公开(公告)号：US20080109088A1

公开(公告)日：2008-05-08

申请号：US11865891

申请日：2007-10-02

申请人： Jason Galdonik ,  Matthew Ogle ,  Jim Pokorney ,  Thomas Hinnenkamp

发明人： Jason Galdonik ,  Matthew Ogle ,  Jim Pokorney ,  Thomas Hinnenkamp

IPC分类号： A61F2/02

CPC分类号： A61F2/01 ,  A61F2/013 ,  A61F2230/0006 ,  A61F2230/005 ,  A61M25/09 ,  A61M2025/09175 ,  B33Y80/00

摘要： Improved embolism protection devices comprises fibers that can have one configuration for delivery of the device and a second configuration in which the device is deployed for filtering of flow within a vessel. In some embodiments, the fibers can be connected to a fiber support, which is connected to an actuating element. The actuating element controls the transition from the delivery configuration to the deployed configuration. The embolism protection device can comprise a guidewire. The fibers can be attached at one end to a fiber support structure and at another end to the guidewire. A hypotube can be attached to the proximal end of the fibers while the guidewire is attached at the distal end of the fibers with the guidewire extending within a central channel of the hypotube. The hypotube can be used to guide the delivery of treatment structures, such as a balloon and/or a stent.

摘要翻译： 改进的栓塞保护装置包括可以具有用于装置的输送的一种配置的纤维和其中部署用于过滤容器内的流动的装置的第二配置。 在一些实施例中，纤维可以连接到连接到致动元件的纤维支撑件。 致动元件控制从传送配置到部署配置的过渡。 栓塞保护装置可以包括导丝。 纤维的一端可以连接到纤维支撑结构，另一端可以连接到导丝。 海波管可以附着在纤维的近端，而导丝被连接在纤维的远端，导丝延伸在海波管的中心通道内。 海波管可用于引导治疗结构的传送，例如气囊和/或支架。

公开(公告)号：US20050085847A1

公开(公告)日：2005-04-21

申请号：US10795131

申请日：2004-03-06

申请人： Jason Galdonik ,  Matthew Ogle ,  Jim Pokorney ,  Thomas Hinnenkamp

发明人： Jason Galdonik ,  Matthew Ogle ,  Jim Pokorney ,  Thomas Hinnenkamp

IPC分类号： A61B20060101 ,  A61M25/09 ,  A61M25/12 ,  A61M29/00 ,  G02B6/00

CPC分类号： A61F2/01 ,  A61F2/013 ,  A61F2230/0006 ,  A61F2230/005 ,  A61M25/09 ,  A61M2025/09175 ,  B33Y80/00

摘要： Improved embolism protection devices comprises fibers that can have one configuration for delivery of the device and a second configuration in which the device is deployed for filtering of flow within a vessel. In some embodiments, the fibers can be connected to a fiber support, which is connected to an actuating element. The actuating element controls the transition from the delivery configuration to the deployed configuration. The embolism protection device can comprise a guidewire. The fibers can be attached at one end to a fiber support structure and at another end to the guidewire. A hypotube can be attached to the proximal end of the fibers while the guidewire is attached at the distal end of the fibers with the guidewire extending within a central channel of the hypotube. The hypotube can be used to guide the delivery of treatment structures, such as a balloon and/or a stent.

摘要翻译： 改进的栓塞保护装置包括可以具有用于装置的输送的一种配置的纤维和其中部署用于过滤容器内的流动的装置的第二配置。 在一些实施例中，纤维可以连接到连接到致动元件的纤维支撑件。 致动元件控制从传送配置到部署配置的过渡。 栓塞保护装置可以包括导丝。 纤维的一端可以连接到纤维支撑结构，另一端可以连接到导丝。 海波管可以附着在纤维的近端，而导丝被连接在纤维的远端，导丝延伸在海波管的中心通道内。 海波管可用于引导治疗结构的传送，例如气囊和/或支架。

公开(公告)号：US20080086110A1

公开(公告)日：2008-04-10

申请号：US11791071

申请日：2005-11-21

申请人： Jason Galdonik ,  Peter Dardi ,  Matthew Ogle ,  Gregory Boldenow ,  Edward Anderson

发明人： Jason Galdonik ,  Peter Dardi ,  Matthew Ogle ,  Gregory Boldenow ,  Edward Anderson

