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1.发明授权公开(公告)号：US08939991B2
公开(公告)日：2015-01-27
申请号：US12480664
申请日：2009-06-08
IPC分类号： A61B17/221 , A61B17/32 , A61B17/3207 , A61M25/00 , A61M25/04 , A61M25/09 , A61B17/3205 , A61B17/22 , A61M25/10
CPC分类号： A61B17/221 , A61B17/32056 , A61B17/3207 , A61B2017/00778 , A61B2017/22079 , A61B2017/2217 , A61B2017/320064 , A61B2017/320775 , A61B2217/005 , A61M25/0068 , A61M25/0074 , A61M25/0082 , A61M25/04 , A61M25/09 , A61M25/10 , A61M2025/0096 , A61M2025/09175 , A61M2025/09183 , A61M2025/1052
摘要： An apparatus is provided for removing material within a body lumen that includes a catheter including a proximal end, a distal end for introduction into a body lumen, and an aspiration lumen extending therebetween; a guide member extending from the distal end and terminating in a distal tip, the guide member comprising a track adjacent a track lumen extending from the distal tip into the aspiration lumen; and an obstruction clearing device deployable from the guide member and retractable along the track. In addition or alternatively, the apparatus includes a cutting head reciprocable within the aspiration lumen adjacent the distal end for macerating material being aspirated into the aspiration lumen.
摘要翻译： 提供了一种用于去除体腔内的材料的装置，其包括导管，其包括近端，用于引入体腔的远端和在其间延伸的抽吸腔; 引导构件，其从所述远端延伸并且终止于远侧末端，所述引导构件包括邻近从所述远端延伸到所述抽吸腔内的轨道腔的轨道; 以及阻挡物清除装置，其可从引导构件展开并沿着轨道缩回。 另外或替代地，所述设备包括切割头，所述切割头可在靠近所述远端的所述抽吸腔内往复运动，用于浸没材料被吸入所述抽吸腔。
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公开(公告)号：US08043313B2
公开(公告)日：2011-10-25
申请号：US12497135
申请日：2009-07-02
IPC分类号： A61B17/3207
CPC分类号： A61M25/104 , A61B17/22032 , A61B17/221 , A61B17/32056 , A61B17/320725 , A61B2017/22034 , A61B2017/22061 , A61B2017/2212 , A61B2017/2215 , A61M25/0075 , A61M25/0097 , A61M25/10 , A61M25/1011 , A61M2025/0008 , A61M2025/1068 , A61M2025/1077 , A61M2025/1084 , A61M2025/1086 , A61M2025/109
摘要： An apparatus is provided that is operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including a proximal end, a distal end, a lumen extending therebetween, and a balloon on the distal end having an interior communicating with the lumen. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The apparatus also includes an actuator for axially compressing the balloon, and a helical member extends between ends of the balloon interior that expands the balloon from a contracted condition to an expanded helical shape when the actuator is activated.
摘要翻译： 提供一种能够以不同模式操作以执行用于治疗体腔的各种功能的装置。 所述装置包括轴，所述轴包括近端，远端，在其间延伸的内腔，以及远端上的气囊，其具有与内腔连通的内部。 该装置包括在远端上的选择性地打开或关闭与内腔连通的出口的阀。 当阀门打开时，引入管腔的流体将出口排出到体腔内。 随着阀关闭，引入内腔的流体膨胀气囊。 该装置还包括用于轴向压缩气囊的致动器，并且螺旋构件在球囊内部的端部之间延伸，当致动器被致动时，气囊从收缩状态膨胀到扩张的螺旋形状。
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公开(公告)号：US08945160B2
公开(公告)日：2015-02-03
申请号：US12843004
申请日：2010-07-23
申请人： Jeffrey A. Krolik , Gwendolyn Watanabe , Juan Domingo , Ray Betelia , James H. Dreher , Daryush Mirzaee , Lucas Fernandez
发明人： Jeffrey A. Krolik , Gwendolyn Watanabe , Juan Domingo , Ray Betelia , James H. Dreher , Daryush Mirzaee , Lucas Fernandez
IPC分类号： A61M25/10 , A61B17/22 , A61B17/221 , A61B17/3207 , A61F2/958 , A61B17/3205 , A61M25/00
CPC分类号： A61M25/10185 , A61B17/22032 , A61B17/221 , A61B17/32056 , A61B17/320725 , A61B2017/22034 , A61B2017/22061 , A61B2017/22082 , A61B2017/2212 , A61B2017/2215 , A61F2/958 , A61M25/0075 , A61M25/0097 , A61M25/10 , A61M25/1002 , A61M25/1011 , A61M25/104 , A61M29/02 , A61M2025/0008 , A61M2025/1068 , A61M2025/1077 , A61M2025/1084 , A61M2025/1086 , A61M2025/109
摘要： An apparatus is provided that is operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including proximal and distal ends, a lumen extending therebetween, and a balloon on the distal end. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The valve may be biased to be closed, e.g., by a spring element disposed within the balloon. Optionally, the apparatus also includes an actuator for expanding a helical member within the balloon interior, e.g., either before or after expanding the balloon, such that the helical member and balloon may adopt an expanded helical shape for removing material within a body lumen.
