-
公开(公告)号:US20170291891A1
公开(公告)日:2017-10-12
申请号:US15632027
申请日:2017-06-23
发明人: Jerôme Emile Georges GUILLEMONT , David Francis Alain LANÇOIS , Magali Madeleine Simone MOTTE , Delphine Yvonne Raymonde LARDEAU , Xavier Marc BOURDREZ , Wendy Mia Albert BALEMANS , Dirk André Emmy ROYMANS
IPC分类号: C07D409/14 , C07D401/12 , C07D213/74 , C07D405/14 , C07D241/20 , C07D401/14
CPC分类号: C07D409/14 , C07D213/74 , C07D241/20 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D417/14
摘要: The invention concerns novel substituted pyridine-piperazinyl analogues of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.
-
公开(公告)号:US20190047989A1
公开(公告)日:2019-02-14
申请号:US16071649
申请日:2017-01-19
发明人: Tim Hugo Maria JONCKERS , David Craig MC GOWAN , Jérôme Émile Georges GUILLEMONT , Werner Constant J EMBRECHTS , Guillaume Jean Maurice MERCEY , Christophe Francis Robert Nestor BUYCK , Wendy Mia Albert BALEMANS , Pierre Jean-Marie Bernard RABOISSON
IPC分类号: C07D403/14 , A61P31/16 , A61K45/06 , A61K39/145 , A61K31/506 , A61K31/517 , A61K31/519 , C07D513/04 , C07D473/34 , A61K31/52 , C07D487/04
摘要: The invention relates to compounds having the structure of formula (I) which can be used for the treatment of or against influenza infections.
-
公开(公告)号:US20180258074A1
公开(公告)日:2018-09-13
申请号:US15779468
申请日:2016-11-25
发明人: Tim Hugo Maria JONCKERS , David Craig MCGOWAN , Jérôme Émile George GUILLLEMONT , Ludwig Paul COOYMANS , Werner Constant Johan EMBRECHTS , Christophe Francis Robert Nest BUYCK , Wendy Mia Albert BALEMANS , Pierre Jean-Marie Bernard RABOISSON
IPC分类号: C07D403/04 , A61K31/53 , A61K45/06 , C07D403/12 , A61K31/506 , C07D487/04 , C07D417/14 , A61P31/16
CPC分类号: C07D403/04 , A61K31/506 , A61K31/53 , A61K45/06 , A61P31/16 , C07D403/12 , C07D417/14 , C07D487/04
摘要: The current invention relates to a compound of formula (I) which can be used for the treatment of, or against viral influenza infections.
-
4.SUBSTITUTED PYRIDINE-PIPERAZINYL ANALOGUES AS RSV ANTIVIRAL COMPOUNDS 审中-公开
标题翻译: 作为RSV抗病毒化合物的取代的吡啶 - 哌嗪类似物公开(公告)号:US20160168124A1
公开(公告)日:2016-06-16
申请号:US14908866
申请日:2014-07-29
发明人: Jerôme Emile Georges GUILLEMONT , David Francis Alain LANÇOIS , Magali Madeleine Sirnone MOTTE , Delohine Yvonne Raymonde LARDEAU , Xavier MARC BOURDREZ , Wendy Mia Albert BALEMANS , Dirk André Emmy ROYMANS
IPC分类号: C07D401/14 , C07D417/14 , C07D405/14 , C07D241/20 , C07D401/12
摘要: The invention concerns novel substituted pyridine-piperazinyl analogues of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.
摘要翻译: 本发明涉及具有抗病毒活性的式(I)的新型取代的吡啶 - 哌嗪基类似物,特别是对呼吸道合胞病毒(RSV)的复制具有抑制活性。 本发明还涉及这种新型化合物的制备,包含这些化合物的组合物和用于治疗呼吸道合胞病毒感染的化合物。
-
公开(公告)号:US20190023713A1
公开(公告)日:2019-01-24
申请号:US16068315
申请日:2017-01-05
发明人: Jérôme Émile Georges GUILLEMONT , Wendy Mia Albert BALEMANS , David Craig MC GOWAN , Magali Madeleine Simone MOTTE , David Francis Alain LANÇOIS , Emilie Marie LAMBERT
IPC分类号: C07D487/04 , A61K31/519 , C07D471/04 , A61K31/506 , A61K31/444 , A61K45/06 , A61P31/12
CPC分类号: C07D487/04 , A61K31/444 , A61K31/506 , A61K31/519 , A61K45/06 , A61P31/12 , C07D471/04
摘要: The invention relates to compounds having the structure of formula (I) which can be used for the treatment of or against influenza infections.
-
-
-
-