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    INTRAOCULAR LENSES FOR MANAGING GLARE, ADHESION, AND CELL MIGRATION
    1.
    发明申请
    INTRAOCULAR LENSES FOR MANAGING GLARE, ADHESION, AND CELL MIGRATION 有权

    公开(公告)号：US20080077239A1

    公开(公告)日：2008-03-27

    申请号：US11534200

    申请日：2006-09-21

    申请人： Leander Zickler ,  Rakhi Jain ,  Jim Deacon

    发明人： Leander Zickler ,  Rakhi Jain ,  Jim Deacon

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1613 ,  A61F2002/009 ,  A61F2002/1681 ,  A61F2002/1696 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2250/0053 ,  A61F2250/0096 ,  A61F2250/0098 ,  H04W52/146 ,  H04W52/367

    摘要： An intraocular lens for providing vision to a subject contains an optic, a support structure coupled to the optic. The intraocular lens also includes a textured surface and/or subsurface layer. The optic is disposed about an optical axis and comprises an anterior surface and an opposing posterior surface, the surfaces being configured to focus light when implanted within an eye having a capsular bag. The textured surface is disposed over a surface portion of the intraocular lens and includes a plurality of periodically-spaced protrusions, each protrusion having a smooth distal face and a sharp corner edge configured to engage a wall of the capsular bag and/or at least one cell disposed along the wall. The subsurface layer is configured to scatter an amount of light that is at least twice the amount of light scattered by portions of the material adjacent the subsurface layer or at least twice the amount of light scattered by another intraocular lens that does not have the subsurface layer, but which is otherwise substantially equivalent.

    Intraocular lenses for managing glare, adhesion, and cell migration
    2.
    发明授权
    Intraocular lenses for managing glare, adhesion, and cell migration 有权
    用于管理眩光，粘附和细胞迁移的人工晶状体

    公开(公告)号：US08568478B2

    公开(公告)日：2013-10-29

    申请号：US11534200

    申请日：2006-09-21

    申请人： Leander Zickler ,  Rakhi Jain ,  Jim Deacon

    发明人： Leander Zickler ,  Rakhi Jain ,  Jim Deacon

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1613 ,  A61F2002/009 ,  A61F2002/1681 ,  A61F2002/1696 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2250/0053 ,  A61F2250/0096 ,  A61F2250/0098 ,  H04W52/146 ,  H04W52/367

    摘要： An intraocular lens for providing vision to a subject contains an optic, a support structure coupled to the optic. The intraocular lens also includes a textured surface and/or subsurface layer. The optic is disposed about an optical axis and comprises an anterior surface and an opposing posterior surface, the surfaces being configured to focus light when implanted within an eye having a capsular bag. The textured surface is disposed over a surface portion of the intraocular lens and includes a plurality of periodically-spaced protrusions, each protrusion having a smooth distal face and a sharp corner edge configured to engage a wall of the capsular bag and/or at least one cell disposed along the wall. The subsurface layer is configured to scatter an amount of light that is at least twice the amount of light scattered by portions of the material adjacent the subsurface layer or at least twice the amount of light scattered by another intraocular lens that does not have the subsurface layer, but which is otherwise substantially equivalent.

    摘要翻译： 用于向受试者提供视力的眼内透镜包括光学部件，耦合到光学部件的支撑结构。 眼内透镜还包括纹理表面和/或表面下层。 光学元件围绕光轴布置并且包括前表面和相对的后表面，所述表面被配置为当植入在具有囊袋的眼睛内时聚焦光。 纹理表面设置在眼内透镜的表面部分上方并且包括多个周期性间隔开的突起，每个突出部具有光滑的远侧面和尖锐的角部边缘，该尖锐边缘被配置为接合囊袋的壁和/或至少一个 细胞沿着壁布置。 地下层被配置为散射一定量的光，该光量是与邻近地下层的材料的部分散射的光量的至少两倍，或至少是不具有地下层的另一个人工晶状体散射的光量的两倍 ，但其他情况基本相同。

    INTRAOCULAR LENSES FOR MANAGING GLARE, ADHESION, AND CELL MIGRATION
    3.
    发明申请
    INTRAOCULAR LENSES FOR MANAGING GLARE, ADHESION, AND CELL MIGRATION 审中-公开
    用于管理眼睛，粘连和细胞迁移的内窥镜