摘要翻译： 提供一种能够以不同模式操作以执行用于治疗体腔的各种功能的装置。 该装置包括轴，该轴包括近端和远端，在其间延伸的内腔和远端上的气囊。 该装置包括在远端上的选择性地打开或关闭与内腔连通的出口的阀。 当阀门打开时，引入管腔的流体将出口排出到体腔内。 随着阀关闭，引入内腔的流体膨胀气囊。 阀可以被偏置为关闭，例如通过设置在气囊内的弹簧元件来关闭。 可选地，该装置还包括用于在球囊内部扩张螺旋构件的致动器，例如在膨胀囊之前或之后，使得螺旋构件和球囊可采用扩展的螺旋形状以去除体腔内的材料。
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公开(公告)号：US20110125132A1
公开(公告)日：2011-05-26
申请号：US12843004
申请日：2010-07-23
申请人： Jeffrey A. Krolik , Gwendolyn Watanabe , Juan Domingo , Ray Betelia , James H. Dreher , Daryush Mirzaee , Lucas Fernandez
发明人： Jeffrey A. Krolik , Gwendolyn Watanabe , Juan Domingo , Ray Betelia , James H. Dreher , Daryush Mirzaee , Lucas Fernandez
CPC分类号： A61M25/10185 , A61B17/22032 , A61B17/221 , A61B17/32056 , A61B17/320725 , A61B2017/22034 , A61B2017/22061 , A61B2017/22082 , A61B2017/2212 , A61B2017/2215 , A61F2/958 , A61M25/0075 , A61M25/0097 , A61M25/10 , A61M25/1002 , A61M25/1011 , A61M25/104 , A61M29/02 , A61M2025/0008 , A61M2025/1068 , A61M2025/1077 , A61M2025/1084 , A61M2025/1086 , A61M2025/109
摘要： An apparatus is provided that is operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including proximal and distal ends, a lumen extending therebetween, and a balloon on the distal end. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The valve may be biased to be closed, e.g., by a spring element disposed within the balloon. Optionally, the apparatus also includes an actuator for expanding a helical member within the balloon interior, e.g., either before or after expanding the balloon, such that the helical member and balloon may adopt an expanded helical shape for removing material within a body lumen.
摘要翻译： 提供一种能够以不同模式操作以执行用于治疗体腔的各种功能的装置。 该装置包括轴，该轴包括近端和远端，在其间延伸的内腔和远端上的气囊。 该装置包括在远端上的选择性地打开或关闭与内腔连通的出口的阀。 当阀门打开时，引入管腔的流体将出口排出到体腔内。 随着阀关闭，引入内腔的流体膨胀气囊。 阀可以被偏置为关闭，例如通过设置在气囊内的弹簧元件来关闭。 可选地，该装置还包括用于在球囊内部扩张螺旋构件的致动器，例如在膨胀囊之前或之后，使得螺旋构件和球囊可采用扩展的螺旋形状以去除体腔内的材料。
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公开(公告)号：US20130289589A1
公开(公告)日：2013-10-31
申请号：US13655688
申请日：2012-10-19
IPC分类号： A61B17/3207
CPC分类号： A61B17/3207 , A61B17/221 , A61B17/320725 , A61B2017/00867 , A61B2017/22067 , A61B2017/22069 , A61B2017/22079 , A61B2017/2215 , A61B2017/320741
摘要： Apparatus and methods are provided for removing obstructive material within a body lumen. The apparatus includes a macerator device deployable from a sheath that includes an expandable cage carried by a shaft and within a constraint tube. The shaft is movable relative to the constraint tube for deploying and expanding the cage within a body lumen such that an open end of the cage is oriented towards obstructive material. The cage is advanced to capture the material or the material is directed into the cage using an expandable member expanded beyond the material and retracted to direct the material into the cage. The cage is withdrawn into the constraint tube to compress the cage radially inwardly. Materials extending through apertures in the cage are sheared off by a sharpened edge of the constraint tube. The smaller, sheared off particles are then aspirated from the body lumen through the sheath.
