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公开(公告)号：US12115204B2
公开(公告)日：2024-10-15
申请号：US17790646
申请日：2021-01-05
申请人： NANTONG UNIVERSITY
发明人： Xiaosong Gu , Chunkang Tang , Fei Ding , Xiaoming Yang , Qiong Cheng , Hualin Sun , Lai Xu
IPC分类号： A61K36/481 , A61K35/583 , A61K36/076 , A61K36/21 , A61K36/232 , A61K36/284 , A61K36/286 , A61K36/64 , A61K36/725 , A61K36/815
CPC分类号： A61K36/481 , A61K35/583 , A61K36/076 , A61K36/21 , A61K36/232 , A61K36/284 , A61K36/286 , A61K36/64 , A61K36/725 , A61K36/815 , A61K2236/13 , A61K2236/331 , A61K2236/51
摘要： Disclosed are a compound preparation for neuranagenesis, and a preparation method therefor and the use thereof. The compound preparation for neuranagenesis comprises the raw medicinal materials in parts by weight: 10-20 parts of raw Astragali radix, 10-20 parts of Rehmaimiae Radix praeparata, 10-20 parts of Actyranthes bidentata, 6-15 parts of Jujubae fructus, 6-15 parts of Lycii fructus, 6-15 parts of parched Ziziphi spinosae semen, 6-12 parts of Angelicae smensis radix, 3-9 parts of Carthami flos, 6-15 parts of Poria, 6-15 parts of parched Atractylodis macrocephalae rhizoma and 10-20 parts of Zaocys. The compound preparation can be used for preparing drugs to treat nerve damage diseases, and can be prepared into oral liquids, granules, dissolved granules and tablets.
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公开(公告)号：US12076361B2
公开(公告)日：2024-09-03
申请号：US17484389
申请日：2021-09-24
申请人： SarTec Corporation
IPC分类号： A61K36/898 , A61K9/00 , A61K31/10 , A61K31/122 , A61K31/192 , A61K31/7048 , A61K36/185 , A61K36/21 , A61K36/22 , A61K36/48 , A61K36/708 , A61K36/752 , A61K36/77 , A61K36/81 , A61K36/82 , A61K36/886 , A61K36/8945 , A61K36/896 , A61K36/8962 , A61K36/8965 , A61P1/14
CPC分类号： A61K36/898 , A61K9/0056 , A61K31/10 , A61K31/122 , A61K31/192 , A61K31/7048 , A61K36/185 , A61K36/21 , A61K36/22 , A61K36/48 , A61K36/708 , A61K36/752 , A61K36/77 , A61K36/81 , A61K36/82 , A61K36/886 , A61K36/8945 , A61K36/896 , A61K36/8962 , A61K36/8965 , A61P1/14
摘要： Embodiments herein relate to compositions herein can include one or more of a tomato extract, a rhubarb extract, a garlic extract, a cashew shell composition, and a saponin composition, wherein the composition prevents or reduces methanogenesis in animals. Embodiments herein also relate to compositions including one or more of glycoalkaloids, saponins, anthraquinones, anacardic acid, and allicin and methods for using the same for mitigating methanogenesis in animals. In an embodiment, a composition can include glycoalkaloids, such as α-tomatine, that can prevent methanogenesis. In an embodiment, a method of processing animal feed is included. In an embodiment, a method of treating an animal to reduce methanogenesis is included. Other embodiments are also included herein.
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公开(公告)号：US20240261305A1
公开(公告)日：2024-08-08
申请号：US18565715
申请日：2022-06-03
发明人： Francesco Di Pierro
IPC分类号： A61K31/00 , A61K8/9789 , A61K36/21 , A61K45/06
CPC分类号： A61K31/658 , A61K8/9789 , A61K36/21 , A61K36/3482 , A61K45/06 , A61K2800/10
摘要： The invention relates to cannabinoid solutions in a mixture of sesame oil, amaranth oil and squalene. The invention also relates to pharmaceutical or nutraceutical formulations comprising said solutions.