IPC分类号： A61M31/00 ,  A61F2/06 ,  A61M25/00

CPC分类号： A61M25/00

摘要： Aspiration catheters generally comprise a tube or shaft with an aspiration opening at or near its distal end and a suction device that is at or near the proximal end of the catheter. An aspiration lumen extends from the suction device to the aspiration opening. The aspiration catheter can be associated with an extendable device such that their functions can be combined advantageously. The extendable device can function as a treatment structure and/or as a flow modifier. A treatment structure can be used to expand a constriction in a vessel or to deliver a treatment element into the vessel. A flow modifier generally controls the flow to decrease flow in the vicinity of the aspiration opening to improve the efficiency of the aspiration. Various relationships between the extendable structure and the aspiration catheter are described. Balloons can be used effectively as treatment structures or flow modifiers, although self-extending stents can be used as treatment structures and flaps or the like can be used as flow modifiers.

摘要翻译： 吸入导管通常包括在其远端处或其近端具有抽吸开口的管或轴，以及位于或接近导管近端的抽吸装置。 抽吸腔从抽吸装置延伸到抽吸开口。 抽吸导管可以与可延伸装置相关联，使得它们的功能可以有利地组合。 可延伸装置可用作处理结构和/或作为流动调节剂。 治疗结构可用于扩张血管中的收缩或将治疗元件输送到血管中。 流动调节器通常控制流动以减少抽吸开口附近的流动，以提高抽吸效率。 描述了可延伸结构和抽吸导管之间的各种关系。 气球可以有效地用作治疗结构或流动改进剂，尽管自扩展支架可以用作治疗结构，并且襟翼等可以用作流动改性剂。

公开(公告)号：US20060189921A1

公开(公告)日：2006-08-24

申请号：US11406853

申请日：2006-04-19

申请人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney

发明人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney

IPC分类号： A61M1/00

CPC分类号： A61B17/22 ,  A61B2017/22034 ,  A61B2017/22035 ,  A61B2017/22079 ,  A61B2217/005 ,  A61F2/01

摘要： Methods for the removal of an embolism protection device use aspiration during the drawing of the embolism protection device into the catheter. Generally, the embolism protection device comprises a three dimensional filtering matrix that provides improved filtering without blocking the flow through the patient's vessel. In some embodiments, the embolism protection device can be actuated between a deployed configuration and a removal configuration with a reduced area across the cross section of the vessel lumen. The embolism protection device in the removal configuration can be drawn within the aspiration catheter. The aspiration catheter can have a distal portion with an expanded compartment with an average diameter at least about 20 percent larger than the average diameter of the shaft of the catheter within about 10 centimeters of the expanded compartment. In a rapid exchange version, the rapid exchange segment can have a length of at least about 10 centimeters.

摘要翻译： 在将栓塞保护装置拉入导管期间，用于去除栓塞保护装置的方法使用抽吸。 通常，栓塞保护装置包括三维过滤矩阵，其提供改进的过滤而不阻塞通过患者血管的流动。 在一些实施例中，栓塞保护装置可以在展开构造和移除构造之间被致动，并且在血管内腔的横截面上具有减小的面积。 拔除结构中的栓塞保护装置可以在抽吸导管内拉出。 抽吸导管可以具有远端部分，其具有扩张隔室，平均直径比扩张隔室的约10厘米内的导管轴的平均直径至少大约20％。 在快速交换版本中，快速交换段可以具有至少约10厘米的长度。

公开(公告)号：US20080172066A9

公开(公告)日：2008-07-17

申请号：US11494783

申请日：2006-07-27

申请人： Jason Galdonik ,  Matthew Ogle

发明人： Jason Galdonik ,  Matthew Ogle

IPC分类号： A61B17/26

CPC分类号： A61B17/22 ,  A61B17/221 ,  A61B17/320725 ,  A61B2017/00778 ,  A61B2017/22001 ,  A61B2017/22038 ,  A61B2017/22084 ,  A61B2017/320733 ,  A61B2017/320741 ,  A61B2217/005

摘要： Embolectomy procedures can be performed under conditions to effectively remove thrombus/emboli with little risk of injuring the vessel wall and while effectively capturing and removing emboli. Desired embolectomy devices present a polymer matrix against the vessel wall. Suction can be used to facilitate the embolectomy process and to remove emboli loosened in the procedure. Some devices combine features to present a polymer matrix against the vessel wall while corresponding providing sufficient support to effectively loosen thrombus. Combinations of embolectomy and/or filter elements can be used.

