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    Substituted thieno[3,2-d]pyrimidines as HIV inhibitors
    1.
    发明授权
    Substituted thieno[3,2-d]pyrimidines as HIV inhibitors 失效
    取代噻吩并[3,2-d]嘧啶作为HIV抑制剂

    公开(公告)号：US08211898B2

    公开(公告)日：2012-07-03

    申请号：US12504566

    申请日：2009-07-16

    申请人： Jean-Luc Girardet ,  Zhi Hong ,  Stephanie Shaw ,  Yung-hyo Koh

    发明人： Jean-Luc Girardet ,  Zhi Hong ,  Stephanie Shaw ,  Yung-hyo Koh

    IPC分类号： C07D495/04 ,  C07D403/12 ,  A61K31/502 ,  A61K31/519 ,  A61P31/14

    CPC分类号： C07D495/04

    摘要： This application concerns certain 4-cyanophenylamino-substituted bicyclic heterocycles of formula I where the dashed line represents a double bond that may be located either between A and C(V) or between C(V) and D, where A is S or C(Z); D is S or C(W); provided that one and only one of A and D is S; where T is NH, O, or S; and where other substituents are defined herein. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.

    摘要翻译： 本申请涉及式I的某些4-氰基苯基氨基取代的双环杂环，其中虚线表示可以位于A和C（V）之间或C（V）和D之间的双键，其中A是S或C（ Z）; D为S或C（W）; A和D中只有一个是S; 其中T是NH，O或S; 并且其中其它取代基在本文中定义。 这些化合物是非核苷逆转录酶抑制剂，具有抗HIV治疗的潜力。

    4-CYANOPHENYLAMINO-SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS HIV INHIBITORS
    2.
    发明申请
    4-CYANOPHENYLAMINO-SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS HIV INHIBITORS 失效
    作为艾滋病毒抗体的4-氰基亚氨基取代的双环杂环化合物

    公开(公告)号：US20090281124A1

    公开(公告)日：2009-11-12

    申请号：US12504566

    申请日：2009-07-16

    申请人： Jean-Luc Girardet ,  Zhi Hong ,  Stephanie Shaw ,  Yung-hyo Koh

    发明人： Jean-Luc Girardet ,  Zhi Hong ,  Stephanie Shaw ,  Yung-hyo Koh

    IPC分类号： A61K31/519 ,  A61P31/12

    CPC分类号： C07D495/04

    摘要： This application concerns certain 4-cyanophenylamino-substituted bicyclic heterocycles of formula I where the dashed line represents a double bond that may be located either between A and C(V) or between C(V) and D, where A is S or C(Z); D is S or C(W); provided that one and only one of A and D is S; where T is NH, O, or S; and where other substituents are defined herein. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.

    摘要翻译： 本申请涉及式I的某些4-氰基苯基氨基取代的双环杂环，其中虚线表示可以位于A和C（V）之间或C（V）和D之间的双键，其中A是S或C（ Z）; D为S或C（W）; A和D中只有一个是S; 其中T是NH，O或S; 并且其中其它取代基在本文中定义。 这些化合物是非核苷逆转录酶抑制剂，具有抗HIV治疗的潜力。

    Substituted thieno [2,3-d] pyrimidines as HIV inhibitors
    4.
    发明授权
    Substituted thieno [2,3-d] pyrimidines as HIV inhibitors 失效
    取代噻吩并[2,3-d]嘧啶作为HIV抑制剂

    公开(公告)号：US08324223B2

    公开(公告)日：2012-12-04

    申请号：US13470119

    申请日：2012-05-11

    申请人： Jean-Luc Girardet ,  Zhi Hong ,  Stephanie Shaw ,  Yung-hyo Koh

    发明人： Jean-Luc Girardet ,  Zhi Hong ,  Stephanie Shaw ,  Yung-hyo Koh

    IPC分类号： C07D495/04 ,  A61K31/519 ,  A61P31/18

    CPC分类号： C07D495/04

    摘要： This application concerns certain 4-cyanophenylamino-substituted bicyclic heterocycles of formula I where the dashed line represents a double bond that may be located either between A and C(V) or between C(V) and D, where A is S or C(Z); D is S or C(W); provided that one and only one of A and D is S; where T is NH, O, or S; and where other substituents are defined herein. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.