摘要翻译： 提供了用于去除体腔内的阻塞物质的装置和方法。 该装置包括可从护套展开的剥离器装置，其包括由轴承载并在约束管内的可膨胀笼。 轴可相对于约束管移动，用于在笼体内展开和膨胀保持架，使得保持架的开口端朝向阻塞物质。 保持架被推进以捕获材料，或者材料被引导到保持架中，使用膨胀材料膨胀超过材料并缩回以将材料引导到保持架中。 将笼子拉出到约束管中，以径向向内压缩笼。 延伸通过保持架中的孔的材料被约束管的锋利边缘剪切掉。 然后通过护套从体腔吸出较小的剪切颗粒。
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公开(公告)号：US08298252B2
公开(公告)日：2012-10-30
申请号：US12564892
申请日：2009-09-22
IPC分类号： A61F2/01 , A61B17/221
CPC分类号： A61B17/3207 , A61B17/221 , A61B17/320725 , A61B2017/00867 , A61B2017/22067 , A61B2017/22069 , A61B2017/22079 , A61B2017/2215 , A61B2017/320741
摘要： Apparatus and methods are provided for removing obstructive material within a body lumen. The apparatus includes a macerator device deployable from a sheath that includes an expandable cage carried by a shaft and within a constraint tube. The shaft is movable relative to the constraint tube for deploying and expanding the cage within a body lumen such that an open end of the cage is oriented towards obstructive material. The cage is advanced to capture the material or the material is directed into the cage using an expandable member expanded beyond the material and retracted to direct the material into the cage. The cage is withdrawn into the constraint tube to compress the cage radially inwardly. Material extending through apertures in the cage are sheared off by a sharpened edge of the constraint tube. The smaller, sheared off particles are then aspirated from the body lumen through the sheath.
摘要翻译： 提供了用于去除体腔内的阻塞物质的装置和方法。 该装置包括可从护套展开的剥离器装置，其包括由轴承载并在约束管内的可膨胀笼。 轴可相对于约束管移动，用于在笼体内展开和膨胀笼，使得保持架的开口端朝向阻塞物质。 保持架被推进以捕获材料，或者材料被引导到保持架中，使用膨胀材料膨胀超过材料并缩回以将材料引导到保持架中。 将笼子拉出到约束管中，以径向向内压缩笼。 延伸通过保持架中的孔的材料被约束管的锋利边缘剪切掉。 然后通过护套从体腔吸出较小的剪切颗粒。
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公开(公告)号：US20100137892A1
公开(公告)日：2010-06-03
申请号：US12564892
申请日：2009-09-22
CPC分类号： A61B17/3207 , A61B17/221 , A61B17/320725 , A61B2017/00867 , A61B2017/22067 , A61B2017/22069 , A61B2017/22079 , A61B2017/2215 , A61B2017/320741
摘要： Apparatus and methods are provided for removing obstructive material within a body lumen. The apparatus includes a macerator device deployable from a sheath that includes an expandable cage carried by a shaft and within a constraint tube. The shaft is movable relative to the constraint tube for deploying and expanding the cage within a body lumen such that an open end of the cage is oriented towards obstructive material. The cage is advanced to capture the material or the material is directed into the cage using an expandable member expanded beyond the material and retracted to direct the material into the cage. The cage is withdrawn into the constraint tube to compress the cage radially inwardly. Material extending through apertures in the cage are sheared off by a sharpened edge of the constraint tube. The smaller, sheared off particles are then aspirated from the body lumen through the sheath.
摘要翻译： 提供了用于去除体腔内的阻塞物质的装置和方法。 该装置包括可从护套展开的剥离器装置，其包括由轴承载并在约束管内的可膨胀笼。 轴可相对于约束管移动，用于在笼体内展开和膨胀保持架，使得保持架的开口端朝向阻塞物质。 保持架被推进以捕获材料，或者材料被引导到保持架中，使用膨胀材料膨胀超过材料并缩回以将材料引导到保持架中。 将笼子拉出到约束管中，以径向向内压缩笼。 延伸通过保持架中的孔的材料被约束管的锋利边缘剪切掉。 然后通过护套从体腔吸出较小的剪切颗粒。
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公开(公告)号：US20100036410A1
公开(公告)日：2010-02-11
申请号：US12497135
申请日：2009-07-02
IPC分类号： A61M25/10
CPC分类号： A61M25/104 , A61B17/22032 , A61B17/221 , A61B17/32056 , A61B17/320725 , A61B2017/22034 , A61B2017/22061 , A61B2017/2212 , A61B2017/2215 , A61M25/0075 , A61M25/0097 , A61M25/10 , A61M25/1011 , A61M2025/0008 , A61M2025/1068 , A61M2025/1077 , A61M2025/1084 , A61M2025/1086 , A61M2025/109
摘要： An apparatus is provided that is operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including a proximal end, a distal end, a lumen extending therebetween, and a balloon on the distal end having an interior communicating with the lumen. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The apparatus also includes an actuator for axially compressing the balloon, and a helical member extends between ends of the balloon interior that expands the balloon from a contracted condition to an expanded helical shape when the actuator is activated.
