公开(公告)号：US20240358485A1

公开(公告)日：2024-10-31

申请号：US18649689

申请日：2024-04-29

申请人： The Trustees of Indiana University

发明人： Brian D. Overshiner ,  William Roy Thompson ,  Parker Evans ,  Perla Reyes Fernandez ,  Daniel Georgiev Simeonov

IPC分类号： A61D7/00 ,  A61M15/00

CPC分类号： A61D7/00 ,  A61M15/0066 ,  A61M2205/3306 ,  A61M2205/581 ,  A61M2205/8206

摘要： Animal drug delivery systems and methods. Such a system includes a carrier cartridge to carry and dispense a plurality of drug doses, a monitoring device, and a controller operatively coupled with the carrier cartridge and the monitoring device. The controller operates the carrier cartridge to dispense at least one of the drug doses to an animal subject at each of a plurality of preselected dispensing intervals. The controller is also configured to operate the monitoring device to record the animal subject ingesting the dispensed drug doses. The system may be configured to provide drug pellets to mice based on researcher needs, allow for mouse monitoring to confirm drug delivery, enable behavioral studies to be conducted using operant condition, and/or to fit into a specific lab research animal cage.

公开(公告)号：US12128175B2

公开(公告)日：2024-10-29

申请号：US16668026

申请日：2019-10-30

申请人： CannaKorp, Inc.

发明人： Michael Patrick Bourque

IPC分类号： A61M15/00 ,  A61M11/00 ,  A61M11/02 ,  A61M11/04 ,  G16H40/63 ,  A61L9/03

CPC分类号： A61M15/0023 ,  A61M11/003 ,  A61M11/02 ,  A61M11/042 ,  A61M15/0003 ,  A61M15/0005 ,  A61M15/0016 ,  A61M15/002 ,  A61M15/0028 ,  A61M15/0035 ,  A61M15/0043 ,  A61M15/0086 ,  A61M15/0098 ,  G16H40/63 ,  A61L9/03 ,  A61M15/0066 ,  A61M2205/276 ,  A61M2205/3306 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3553 ,  A61M2205/3584 ,  A61M2205/3653 ,  A61M2205/368 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/6018 ,  A61M2205/6072 ,  A61M2205/702 ,  A61M2205/8206 ,  A61M2205/8275 ,  A61M2205/8293 ,  A61M2209/045

摘要： The present disclosure relates to systems and methods for producing a consistent and effective herbal vapor. A sealed container pod may include a chamber wall defining an internal volume within which a pre-processed herbal composition (e.g., cannabis) is located. The container pod may include filters for the vapor produced from the herbal composition. The container pod may also include a support member for holding and evenly distributing the herbal composition within the internal volume during vaporization. A vaporizer may be configured to obtain information regarding the contents of the herbal composition. The vaporizer may expose the herbal composition to an automated series of timed temperature adjustments specifically tailored for producing a desirable herbal vapor. The herbal vapor may be collected into a bag and/or canister for subsequent consumption.

公开(公告)号：US20240172791A1

公开(公告)日：2024-05-30

申请号：US18552358

申请日：2022-02-21

申请人： DP Innovations Kft.

发明人： Tibor Ajpli ,  Tamas Kolb ,  Balazs Polacesk ,  David Uzoni

IPC分类号： A24F40/30 ,  A24F40/10 ,  A24F40/50 ,  A61M15/00 ,  A61M16/00

CPC分类号： A24F40/30 ,  A24F40/10 ,  A24F40/50 ,  A61M15/0003 ,  A61M15/0066 ,  A61M16/0003 ,  A61M2016/0024 ,  A61M2016/0027 ,  A61M2205/3334 ,  A61M2205/8206

摘要： The invention is an inhalation device for delivering an atomized mixture of liquids with a regulated mixing ratio, comprising



two reservoirs storing a liquid,
for each reservoir a piezoelectric actuator (10a, 10b) for atomizing the liquid, and a liquid transferring member being in contact with the liquid and the piezoelectric actuator (10a, 10b), and
a pressure sensor (16a, 16b) for detecting a user inhalation,
a regulating electric circuit comprising a controller (18) generating an output PWM signal having a duty cycle, and an output stage (20a, 20b) comprising

an inductor (12a, 12b) forming a resonant circuit with the piezoelectric actuator (10a, 10b), and
a switch (14a, 14b) for driving the output stage (20a, 20b) by the output PWM signal,


the mixing ratio of the atomized liquids is determined by the duty cycles of the output PWM signals.