    公开(公告)号：US20080077238A1

    公开(公告)日：2008-03-27

    申请号：US11534199

    申请日：2006-09-21

    申请人： Jim Deacon ,  Rakhi Jain ,  Leander Zickler

    发明人： Jim Deacon ,  Rakhi Jain ,  Leander Zickler

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1613 ,  A61F2002/0086 ,  A61F2002/009 ,  A61F2002/1681 ,  A61F2002/1696 ,  A61F2002/1699 ,  A61F2220/0008

    摘要： An intraocular lens for providing vision to a subject contains an optic, a support structure coupled to the optic. The intraocular lens also includes a textured surface and/or subsurface layer. The optic is disposed about an optical axis and comprises an anterior surface and an opposing posterior surface, the surfaces being configured to focus light when implanted within an eye having a capsular bag. The textured surface is disposed over a surface portion of the intraocular lens and includes a plurality of periodically-spaced protrusions, each protrusion having a smooth distal face and a sharp corner edge configured to engage a wall of the capsular bag and/or at least one cell disposed along the wall. The subsurface layer is configured to scatter an amount of light that is at least twice the amount of light scattered by portions of the material adjacent the subsurface layer or at least twice the amount of light scattered by another intraocular lens that does not have the subsurface layer, but which is otherwise substantially equivalent.

    摘要翻译： 用于向受试者提供视力的眼内透镜包括光学部件，耦合到光学部件的支撑结构。 眼内透镜还包括纹理表面和/或表面下层。 光学元件围绕光轴布置并且包括前表面和相对的后表面，所述表面被配置为当植入在具有囊袋的眼睛内时聚焦光。 纹理表面设置在眼内透镜的表面部分上方并且包括多个周期性间隔开的突起，每个突出部具有光滑的远侧面和尖锐的角部边缘，该尖锐边缘被配置为接合囊袋的壁和/或至少一个 细胞沿着壁布置。 地下层被配置为散射一定量的光，该光量是与邻近地下层的材料的部分散射的光量的至少两倍，或至少是不具有地下层的另一个人工晶状体散射的光量的两倍 ，但其他情况基本相同。

    Mark for intraocular lenses
    5.
    发明授权
    Mark for intraocular lenses 有权
    标记为眼内透镜

    公开(公告)号：US08357196B2

    公开(公告)日：2013-01-22

    申请号：US12620765

    申请日：2009-11-18

    申请人： Rakhi Jain ,  Douglas S. Cali ,  Huawei Zhao ,  David A. Ruddocks

    发明人： Rakhi Jain ,  Douglas S. Cali ,  Huawei Zhao ,  David A. Ruddocks

    IPC分类号： A61F2/16

    CPC分类号： A61F2/16 ,  A61F2002/1681 ,  A61F2250/0097

    摘要： An intraocular lens for providing vision to an animal or human subject has anterior and posterior sides. The lens includes an optic body, one or more haptics, and one or more marks. Each mark has four or more features disposed along an imaginary line when viewed from the anterior side and/or the posterior side. The mark(s) may be used as an aid in angularly aligning the lens during use.

    摘要翻译： 用于向动物或人类受试者提供视力的眼内透镜具有前侧和后侧。 透镜包括光学主体，一个或多个触觉件以及一个或多个标记。 当从前侧和/或后侧观察时，每个标记具有沿着假想线布置的四个或更多个特征。 标记可以用作在使用期间角度对准镜片的辅助。

    Glaucoma shunts with flow management and improved surgical performance
    6.
    发明授权
    Glaucoma shunts with flow management and improved surgical performance 有权
    青光眼分流具有流量管理和改善的手术表现

    公开(公告)号：US08702639B2

    公开(公告)日：2014-04-22

    申请号：US12732030

    申请日：2010-03-25

    申请人： Marrie H. Van Der Mooren ,  Theophilus Bogaert ,  Rakhi Jain

    发明人： Marrie H. Van Der Mooren ,  Theophilus Bogaert ,  Rakhi Jain

    IPC分类号： A61M5/00

    CPC分类号： A61F9/00781

    摘要： A method of treating glaucoma in an eye by managing fluid flow past an implanted shunt having an elastomeric plate and a non-valved elastomeric drainage tube. The plate is positioned over a sclera of the eye with an outflow end of the elastomeric drainage tube open to an outer face of the plate. An inflow end of the drainage tube tunnels through the sclera to the anterior chamber of the eye. The plate may have regions of greater propensity for cell adhesion alternating with regions of lesser cell adhesion. For example, regions of texturing around the plate or drainage tube may be provided to control the size of a bleb that forms over the implant. The effective surface area of the plate may be balanced against a number of fenestrations. The drainage tube has a reduced profile and may be shaped with a non-circular external cross-section to reduce its height. A scleral groove may be used to further reduce the height of the drainage tube on the sclera. A flow restrictor for the early post operative period will immediately lower the intraocular pressure (IOP) and simultaneously prevent hypotony.

