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公开(公告)号：US07954492B2
公开(公告)日：2011-06-07
申请号：US11270678
申请日：2005-11-09
CPC分类号： A61M15/0065 , A61M15/0003 , A61M2202/064
摘要： To improve administration of powdered pharmaceuticals, a pharmaceutical powder cartridge (1) for powder inhalers for holding a pharmaceutical depot for a large number of pharmaceutical powder doses is proposed, having at least one storage space (6) and an integrated metering device, said integrated metering device comprising at least one metering slide (9, 13, 14) which can be moved approximately transversely in a metering slide channel (12) at least from a filling position to an emptying position, approximately transversely with respect to the direction of flow of the pharmaceutical powder out from the at least one storage space (6), said metering slide channel (12) with the at least one metering slide (9, 13, 14) being sealed off from the environment at least in the filling position of the metering slide (9, 13, 14), and also further measures and a corresponding inhaler.
摘要翻译： 为了改善粉末药物的给药，提出了一种用于容纳大量药物粉末剂量的药物贮库的用于粉末吸入器的药物粉盒（1），其具有至少一个储存空间（6）和一体式计量装置 计量装置包括至少一个计量滑动件（9,13,14），其可以在计量滑动通道（12）中大致横向移动至少从填充位置到排空位置，大致横向于相对于流动方向的流动方向 所述药物粉末从所述至少一个存储空间（6）出来，所述计量滑动通道（12）与所述至少一个计量滑动件（9,13,14）至少在所述至少一个计量滑动件 计量滑块（9,13,14），以及进一步措施和相应的吸入器。
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公开(公告)号：US07258118B2
公开(公告)日：2007-08-21
申请号：US10348874
申请日：2003-01-22
CPC分类号： A61M15/0065 , A61M15/0003 , A61M2202/064
摘要： To improve administration of powdered pharmaceuticals, a pharmaceutical powder cartridge (1) for powder inhalers for holding a pharmaceutical depot for a large number of pharmaceutical powder doses is proposed, having at least one storage space (6) and an integrated metering device, said integrated metering device comprising at least one metering slide (9, 13, 14) which can be moved approximately transversely in a metering slide channel (12) at least from a filling position to an emptying position, approximately transversely with respect to the direction of flow of the pharmaceutical powder out from the at least one storage space (6), said metering slide channel (12) with the at least one metering slide (9, 13, 14) being sealed off from the environment at least in the filling position of the metering slide (9, 13, 14), and also further measures and a corresponding inhaler.
摘要翻译： 为了改善粉末药物的给药，提出了一种用于容纳大量药物粉末剂量的药物贮库的用于粉末吸入器的药物粉盒（1），其具有至少一个储存空间（6）和一体式计量装置 计量装置包括至少一个计量滑动件（9,13,14），其可以在计量滑动通道（12）中大致横向移动至少从填充位置到排空位置，大致横向于相对于流动方向的流动方向 所述药物粉末从所述至少一个存储空间（6）出来，所述计量滑动通道（12）与所述至少一个计量滑动件（9,13,14）至少在所述至少一个计量滑动件 计量滑块（9,13,14），以及进一步措施和相应的吸入器。
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公开(公告)号：US20060081246A1
公开(公告)日：2006-04-20
申请号：US11270678
申请日：2005-11-09
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0003 , A61M2202/064
摘要： To improve administration of powdered pharmaceuticals, a pharmaceutical powder cartridge (1) for powder inhalers for holding a pharmaceutical depot for a large number of pharmaceutical powder doses is proposed, having at least one storage space (6) and an integrated metering device, said integrated metering device comprising at least one metering slide (9, 13, 14) which can be moved approximately transversely in a metering slide channel (12) at least from a filling position to an emptying position, approximately transversely with respect to the direction of flow of the pharmaceutical powder out from the at least one storage space (6), said metering slide channel (12) with the at least one metering slide (9, 13, 14) being sealed off from the environment at least in the filling position of the metering slide (9, 13, 14), and also further measures and a corresponding inhaler.
