公开(公告)号：US20240067754A1

公开(公告)日：2024-02-29

申请号：US18461191

申请日：2023-09-05

Applicant: Janssen Biotech, Inc.

Inventor： Jinquan LUO ,  Lauren BOUCHER ,  Michael FELDKAMP ,  Michael DIEM ,  Anthony A. ARMSTRONG ,  Alexey TEPLYAKOV ,  Chichi HUANG

IPC: C07K16/42 ,  C07K14/705 ,  C07K16/00

CPC classification number: C07K16/4283 ,  C07K14/705 ,  C07K16/00 ,  C07K2317/31 ,  C07K2317/524 ,  C07K2317/526 ,  C07K2317/53 ,  C07K2317/567 ,  C07K2317/622 ,  C07K2317/624 ,  C07K2317/94

Abstract: Disclosed are materials and methods for improved single chain variable fragments.

公开(公告)号：US20170210799A1

公开(公告)日：2017-07-27

申请号：US15409630

申请日：2017-01-19

Applicant: JANSSEN BIOTECH, INC.

Inventor： Glenn Mark ANDERSON ,  Eric T. BALDWIN ,  Benjamin HARMAN ,  Rosa M.F. CARDOSO ,  Jennifer F. NEMETH-SEAY ,  Ricardo ATTAR ,  Francois GAUDET ,  Yingzhe LI ,  Jinquan LUO ,  Ronan MCDAID ,  Steven C. POMERANTZ ,  Susan H. TAM ,  Alexey TEPLYAKOV ,  Sheng-Jiun WU

IPC: C07K16/28

CPC classification number: C07K16/28 ,  A61K2039/505 ,  C07K16/2803 ,  C07K16/2809 ,  C07K2317/31 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/92

Abstract: Provided herein are isolated antibodies that immunospecifically bind to ROR1, bispecific antibodies comprising an antigen-binding site that immunospecifically binds to ROR1 and an antigen-binding site that immunospecifically binds to CD3, and methods of using the same.