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21 条记录 (耗时 0.024 秒)

    Method for compensating for induced artifacts on an image to be printed
    1.
    发明申请
    Method for compensating for induced artifacts on an image to be printed 有权
    用于补偿要印刷的图像上的诱发伪影的方法

    公开(公告)号：US20060132538A1

    公开(公告)日：2006-06-22

    申请号：US11016250

    申请日：2004-12-17

    申请人： Je-Ho Lee ,  Jay Gondek ,  Morgan Schramm

    发明人： Je-Ho Lee ,  Jay Gondek ,  Morgan Schramm

    IPC分类号： B41J2/21

    CPC分类号： B41J2/2132 ,  B41J29/393

    摘要： A method for compensating for induced artifacts on an image to be printed includes processing the image to be printed. An image region of the image susceptible to at least one artifact is identified. An imaging process is modified to reduce an effect of the at least one artifact on the image region. The image is printed.

    摘要翻译： 用于补偿要打印的图像上的诱发伪影的方法包括处理要打印的图像。 识别易受至少一个伪像的图像的图像区域。 修改成像处理以减少图像区域上的至少一个伪像的影响。 打印图像。

    Method to detect previous sharpening of an image to preclude oversharpening
    2.
    发明申请
    Method to detect previous sharpening of an image to preclude oversharpening 审中-公开
    检测图像的先前锐化以防止过度锐化的方法

    公开(公告)号：US20060245665A1

    公开(公告)日：2006-11-02

    申请号：US11118826

    申请日：2005-04-29

    申请人： Je-Ho Lee ,  Jay Gondek

    发明人： Je-Ho Lee ,  Jay Gondek

    IPC分类号： G06K9/40

    CPC分类号： G06T5/004 ,  G06T5/20 ,  G06T7/13 ,  G06T2207/20012 ,  G06T2207/20192

    摘要： Disclosed are methods of processing digital images to detect previous sharpening of the images by sequentially examining characteristics of individual pixels within the image and the neighborhood of pixels immediately surrounding the individual pixels. Detection of previous sharpening allows detrimental oversharpening to be avoided. Also disclosed are methods of determining whether a digital image has been previously sharped and, based upon that determination, selectively sharpening the image.

    摘要翻译： 公开了处理数字图像以通过顺序检查图像内的各个像素的特征和紧邻各个像素的像素的邻域来检测图像的先前锐化的方法。 检测以前的磨削可以避免有害的过敏。 还公开了确定数字图像是否已经被预先锐化的方法，并且基于该确定来选择性地锐化图像。

    Agent that inhibits angiogenesis and metastasis targeting mTOR signaling pathway
    4.
    发明授权
    Agent that inhibits angiogenesis and metastasis targeting mTOR signaling pathway 有权
    抑制血管发生和转移靶向mTOR信号通路的药物

    公开(公告)号：US09439944B2

    公开(公告)日：2016-09-13

    申请号：US12107492

    申请日：2008-04-22

    申请人： Kyoungsook Park ,  Je-Ho Lee ,  Kyusam Choi

    发明人： Kyoungsook Park ,  Je-Ho Lee ,  Kyusam Choi

    IPC分类号： A61K38/17 ,  A61P35/00 ,  A61K38/16

    CPC分类号： A61K38/16

    摘要： The present invention relates to a novel function of Msx1 protein for inhibiting tumor angiogenesis and metastasis by targeting mTOR (mammalian target of rapamycin) signaling pathway, and for treating a cancer in a subject. Particularly, Msx1 suppresses mTOR through a direct interaction with mTOR, resulting in the inhibition of angiogenesis. The Msx1 significantly suppresses tumor angiogenesis that is necessary for the growth, invasion, and metastasis of solid tumors. Ad-Msx1 can be used to effectively inhibit tumor metastasis by suppressing angiogenesis, tumor cell invasion, and migration.

