-
1.发明授权Purified and isolated heparan sulfate 3-O-sulfotransferase isoform 5 nucleic acids and polypeptides and therapeutic and screening methods using same 有权纯化和分离的硫酸乙酰肝素3-O-磺基转移酶同工型5核酸和多肽以及使用其的治疗和筛选方法公开(公告)号：US07531338B2
公开(公告)日：2009-05-12
申请号：US10520341
申请日：2003-07-07
申请人： Jian Liu , Guoqing Xia , Jinghua Chen , Michael B. Duncan , Deepak Shukla , Vaibhav Tiwari , Anders Malmstrom
发明人： Jian Liu , Guoqing Xia , Jinghua Chen , Michael B. Duncan , Deepak Shukla , Vaibhav Tiwari , Anders Malmstrom
CPC分类号： C12N9/13 , A01K2217/05 , A61K38/00 , A61K2039/505 , C12N2799/026 , C12N2799/028
摘要： 3-OST-5 proteins, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to 3-OST-5 homologs, and methods of producing the same, are also disclosed. 3OST-5 gene products have biological activity in specific heparan sulfate 3-O-sulfotransferase reactions. These reactions provide unique modified heparan sulfate. Thus, therapeutic methods involving this activity are also disclosed.
摘要翻译： 3-OST-5蛋白和编码它们的核酸分子。 还公开了重组宿主细胞，重组核酸和重组蛋白，以及各自产生的方法。 还公开了对3-OST-5同系物的分离和纯化的抗体及其制备方法。 3OST-5基因产物在特异性硫酸乙酰肝素3-O-磺基转移酶反应中具有生物活性。 这些反应提供了独特的改性硫酸乙酰肝素。 因此，还公开了涉及该活性的治疗方法。
-
2.发明申请Purified and isolated heparan sulfate 3-o-sulfotransferase isoform 5 nucleic acids and polypeptides and therapeutic and screening methods using same 有权纯化和分离的硫酸乙酰肝素3-o-磺基转移酶同工型5核酸和多肽以及使用其的治疗和筛选方法公开(公告)号：US20060165673A1
公开(公告)日：2006-07-27
申请号：US10520341
申请日：2003-07-07
申请人： Jian Liu , Guoqing Xia , Jinghua Chen , Michael Duncan , Deepark Shuka , Vaibhav Tiwari , Anders Malmstrom
发明人： Jian Liu , Guoqing Xia , Jinghua Chen , Michael Duncan , Deepark Shuka , Vaibhav Tiwari , Anders Malmstrom
CPC分类号： C12N9/13 , A01K2217/05 , A61K38/00 , A61K2039/505 , C12N2799/026 , C12N2799/028
摘要： 3-OST-5 proteins, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to 3-OST-5 homologs, and methods of producing the same, are also disclosed. 3OST-5 gene products have biological activity in specific heparan sulfate 3-O-sulfotransferase reactions. These reactions provide unique modified heparan sulfate. Thus, therapeutic methods involving this activity are also disclosed.
摘要翻译： 3-OST-5蛋白和编码它们的核酸分子。 还公开了重组宿主细胞，重组核酸和重组蛋白，以及各自产生的方法。 还公开了对3-OST-5同系物的分离和纯化的抗体及其制备方法。 3OST-5基因产物在特异性硫酸乙酰肝素3-O-磺基转移酶反应中具有生物活性。 这些反应提供了独特的改性硫酸乙酰肝素。 因此，还公开了涉及该活性的治疗方法。
-
3.发明申请公开(公告)号：US20050075314A1
公开(公告)日：2005-04-07
申请号：US10500284
申请日：2003-01-02
IPC分类号： A61K38/11 , A61K31/726 , A61K31/727 , A61K31/737 , A61P7/02 , A61P15/04 , A61P15/06 , C08B37/00 , C08B37/08 , C08B37/10 , A61K31/557
CPC分类号： A61K31/726 , A61K31/727
摘要： The invention refers to the use of sulfated glycosaminoglycans having an anticoagulant activity of 100 BP units/mg or less for the manufacture of a pharmaceutical preparation for prophylactic priming or curative treatment of the cervix and the myometrium for establishing effective labor in women.
摘要翻译： 本发明涉及使用抗凝血活性为100BP单位/ mg以下的硫酸化糖胺聚糖用于制造预防性引发或治疗子宫颈和子宫肌层用于在女性中有效劳动的药物制剂。
-
4.发明申请USE OF SULFATED GLYCOSAMINOGLYCANS FOR ESTABLISHING EFFECTIVE LABOR IN WOMEN 有权用于在妇女中建立有效劳动者的硫酸化谷氨酰胺酶的使用公开(公告)号：US20080269165A1
公开(公告)日：2008-10-30
申请号：US12168683
申请日：2008-07-07
IPC分类号： A61K31/727 , A61K31/726 , A61P15/04
CPC分类号： A61K31/726 , A61K31/727
摘要： The invention refers to the use of sulfated glycosamino-glycans having an anticoagulant activity of 100 BP units/mg or less for the manufacture of a pharmaceutical preparation for prophylactic priming or curative treatment of the cervix and the myometrium for establishing effective labor in women.
摘要翻译： 本发明涉及使用抗凝血活性为100BP单位/毫克以下的硫酸化糖胺基聚糖来制造预防性引发或治疗子宫颈和子宫肌层用于在妇女中有效劳动的药物制剂。
-
-
-
搜索结果
4 条记录 (耗时 0.03 秒)
