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公开(公告)号:US20240173309A1
公开(公告)日:2024-05-30
申请号:US18495457
申请日:2023-10-26
发明人: Santhosh NEELAMKAVIL , Chengzao SUN , Sandeep SOMANI , Stephanie A. BARROS , Raymond J. PATCH , Jing ZHANG , Douglas RIEXINGER , Charles HENDRICK , Elisabetta BIANCHI , Roberto COSTANTE , Federica ROSOLIA , Martina LOLLOBRIGIDA , Sonia DEL RIZZO , Danila BRANCA , Ashok BHANDARI , James DANIEL , Tran Trung TRAN , Brian FREDERICK
IPC分类号: A61K31/4439 , A61P37/02
CPC分类号: A61K31/4439 , A61P37/02
摘要: The present invention relates to novel lipidated peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salts, solvates and/or other forms thereof, corresponding pharmaceutical compositions, methods and/or uses of the IL-23R inhibitors for treatment of autoimmune inflammation diseases and/or related disorders.
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2.
公开(公告)号:US20240150405A1
公开(公告)日:2024-05-09
申请号:US18492612
申请日:2023-10-23
发明人: Chengzao SUN , Brian Troy FREDERICK , Sandeep SOMANI , Gregory Thomas BOURNE , Raymond PATCH , Ashok BHANDARI , Raffaele INGENITO , Roberto COSTANTE , Danila BRANCA , Elisabetta BIANCHI
IPC分类号: C07K7/64
摘要: The present invention provides novel peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel diseases.
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