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公开(公告)号：US20050112221A1
公开(公告)日：2005-05-26
申请号：US10979896
申请日：2004-11-01
CPC分类号： A61Q19/02 , A61K8/97 , A61K36/8965
摘要： A skin whitening composition includes an extract of asparagus obtained by sequentially exposing the asparagus to two or more solvents of varying solvent strengths. The root and shoot portions of the asparagus can be separately used to obtain the extract. The composition can be topically applied to the human skin and can further include one or more cosmetically acceptable ingredients. A method of suppressing melanogenesis includes topically applying to the skin a composition comprising an extract of asparagus obtained by sequentially exposing the asparagus to two or more solvents of varying solvent strengths.
摘要翻译： 皮肤美白组合物包括通过将芦笋连续暴露于两种或更多种不同溶剂强度的溶剂而获得的芦笋提取物。 芦笋的根部和芽部分可以分别用于获得提取物。 组合物可以局部施用于人皮肤，并且还可以包括一种或多种美容上可接受的成分。 抑制黑素生成的方法包括向皮肤局部施用包含通过将芦笋连续暴露于两种或更多种不同溶剂强度的溶剂而获得的芦笋提取物的组合物。
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公开(公告)号：US20050112220A1
公开(公告)日：2005-05-26
申请号：US10979344
申请日：2004-11-01
摘要： A skin whitening composition includes an extract of black cohosh obtained by sequentially exposing the black cohosh to two or more solvents of varying solvent strengths. The root of the black cohosh can be separately used to obtain the extract. The composition can be topically applied to the human skin and can further include one or more cosmetically acceptable ingredients. A method of suppressing melanogenesis includes topically applying to the skin a composition comprising an extract of black cohosh obtained by sequentially exposing the black cohosh to two or more solvents of varying solvent strength.
摘要翻译： 皮肤美白组合物包括通过将黑色高丝顺序暴露于两种或更多种不同溶剂强度的溶剂而获得的黑色高丝提取物。 黑加索的根可以分别用于获取提取物。 组合物可以局部施用于人皮肤，并且还可以包括一种或多种美容上可接受的成分。 抑制黑素生成的方法包括向皮肤局部施用组合物，其包含通过将黑咖啡连续暴露于两种或更多种不同溶剂强度的溶剂而获得的黑色焦化提取物。
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公开(公告)号：US20070116789A1
公开(公告)日：2007-05-24
申请号：US11655015
申请日：2007-01-18
申请人： Jesse Leverett , Amitabh Chandra , Jatinder Rana , David Fast , Stephen Missler , David Flower
发明人： Jesse Leverett , Amitabh Chandra , Jatinder Rana , David Fast , Stephen Missler , David Flower
IPC分类号： A61K36/185
CPC分类号： A61K36/185 , A61K9/0014 , A61K9/08
摘要： The present invention relates to compositions comprising extracts of Durio zibethinus. The compositions of the present invention are useful for improving the appearance, texture, and/or moisture of mammalian skin. In particular, the compositions of the present invention decrease inflammation in the skin, inhibit matrix metalloprotease-9, which degrades skin proteins such as collagen and elastin, and inhibit melanogenesis in the skin.
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公开(公告)号：US20070042064A1
公开(公告)日：2007-02-22
申请号：US11208148
申请日：2005-08-19
申请人： Jesse Leverett , Amitabh Chandra , Jatinder Rana , David Fast , Stephen Missler , David Flower
发明人： Jesse Leverett , Amitabh Chandra , Jatinder Rana , David Fast , Stephen Missler , David Flower
IPC分类号： A61K36/185
CPC分类号： A61K36/185 , A61K9/0014 , A61K9/08
摘要： The present invention relates to compositions comprising extracts of Durio zibethinus. The compositions of the present invention are useful for improving the appearance, texture, and/or moisture of mammalian skin. In particular, the compositions of the present invention decrease inflammation in the skin, inhibit matrix metalloprotease-9, which degrades skin proteins such as collagen and elastin, and inhibit melanogenesis in the skin.
