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1.发明授权Genes and gene expression products that are differentially regulated in prostate cancer 失效在前列腺癌中差异调控的基因和基因表达产物公开(公告)号：US06476207B1
公开(公告)日：2002-11-05
申请号：US09328475
申请日：1999-06-09
申请人： Jimmy Zhang , Jon H. Astle , Eddie Carroll, III , Wilson O. Endege , Donna M. Ford , John E. Monahan , Robert Schlegel , Kathleen E. Steinmann
发明人： Jimmy Zhang , Jon H. Astle , Eddie Carroll, III , Wilson O. Endege , Donna M. Ford , John E. Monahan , Robert Schlegel , Kathleen E. Steinmann
IPC分类号： C12Q168
CPC分类号： C07K14/47 , A61K38/00 , C12Q1/6886 , C12Q2600/112 , C12Q2600/136 , G01N33/57434 , G01N33/57488
摘要： This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic and therapeutic agents related to the genes and proteins, including probes, antisense constructs, and antibodies. The invention further relates to polynucleotides differentially expressed in prostate cancer.
摘要翻译： 本发明涉及新的人类基因，由基因表达的蛋白质以及蛋白质的变体。 本发明还涉及与基因和蛋白质相关的诊断和治疗剂，包括探针，反义构建体和抗体。 本发明还涉及在前列腺癌中差异表达的多核苷酸。
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公开(公告)号：US06262334B1
公开(公告)日：2001-07-17
申请号：US09385982
申请日：1999-08-30
申请人： Wilson O. Endege , Kathleen E. Steinmann , Jon H. Astle , Christopher C. Burgess , Eddie Carroll, III , Theodore J. Catino , Poornima Dwivedi , Donna M. Ford , Marcia E. Lewis , Gary A. Molino , John E. Monahan , Robert Schlegel
发明人： Wilson O. Endege , Kathleen E. Steinmann , Jon H. Astle , Christopher C. Burgess , Eddie Carroll, III , Theodore J. Catino , Poornima Dwivedi , Donna M. Ford , Marcia E. Lewis , Gary A. Molino , John E. Monahan , Robert Schlegel
IPC分类号： A01K6700
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136
摘要： This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic assays and therapeutic agents related to the genes and proteins, including probes, antisense constructs, and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly in colon cancer tissue.
摘要翻译： 本发明涉及新的人类基因，由基因表达的蛋白质以及蛋白质的变体。 本发明还涉及与基因和蛋白质相关的诊断测定和治疗剂，包括探针，反义构建体和抗体。 已经发现目标核酸在肿瘤细胞，特别是结肠癌组织中是差异调节的。
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公开(公告)号：US06262333B1
公开(公告)日：2001-07-17
申请号：US09328111
申请日：1999-06-08
申请人： Wilson O. Endege , Kathleen E. Steinmann , Jon H. Astle , Christopher C. Burgess , Steven E. Bushnell , Eddie Carroll, III , Theodore J. Catino , Adnan Derti , Donna M. Ford , Marcia E. Lewis , John E. Monahan , Robert Schlegel
发明人： Wilson O. Endege , Kathleen E. Steinmann , Jon H. Astle , Christopher C. Burgess , Steven E. Bushnell , Eddie Carroll, III , Theodore J. Catino , Adnan Derti , Donna M. Ford , Marcia E. Lewis , John E. Monahan , Robert Schlegel
IPC分类号： A01K6700
摘要： This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic assays and therapeutic agents related to the genes and proteins, including probes, antisense constructs. and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly colon cancer cell lines and/or tissue.
摘要翻译： 本发明涉及新的人类基因，由基因表达的蛋白质以及蛋白质的变体。 本发明还涉及与基因和蛋白质相关的诊断测定和治疗剂，包括探针，反义构建体。 和抗体。 已经发现目标核酸在肿瘤细胞，特别是结肠癌细胞系和/或组织中是差异调节的。
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4.发明授权Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer 失效用于鉴别，评估，预防和治疗乳腺癌的组合物，试剂盒和方法公开(公告)号：US07601505B2
公开(公告)日：2009-10-13
申请号：US10855588
申请日：2004-05-26
申请人： John E. Monahan , Sebastian Hoersch , Dustin L. Anderson , Wilson O. Endege , Donna Ford , Karen Glatt , Bella O. Gorbatcheva , Shubhangi Kamatkar , Yong Yao Xu , Manjula Gannavarapu , Xumei Zhao , Robert Schlegel , Maureen Mertens , Robert C. Bast, Jr. , Gabriel N. Hortobagyi , Lajos Pusztai
发明人： John E. Monahan , Sebastian Hoersch , Dustin L. Anderson , Wilson O. Endege , Donna Ford , Karen Glatt , Bella O. Gorbatcheva , Shubhangi Kamatkar , Yong Yao Xu , Manjula Gannavarapu , Xumei Zhao , Robert Schlegel , Maureen Mertens , Robert C. Bast, Jr. , Gabriel N. Hortobagyi , Lajos Pusztai
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , G01N33/57415
摘要： The invention relates to nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast cancers are provided.