公开(公告)号：US20240100270A1

公开(公告)日：2024-03-28

申请号：US18537449

申请日：2023-12-12

申请人： Maury D. COLE

发明人： Maury D. COLE

IPC分类号： A61M15/00 ,  A01K1/00 ,  A01K1/03 ,  A01K29/00 ,  A61M16/06 ,  A61M16/10 ,  A61M16/14

CPC分类号： A61M15/0086 ,  A01K1/0005 ,  A01K1/031 ,  A01K29/005 ,  A61M15/0066 ,  A61M16/0627 ,  A61M16/1075 ,  A61M16/14 ,  A61M15/0003 ,  A61M15/0021 ,  A61M16/022

摘要： A stand-alone chamber or multi-chamber inhalation system has at least two alternative vaporized test liquid supply systems for passive or self-administered delivery of vaporized test fluid and air to one or more test chambers, which can be passive or restraint chambers, based on operator selection of delivery on and off times in a passive mode or actuation of an actuator in the chamber by a test animal in a self-administered mode. In one case, a multiple inhalation chamber system has two or more separate test fluid delivery systems and provides options for selective passive uniform drug delivery to multiple chambers or selective delivery of two or more different drugs to different groups of chambers from different delivery systems so that two different drugs or different concentrations of delivered drugs can be tested simultaneously.

公开(公告)号：US20230372645A1

公开(公告)日：2023-11-23

申请号：US18029940

申请日：2021-10-04

申请人： APTAR FRANCE SAS

发明人： Fabien ADAM ,  Mickaël BAILLIE

IPC分类号： A61M15/00 ,  G01F11/36 ,  G01F15/00

CPC分类号： A61M15/0066 ,  A61M15/0021 ,  A61M15/002 ,  G01F11/36 ,  G01F15/005 ,  A61M2205/50

摘要： The invention concerns a device for dispensing a fluid product comprising a body (10), a mouthpiece (20), a reservoir (100) containing a fluid product and a propellant gas slidably mounted in said body, a valve (200) comprising a valve member (210) assembled on said reservoir, the outlet from said valve member being connected to said mouthpiece by a channel (15), and an electronic unit (400), wherein:



said valve is continuous, with an actuation position in which the reservoir is connected to the outlet from said valve member,
said body comprises a cover (30) which, in the closed position, urges said valve member into its actuation position,
said device comprises a metering system (300) controlled by said electronic unit, said metering system comprising a shutter (310) which is closed at rest and which, during actuation, is displaced into its open position for a predetermined time in order to dispense a dose of fluid product.

公开(公告)号：US20230337733A1

公开(公告)日：2023-10-26

申请号：US17907218

申请日：2020-07-02

申请人： CQENS Technologies Inc.

发明人： Alexander Chinhak Chong ,  William Bartkowski ,  David Crosby ,  David Wayne ,  Gerard Shudall

IPC分类号： A24F40/42 ,  A24F40/20 ,  A24F40/465 ,  A24F40/70 ,  A24F40/485 ,  A24F40/51 ,  A24F40/57 ,  A24F40/53 ,  H05B6/10 ,  A61M15/00 ,  A61M15/06

CPC分类号： A24F40/42 ,  A24F40/20 ,  A24F40/465 ,  A24F40/70 ,  A24F40/485 ,  A24F40/51 ,  A24F40/57 ,  A24F40/53 ,  H05B6/105 ,  A61M15/009 ,  A61M15/06 ,  A61M15/0066 ,  A61M2205/3344 ,  A61M2205/3372 ,  A61M2205/3306 ,  A61M2205/6063 ,  A61M2205/3653

摘要： A device for converting a consumable into an aerosol with high heat without burning the consumable by packaging the consumable around a susceptor for inductive heating so as to reduce the oxygen content within the consumable. The susceptor can be a flattened piece of steel wool. The encasement can be a coating applied to the consumable can be packaging inside an encasement through which the aerosol can pass. Efficiency of the to create a porous shell. The device can have a receiver with an airtight seal and an airflow controller to optimize the aerosolizing process. The device can also have a recognition system to detect a sign on the consumable-containing package an execute the appropriate administration protocol.

公开(公告)号：US11779716B2

公开(公告)日：2023-10-10

申请号：US16635657

申请日：2018-08-01

申请人： KINDEVA DRUG DELIVERY L.P.

发明人： Philip A. Jinks ,  Frans A. Audenaert

IPC分类号： A61M15/00 ,  B05D7/14 ,  B05D7/00 ,  C08G65/336 ,  C08G75/20

CPC分类号： A61M15/0066 ,  B05D7/14 ,  B05D7/52 ,  C08G65/336 ,  C08G75/20 ,  A61M2205/0238 ,  B05D2202/15 ,  B05D2202/25 ,  B05D2506/10 ,  B05D2518/00 ,  C08G2650/48

摘要： Methods of making components for a medicinal delivery device are described, in which a base composition comprising a polysulphone is applied to the surface of a component to create a base layer, a primer composition comprising a silane having two or more reactive silane groups separated by an organic linker group is applied to the base layer to create primed surface, and a coating composition comprising an at least partially fluorinated compound is applied to the primed surface. Corresponding coated components and a medicinal delivery device are disclosed.

