公开(公告)号：US20060160242A1

公开(公告)日：2006-07-20

申请号：US10564697

申请日：2004-07-08

申请人： Jens Jensen ,  Joseph Helpern ,  Glyn Johnson ,  Ramesh Chandra

发明人： Jens Jensen ,  Joseph Helpern ,  Glyn Johnson ,  Ramesh Chandra

IPC分类号： G01N24/00

CPC分类号： G01R33/50 ,  G01R33/56341 ,  G01R33/56536 ,  Y10T436/24

摘要： Methods, systems, software arrangements and storage medium for measuring the magnetic field correlation function (“MFC”), and more particularly, to methods for measuring the magnetic field correlation function utilizing asymmetric spin echoes. Asymmetric Dual Spin Echo Sequences (“ADSE”) and Echo Planar Imaging Asymmetric Dual Spin Echo Sequences (“EPI-ADSE”) may be employed to apply multiple echoes to a sample and acquire data from which the MFC may be determined.

摘要翻译： 用于测量磁场相关函数（“MFC”）的方法，系统，软件布置和存储介质，更具体地说，涉及利用非对称自旋回波测量磁场相关函数的方法。 可以采用非对称双自旋回波序列（“ADSE”）和回波平面成像不对称双自旋回波序列（“EPI-ADSE”）将多个回波应用于样本，并获取可以确定MFC的数据。

公开(公告)号：US20100207626A1

公开(公告)日：2010-08-19

申请号：US12710035

申请日：2010-02-22

申请人： Jens Jensen ,  Joseph A. Helpern ,  Glyn Johnson ,  Ramesh Chandra

发明人： Jens Jensen ,  Joseph A. Helpern ,  Glyn Johnson ,  Ramesh Chandra

IPC分类号： G01R33/44

CPC分类号： G01R33/50 ,  G01R33/56341 ,  G01R33/56536 ,  Y10T436/24

摘要： Methods, systems, software arrangements and storage medium for measuring the magnetic field correlation function (“MFC”), and more particularly, to methods for measuring the magnetic field correlation function utilizing asymmetric spin echoes. Asymmetric Dual Spin Echo Sequences (“ADSE”) and Echo Planar Imaging Asymmetric Dual Spin Echo Sequences (“EPI-ADSE”) may be employed to apply multiple echoes to a sample and acquire data from which the MFC may be determined.

摘要翻译： 用于测量磁场相关函数（“MFC”）的方法，系统，软件布置和存储介质，更具体地说，涉及利用非对称自旋回波测量磁场相关函数的方法。 可以采用非对称双自旋回波序列（“ADSE”）和回波平面成像不对称双自旋回波序列（“EPI-ADSE”）将多个回波应用于样本，并获取可以确定MFC的数据。

公开(公告)号：US07852078B2

公开(公告)日：2010-12-14

申请号：US12710035

申请日：2010-02-22

申请人： Jens Jensen ,  Joseph A. Helpern ,  Glyn Johnson ,  Ramesh Chandra

发明人： Jens Jensen ,  Joseph A. Helpern ,  Glyn Johnson ,  Ramesh Chandra

IPC分类号： G01V3/00

CPC分类号： G01R33/50 ,  G01R33/56341 ,  G01R33/56536 ,  Y10T436/24

摘要： Methods, systems, software arrangements and storage medium for measuring the magnetic field correlation function (“MFC”), and more particularly, to methods for measuring the magnetic field correlation function utilizing asymmetric spin echoes. Asymmetric Dual Spin Echo Sequences (“ADSE”) and Echo Planar Imaging Asymmetric Dual Spin Echo Sequences (“EPI-ADSE”) may be employed to apply multiple echoes to a sample and acquire data from which the MFC may be determined.