    摘要翻译： 本申请涉及式I的某些4-氰基苯基氨基取代的双环杂环，其中虚线表示可以位于A和C（V）之间或C（V）和D之间的双键，其中A是S或C（ Z）; D为S或C（W）; A和D中只有一个是S; 其中T是NH，O或S; 并且其中其它取代基在本文中定义。 这些化合物是非核苷逆转录酶抑制剂，具有抗HIV治疗的潜力。

    Substituted thieno[3,2-D]pyrimidines as HIV inhibitors
    5.
    发明授权
    Substituted thieno[3,2-D]pyrimidines as HIV inhibitors 失效
    取代噻吩并[3,2-D]嘧啶作为HIV抑制剂

    公开(公告)号：US07595324B2

    公开(公告)日：2009-09-29

    申请号：US11938101

    申请日：2007-11-09

    申请人： Jean-Luc Girardet ,  Zhi Hong ,  Stephanie Shaw ,  Yung-hyo Koh

    发明人： Jean-Luc Girardet ,  Zhi Hong ,  Stephanie Shaw ,  Yung-hyo Koh

    IPC分类号： C07D495/04 ,  C07D403/12 ,  A61K31/502 ,  A61K31/519 ,  A61P31/14

    CPC分类号： C07D495/04

    摘要： This application concerns certain 4-cyanophenylamino-substituted bicyclic heterocycles of formula I where the dashed line represents a double bond that may be located either between A and C(V) or between C(V) and D, where A is S or C(Z); D is S or C(W); provided that one and only one of A and D is S; where T is NH, O, or S; and where other substituents are defined herein. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.

    摘要翻译： 本申请涉及式I的某些4-氰基苯基氨基取代的双环杂环，其中虚线表示可以位于A和C（V）之间或C（V）和D之间的双键，其中A是S或C（ Z）; D为S或C（W）; A和D中只有一个是S; 其中T是NH，O或S; 并且其中其它取代基在本文中定义。 这些化合物是非核苷逆转录酶抑制剂，具有抗HIV治疗的潜力。

    4-CYANOPHENYLAMINO-SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS HIV INHIBITORS
    6.
    发明申请
    4-CYANOPHENYLAMINO-SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS HIV INHIBITORS 失效
    作为艾滋病毒抗体的4-氰基亚氨基取代的双环杂环化合物

    公开(公告)号：US20080176871A1

    公开(公告)日：2008-07-24

    申请号：US11938101

    申请日：2007-11-09

    申请人： Jean-Luc Girardet ,  Zhi Hong ,  Stephanie Shaw ,  Yung-hyo Koh

    发明人： Jean-Luc Girardet ,  Zhi Hong ,  Stephanie Shaw ,  Yung-hyo Koh

    IPC分类号： A61K31/519 ,  C07D519/00 ,  A61P31/12

    CPC分类号： C07D495/04

    摘要： This application concerns certain 4-cyanophenylamino-substituted bicyclic heterocycles of formula I where the dashed line represents a double bond that may be located either between A and C(V) or between C(V) and D, where A is S or C(Z); D is S or C(W); provided that one and only one of A and D is S; where T is NH, O, or S; and where other substituents are defined herein. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.

    摘要翻译： 本申请涉及式I的某些4-氰基苯基氨基取代的双环杂环，其中虚线表示可以位于A和C（V）之间或C（V）和D之间的双键，其中A是S或C（ Z）; D为S或C（W）; A和D中只有一个是S; 其中T是NH，O或S; 并且其中其它取代基在本文中定义。 这些化合物是非核苷逆转录酶抑制剂，具有抗HIV治疗的潜力。