公开(公告)号：US20230302238A1

公开(公告)日：2023-09-28

申请号：US18020750

申请日：2021-08-20

申请人： Norton (Waterford) Limited

发明人： Mark Milton-Edwards ,  Guilherme Safioti ,  Michael Reich

IPC分类号： A61M15/00

CPC分类号： A61M15/008 ,  A61M15/0066 ,  A61M15/0026 ,  A61M2202/064

摘要： Provided is a system for providing an output for warning of a respiratory disease exacerbation in a subject. The system comprises a first inhaler for delivering a rescue medicament to the subject. The system optionally includes a second inhaler for delivering a maintenance medicament to the subject during a routine inhalation. A sensor system is configured to measure a parameter relating to airflow during the rescue inhalation and/or during the routine inhalation, when the second inhaler is included in the system. The system further comprises a processing module configured to monitor a frequency of the determined rescue inhalations. The processing module also monitors the parameter as a function of time. The processing module is further configured to provide the output for warning of a respiratory disease exacerbation if the parameter as a function of time is indicative of the lung condition of the subject deteriorating over a first time period, and the frequency of the determined rescue inhalations is higher during a second time period than during the first time period, the second time period being subsequent to the first time period. Further provided is a method for providing an output for warning of a respiratory disease exacerbation in a subject.

公开(公告)号：US20190191773A1

公开(公告)日：2019-06-27

申请号：US16288824

申请日：2019-02-28

申请人： Logic Technology Development, LLC

发明人： Eli Alelov

IPC分类号： A24F47/00 ,  A61M15/00 ,  A61M11/00 ,  A61M11/04 ,  A61M15/06

CPC分类号： A24F47/008 ,  A61M11/005 ,  A61M11/042 ,  A61M15/0003 ,  A61M15/0065 ,  A61M15/0066 ,  A61M15/008 ,  A61M15/0083 ,  A61M15/0085 ,  A61M15/06 ,  A61M2016/0021 ,  A61M2016/0024 ,  A61M2205/3306 ,  A61M2205/3368 ,  A61M2205/3375 ,  A61M2205/502 ,  A61M2205/583 ,  A61M2205/8206

摘要： A smoke inhalation device may include a housing, a first cartridge comprising a first release device configured to release a first substance, a second cartridge comprising a second release device configured to release a second substance, and a controller configured to control the operation of the first release device and the second release device. The first release device and the second release device may be configured to be operated independently from one another, such that a combined vapor composition including the first substance and the second substance is configured to be varied.

公开(公告)号：US20180344954A1

公开(公告)日：2018-12-06

申请号：US16055269

申请日：2018-08-06

申请人： Syqe Medical Ltd.

发明人： Perry DAVIDSON ,  Aaron SCHORR ,  Asaf KROLL ,  Binyamin SCHWARTZ

IPC分类号： A61M15/00 ,  H05B1/02 ,  A61M11/04 ,  A24F47/00 ,  A61K9/00 ,  A61K31/05 ,  A61K31/352 ,  A61M16/20 ,  A61M16/14 ,  A61M15/06 ,  A61K36/81 ,  A61K36/185 ,  A61K31/465 ,  A61M11/02

CPC分类号： A61M15/002 ,  A24F47/008 ,  A61K9/007 ,  A61K9/0073 ,  A61K31/05 ,  A61K31/352 ,  A61K31/465 ,  A61K36/185 ,  A61K36/81 ,  A61M11/02 ,  A61M11/041 ,  A61M11/042 ,  A61M15/0001 ,  A61M15/0003 ,  A61M15/0013 ,  A61M15/0015 ,  A61M15/0021 ,  A61M15/0028 ,  A61M15/0045 ,  A61M15/005 ,  A61M15/0051 ,  A61M15/0065 ,  A61M15/0066 ,  A61M15/0091 ,  A61M15/06 ,  A61M16/14 ,  A61M16/20 ,  A61M2205/0216 ,  A61M2205/3303 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/36 ,  A61M2205/502 ,  A61M2205/52 ,  H05B1/025

摘要： A dose unit including at least one isolated bioactive agent applied on a carrier material in thermal contact with an electrically heating element configured to vaporize a pre-determined amount of the agent for pulmonary delivery thereof is provided herein, as well as devices for effecting vaporization and pulmonary delivery of the isolated agent, and methods for preparing the dose unit, controllably releasing the agent therefrom, methods for pulmonary delivery thereof and methods of treatment of medical conditions treatable by pulmonary delivery of the isolated bioactive agent.