摘要翻译： 用于测量磁场相关函数（“MFC”）的方法，系统，软件布置和存储介质，更具体地说，涉及利用非对称自旋回波测量磁场相关函数的方法。 可以采用非对称双自旋回波序列（“ADSE”）和回波平面成像不对称双自旋回波序列（“EPI-ADSE”）将多个回波应用于样本，并获取可以确定MFC的数据。

公开(公告)号：US07667459B2

公开(公告)日：2010-02-23

申请号：US10564697

申请日：2004-07-08

申请人： Jens Jensen ,  Joseph A. Helpern ,  Glyn Johnson ,  Ramesh Chandra

发明人： Jens Jensen ,  Joseph A. Helpern ,  Glyn Johnson ,  Ramesh Chandra

IPC分类号： G01V3/00

CPC分类号： G01R33/50 ,  G01R33/56341 ,  G01R33/56536 ,  Y10T436/24

摘要： Methods, systems, software arrangements and storage medium for measuring the magnetic field correlation function (“MFC”), and more particularly, to methods for measuring the magnetic field correlation function utilizing asymmetric spin echoes. Asymmetric Dual Spin Echo Sequences (“ADSE”) and Echo Planar Imaging Asymmetric Dual Spin Echo Sequences (“EPI-ADSE”) may be employed to apply multiple echoes to a sample and acquire data from which the MFC may be determined.

摘要翻译： 用于测量磁场相关函数（“MFC”）的方法，系统，软件布置和存储介质，更具体地说，涉及利用非对称自旋回波测量磁场相关函数的方法。 可以采用非对称双自旋回波序列（“ADSE”）和回波平面成像不对称双自旋回波序列（“EPI-ADSE”）将多个回波应用于样本，并获取可以确定MFC的数据。

公开(公告)号：US4506222A

公开(公告)日：1985-03-19

申请号：US320953

申请日：1981-11-09

申请人： William A. Edelstein ,  James M. S. Hutchison ,  Glyn Johnson ,  Thomas W. T. Redpath ,  John R. Mallard

发明人： William A. Edelstein ,  James M. S. Hutchison ,  Glyn Johnson ,  Thomas W. T. Redpath ,  John R. Mallard

IPC分类号： A61B5/055 ,  A61B10/00 ,  G01R33/48 ,  G01R33/54 ,  G01R33/561 ,  G01R33/08

CPC分类号： G01R33/482 ,  G01R33/5615 ,  G01R33/5616

摘要： To produce image information from an object it is subjected to a continuous static magnetic field along a Z axis and to sets of sequences of orthogonal gradients G.sub.x, G.sub.y and G.sub.z to the magnetic field. Spins in a selected plane (the X-Z plane) are excited by selective rf pulses and an associated G.sub.y gradient and the selected spins are subjected to all three gradients of which the G.sub.z gradient provides twist or warp to each column of spins extending along the Z axis to phase-encode the columns. The spin-echo signals are read out in the presence of a G.sub.x gradient. In each set of sequences a different value of Z gradient is employed. The Fourier transformed spin-echo signals obtained from each sequence, when arranged in order of increasing G.sub.z gradient and subjected to a second Fourier transform represent the distribution of spin density in the Z direction, thus giving a two-dimensional image of the selected X-Z plane.

公开(公告)号：US4706025A

公开(公告)日：1987-11-10

申请号：US879419

申请日：1986-06-27

申请人： William A. Edelstein ,  James M. S. Hutchison ,  Glyn Johnson ,  Thomas W. T. Redpath ,  John R. Mallard

发明人： William A. Edelstein ,  James M. S. Hutchison ,  Glyn Johnson ,  Thomas W. T. Redpath ,  John R. Mallard

IPC分类号： G01R33/54 ,  G01R33/561 ,  G01R33/20

CPC分类号： G01R33/482 ,  G01R33/5615 ,  G01R33/5616

摘要： To produce image information from an object it is subjected to a continuous static magnetic field along a Z axis and to sets of sequences of orthogonal gradients G.sub.x, G.sub.y and G.sub.z to the magnetic field. Spins in a selected plane (the X-Z plane) are excited by selective rf pulses and an associated G.sub.y gradient and the selected spins are subjected to all three gradients of which the G.sub.z gradient provides twist or warp to each column of spins extending along the Z axis to phase-encode the columns. The spin-echo signals are read out in the presence of a G.sub.x gradient. In each set of sequences a different value of Z gradient is employed. The Fourier transformed spin-echo signals obtained from each sequence, when arranged in order of increasing G.sub.z gradient and subjected to a second Fourier transform represent the distribution of spin density in the Z direction, thus giving a two-dimensional image of the selected X-Z plane.

