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公开(公告)号:US09011498B2
公开(公告)日:2015-04-21
申请号:US13018482
申请日:2011-02-01
申请人: James W. Ogilvie , Fred J. Molz, IV
发明人: James W. Ogilvie , Fred J. Molz, IV
CPC分类号: A61B17/7005 , A61B17/7007 , A61B17/701 , A61B17/7011 , A61B17/7032 , A61B17/7035 , A61B17/7037 , A61B2017/564
摘要: The present application discloses methods for treating a spinal deformity. In one embodiment, an elongated member is attached to vertebral members with fasteners. A separate fastener may attach the elongated member to each of the vertebral members. The elongated member may apply a force to limit growth on one side of the vertebral members, such as a convex side of a scoliotic spine. Each fastener may be constructed to limit a direction of growth of the vertebral member thereby applying a specific, corrective force to the vertebral member. The fasteners may allow relative motion between adjacent vertebral members without losing the attachment between the vertebral members and the fasteners. The net result may be controlled modulation of growth to reduce and/or eliminate the spinal deformity through redirection of growth potential.
摘要翻译: 本申请公开了治疗脊柱畸形的方法。 在一个实施例中,细长构件用紧固件附接到椎骨构件。 单独的紧固件可以将细长构件附接到每个椎骨构件。 细长构件可以施加力以限制椎骨构件的一侧上的生长,例如脊柱侧凸的凸侧。 每个紧固件可被构造成限制椎骨构件的生长方向,从而对椎体构件施加特定的矫正力。 紧固件可以允许相邻椎骨构件之间的相对运动,而不会损失脊椎构件和紧固件之间的附接。 最终结果可以是控制生长调节,以通过重新生长潜力来减少和/或消除脊柱畸形。
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公开(公告)号:US20110190826A1
公开(公告)日:2011-08-04
申请号:US13018482
申请日:2011-02-01
申请人: James W. Ogilvie , Fred J. Molz, IV
发明人: James W. Ogilvie , Fred J. Molz, IV
IPC分类号: A61B17/88
CPC分类号: A61B17/7005 , A61B17/7007 , A61B17/701 , A61B17/7011 , A61B17/7032 , A61B17/7035 , A61B17/7037 , A61B2017/564
摘要: The present application discloses methods for treating a spinal deformity. In one embodiment, an elongated member is attached to vertebral members with fasteners. A separate fastener may attach the elongated member to each of the vertebral members. The elongated member may apply a force to limit growth on one side of the vertebral members, such as a convex side of a scoliotic spine. Each fastener may be constructed to limit a direction of growth of the vertebral member thereby applying a specific, corrective force to the vertebral member. The fasteners may allow relative motion between adjacent vertebral members without losing the attachment between the vertebral members and the fasteners. The net result may be controlled modulation of growth to reduce and/or eliminate the spinal deformity through redirection of growth potential.
摘要翻译: 本申请公开了治疗脊柱畸形的方法。 在一个实施例中,细长构件用紧固件附接到椎骨构件。 单独的紧固件可以将细长构件附接到每个椎骨构件。 细长构件可以施加力以限制椎骨构件的一侧上的生长,例如脊柱侧凸的凸侧。 每个紧固件可被构造成限制椎骨构件的生长方向,从而对椎体构件施加特定的矫正力。 紧固件可以允许相邻椎骨构件之间的相对运动,而不会损失脊椎构件和紧固件之间的附接。 最终结果可以是控制生长调节,以通过重新生长潜力来减少和/或消除脊柱畸形。
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公开(公告)号:US07909857B2
公开(公告)日:2011-03-22
申请号:US12055624
申请日:2008-03-26
申请人: James W. Ogilvie , Fred J. Molz, IV
发明人: James W. Ogilvie , Fred J. Molz, IV
IPC分类号: A61B17/88
CPC分类号: A61B17/7005 , A61B17/7007 , A61B17/701 , A61B17/7011 , A61B17/7032 , A61B17/7035 , A61B17/7037 , A61B2017/564
摘要: The present application discloses methods for treating a spinal deformity. In one embodiment, an elongated member is attached to vertebral members with fasteners. A separate fastener may attach the elongated member to each of the vertebral members. The elongated member may apply a force to limit growth on one side of the vertebral members, such as a convex side of a scoliotic spine. Each fastener may be constructed to limit a direction of growth of the vertebral member thereby applying a specific, corrective force to the vertebral member. The fasteners may allow relative motion between adjacent vertebral members without losing the attachment between the vertebral members and the fasteners. The net result may be controlled modulation of growth to reduce and/or eliminate the spinal deformity through redirection of growth potential.
