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公开(公告)号：US07960612B2
公开(公告)日：2011-06-14
申请号：US12169527
申请日：2008-07-08
申请人： James Z. Zhang , Frederick D. Hempel , Luc J. Adam , Joseph M. Palys , T. Lynne Reuber , Oliver J. Ratcliffe , Robert A. Creelman , Raymond R. Samaha , Pierre E. Broun
发明人： James Z. Zhang , Frederick D. Hempel , Luc J. Adam , Joseph M. Palys , T. Lynne Reuber , Oliver J. Ratcliffe , Robert A. Creelman , Raymond R. Samaha , Pierre E. Broun
CPC分类号： C07K14/415 , C12N15/8261 , Y02A40/146
摘要： The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties, including increased soluble solids, lycopene, and improved plant volume or yield, as compared to wild-type or control plants. The invention also pertains to expression systems that may be used to regulate these transcription factor polynucleotides, providing constitutive, transient, inducible and tissue-specific regulation.
摘要翻译： 本发明涉及植物转录因子多肽，编码它们的多核苷酸，来自各种植物物种的同系物，以及使用多核苷酸和多肽产生具有有利性质的转基因植物的方法，包括增加的可溶性固体，番茄红素和改良的植物体积， 产量，与野生型或对照植物相比。 本发明还涉及可用于调节这些转录因子多核苷酸的表达系统，提供组成型，瞬时，诱导型和组织特异性调节。
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公开(公告)号：US09676831B2
公开(公告)日：2017-06-13
申请号：US13582046
申请日：2011-03-03
申请人： T. Lynne Reuber , Oliver J. Ratcliffe , Frederick D. Hempel , Luc J. Adam , Cai-Zhong Jiang , Robert A. Creelman , Jose Luis Riechmann , Jacqueline E. Heard , Raymond R. Samaha , Pierre E. Broun , Magnus Hertzberg , Torgny Näsholm
发明人： T. Lynne Reuber , Oliver J. Ratcliffe , Frederick D. Hempel , Luc J. Adam , Cai-Zhong Jiang , Robert A. Creelman , Jose Luis Riechmann , Jacqueline E. Heard , Raymond R. Samaha , Pierre E. Broun , Magnus Hertzberg , Torgny Näsholm
IPC分类号： C12N15/82 , A01H5/00 , C07K14/415
CPC分类号： C07K14/415 , C12N15/8261 , Y02A40/146
摘要： Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to have increased tolerance to an abiotic stress (in some cases, to more than one abiotic stress), increased growth, and/or increased biomass. The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, and/or low nutrient conditions.
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公开(公告)号：US20130061345A1
公开(公告)日：2013-03-07
申请号：US13582046
申请日：2011-03-03
申请人： T. Lynne Reuber , Oliver J. Ratcliffe , Frederick D. Hempel , Luc J. Adam , James S. Keddie , Cai-Zhong Jiang , Robert A. Creelman , Jose Luis Riechmann , Jacqueline E. Heard , Raymond R. Samaha , Pierre E. Broun , Magnus Hertzberg , Torgny Näsholm
发明人： T. Lynne Reuber , Oliver J. Ratcliffe , Frederick D. Hempel , Luc J. Adam , James S. Keddie , Cai-Zhong Jiang , Robert A. Creelman , Jose Luis Riechmann , Jacqueline E. Heard , Raymond R. Samaha , Pierre E. Broun , Magnus Hertzberg , Torgny Näsholm
CPC分类号： C07K14/415 , C12N15/8261 , Y02A40/146
摘要： Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to have increased tolerance to an abiotic stress (in some cases, to more than one abiotic stress), increased growth, and/or increased biomass. The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, and/or low nutrient conditions.
摘要翻译： 掺入核酸构建体（包括表达载体）的转录因子多核苷酸和多肽已经被引入植物中并被异位表达。 已经显示用许多这些构建体转化的转基因植物对非生物胁迫（在一些情况下，多于一种非生物胁迫），增加的生长和/或增加的生物量具有增加的耐受性。 非生物胁迫可以包括例如盐，高渗胁迫，缺水，热，冷，干旱和/或低营养条件。
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4.发明申请公开(公告)号：US20130006342A1
公开(公告)日：2013-01-03
申请号：US13611240
申请日：2012-09-12
CPC分类号： C12Q1/6883 , C12Q2600/112 , C12Q2600/158 , C12Q2600/16 , G01N2800/329
摘要： We hypothesized that gene expression patterns in peripheral blood cells may correlate with TAA disease status, and carried out a comprehensive gene expression survey on peripheral blood cells obtained from TAA patients and normal individuals. A distinct gene expression profile in peripheral blood cells can classify TAA patients from normal individuals. The genes provided by the present teachings define a set of diagnostic markers, thus providing a blood-based gene expression test to facilitate early detection of TAA disease. Methods of distinguishing ascending from descending TAA are also provided, as are methods of distinguishing familial from sporadic TAA.
摘要翻译： 我们假设外周血细胞中的基因表达模式可能与TAA疾病状态相关，并对从TAA患者和正常个体获得的外周血细胞进行综合基因表达调查。 外周血细胞中不同的基因表达谱可以分类来自正常个体的TAA患者。 本教导提供的基因定义了一组诊断标记，从而提供了一种基于血液的基因表达测试，以促进TAA疾病的早期检测。 还提供了区分上升TAA的方法，以及区分家族与散发性TAA的方法。
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5.发明申请公开(公告)号：US20090029868A1
公开(公告)日：2009-01-29
申请号：US11981143
申请日：2007-10-30
CPC分类号： C12Q1/6883 , C12Q2600/112 , C12Q2600/158 , C12Q2600/16 , G01N2800/329
摘要： We hypothesized that gene expression patterns in peripheral blood cells may correlate with TAA disease status, and carried out a comprehensive gene expression survey on peripheral blood cells obtained from TAA patients and normal individuals. A distinct gene expression profile in peripheral blood cells can classify TAA patients from normal individuals. The genes provided by the present teachings define a set of diagnostic markers, thus providing a blood-based gene expression test to facilitate early detection of TAA disease. Methods of distinguishing ascending from descending TAA are also provided, as are methods of distinguishing familial from sporadic TAA.
摘要翻译： 我们假设外周血细胞中的基因表达模式可能与TAA疾病状态相关，并对从TAA患者和正常个体获得的外周血细胞进行综合基因表达调查。 外周血细胞中不同的基因表达谱可以分类来自正常个体的TAA患者。 本教导提供的基因定义了一组诊断标记，从而提供了一种基于血液的基因表达测试，以促进TAA疾病的早期检测。 还提供了区分上升TAA的方法，以及区分家族与散发性TAA的方法。
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