    摘要翻译： 本发明涉及通过靶向mTOR（雷帕霉素的哺乳动物靶标）信号通路和用于治疗受试者的癌症的Msx1蛋白质用于抑制肿瘤血管生成和转移的新功能。 特别地，Msx1通过与mTOR的直接相互作用抑制mTOR，导致血管生成的抑制。 Msx1显着抑制实体瘤生长，侵袭和转移所必需的肿瘤血管生成。 Ad-Msx1可用于通过抑制血管生成，肿瘤细胞侵袭和迁移来有效抑制肿瘤转移。

    Color map selection
    5.
    发明授权
    Color map selection 有权
    彩色地图选择

    公开(公告)号：US07463385B2

    公开(公告)日：2008-12-09

    申请号：US11173010

    申请日：2005-06-30

    申请人： Jay S. Gondak ,  Je-Ho Lee ,  Ranjit Bhaskar

    发明人： Jay S. Gondak ,  Je-Ho Lee ,  Ranjit Bhaskar

    IPC分类号： G06K15/00

    CPC分类号： G06K15/00 ,  H04N1/6022

    摘要： Systems, devices, and methods performed by program instructions, are provided for color map selection. One method includes instructions which execute to generate a first color map from a set of colors. The instructions execute to generate a second color map from the set of colors and an additional color and to select a color value from between the first color map and the second color map dependent on a presence of the additional color.

    摘要翻译： 提供了程序指令执行的系统，设备和方法，用于选择颜色图。 一种方法包括执行从一组颜色生成第一颜色图的指令。 执行指令以从该组颜色和附加颜色生成第二颜色图，并且根据附加颜色的存在从第一颜色图和第二颜色图之间选择颜色值。

    Agent for inducing apoptosis comprising MSX1 or a gene encoding the same as an active ingredient
    6.
    发明授权
    Agent for inducing apoptosis comprising MSX1 or a gene encoding the same as an active ingredient 有权
    用于诱导凋亡的药剂，其包含MSX1或编码其作为活性成分的基因

    公开(公告)号：US08183218B2

    公开(公告)日：2012-05-22

    申请号：US12253418

    申请日：2008-10-17

    申请人： Je-Ho Lee ,  Kyoungsook Park

    发明人： Je-Ho Lee ,  Kyoungsook Park

    IPC分类号： A61K48/00

    CPC分类号： A61K48/005 ,  A61K38/1709

    摘要： The present invention relates to a novel use of Msx1 protein or a nucleotide encoding the same for inducing apoptosis. The Msx1 of the present invention induces apoptosis through direct interaction with p53 via a homeodomain and such interaction leads to increased stability, and/or nuclear localization of p53 in cells. The Msx1 or homeodomain thereof can be effectively used for the treatment of tumors, in which wild-type p53 protein has lost its function by some mechanism that inactivates p53 proteins.

    摘要翻译： 本发明涉及Msx1蛋白的新用途或编码该Msx1蛋白的核苷酸诱导凋亡的新用途。 本发明的Msx1通过与同源结构域的p53直接相互作用诱导细胞凋亡，并且这种相互作用导致p53在细胞中的稳定性增加和/或核定位。 其Msx1或同源结构域可以有效地用于治疗肿瘤，其中野生型p53蛋白通过使p53蛋白失活的一些机制失去其功能。

    Halftoning algorithm adapted to prevent unaesthetic output
    7.
    发明授权
    Halftoning algorithm adapted to prevent unaesthetic output 有权

    公开(公告)号：US06995868B2

    公开(公告)日：2006-02-07

    申请号：US09895967

    申请日：2001-06-29

    申请人： Jason Quintana ,  Morgan T. Schramm ,  Je-Ho Lee

    发明人： Jason Quintana ,  Morgan T. Schramm ,  Je-Ho Lee

    IPC分类号： H04N1/52 ,  H04N1/58

    CPC分类号： H04N1/52

    摘要： A halftoning method and apparatus reduces the occurrence of unaesthetic color print output associated with the different relationships found in the numeric data contained within the color data planes. The calculation, modification and distribution of error values, resulting from the mismatch between color plane values and firing thresholds, are performed in a manner that minimizes unaesthetic conditions. Error values are modified by use of error modification functions, bitmaps and matrixes. Firing decisions are based on a comparison of the modified error.