摘要翻译： 为了改善粉末药物的给药，提出了一种用于容纳大量药物粉末剂量的药物贮库的用于粉末吸入器的药物粉盒（1），其具有至少一个储存空间（6）和一体式计量装置 计量装置包括至少一个计量滑动件（9,13,14），其可以在计量滑动通道（12）中大致横向移动至少从填充位置到排空位置，大致横向于相对于流动方向的流动方向 所述药物粉末从所述至少一个存储空间（6）出来，所述计量滑动通道（12）与所述至少一个计量滑动件（9,13,14）至少在所述至少一个计量滑动件 计量滑块（9,13,14），以及进一步措施和相应的吸入器。
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4.发明授权Storage system for powdered pharmaceuticals, and inhaler equipped with this system 有权粉末药品储存系统和配有该系统的吸入器公开(公告)号：US07234464B2
公开(公告)日：2007-06-26
申请号：US09739170
申请日：2000-12-18
申请人： Joachim Goede , Karl-Heinz Lange
发明人： Joachim Goede , Karl-Heinz Lange
IPC分类号： A61M15/00
CPC分类号： A61M15/0003 , A61M15/0066 , A61M2202/064
摘要： A cartridge for powdered pharmaceuticals. At least two storage spaces are provided which are separate from each other and which are each intended to hold a multiplicity of doses of a medically active substance. The storage spaces are individual cartridges which may be lockingly coupled together to form a single cartridge. Each individual cartridge has a metering cavity.
摘要翻译： 用于粉末药物的药筒。 提供至少两个彼此分离的储存空间，它们各自用于容纳多种剂量的医用活性物质。 存储空间是可以锁定地联接在一起以形成单个盒的各个盒。 每个单独的墨盒具有计量腔。
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5.发明授权Storage system for powdered pharmaceuticals and inhaler equipped with this system 有权配有该系统的粉末药物和吸入器的储存系统公开(公告)号：US08375940B2
公开(公告)日：2013-02-19
申请号：US11753681
申请日：2007-05-25
申请人： Joachim Goede , Karl-Heinz Lange
发明人： Joachim Goede , Karl-Heinz Lange
IPC分类号： A61M15/00
CPC分类号： A61M15/0003 , A61M15/0066 , A61M2202/064
摘要： In order to improve the administration of powdered pharmaceuticals, the invention proposes a storage system for powdered pharmaceuticals, in particular for use or integration in a powder inhaler, for receiving a multiplicity of doses of at least one medically active substance, with at least two storage spaces (4) which are separate from each other and are each intended to hold a multiplicity of doses of a medically active substance, and the invention also proposes an inhaler for powdered pharmaceuticals, the inhaler comprising such a pharmaceutical powder cartridge system (1) as an integral part or as an exchangeable part.
摘要翻译： 为了改进粉状药物的给药，本发明提出了一种用于粉末状药物的储存系统，特别是用于或整合在粉末吸入器中，用于接收多种剂量的至少一种医用活性物质，其中至少两个储存 空间（4）彼此分开并且各自用于容纳多种剂量的医疗活性物质，并且本发明还提出了一种用于粉末状药物的吸入器，该吸入器包括这样的药物粉末盒系统（1），如 组成部分或可交换部分。
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6.发明申请STORAGE SYSTEM FOR POWDERED PHARMACEUTICALS AND INHALER EQUIPPED WITH THIS SYTEM 有权粉末制药储存系统和装有本SYIS的吸入器公开(公告)号：US20070215152A1
公开(公告)日：2007-09-20
申请号：US11753681
申请日：2007-05-25
申请人： Joachim Goede , Karl-Heinz Lange
发明人： Joachim Goede , Karl-Heinz Lange
CPC分类号： A61M15/0003 , A61M15/0066 , A61M2202/064
摘要： In order to improve the administration of powdered pharmaceuticals, the invention proposes a storage system for powdered pharmaceuticals, in particular for use or integration in a powder inhaler, for receiving a multiplicity of doses of at least one medically active substance, with at least two storage spaces (4) which are separate from each other and are each intended to hold a multiplicity of doses of a medically active substance, and the invention also proposes an inhaler for powdered pharmaceuticals, the inhaler comprising such a pharmaceutical powder cartridge system (1) as an integral part or as an exchangeable part.
