利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

20 条记录 (耗时 0.037 秒)

    Cancer-associated antigens and methods of their identification and use
    2.
    发明授权
    Cancer-associated antigens and methods of their identification and use 有权
    癌症相关抗原及其鉴定和使用方法

    公开(公告)号：US07226606B2

    公开(公告)日：2007-06-05

    申请号：US11274856

    申请日：2005-11-16

    申请人： James McArthur ,  Ju-Fay Chang ,  Dale Ando ,  Margo Roberts ,  Jonathan Simons ,  William Nelson

    发明人： James McArthur ,  Ju-Fay Chang ,  Dale Ando ,  Margo Roberts ,  Jonathan Simons ,  William Nelson

    IPC分类号： A61K35/12

    CPC分类号： G01N33/57434 ,  G01N33/574 ,  G01N33/6893

    摘要： The present invention provides novel, isolated, tumor-associated antigens, and methods for identifying such antigens in a biological sample, and of screening for the presence of such an antigen in a biological specimen, wherein the tumor antigen identified reacts with serum from a subject treated with a vaccine comprising a cytokine and proliferation-incompetent tumor cells which express the tumor-associated antigen. Also provided are kits for carrying out the methods of the invention.

    摘要翻译： 本发明提供了新的，分离的肿瘤相关抗原，以及用于在生物样品中鉴定此类抗原的方法，以及筛选生物样品中存在这种抗原的方法，其中所鉴定的肿瘤抗原与来自受试者的血清反应 用包含表达肿瘤相关抗原的细胞因子和增殖不足的肿瘤细胞的疫苗进行治疗。 还提供了用于实施本发明的方法的试剂盒。

    Cancer-associated antigens and methods of their identification and use
    5.
    发明授权
    Cancer-associated antigens and methods of their identification and use 有权
    癌症相关抗原及其鉴定和使用方法

    公开(公告)号：US07645587B2

    公开(公告)日：2010-01-12

    申请号：US11799584

    申请日：2007-05-02

    申请人： James McArthur ,  Ju-Fay Chang ,  Dale Ando ,  Margo Roberts ,  Jonathan Simons ,  William Nelson

    发明人： James McArthur ,  Ju-Fay Chang ,  Dale Ando ,  Margo Roberts ,  Jonathan Simons ,  William Nelson

    IPC分类号： G01N33/53

    CPC分类号： G01N33/57434 ,  G01N33/574 ,  G01N33/6893

    摘要： The present invention provides novel, isolated, tumor-associated antigens, and methods for identifying such antigens in a biological sample, and of screening for the presence of such an antigen in a biological specimen, wherein the tumor antigen identified reacts with serum from a subject treated with a vaccine comprising a cytokine and proliferation-incompetent tumor cells which express the tumor-associated antigen. Also provided are kits for carrying out the methods of the invention.

    摘要翻译： 本发明提供了新的，分离的肿瘤相关抗原，以及用于在生物样品中鉴定此类抗原的方法，以及筛选生物样品中存在这种抗原的方法，其中所鉴定的肿瘤抗原与来自受试者的血清反应 用包含表达肿瘤相关抗原的细胞因子和增殖不足的肿瘤细胞的疫苗进行治疗。 还提供了用于实施本发明的方法的试剂盒。

    Methods and apparatus for regular expression matching
    9.
    发明授权
    Methods and apparatus for regular expression matching 有权
    正则表达式匹配的方法和装置

    公开(公告)号：US07308446B1

    公开(公告)日：2007-12-11

    申请号：US10340392

    申请日：2003-01-10

    申请人： Rina Panigrahy ,  William Nelson ,  Anh Tien Nguyen

    发明人： Rina Panigrahy ,  William Nelson ,  Anh Tien Nguyen

    IPC分类号： G06F7/26

    CPC分类号： G06F17/30985 ,  Y10S707/99936 ,  Y10S707/99942

    摘要： Methods and apparatus are disclosed for regular expression matching, especially for, but not limited to high-speed applications such as in a packet switching system (e.g., a router). One implementation includes a matching mechanism for processing each character of a plurality of input characters to progressively generate keyword indications of matched keywords as matched keywords are identified, and for generating one or more matching indications of matched base expressions and non-keyword expressions. These indications are received by a matched regular expression detection mechanism which generates one or more matched regular expression indications based on said one or more keyword indications and said one or more matching indications. In one implementation, the matched regular expression detection mechanism maintains a keyword data structure, which is updated as matched keyword indications are received to ensure they are matched in a proper order. One implementation uses a bitmap to track the matched keywords and AND-SHIFT-OR operations to efficiently update the bitmap.

    摘要翻译： 公开了用于正则表达式匹配的方法和装置，特别是对于但不限于诸如在分组交换系统（例如，路由器）中的高速应用。 一个实现包括用于处理多个输入字符的每个字符的匹配机制，以逐渐生成匹配的关键字的关键字指示，因为匹配的关键字被识别，并且用于生成匹配的基本表达和非关键字表达的一个或多个匹配指示。 这些指示由匹配的正则表达式检测机制接收，该机制基于所述一个或多个关键字指示和所述一个或多个匹配指示产生一个或多个匹配的正则表达式指示。 在一个实现中，匹配的正则表达式检测机制保持关键字数据结构，其被接收到匹配的关键字指示而被更新，以确保它们以适当的顺序匹配。 一个实现使用位图来跟踪匹配的关键字和AND-SHIFT-OR操作，以有效地更新位图。

    Spore specific antigen
    10.
    发明申请
    Spore specific antigen 失效
    孢子特异性抗原

    公开(公告)号：US20070231840A1

    公开(公告)日：2007-10-04

    申请号：US11234752

    申请日：2005-09-23

    申请人： Beverly Mangold ,  Jennifer Aldrich ,  William Nelson

    发明人： Beverly Mangold ,  Jennifer Aldrich ,  William Nelson

    IPC分类号： G01N33/569 ,  C07K16/12

    CPC分类号： C07K16/1278 ,  G01N33/56911

    摘要： The invention relates to a Bacillus spore specific antigen. Compositions and methods relating to the antigen are provided along with antibodies against the antigen. The antigen is specific for Bacillus spores relative to the vegetative form of the cells. The antigen is detectable on ungerminated spores. The antibodies may be used to detect the presence of Bacillus spores by use of methods provided herein. The invention also relates to articles of manufacture as well as kits comprising the antibodies which may be used in the detection methods of the invention.

    摘要翻译： 本发明涉及芽孢杆菌特异性抗原。 提供与抗原相关的组合物和方法以及针对抗原的抗体。 相对于细胞的营养形式，抗原对芽孢杆菌是特异性的。 抗原在未发芽的孢子上可检测。 抗体可用于通过使用本文提供的方法检测芽孢杆菌的存在。 本发明还涉及制品以及包含可用于本发明检测方法的抗体的试剂盒。