公开(公告)号：US20230285548A1

公开(公告)日：2023-09-14

申请号：US18080639

申请日：2022-12-13

Applicant: Janssen Biotech, Inc.

Inventor： Patrick WILKINSON ,  Manuel Alejandro Sepulveda ,  Charles George Drake ,  Derick Siegel

IPC: A61K39/235 ,  A61K39/285 ,  A61K39/395 ,  A61K45/06

CPC classification number: A61K39/235 ,  A61K39/285 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505

Abstract: Disclosed herein are methods of treating or preventing a myeloproliferative disease, a cancer, or a cardiovascular disease, and methods of inducing an immune response, in a subject having a JAK2V617F substitution and/or a CALR exon 9 mutation.