摘要翻译： 本发明涉及包含杜鹃（Durio zibethethus）的提取物的组合物。 本发明的组合物可用于改善哺乳动物皮肤的外观，质地和/或水分。 特别地，本发明的组合物减少皮肤的炎症，抑制基质金属蛋白酶-9，其降解皮肤蛋白质如胶原蛋白和弹性蛋白，并抑制皮肤中的黑素生成。
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公开(公告)号：US07247321B2
公开(公告)日：2007-07-24
申请号：US10979896
申请日：2004-11-01
CPC分类号： A61Q19/02 , A61K8/97 , A61K36/8965
摘要： A skin whitening composition includes an extract of asparagus obtained by sequentially exposing the asparagus to two or more solvents of varying solvent strengths. The root and shoot portions of the asparagus can be separately used to obtain the extract. The composition can be topically applied to the human skin and can further include one or more cosmetically acceptable ingredients. A method of suppressing melanogenesis includes topically applying to the skin a composition comprising an extract of asparagus obtained by sequentially exposing the asparagus to two or more solvents of varying solvent strengths.
摘要翻译： 皮肤美白组合物包括通过将芦笋连续暴露于两种或更多种不同溶剂强度的溶剂而获得的芦笋提取物。 芦笋的根部和芽部分可以分别用于获得提取物。 组合物可以局部施用于人皮肤，并且还可以包括一种或多种美容上可接受的成分。 抑制黑素生成的方法包括向皮肤局部施用包含通过将芦笋连续暴露于两种或更多种不同溶剂强度的溶剂而获得的芦笋提取物的组合物。
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公开(公告)号：US06994874B2
公开(公告)日：2006-02-07
申请号：US10417913
申请日：2003-04-16
IPC分类号： A01N65/00
CPC分类号： A61Q19/02 , A61K8/97 , A61K36/8965
摘要： A skin whitening composition includes an extract of asparagus obtained by sequentially exposing the asparagus to two or more solvents of varying solvent strengths. The root and shoot portions of the asparagus can be separately used to obtain the extract. The composition can be topically applied to the human skin and can further include one or more cosmetically acceptable ingredients. A method of suppressing melanogenesis includes topically applying to the skin a composition comprising an extract of asparagus obtained by sequentially exposing the asparagus to two or more solvents of varying solvent strengths.
摘要翻译： 皮肤美白组合物包括通过将芦笋连续暴露于两种或更多种不同溶剂强度的溶剂而获得的芦笋提取物。 芦笋的根部和芽部分可以分别用于获得提取物。 组合物可以局部施用于人皮肤，并且还可以包括一种或多种美容上可接受的成分。 抑制黑素生成的方法包括向皮肤局部施用包含通过将芦笋连续暴露于两种或更多种不同溶剂强度的溶剂而获得的芦笋提取物的组合物。
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公开(公告)号：US07364759B2
公开(公告)日：2008-04-29
申请号：US10979344
申请日：2004-11-01
摘要： A skin whitening composition includes an extract of black cohosh obtained by sequentially exposing the black cohosh to two or more solvents of varying solvent strengths. The root of the black cohosh can be separately used to obtain the extract. The composition can be topically applied to the human skin and can further include one or more cosmetically acceptable ingredients. A method of suppressing melanogenesis includes topically applying to the skin a composition comprising an extract of black cohosh obtained by sequentially exposing the black cohosh to two or more solvents of varying solvent strength.
摘要翻译： 皮肤美白组合物包括通过将黑色高丝顺序暴露于两种或更多种不同溶剂强度的溶剂而获得的黑色高丝提取物。 黑加索的根可以分别用于获取提取物。 组合物可以局部施用于人皮肤，并且还可以包括一种或多种美容上可接受的成分。 抑制黑素生成的方法包括向皮肤局部施用组合物，其包含通过将黑咖啡连续暴露于两种或更多种不同溶剂强度的溶剂而获得的黑色焦化提取物。
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公开(公告)号：US07060304B2
公开(公告)日：2006-06-13
申请号：US10417914
申请日：2003-04-16
摘要： A skin whitening composition includes an extract of black cohosh obtained by sequentially exposing the black cohosh to two or more solvents of varying solvent strengths. The root of the black cohosh can be separately used to obtain the extract. The composition can be topically applied to the human skin and can further include one or more cosmetically acceptable ingredients. A method of suppressing melanogenesis includes topically applying to the skin a composition comprising an extract of black cohosh obtained by sequentially exposing the black cohosh to two or more solvents of varying solvent strengths.