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公开(公告)号：US11992513B2
公开(公告)日：2024-05-28
申请号：US17953859
申请日：2022-09-27
发明人： Qi Dai , Kunshan Chen , Xiaoqi Zhou
IPC分类号： A61K36/489 , A61K36/17 , A61K36/21 , A61K36/236 , A61K36/24 , A61K36/258 , A61K36/286 , A61K36/287 , A61K36/288 , A61K36/31 , A61K36/481 , A61K36/484 , A61K36/54 , A61K36/804 , A61K36/86 , A61K36/8884 , A61K36/90 , A61P17/00
CPC分类号： A61K36/489 , A61K36/17 , A61K36/21 , A61K36/236 , A61K36/24 , A61K36/258 , A61K36/286 , A61K36/287 , A61K36/288 , A61K36/31 , A61K36/481 , A61K36/484 , A61K36/54 , A61K36/804 , A61K36/86 , A61K36/8884 , A61K36/90 , A61P17/00
摘要： A traditional Chinese medicine composition for treating hand-foot syndrome after targeted drug treatment is mainly prepared from the following components by weight: 20-50 parts of Radix Sophorae Flavescentis, 20-50 parts of Herba Taraxaci, 20-50 parts of Flos Chrysanthemi Indici, and 20-50 parts of Herba Cum Radice Violae Yedoensitis, 20-50 parts of Rhizoma Smilacis Glabrae, 30-60 parts of Radix Astragali Seu Hedysari, 10-35 parts of Kochia scoparia (L.) Schrad, 10-45 parts of Carthamus tinctorius L., 15-45 parts of Cortex Radicis Dictamni Dasycarpi, 5-15 parts of Herba Ephedrae, 5-25 parts of Angelica sinensis, 5-25 parts of Rhizoma Ligustici Chuangxiong, 10-30 parts of Radix Rehmanniae, 5-15 parts of Ramulus cinnamomi, 10-30 parts of Cynanchum otophyllum Schneid, 5-15 parts of Semen Sinapis Albae, 5-20 parts of Arisaema heterophyllum Blume, 5-20 parts of Typhonium blumei Nicolson & Sivadasan, and 10-40 parts of Radix Glycyrrhizae.
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公开(公告)号：US20240148705A1
公开(公告)日：2024-05-09
申请号：US18407337
申请日：2024-01-08
发明人： Gary Kompothecras , Michael Mullan , Daniel Paris
IPC分类号： A61K31/4375 , A61K9/00 , A61K9/48 , A61K31/4355 , A61K36/21 , A61K36/54 , A61K36/9066 , A61K47/22 , A61K47/36 , A61K47/46
CPC分类号： A61K31/4375 , A61K9/0014 , A61K9/48 , A61K31/4355 , A61K36/21 , A61K36/54 , A61K36/9066 , A61K47/22 , A61K47/36 , A61K47/46
摘要： A composition comprising a therapeutically effective amount of at least one alkaloid combined with one or more non-alkaloid components, wherein the composition is configured to be administered to a subject.
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公开(公告)号：US11865107B2
公开(公告)日：2024-01-09
申请号：US17009960
申请日：2020-09-02
发明人： Gary Kompothecras , Michael Mullan , Daniel Paris
IPC分类号： A61K31/4375 , A61K9/48 , A61K47/46 , A61K47/36 , A61K31/4355 , A61K9/00 , A61K36/9066 , A61K36/21 , A61K36/54 , A61K47/22
CPC分类号： A61K31/4375 , A61K9/0014 , A61K9/48 , A61K31/4355 , A61K36/21 , A61K36/54 , A61K36/9066 , A61K47/22 , A61K47/36 , A61K47/46
摘要： A composition comprising a therapeutically effective amount of at least one alkaloid combined with one or more non-alkaloid components, wherein the composition is configured to be administered to a subject.
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公开(公告)号：US20230354862A1
公开(公告)日：2023-11-09
申请号：US17927892
申请日：2022-01-26
发明人： Dae-sik HAM
IPC分类号： A23L33/105 , A61K36/21 , A61K36/23 , A61K36/73 , A61K36/81 , A61K36/31 , A61P3/10 , A23L2/02
CPC分类号： A23L33/105 , A61K36/21 , A61K36/23 , A61K36/73 , A61K36/81 , A61K36/31 , A61P3/10 , A23L2/02 , A61K2236/31 , A61K2236/19
摘要： The present invention relates to an anti-diabetic composition comprising a fermented product obtained by low-temperature aging a mixture of beets, carrots and apples. More specifically, an aged product, obtained by low-temperature aging of a mixture obtained by extracting and blending juices of beets, carrots and apples in a weight ratio of 1.5-3.5:1.5-2.5:4-7, has excellent blood sugar-reducing effects, such as concentration-dependent suppression of α-glucosidase and α-amylase activity, blood sugar reduction, reduction of fructosamime, insulin, HOMA-IR and HOMA-β content in the blood, and reduction of the area of β cells in Langerhans islands in pancreatic tissue, and thus can be useful as an anti-diabetic composition.