摘要翻译： 可以在有效去除血栓/栓塞的条件下进行结肠切除术程序，几乎没有损伤血管壁的危险，同时有效地捕获和去除栓塞。 所需的止血器切除装置将聚合物基质存在于血管壁上。 吸引可用于促进膀胱切除术过程，并清除手术中松动的栓塞。 一些装置结合特征以呈现针对血管壁的聚合物基质，同时相应地提供足够的支持以有效地松开血栓。 可以使用结肠切除术和/或过滤元件的组合。

公开(公告)号：US20070172526A1

公开(公告)日：2007-07-26

申请号：US11603315

申请日：2006-11-21

申请人： Jason Galdonik ,  Matthew Ogle ,  Bruce Ebner

发明人： Jason Galdonik ,  Matthew Ogle ,  Bruce Ebner

IPC分类号： A61K9/14

CPC分类号： A61K49/0409

摘要： Medical devices with radiopaque three dimensional filtration matrices provide for improved visualization of the device within a vessel. In some embodiments, the three dimensional filtration matrix comprises fibers, such as surface capillary fibers. Visualization of the three dimensional filtration matrix provides for an evaluation of the proper deployment of the three dimensional filtration matrix. Radiopaque surface capillary fibers can be advantageously incorporated into other medical devices. Radiopaque surface capillary fibers can be formed by extrusion of a radiopaque polymer or polymer composite.

摘要翻译： 具有不透射线的三维过滤基质的医疗装置提供容器内装置的改进的可视化。 在一些实施例中，三维过滤基质包括纤维，例如表面毛细纤维。 三维过滤矩阵的可视化提供了三维过滤矩阵的适当部署的评估。 不透射线的表面毛细纤维可以有利地结合到其他医疗装置中。 不透射线的表面毛细纤维可以通过挤出不透射线的聚合物或聚合物复合材料形成。

公开(公告)号：US20070060911A1

公开(公告)日：2007-03-15

申请号：US11409147

申请日：2006-04-21

申请人： Mark Webster ,  Jason Galdonik ,  Matthew Ogle

发明人： Mark Webster ,  Jason Galdonik ,  Matthew Ogle

IPC分类号： A61M25/00

CPC分类号： A61M25/0041 ,  A61B17/22 ,  A61B2017/22039 ,  A61B2217/005 ,  A61M25/005 ,  A61M25/0052 ,  A61M25/0054 ,  A61M25/0068 ,  A61M25/007 ,  A61M25/0074 ,  A61M25/008 ,  A61M25/10 ,  A61M2025/0063 ,  A61M2025/0183 ,  A61M2025/1052

摘要： Thrombectomy catheters are presented that have curved tip portions. A suction lumen extends from at or near the proximal end of the catheter to a suction port at or near the tip portion of the catheter. The curves of the thrombectomy catheter can be selected to place a suction port at or near a vessel wall for the more effective removal of thrombus resulting from directing the suction in the direction of the thrombus. In some embodiments, the tip portion of the catheter can be transitioned from a first configuration for delivery of the catheter into the vessel to a second more curved configuration with a desired design for application of suction. The catheter can be moved in a circumferential and/or lateral direction to cover selected portions of the inner vessel wall. In some embodiments, a partially occlusive structure can be used to reduce and/or redirect flow within the vessel to improve performance of the thrombectomy.

摘要翻译： 呈现出具有弯曲尖端部分的血栓切除导管。 吸入腔从导管的近端处或附近延伸到导管尖端部分处或附近的吸入口。 可以选择血栓切除术导管的曲线以将血管口置于血管壁或血管壁附近，以便更有效地从血栓方向引导吸引血栓。 在一些实施例中，导管的尖端部分可以从用于将导管输送到容器中的第一构型转变成具有用于施加抽吸的期望设计的第二更弯曲构造。 导管可以在周向和/或横向移动以覆盖内部血管壁的选定部分。 在一些实施方案中，可以使用部分封闭结构来减少和/或重定向血管内的流动，以改善血栓切除术的性能。

公开(公告)号：US20070038226A1

公开(公告)日：2007-02-15

申请号：US11494783

申请日：2006-07-27

申请人： Jason Galdonik ,  Matthew Ogle

发明人： Jason Galdonik ,  Matthew Ogle

IPC分类号： A61B17/26

CPC分类号： A61B17/22 ,  A61B17/221 ,  A61B17/320725 ,  A61B2017/00778 ,  A61B2017/22001 ,  A61B2017/22038 ,  A61B2017/22084 ,  A61B2017/320733 ,  A61B2017/320741 ,  A61B2217/005

摘要： Embolectomy procedures can be performed under conditions to effectively remove thrombus/emboli with little risk of injuring the vessel wall and while effectively capturing and removing emboli. Desired embolectomy devices present a polymer matrix against the vessel wall. Suction can be used to facilitate the embolectomy process and to remove emboli loosened in the procedure. Some devices combine features to present a polymer matrix against the vessel wall while corresponding providing sufficient support to effectively loosen thrombus. Combinations of embolectomy and/or filter elements can be used.