    摘要翻译： 通过管理流体流过具有弹性体板和非瓣膜弹性体引流管的植入分流器来治疗眼睛中的青光眼的方法。 该板位于眼睛的巩膜上方，弹性体排出管的流出端向板的外表面敞开。 引流管的入流端通过巩膜隧道进入眼睛的前房。 该板可以具有较高的细胞粘附倾向的区域与较小细胞粘附的区域交替。 例如，可以提供围绕板或引流管的纹理区域以控制在植入物上形成的泡沫的尺寸。 板的有效表面积可以与多个开窗平衡。 排水管具有减小的轮廓并且可以被成形为具有非圆形的外部横截面以减小其高度。 可以使用巩膜槽来进一步降低巩膜上引流管的高度。 用于术后早期的限流器将立即降低眼内压（IOP）并同时防止低血压。

    MARK FOR INTRAOCULAR LENSES
    8.
    发明申请
    MARK FOR INTRAOCULAR LENSES 有权
    标记用于镜片内窥镜

    公开(公告)号：US20110118836A1

    公开(公告)日：2011-05-19

    申请号：US12620765

    申请日：2009-11-18

    申请人： Rakhi Jain ,  Douglas Cali ,  Huawei Zhao

    发明人： Rakhi Jain ,  Douglas Cali ,  Huawei Zhao

    IPC分类号： A61F2/16

    CPC分类号： A61F2/16 ,  A61F2002/1681 ,  A61F2250/0097

    摘要： An intraocular lens for providing vision to an animal or human subject has anterior and posterior sides. The lens includes an optic body, one or more haptics, and one or more marks. Each mark has four or more features disposed along an imaginary line when viewed from the anterior side and/or the posterior side. The mark(s) may be used as an aid in angularly aligning the lens during use.

    摘要翻译： 用于向动物或人类受试者提供视力的眼内透镜具有前侧和后侧。 透镜包括光学主体，一个或多个触觉件以及一个或多个标记。 当从前侧和/或后侧观察时，每个标记具有沿着假想线布置的四个或更多个特征。 标记可以用作在使用期间角度对准镜片的辅助。

    METHODS FOR ENHANCING ACCOMMODATION OF A NATURAL LENS OF AN EYE
    10.
    发明申请
    METHODS FOR ENHANCING ACCOMMODATION OF A NATURAL LENS OF AN EYE 有权
    用于增强眼睛自然透镜容纳度的方法

    公开(公告)号：US20110077624A1

    公开(公告)日：2011-03-31

    申请号：US12570780

    申请日：2009-09-30

    申请人： Daniel G Brady ,  Rakhi Jain

    发明人： Daniel G Brady ,  Rakhi Jain

    IPC分类号： A61B18/18 ,  A61M35/00

    CPC分类号： A61F9/008 ,  A61F9/00736 ,  A61F2009/0087 ,  A61F2009/00889 ,  A61F2009/00895

    摘要： The accommodative properties of the natural lens of an eye, which tend to degrade with age, can be enhanced, restored, or otherwise improved using the in situ treatment techniques and methodologies provided here. One exemplary method of enhancing accommodative properties of the natural lens of an eye involves an initial step of specifying treatment areas of the natural lens. These treatment areas correspond to regions of the capsular bag or regions of the crystalline lens. The method continues by increasing stiffness of the treatment areas while all or portions of the natural lens remains in situ. This results in stiffened areas of the natural lens that enhance transfer of ciliary muscle forces to a center region of the crystalline lens.

    摘要翻译： 随着年龄的增长倾向于降解眼睛的天然晶状体的调节性能可以使用本文提供的原位治疗技术和方法进行增强，恢复或改善。 提高眼睛的天然晶状体的调节特性的一个示例性方法涉及指定天然晶状体的治疗区域的初始步骤。 这些处理区域对应于囊袋的区域或晶状体的区域。 该方法通过增加处理区域的刚度而继续，同时全部或部分天然晶状体保持原位。 这导致天然晶状体的加强区域增强了睫状肌力转移到晶状体的中心区域。