摘要翻译: 本申请公开了治疗脊柱畸形的方法。 在一个实施例中,细长构件用紧固件附接到椎骨构件。 单独的紧固件可以将细长构件附接到每个椎骨构件。 细长构件可以施加力以限制椎骨构件的一侧上的生长,例如脊柱侧凸的凸侧。 每个紧固件可被构造成限制椎骨构件的生长方向,从而对脊椎构件施加特定的矫正力。 紧固件可以允许相邻椎骨构件之间的相对运动,而不会损失脊椎构件和紧固件之间的附接。 最终结果可以是控制生长调节,以通过重新生长潜力来减少和/或消除脊柱畸形。
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公开(公告)号:USD501555S1
公开(公告)日:2005-02-01
申请号:US29185020
申请日:2003-06-19
申请人: Peter Pal Varga , James W. Ogilvie
设计人: Peter Pal Varga , James W. Ogilvie
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公开(公告)号:USD494274S1
公开(公告)日:2004-08-10
申请号:US29185047
申请日:2003-06-19
申请人: Peter Pal Varga , James W. Ogilvie
设计人: Peter Pal Varga , James W. Ogilvie
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公开(公告)号:US20130310261A1
公开(公告)日:2013-11-21
申请号:US13848772
申请日:2013-03-22
CPC分类号: C12Q1/6883 , C12Q2600/118 , C12Q2600/156 , C12Q2600/172 , G16H50/30
摘要: The present invention relates to novel genetic markers associated with scoliosis, risk of developing scoliosis and risk of scoliosis curve progression, and simplified methods and materials for determining whether a human subject has scoliosis, is at risk of developing scoliosis or is at risk of scoliosis curve progression.
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公开(公告)号:US20130288913A1
公开(公告)日:2013-10-31
申请号:US13852932
申请日:2013-03-28
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6876 , C12Q1/68 , C12Q1/6883 , C12Q2600/156 , C40B30/04 , G16Z99/00
摘要: The present invention relates to novel genetic markers associated with scoliosis, risk of developing scoliosis and risk of scoliosis curve progression, and simplified methods and materials for determining whether a human subject has scoliosis, is at risk of developing scoliosis or is at risk of scoliosis curve progression.
摘要翻译: 本发明涉及与脊柱侧凸相关的新型遗传标记,发生脊柱侧弯的风险和脊柱侧弯曲线进展的风险,以及用于确定人类受试者是否患有脊柱侧弯的简化方法和材料是否处于发生脊柱侧凸的风险或处于脊柱侧凸的风险中 进步。
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公开(公告)号:US20120258884A1
公开(公告)日:2012-10-11
申请号:US13526876
申请日:2012-06-19
CPC分类号: C12Q1/6876 , C12Q1/68 , C12Q1/6883 , C12Q2600/156 , C40B30/04 , G16Z99/00
摘要: The present invention relates to novel genetic markers associated with scoliosis, risk of developing scoliosis and risk of scoliosis curve progression, and simplified methods and materials for determining whether a human subject has scoliosis, is at risk of developing scoliosis or is at risk of scoliosis curve progression.