摘要翻译： 为了从物体产生图像信息，它沿着Z轴进行连续的静态磁场，并且将正交梯度Gx，Gy和Gz的序列的集合施加到磁场。 所选择的平面（XZ平面）中的自旋被选择性射频脉冲和相关联的Gy梯度激发，并且所选择的旋转经受所有三个梯度，其中Gz梯度向沿Z轴延伸的每个旋转列提供扭曲或翘曲 对列进行相位编码。 在存在Gx梯度的情况下读出自旋回波信号。 在每组序列中，采用不同的Z梯度值。 从每个序列获得的傅里叶变换的自旋回波信号，当按增加的Gz梯度并进行第二傅里叶变换的顺序排列时，表示Z方向上的自旋密度的分布，从而给出所选择的XZ平面的二维图像 。

公开(公告)号：US4651095A

公开(公告)日：1987-03-17

申请号：US636857

申请日：1984-08-01

申请人： Linda M. Eastwood ,  James M. S. Hutchison ,  Glyn Johnson ,  Thomas W. T. Redpath ,  Robert D. Selbie ,  John R. Mallard

发明人： Linda M. Eastwood ,  James M. S. Hutchison ,  Glyn Johnson ,  Thomas W. T. Redpath ,  Robert D. Selbie ,  John R. Mallard

IPC分类号： A61B10/00 ,  A61B5/055 ,  G01R33/32 ,  G01R33/48 ,  G01R33/54 ,  G01R33/20

CPC分类号： G01R33/482

摘要： A set of NMR free induction signals generated in nuclei in a sample are recorded in the presence of a magnetic field gradient to a static magnetic field in which the sample is positioned. Prior to recording a magnetic field gradient orthogonal to the said gradient is applied to phase-encode the signals. The individual signals of a set are differentiated by being recorded after different time integrals of the phase encoding gradient. The magnitudes of successive time integrals have a non-monotonic relationship with each other so that sufficient signal data is recorded to enable the Fourier transform operation to commence before half or less of the set of signals has been recorded. Preferably the relationship between the magnitudes of successive time integrals corresponds to a numerical sequence represented by a monotonic sequence of binary numbers re-arranged in bit-reversed order.

摘要翻译： 在存在磁场梯度的情况下，将样品中的核中产生的一组NMR自由感应信号记录到样品所在的静态磁场。 在记录之前，将与所述梯度正交的磁场梯度应用于信号的相位编码。 通过在相位编码梯度的不同时间积分之后被记录来区分集合的各个信号。 连续时间积分的大小彼此之间具有非单调关系，从而记录足够的信号数据，以使傅里叶变换操作在已经记录了该组信号的一半以下之前开始。 优选地，连续时间积分的大小之间的关系对应于以比特反转顺序重新排列的二进制数的单调序列表示的数字序列。

公开(公告)号：US4607223A

公开(公告)日：1986-08-19

申请号：US520231

申请日：1983-08-04

申请人： John R. Mallard ,  Glyn Johnson ,  Linda M. Eastwood ,  Thomas W. T. Redpath ,  James M. S. Hutchison

发明人： John R. Mallard ,  Glyn Johnson ,  Linda M. Eastwood ,  Thomas W. T. Redpath ,  James M. S. Hutchison

IPC分类号： A61B10/00 ,  A61B5/055 ,  G01R33/48 ,  G01R33/54 ,  G01R33/561 ,  G01N24/08

CPC分类号： G01R33/4822 ,  G01R33/5616

摘要： A method of deriving three dimensional image information from an object using nuclear magnetic resonance signals is described. The method comprises subjecting the object to a continuous, static magnetic field and carrying out the following set of sequential steps.1. Exciting nuclear spins in a volume;2. applying non-aligned first, second and third gradients of the magnetic field;3. causing the spins to rephase periodically in the presence of the first gradient;4. phase encoding the spins in the direction of the second gradient prior to every read-out of the rephased FIS from the object;and then successively repeating the above set of steps with different values of gradient of the third gradient (G.sub.z.sup.(2)), there being a recovery interval between the repetition of successive sets of steps.