摘要翻译： 皮肤美白组合物包括通过将黑色高丝顺序暴露于两种或更多种不同溶剂强度的溶剂而获得的黑色高丝提取物。 黑加索的根可以分别用于获取提取物。 组合物可以局部施用于人皮肤，并且还可以包括一种或多种美容上可接受的成分。 抑制黑素生成的方法包括向皮肤局部施用组合物，其包含通过将黑色焦化顺序暴露于两种或更多种不同溶剂强度的溶剂而获得的黑色焦化提取物。
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9.发明申请Methods of using grape seed extract to stimulate tyrosinase expression or melanin synthesis 有权使用葡萄籽提取物刺激酪氨酸酶表达或黑色素合成的方法公开(公告)号：US20060147567A1
公开(公告)日：2006-07-06
申请号：US11300095
申请日：2005-12-14
申请人： Lane Duvel , Diego Rua , Stephen Missler , David Fast , Amitabh Chandra
发明人： Lane Duvel , Diego Rua , Stephen Missler , David Fast , Amitabh Chandra
IPC分类号： A61K36/87
CPC分类号： A61Q17/04 , A61K8/97 , A61K36/87 , A61Q5/12 , A61K2300/00
摘要： The present invention relates to methods of increasing tyrosinase synthesis, expression, or activity in a cell comprising administering at least one grape seed extract to the cell. The grape seed extract may be obtained by any extraction process including solvent sequential fractionation and supercritical fluid extraction.
摘要翻译： 本发明涉及增加细胞中酪氨酸酶合成，表达或活性的方法，包括向细胞施用至少一种葡萄籽提取物。 葡萄籽提取物可以通过任何提取方法获得，包括溶剂顺序分级和超临界流体萃取。
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公开(公告)号：US20070110831A1
公开(公告)日：2007-05-17
申请号：US11274618
申请日：2005-11-15
申请人： Chioma Ikonte , Michael Huang , Cherie Hacker , Silvia da Costa , Paul Johnson , Amitabh Chandra , Christine Paganelli , Ruo Huang
发明人： Chioma Ikonte , Michael Huang , Cherie Hacker , Silvia da Costa , Paul Johnson , Amitabh Chandra , Christine Paganelli , Ruo Huang
IPC分类号： A61K36/254 , A61K36/53 , A61K36/48 , A61K36/28 , A61K36/8965
CPC分类号： A61K36/79 , A61K36/21 , A61K36/258 , A61K36/28 , A61K36/31 , A61K36/488 , A61K36/53 , A61K36/8965 , Y10S514/893 , A61K2300/00
摘要： The present invention is directed to plant based formulations for improving liver health by protecting the liver from alcohol and chemical insults and/or by inducing phase II enzymes. Formulations according to the present invention include wasabi root fiber powder, artichoke leaf extract, asparagus dehydrate, kudzu root extract, oregano extract, schisandra berry extract, notoginseng (ethanol extract of Panax notoginseng root), sanchi (water extracts from Panax notoginseng root), Gegen root extract (Pueraria omeiensis), spinach dehydrate, or combinations thereof.
摘要翻译： 本发明涉及通过保护肝脏免受酒精和化学损伤和/或通过诱导II期酶改善肝健康的基于植物的制剂。 根据本发明的制剂包括芥子根纤维粉，朝鲜蓟叶提取物，芦笋脱水，葛根提取物，牛至提取物，五味子浆果提取物，三七（三七乙醇提取物），sanchi（三七提取物） 葛根根提取物（Pueraria omeiensis），菠菜脱水剂或其组合。
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