摘要翻译： 本发明涉及与乳腺癌相关的核酸分子和蛋白质。 提供了用于检测，表征，预防和治疗人乳腺癌的组合物，试剂盒和方法。
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5.发明申请NUCLEIC ACID MOLECULES AND PROTEINS FOR THE IDENTIFICATION, ASSESSMENT, PREVENTION, AND THERAPY OF OVARIAN CANCER 审中-公开核酸分子和蛋白质鉴定，评估，预防和治疗OVARIAN CANCER公开(公告)号：US20100291068A1
公开(公告)日：2010-11-18
申请号：US12719554
申请日：2010-03-08
申请人： Wilson O. Endege , Donna Ford , Manjula Gannavarapu , Karen Glatt , Sebastian Hoersch , Shubhangi Kamatkar , John E. Monahan , Robert Schlegel , Yong Yao Xu , Xumei Zhao , Robert C. Bast, JR. , Gordon B. Mills , Karen Lu
发明人： Wilson O. Endege , Donna Ford , Manjula Gannavarapu , Karen Glatt , Sebastian Hoersch , Shubhangi Kamatkar , John E. Monahan , Robert Schlegel , Yong Yao Xu , Xumei Zhao , Robert C. Bast, JR. , Gordon B. Mills , Karen Lu
IPC分类号： A61K39/395 , C12Q1/02 , C12Q1/68 , G01N33/53 , C07H21/04 , C07K14/425 , C07K16/18 , A61P35/00
CPC分类号： C07K14/47 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5011 , G01N33/57449
摘要： The invention relates to newly discovered nucleic acid molecules and proteins associated with ovarian cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human ovarian cancers are provided.
摘要翻译： 本发明涉及新发现的与卵巢癌相关的核酸分子和蛋白质。 提供了用于检测，表征，预防和治疗人类卵巢癌的组合物，试剂盒和方法。
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6.发明授权Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer 失效用于鉴定，评估，预防和治疗卵巢癌的核酸分子和蛋白质公开(公告)号：US07799518B2
公开(公告)日：2010-09-21
申请号：US10961139
申请日：2004-10-07
申请人： Wilson O. Endege , Donna Ford , Manjula Gannavarapu , Karen Glatt , Sebastian Hoersch , Shubhangi Kamatkar , John E. Monahan , Robert Schlegel , Yong Yao Xu , Xumei Zhao
发明人： Wilson O. Endege , Donna Ford , Manjula Gannavarapu , Karen Glatt , Sebastian Hoersch , Shubhangi Kamatkar , John E. Monahan , Robert Schlegel , Yong Yao Xu , Xumei Zhao
IPC分类号： C12Q1/00 , C12Q1/68 , G01N33/53 , G01N33/574
CPC分类号： C07K14/47 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5011 , G01N33/57449
摘要： The invention relates to newly discovered nucleic acid molecules and proteins associated with ovarian cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human ovarian cancers are provided.
摘要翻译： 本发明涉及新发现的与卵巢癌相关的核酸分子和蛋白质。 提供了用于检测，表征，预防和治疗人类卵巢癌的组合物，试剂盒和方法。
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7.发明申请COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND THERAPY OF BREAST CANCER 审中-公开乳腺癌的鉴定，评估，预防和治疗的组合物，试剂盒和方法公开(公告)号：US20100075325A1
公开(公告)日：2010-03-25
申请号：US12557795
申请日：2009-09-11
申请人： John E. Monahan , Sebastian Hoersch , Dustin L. Anderson , Wilson O. Endege , Donna Ford , Karen Glatt , Bella O. Gorbatcheva , Shubhangi Kamatkar , Yong Yao Xu , Manjula Gannavarapu , Xumei Zhao , Robert Schlegel , Maureen Mertens Hattersley , Robert C. Bast, JR. , Gabriel N. Hortobagyi , Lajos Pusztai
发明人： John E. Monahan , Sebastian Hoersch , Dustin L. Anderson , Wilson O. Endege , Donna Ford , Karen Glatt , Bella O. Gorbatcheva , Shubhangi Kamatkar , Yong Yao Xu , Manjula Gannavarapu , Xumei Zhao , Robert Schlegel , Maureen Mertens Hattersley , Robert C. Bast, JR. , Gabriel N. Hortobagyi , Lajos Pusztai
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , G01N33/57415
摘要： The invention relates to nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast cancers are provided.
摘要翻译： 本发明涉及与乳腺癌相关的核酸分子和蛋白质。 提供了用于检测，表征，预防和治疗人乳腺癌的组合物，试剂盒和方法。
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