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    COMPOSITIONS AND METHODS FOR TISSUE REPAIR
    1.
    发明申请
    COMPOSITIONS AND METHODS FOR TISSUE REPAIR 审中-公开
    组织修复的组合物和方法

    公开(公告)号：US20090012629A1

    公开(公告)日：2009-01-08

    申请号：US12101553

    申请日：2008-04-11

    申请人： Jian Q. Yao ,  Ben Walthall ,  Jizong Gao ,  Victor Zaporojan

    发明人： Jian Q. Yao ,  Ben Walthall ,  Jizong Gao ,  Victor Zaporojan

    IPC分类号： A61F2/02

    CPC分类号： A61F2/30756 ,  A61F2/3094 ,  A61F2/3859 ,  A61F2002/2817 ,  A61F2002/30764 ,  A61F2002/30957 ,  A61F2002/30971 ,  A61F2002/4635 ,  A61F2310/00365 ,  A61L27/3604 ,  A61L27/38 ,  A61L27/3817 ,  A61L27/54 ,  A61L2300/25 ,  A61L2300/414 ,  A61L2300/64

    摘要： Implants for repairing tissue defects, such as cartilage tissue defects, and methods of their preparation and use are disclosed. A mold of a tissue defect is prepared by pressing upon the defect a substrate having shape memory, such as aluminum foil. The mold, which has contours substantially conforming to those of the defect, is removed from the defect, and tissue particles are added to the mold ex vivo. A biological carrier such as biocompatible glue is also added to the mold. The combination of tissue particles and the biological carrier thereby form an implant, which retains its shape after separation from the mold. The implant can be transferred to the tissue defect, with contours of the mold matching corresponding contours of the defect.

    摘要翻译： 公开了用于修复诸如软骨组织缺陷的组织缺陷的植入物及其制备和使用方法。 通过将缺陷压在诸如铝箔的形状记忆衬底上来制备组织缺陷的模具。 将具有基本上符合缺陷的轮廓的模具从缺陷中去除，并将组织颗粒离体加入到模具中。 生物相容性胶水等生物载体也加入到模具中。 因此，组织颗粒和生物载体的组合形成植入物，其在与模具分离后保持其形状。 植入物可以转移到组织缺损，模具的轮廓匹配缺陷的对应轮廓。

    APPARATUS FOR FORMING AN IMPLANT
    3.
    发明申请
    APPARATUS FOR FORMING AN IMPLANT 有权
    用于形成植入物的装置

    公开(公告)号：US20120107384A1

    公开(公告)日：2012-05-03

    申请号：US13327265

    申请日：2011-12-15

    申请人： Jian Q. Yao ,  Ben Walthall ,  Jizong Gao ,  Victor Zaporojan

    发明人： Jian Q. Yao ,  Ben Walthall ,  Jizong Gao ,  Victor Zaporojan

    IPC分类号： A61F2/02 ,  A61K35/32

    CPC分类号： A61F2/30756 ,  A61F2/3094 ,  A61F2/3859 ,  A61F2002/2817 ,  A61F2002/30764 ,  A61F2002/30957 ,  A61F2002/30971 ,  A61F2002/4635 ,  A61F2310/00365 ,  A61L27/3604 ,  A61L27/38 ,  A61L27/3817 ,  A61L27/54 ,  A61L2300/25 ,  A61L2300/414 ,  A61L2300/64

    摘要： Implants for repairing tissue defects, such as cartilage tissue defects, and methods of their preparation and use are disclosed. A mold of a tissue defect is prepared by pressing upon the defect a substrate having shape memory, such as aluminum foil. The mold, which has contours substantially conforming to those of the defect, is removed from the defect, and tissue particles are added to the mold ex vivo. A biological carrier such as biocompatible glue is also added to the mold. The combination of tissue particles and the biological carrier thereby form an implant, which retains its shape after separation from the mold. The implant can be transferred to the tissue defect, with contours of the mold matching corresponding contours of the defect.