摘要翻译： 提供一种能够以不同模式操作以执行用于治疗体腔的各种功能的装置。 所述装置包括轴，所述轴包括近端，远端，在其间延伸的内腔，以及远端上的球囊，其具有与内腔连通的内部。 该装置包括在远端上的选择性地打开或关闭与内腔连通的出口的阀。 当阀门打开时，引入管腔的流体将出口排出到体腔内。 随着阀关闭，引入内腔的流体膨胀气囊。 该装置还包括用于轴向压缩气囊的致动器，并且螺旋构件在气囊内部的端部之间延伸，当致动器被致动时，气囊从收缩状态膨胀成扩张的螺旋形状。
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9.发明申请公开(公告)号：US20100036312A1
公开(公告)日：2010-02-11
申请号：US12480664
申请日：2009-06-08
IPC分类号： A61B17/221 , A61M29/02 , A61M1/00
CPC分类号： A61B17/221 , A61B17/32056 , A61B17/3207 , A61B2017/00778 , A61B2017/22079 , A61B2017/2217 , A61B2017/320064 , A61B2017/320775 , A61B2217/005 , A61M25/0068 , A61M25/0074 , A61M25/0082 , A61M25/04 , A61M25/09 , A61M25/10 , A61M2025/0096 , A61M2025/09175 , A61M2025/09183 , A61M2025/1052
摘要： An apparatus is provided for removing material within a body lumen that includes a catheter including a proximal end, a distal end for introduction into a body lumen, and an aspiration lumen extending therebetween; a guide member extending from the distal end and terminating in a distal tip, the guide member comprising a track adjacent a track lumen extending from the distal tip into the aspiration lumen; and an obstruction clearing device deployable from the guide member and retractable along the track. In addition or alternatively, the apparatus includes a cutting head reciprocable within the aspiration lumen adjacent the distal end for macerating material being aspirated into the aspiration lumen.
摘要翻译： 提供了一种用于去除体腔内的材料的装置，其包括导管，其包括近端，用于引入体腔的远端和在其间延伸的抽吸腔; 引导构件，其从所述远端延伸并且终止于远侧末端，所述引导构件包括邻近从所述远端延伸到所述抽吸腔内的轨道腔的轨道; 以及阻挡物清除装置，其可从引导构件展开并沿着轨道缩回。 另外或替代地，所述设备包括切割头，所述切割头可在靠近所述远端的所述抽吸腔内往复运动，用于浸没材料被吸入所述抽吸腔。
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公开(公告)号：US09492263B2
公开(公告)日：2016-11-15
申请号：US12746920
申请日：2008-12-10
IPC分类号： A61M29/00 , A61F2/01 , A61B17/221 , A61B17/22
CPC分类号： A61B17/221 , A61B2017/00862 , A61B2017/22035 , A61B2017/22038 , A61B2017/2212 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0069 , A61M1/3655
摘要： An apparatus for capturing material within a body lumen includes a shaft carrying an expandable basket device on a distal end thereof. The basket device includes a distal basket carried and a proximal basket carried on the shaft such that the proximal basket is proximal to and spaced apart from the distal basket. Each basket includes an open end communicating with an interior of the respective basket and oriented towards one another. In one embodiment, a tubular middle portion extends between the baskets. In another embodiment, the distal basket includes an actuator coupled to the distal basket open end such that movement of the baskets towards one another causes the actuator to direct the distal basket open end inwardly to allow the open end to be received within the proximal basket to facilitate removal of the apparatus after capturing material within the baskets.
摘要翻译： 用于在体腔内捕获材料的装置包括在其远端承载可膨胀篮装置的轴。 篮子装置包括承载的远侧篮子和承载在轴上的近侧篮，使得近侧篮子靠近并与远侧篮子间隔开。 每个篮子包括与相应篮子的内部相通并且朝向彼此定向的开放端。 在一个实施例中，管状中间部分在篮子之间延伸。 在另一个实施例中，远侧筐包括联接到远侧筐开口端的致动器，使得篮子朝向彼此的移动导致致动器将远侧筐开放端向内引导，以允许开放端被容纳在近侧筐内 便于在筐内捕获材料之后移除设备。
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