摘要翻译： 描述了使用核磁共振信号从对象导出三维图像信息的方法。 该方法包括使物体经受连续的静态磁场并执行以下一组顺序步骤。 激动的核旋转在一个卷; 2.应用磁场的非对准的第一，第二和第三梯度; 3.在第一梯度的存在下，使自旋重新定型; 4.在从对象中读出已重定位的FIS之前，在第二梯度的方向上相位编码自旋; 然后用不同的第三梯度（Gz（2））的梯度连续地重复上述步骤，在重复连续的步骤组之间存在恢复间隔。

公开(公告)号：US4602214A

公开(公告)日：1986-07-22

申请号：US702126

申请日：1985-02-15

申请人： William A. Edelstein ,  James M. S. Hutchison ,  Glyn Johnson ,  Thomas W. T. Redpath ,  John R. Mallard

发明人： William A. Edelstein ,  James M. S. Hutchison ,  Glyn Johnson ,  Thomas W. T. Redpath ,  John R. Mallard

IPC分类号： A61B5/055 ,  A61B10/00 ,  G01R33/48 ,  G01R33/54 ,  G01R33/561 ,  G01R33/20

CPC分类号： G01R33/482 ,  G01R33/5615 ,  G01R33/5616

摘要： To produce image information from an object it is subjected to a continuous static magnetic field along a Z axis to sets of sequences of orthogonal gradients G.sub.x, G.sub.y and G.sub.z to the magnetic field. Spins in a selected plane (the X-Z plane) are excited by selective rf pulses and an associated G.sub.y gradient and the selected spins are subjected to all three gradients of which the G.sub.z gradient provides twist or warp to each column of spins extending along the Z axis to phase-encode the columns. The spin-echo signals are read out in the presence of a G.sub.x gradient. In each set of sequences a different value of Z gradient is employed. The Fourier transformed spin-echo signals obtained from each sequence, when arranged in order of increasing G.sub.z gradient and subjected to a second Fourier transform represent the distribution of spin density in the Z direction, thus giving a two-dimensional image of the selected X-Z plane.

公开(公告)号：US4451788A

公开(公告)日：1984-05-29

申请号：US320951

申请日：1981-11-09

申请人： William A. Edelstein ,  James M. S. Hutchison ,  Glyn Johnson ,  Thomas W. T. Redpath ,  John R. Mallard

发明人： William A. Edelstein ,  James M. S. Hutchison ,  Glyn Johnson ,  Thomas W. T. Redpath ,  John R. Mallard

IPC分类号： A61B5/055 ,  A61B10/00 ,  G01R33/48 ,  G01R33/54 ,  G01R33/561 ,  G01R33/08

CPC分类号： G01R33/482 ,  G01R33/5615 ,  G01R33/5616

摘要： To produce image information from an object it is subjected to a continuous static magnetic field along a Z axis and to sets of sequences of gradient G.sub.x, G.sub.y and G.sub.z to the magnetic field. Spins in a selected plane (the X-Z plane) are excited by selective rf pulses and an associated G.sub.y gradient and the selected spins are subjected to a reversed G.sub.y gradient together with a G.sub.x gradient. The G.sub.y gradient is then switched off and the direction of the G.sub.x gradient is then repeatedly reversed. During the action of reversal of the G.sub.x gradient a small G.sub.z gradient is provided. Each reversed G.sub.x gradient is held constant for a sufficient time for a free induction decay signal to be generated thus providing a multiple echo of the spins in the selected plane. Alternate signals are time-reversed and then both the time-reversed and non time-reversed signals are subject to Fourier transformation.

摘要翻译： PCT No.PCT / GB81 / 00045 Sec。 371日期1981年11月9日 102（e）日期1981年11月9日PCT提交1981年3月13日PCT公布。 出版物WO81 / 02789 日期为1981年10月1日。为了从物体产生图像信息，它沿着Z轴进行连续的静态磁场以及梯度Gx，Gy和Gz的序列集合到磁场。 在选定的平面（X-Z平面）中的自旋由选择性rf脉冲和相关联的Gy梯度激发，并且所选择的旋转与Gx梯度一起经受反转的Gy梯度。 然后关闭Gy梯度，然后重复反转Gx梯度的方向。 在Gx梯度反转的作用下，提供了一个小的Gz梯度。 每个反转的Gx梯度保持恒定足够的时间以产生自由感应衰减信号，从而在所选择的平面中提供自旋的多个回波。 交替信号是时间反转的，然后时间反转信号和非时间反相信号都经过傅里叶变换。