摘要翻译： 为了改进粉状药物的给药，本发明提出了一种用于粉末状药物的储存系统，特别是用于或整合在粉末吸入器中，用于接收多种剂量的至少一种医用活性物质，其中至少两个储存 空间（4）彼此分开并且各自用于容纳多种剂量的医疗活性物质，并且本发明还提出了一种用于粉末状药物的吸入器，该吸入器包括这样的药物粉末盒系统（1），如 组成部分或可交换部分。
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7.发明授权Inhaler for the administration of powdered pharmaceuticals, and a powder cartridge system for use with this inhaler 有权用于管理粉末药物的吸入器以及用于该吸入器的粉剂盒系统公开(公告)号：US08051851B2
公开(公告)日：2011-11-08
申请号：US11183182
申请日：2005-07-18
申请人： Martin Herder , Ingo Mett , Joachim Goede
发明人： Martin Herder , Ingo Mett , Joachim Goede
CPC分类号： A61M15/0065 , A61M15/007 , A61M15/0073 , A61M15/0081 , A61M2202/064
摘要： In order to improve the security and reliability of administration of powdered pharmaceuticals through dry powder inhalers, the invention proposes an inhaler (1) for powdered medicaments, comprising an activating device (4) for manual engagement by the patient for repeatedly metering a dose of medicament to be administered to the patient, and further comprising an advancing mechanism (25) for advancing a counter or indexing means (8) each time the activating device (4) has been engaged by the patient so that a dose of medicament has been released for administration to the patient, wherein the counter or indexing means (8) comprises an index (9), the index (9) being detectable by a detection means (10) of the inhaler, and the detection means (10) being coupled to a locking mechanism (12), the locking mechanism (12) blocking the activating device (4) and/or any transportation mechanism (5) of the inhaler (1) delayed by a predetermined number of metering cycles since detection of the index (9), and a cartridge (3).
摘要翻译： 为了提高通过干粉吸入器管理粉末药物的安全性和可靠性，本发明提出了一种用于粉末药物的吸入器（1），其包括用于由患者手动接合的激活装置（4），用于反复计量剂量的药物 并且还包括用于在每次所述致动装置（4）已经被所述患者接合时推进计数器或分度装置（8）的推进机构（25），使得已经释放了剂量的药物 其中所述计数器或索引装置（8）包括索引（9），所述索引（9）可由所述吸入器的检测装置（10）检测，并且所述检测装置（10）被耦合到 锁定机构（12），所述锁定机构（12）阻挡所述吸入器（1）和/或所述吸入器（1）的任何运输机构（5）的延迟预定数量的计量循环，从而检测到所述inde x（9）和盒（3）。
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8.发明申请Inhaler for the administration of powdered pharmaceuticals, and a powder cartridge system for use with this inhaler 有权用于管理粉末药物的吸入器以及用于该吸入器的粉剂盒系统公开(公告)号：US20060037612A1
公开(公告)日：2006-02-23
申请号：US11183182
申请日：2005-07-18
申请人： Martin Herder , Ingo Mett , Joachim Goede
发明人： Martin Herder , Ingo Mett , Joachim Goede
CPC分类号： A61M15/0065 , A61M15/007 , A61M15/0073 , A61M15/0081 , A61M2202/064
摘要： In order to improve the security and reliability of administration of powdered pharmaceuticals through dry powder inhalers, the invention proposes an inhaler (1) for powdered medicaments, comprising an activating device (4) for manual engagement by the patient for repeatedly metering a dose of medicament to be administered to the patient, and further comprising an advancing mechanism (25) for advancing a counter or indexing means (8) each time the activating device (4) has been engaged by the patient so that a dose of medicament has been released for administration to the patient, wherein the counter or indexing means (8) comprises an index (9), the index (9) being detectable by a detection means (10) of the inhaler, and the detection means (10) being coupled to a locking mechanism (12), the locking mechanism (12) blocking the activating device (4) and/or any transportation mechanism (5) of the inhaler (1) delayed by a predetermined number of metering cycles since detection of the index (9), and a cartridge (3).
