24

    申请号：US11657876

    申请日：2007-01-24

    申请人： Jonathan Simons

    发明人： Jonathan Simons

    IPC分类号： A61B1/267

    CPC分类号： A61B1/267

    摘要： A laryngoscope for use with a disposable blade cover is provided. The laryngoscope comprises a handle and a blade. The laryngoscope further comprises an actuator system for selectively securing the disposable blade cover about at least a portion of the blade.

    摘要翻译： 提供一种用于一次性刀片盖的喉镜。 喉镜包括手柄和刀片。 喉镜还包括用于选择性地将一次性刀片盖围绕刀片的至少一部分固定的致动器系统。

    Method and Apparatus for Tamping and Scraping
    10.
    发明申请
    Method and Apparatus for Tamping and Scraping 有权
    捣固和刮刮的方法和装置

    公开(公告)号：US20130255001A1

    公开(公告)日：2013-10-03

    申请号：US13836750

    申请日：2013-03-15

    申请人： Jonathan Simons

    发明人： Jonathan Simons

    IPC分类号： A47J43/28

    CPC分类号： A47J43/288

    摘要： A tamping and scraping tool for a food processor includes a flat blade in the form of a segment of a circle and a handle extending perpendicularly therefrom. The blade has an arcuate circumferential scraping edge and a chordal scraping edge interrupted by a central arcuate recess configured as a smaller circle segment. The flat bottom surface serves as a tamping surface; the chordal scraping edge permits scraping material from the bottom wall of the processor; and the outer scraping edge permits scraping of material from the processor sidewall.

    摘要翻译： 用于食品加工机的捣实和刮削工具包括呈圆形段的平面刀片和从其垂直延伸的手柄。 刀片具有弓形圆周刮削边缘，并且由被构造为较小圆形段的中心弓形凹部中断的弦向刮削边缘。 平底面用作夯实表面; 梭舌刮边允许从处理器的底壁刮去材料; 并且外部刮削刃允许从处理器侧壁刮除材料。