公开(公告)号：US20200048349A1

公开(公告)日：2020-02-13

申请号：US16418082

申请日：2019-05-21

Applicant: Janssen Biotech, Inc.

Inventor： Francois GAUDET ,  Jill GILES-KOMAR ,  Bradley HEIDRICH ,  Chichi HUANG ,  Colleen KANE ,  Ronan MCDAID ,  Jennifer NEMETH-SEAY

IPC: C07K16/28 ,  A61K39/395 ,  C07K16/30 ,  A61P35/00

Abstract: The present invention relates to antibodies that specifically bind CD3. The present invention relates to antibodies that specifically bind PSMA. The present invention relates to antibodies that specifically bind CD3 and PSMA. The present invention relates to antibodies that specifically bind IL1RAP. The present invention relates to antibodies that specifically bind CD33. The present invention relates to antibodies that specifically bind CD3 and IL1RAP. The present invention relates to antibodies that specifically bind CD3 and CD33. The present invention relates to antibodies that specifically bind TMEFF2. The present invention relates to antibodies that specifically bind CD3 and TMEFF2. The present invention relates to fragments of the antibodies, polynucleotides encoding the antibodies or fragments thereof, and methods of making and using the same.

公开(公告)号：US20240067754A1

公开(公告)日：2024-02-29

申请号：US18461191

申请日：2023-09-05

Applicant: Janssen Biotech, Inc.

Inventor： Jinquan LUO ,  Lauren BOUCHER ,  Michael FELDKAMP ,  Michael DIEM ,  Anthony A. ARMSTRONG ,  Alexey TEPLYAKOV ,  Chichi HUANG

IPC: C07K16/42 ,  C07K14/705 ,  C07K16/00

CPC classification number: C07K16/4283 ,  C07K14/705 ,  C07K16/00 ,  C07K2317/31 ,  C07K2317/524 ,  C07K2317/526 ,  C07K2317/53 ,  C07K2317/567 ,  C07K2317/622 ,  C07K2317/624 ,  C07K2317/94

Abstract: Disclosed are materials and methods for improved single chain variable fragments.