摘要翻译: 本发明涉及与脊柱侧凸相关的新型遗传标记,发生脊柱侧弯的风险和脊柱侧弯曲线进展的风险,以及用于确定人类受试者是否患有脊柱侧弯的简化方法和材料是否处于发生脊柱侧凸的风险或处于脊柱侧凸的风险中 进步。
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公开(公告)号:US20110295369A9
公开(公告)日:2011-12-01
申请号:US12341289
申请日:2008-12-22
申请人: James W. Ogilvie
发明人: James W. Ogilvie
CPC分类号: A61B17/56 , A61B17/70 , A61B2017/00004 , A61B2017/00893 , A61B2017/564 , A61L27/54 , A61L27/58 , A61L2300/414 , A61L2300/416 , A61L2300/43 , A61L2300/45 , A61L2300/604 , A61L2430/38
摘要: The present invention is a bone growth stimulating and promoting cytokine type biological implant preferably comprising PTH coated with a controlled release biodegradable coating that is implanted preferably in the concave side of a scoliotically curved spine in combination with a bone growth inhibiting type biological implant preferably comprising methotrexate or like anti-metabolite coated with a controlled release biodegradable coating that is implanted preferably in the convex side of a scoliotically curved spine. The insertion of the biological implant is highly non-invasion, especially as compared to more conventional spine surgical methods, and the biological implant does not decrease spinal mobility or spinal range of motion.
摘要翻译: 本发明是骨生长刺激和促进细胞因子型生物植入物,优选包含涂覆有控制释放的生物可降解涂层的PTH,其优选地植入在焦虑性弯曲的脊柱的凹侧中,与骨生长抑制型生物植入物组合优选包含甲氨蝶呤 或类似于用可控制的可生物降解的涂层涂覆的抗代谢物,该涂层优选地植入在焦虑弯曲的脊柱的凸面中。 生物植入物的插入是非常非侵入的,特别是与更常规的脊柱手术方法相比,生物植入物不降低脊柱移动性或脊柱运动范围。
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公开(公告)号:US08641738B1
公开(公告)日:2014-02-04
申请号:US13357800
申请日:2012-01-25
申请人: James W. Ogilvie , Kenneth Ward , Lesa M. Nelson
发明人: James W. Ogilvie , Kenneth Ward , Lesa M. Nelson
IPC分类号: A61B17/88
CPC分类号: A61B17/56 , A61B17/70 , A61B2017/00004 , A61B2017/00893 , A61B2017/564 , A61B2017/681 , A61F2/44 , A61F5/024 , A61F2002/448 , A61F2210/0004 , A61F2250/0067 , A61L27/54 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/416 , A61L2300/43 , A61L2300/45 , A61L2300/604 , A61L2430/38
摘要: The present invention is a bone growth stimulating and promoting cytokine type biological implant preferably comprising PTH coated with a controlled release biodegradable coating that is implanted preferably in the concave side of a scoliotically curved spine in combination with a bone growth inhibiting type biological implant preferably comprising methotrexate or like anti-metabolite coated with a controlled release biodegradable coating that is implanted preferably in the convex side of a scoliotically curved spine. The insertion of the biological implant is highly non-invasion, especially as compared to more conventional spine surgical methods, and the biological implant does not decrease spinal mobility or spinal range of motion.
摘要翻译: 本发明是骨生长刺激和促进细胞因子型生物植入物,优选包含涂覆有控制释放的生物可降解涂层的PTH,其优选地植入在焦虑性弯曲的脊柱的凹侧中,与骨生长抑制型生物植入物组合优选包含甲氨蝶呤 或类似于用可控制的可生物降解的涂层涂覆的抗代谢物,该涂层优选地植入在焦虑弯曲的脊柱的凸面中。 生物植入物的插入是非常非侵入的,特别是与更常规的脊柱手术方法相比,生物植入物不降低脊柱移动性或脊柱运动范围。
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