    摘要翻译： 公开了用于修复诸如软骨组织缺陷的组织缺陷的植入物及其制备和使用方法。 通过将缺陷压在诸如铝箔的形状记忆衬底上来制备组织缺陷的模具。 将具有基本上符合缺陷的轮廓的模具从缺陷中去除，并将组织颗粒离体加入到模具中。 生物相容性胶水等生物载体也加入到模具中。 因此，组织颗粒和生物载体的组合形成植入物，其在与模具分离后保持其形状。 植入物可以转移到组织缺损，模具的轮廓匹配缺陷的对应轮廓。

    Collagen matrix for soft tissue augmentation
    4.
    发明申请
    Collagen matrix for soft tissue augmentation 审中-公开
    用于软组织增生的胶原基质

    公开(公告)号：US20050142161A1

    公开(公告)日：2005-06-30

    申请号：US10748894

    申请日：2003-12-30

    申请人： Lynetta Freeman ,  Susan Roweton ,  Ben Walthall ,  Kien Nguyen

    发明人： Lynetta Freeman ,  Susan Roweton ,  Ben Walthall ,  Kien Nguyen

    IPC分类号： A61L27/00 ,  A61L27/48 ,  A61L27/56 ,  A61L27/58 ,  A61K45/00 ,  A61K31/737

    CPC分类号： A61L27/58 ,  A61L27/48 ,  A61L27/56 ,  C08L5/00 ,  C08L89/06

    摘要： The present invention includes methods and materials for soft tissue implant formed from biologically-compatible polymeric matrixes. The matrixes may have pores sized for in-growth of soft tissue. The material may be utilized with collagen or other matrix materials. This material may be used in a method of reforming soft tissues by implanting the material within soft body tissues to modify soft tissue defects such as wrinkles or biopsy tissue defects and to reshape soft tissue.

    摘要翻译： 本发明包括由生物相容的聚合物基质形成的软组织植入物的方法和材料。 基质可以具有用于软组织生长的孔。 该材料可以与胶原蛋白或其他基质材料一起使用。 该材料可用于通过将材料植入软体组织中来改变软组织以改善软组织缺陷如皱纹或活检组织缺陷并重塑软组织的方法。

    MEDICAL DEVICE AND METHOD FOR DELIVERING AN IMPLANT TO AN ANATOMICAL SITE
    5.
    发明申请
    MEDICAL DEVICE AND METHOD FOR DELIVERING AN IMPLANT TO AN ANATOMICAL SITE 审中-公开
    用于将植入物递送到解剖学位置的医疗装置和方法

    公开(公告)号：US20090054906A1

    公开(公告)日：2009-02-26

    申请号：US12196831

    申请日：2008-08-22

    申请人： Ben Walthall ,  Rodney E. Bristol ,  AnneMarie Gonin

    发明人： Ben Walthall ,  Rodney E. Bristol ,  AnneMarie Gonin

    IPC分类号： A61F11/00 ,  A61B17/58 ,  A61B17/00

    CPC分类号： A61B17/1635 ,  A61B17/3468 ,  A61F2/4601 ,  A61F2/4618 ,  A61F2/4644 ,  A61F2002/30601 ,  A61F2002/4627 ,  A61F2002/4662 ,  A61F2002/4681

    摘要： A medical device and method for providing an implant to an anatomical site are disclosed. The medical device generally comprises a sleeve having first and second ends, a cutting frame coupled to the second end, and a rod received in an inner bore of the sleeve. The cutting frame defines a guide configured to direct a cutting tool for reciprocal motion along a cutting plane. When the implant is positioned within the inner bore, the rod and sleeve are used to gauge a depth of the anatomical site and to advance a portion of the implant beyond the cutting plane. The implant may then be cut to an appropriate size to fit the anatomical site.

    摘要翻译： 公开了一种用于向解剖部位提供植入物的医疗装置和方法。 医疗装置通常包括具有第一和第二端的套筒，联接到第二端的切割框架和容纳在套筒的内孔中的杆。 切割框架限定了引导件，其构造成引导切割工具沿切割平面往复运动。 当植入物定位在内孔内时，杆和套筒用于测量解剖部位的深度并将植入物的一部分推进超过切割平面。 然后将植入物切割成合适的尺寸以适合解剖部位。