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公开(公告)号：US11771713B2
公开(公告)日：2023-10-03
申请号：US17313982
申请日：2021-05-06
IPC分类号： A61K31/70 , A01N43/04 , A61K31/706 , A61K36/185 , A23L5/43 , A23L33/105 , A61K31/7056 , A61K36/21 , A61K9/00
CPC分类号： A61K31/706 , A23L5/43 , A23L33/105 , A61K9/0053 , A61K31/7056 , A61K36/185 , A61K36/21 , A23V2002/00 , A23V2002/00 , A23V2250/21 , A23V2200/322
摘要： Contemplated compositions and methods employ betalains for treatment of various conditions, and especially osteoarthritis, sinusitis, contact dermatitis, acne, an allergic condition, reduced mental alertness, reduced physical strength, reduced physical endurance, and/or impaired mood.
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公开(公告)号：US11759477B2
公开(公告)日：2023-09-19
申请号：US17690611
申请日：2022-03-09
申请人： Heartbeet Ltd.
发明人： Jon Lundberg , Eddie Weitzberg
IPC分类号： A61K33/00 , A61K9/00 , A61K31/375 , A61K36/185 , A61K36/21 , A61K45/06 , A23L2/52 , A23L33/135 , A23L33/16 , A23L33/105 , A23L2/02 , A61K33/30 , A61K33/14 , A61K31/05 , A61K31/198 , A61P9/12 , A61K9/08 , C01D9/00
CPC分类号： A61K33/00 , A23L2/02 , A23L2/52 , A23L33/105 , A23L33/135 , A23L33/16 , A61K9/0056 , A61K9/0095 , A61K9/08 , A61K31/05 , A61K31/198 , A61K31/375 , A61K33/14 , A61K33/30 , A61K36/185 , A61K36/21 , A61K45/06 , A61P9/12 , A23V2002/00 , C01D9/00
摘要： Inorganic anions nitrate and nitrite influence metabolic rate and glucose homeostasis. Infusion of nitrite iv caused an acute drop in resting energy expenditure (oxygen consumption) and nitrate, when given perorally, caused a reduction in oxygen consumption during exercise and a depression of the increase in blood glucose observed after an oral glucose tolerance test. The doses of nitrate and nitrite did not cause any detectable change in methemoglobin levels of blood. Also, nitrate and nitrite did not alter lactate levels in blood. This discovery provides useful treatments to regulate the energy expenditure and glucose homeostasis of a mammal by administration of inorganic nitrite and/or nitrate.
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公开(公告)号：US20230285448A1
公开(公告)日：2023-09-14
申请号：US18199322
申请日：2023-05-18
申请人： Heartbeet Ltd.
发明人： Jon Lundberg , Eddie Weitzberg
IPC分类号： A61K33/00 , A61K31/375 , A61K36/21 , A23L33/105 , A61K45/06 , A23L33/135 , A23L2/52 , A61K9/00 , A61K36/185 , A23L33/16 , A23L2/02 , A61K33/30 , A61K33/14 , A61K31/05 , A61K31/198 , A61P9/12 , A61K9/08
CPC分类号： A61K33/00 , A61K31/375 , A61K36/21 , A23L33/105 , A61K45/06 , A23L33/135 , A23L2/52 , A61K9/0056 , A61K36/185 , A23L33/16 , A61K9/0095 , A23L2/02 , A61K33/30 , A61K33/14 , A61K31/05 , A61K31/198 , A61P9/12 , A61K9/08 , A23V2002/00 , C01D9/00
摘要： Inorganic anions nitrate and nitrite influence metabolic rate and glucose homeostasis. Infusion of nitrite iv caused an acute drop in resting energy expenditure (oxygen consumption) and nitrate, when given perorally, caused a reduction in oxygen consumption during exercise and a depression of the increase in blood glucose observed after an oral glucose tolerance test. The doses of nitrate and nitrite did not cause any detectable change in methemoglobin levels of blood. Also, nitrate and nitrite did not alter lactate levels in blood. This discovery provides useful treatments to regulate the energy expenditure and glucose homeostasis of a mammal by administration of inorganic nitrite and/or nitrate.
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