摘要翻译： 为了提高通过干粉吸入器管理粉末药物的安全性和可靠性，本发明提出了一种用于粉末药物的吸入器（1），其包括用于由患者手动接合的激活装置（4），用于反复计量剂量的药物 并且还包括用于在每次所述致动装置（4）已经被所述患者接合时推进计数器或分度装置（8）的推进机构（25），使得已经释放了剂量的药物 其中所述计数器或索引装置（8）包括索引（9），所述索引（9）可由所述吸入器的检测装置（10）检测，并且所述检测装置（10）被耦合到 锁定机构（12），所述锁定机构（12）阻挡所述致动装置（4）和/或所述吸入器（1）的任何运送机构（5）延迟预定数量的计量循环 因为检测到索引（9）和盒（3）。
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9.发明授权Oral forms of administration containing solid flupirtine with controlled release of active substance 失效含有活性物质控制释放的固体氟吡汀的口服形式的给药公开(公告)号：US06667058B1
公开(公告)日：2003-12-23
申请号：US08212578
申请日：1994-03-17
IPC分类号： A61K908
CPC分类号： A61K31/44 , A61K9/2077 , A61K9/209 , A61K9/5078 , A61K9/5084
摘要： Pharmaceutical dosage units containing flupirtine or a pharmaceutically acceptable salt of flupirtine with controlled release of active substance using a delayed-action or controlled-release component. There are 0.001 to 20 parts delayed-action component for each part by weight flupirtine (calculated as the base) and the release rate of flupirtine is between 5 and 300 mg per hour. In some cases, the dosage units may also contain a rapidly releasing component of flupirtine or of one of its salts. The dosage units reduce the sedative effect of flupirtine.
摘要翻译： 含有氟吡汀或氟吡汀药学上可接受的盐的药物剂量单位，其使用延迟作用或控制释放组分控制释放活性物质。 对于每份重量的氟吡汀（以碱为基准计），有0.001-20份延迟作用组分，氟吡汀的释放速率为5至300mg /小时。 在一些情况下，剂量单位还可以含有氟吡汀或其一种盐的快速释放组分。 剂量单位降低氟吡汀的镇静作用。
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10.发明授权
公开(公告)号：US5840279A
公开(公告)日：1998-11-24
申请号：US667414
申请日：1996-06-21
CPC分类号： A61M15/00 , A61M11/002 , A61M15/0065 , A61M15/0068 , A61M15/0095 , A61M15/0096 , A61M2202/064
摘要： Pharmaceutical powder cartridge for powder inhalers for receiving a medicament depot for a large number of pharmaceutical powder doses, having an integrated metering device which comprises at least one metering cavity for receiving a predetermined quantity of a pharmaceutical powder, the integrated metering device being capable of being moved at least out of a filling position into an emptying position approximately transversely with respect to the flow direction of the pharmaceutical powder, and an inhaler for powdered medicaments, in which inhaler the medicament can be received by a patient by means of an air stream and which has a receptacle for such a pharmaceutical powder cartridge.
摘要翻译： 用于接收用于大量药物粉末剂量的药物贮库的粉末吸入器的药物粉末盒，其具有集成的计量装置，其包括用于接收预定量的药物粉末的至少一个计量腔，所述综合计量装置能够 至少从填充位置移动到相对于药物粉末的流动方向大致横向的排空位置，以及用于粉末状药物的吸入器，其中药物可以由患者通过气流接收，并且 其具有用于这种药物粉末盒的容器。
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