摘要翻译： 可以在有效去除血栓/栓塞的条件下进行结肠切除术程序，几乎没有损伤血管壁的危险，同时有效地捕获和去除栓塞。 所需的止血器切除装置将聚合物基质存在于血管壁上。 吸引可用于促进膀胱切除术过程，并清除手术中松动的栓塞。 一些装置结合特征以呈现针对血管壁的聚合物基质，同时相应地提供足够的支持以有效地松开血栓。 可以使用结肠切除术和/或过滤元件的组合。

公开(公告)号：US20060200047A1

公开(公告)日：2006-09-07

申请号：US11072001

申请日：2005-03-04

申请人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney ,  Kavitha Ganesan ,  Grace Wlodarski

发明人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney ,  Kavitha Ganesan ,  Grace Wlodarski

IPC分类号： A61M29/00 ,  A61M25/00

CPC分类号： A61M25/0138 ,  A61M25/0054 ,  A61M25/0133

摘要： An integrated guiding device has a tube and a corewire within the tube and a torque coupler. The torque coupler can couple the rotational motion of the tube with the rotational motion of the corewire. The wire can be moved longitudinally at least some amount relative to the tube. The device can further comprise a functional medical structure, such as an embolism protection structure. The device can be used in medical procedures, such as less invasive procedures within the cardiovascular system. Improved fiber based embolism protection devices comprise fiber bundles that are twisted prior to delivery.

摘要翻译： 集成引导装置在管内具有管和芯线，以及扭矩耦合器。 扭矩耦合器可将管的旋转运动与芯线的旋转运动耦合。 电线可以相对于管子至少一定数量的纵向移动。 该装置还可以包括诸如栓塞保护结构的功能医疗结构。 该装置可用于医疗程序，例如心血管系统内的侵入性较小的程序。 改进的基于纤维的栓塞保护装置包括在输送之前被扭曲的纤维束。

公开(公告)号：US20050277976A1

公开(公告)日：2005-12-15

申请号：US10854920

申请日：2004-05-27

申请人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney

发明人： Jason Galdonik ,  Matthew Ogle ,  James Pokorney

IPC分类号： A61B17/22 ,  A61F2/01 ,  A61M1/00 ,  A61M29/00

CPC分类号： A61B17/22 ,  A61B2017/22034 ,  A61B2017/22035 ,  A61B2017/22079 ,  A61B2217/005 ,  A61F2/01

摘要： Methods for the removal of an embolism protection device use aspiration during the drawing of the embolism protection device into the catheter. Generally, the embolism protection device comprises a three dimensional filtering matrix that provides improved filtering without blocking the flow through the patient's vessel. In some embodiments, the embolism protection device can be actuated between a deployed configuration and a removal configuration with a reduced area across the cross section of the vessel lumen. The embolism protection device in the removal configuration can be drawn within the aspiration catheter. The aspiration catheter can have a distal portion with an expanded compartment with an average diameter at least about 20 percent larger than the average diameter of the shaft of the catheter within about 10 centimeters of the expanded compartment. In a rapid exchange version, the rapid exchange segment can have a length of at least about 10 centimeters.

摘要翻译： 在将栓塞保护装置拉入导管期间，用于去除栓塞保护装置的方法使用抽吸。 通常，栓塞保护装置包括三维过滤矩阵，其提供改进的过滤而不阻塞通过患者血管的流动。 在一些实施例中，栓塞保护装置可以在展开构造和移除构造之间被致动，并且在血管内腔的横截面上具有减小的面积。 拔除结构中的栓塞保护装置可以在抽吸导管内拉出。 抽吸导管可以具有远端部分，其具有扩张隔室，平均直径比扩张隔室的约10厘米内的导管轴的平均直径至少大约20％。 在快速交换版本中，快速交换段可以具有至少约10厘米的长度。