公开(公告)号：US06800792B1

公开(公告)日：2004-10-05

申请号：US09786960

申请日：2001-03-12

申请人： John A. Howard ,  Elizabeth Hood ,  Joseph Jilka

发明人： John A. Howard ,  Elizabeth Hood ,  Joseph Jilka

IPC分类号： C12N1509

CPC分类号： C12N9/0061 ,  C12N15/8205 ,  C12N15/8257

摘要： Expression of laccase in plants at commercial levels of production is provided. The laccase gene is preferably operably linked with promoter sequences preferentially directing expression of laccase to the seed of the plant, and may additionally include sequences directing expression to the plant cell wall. Methods of improving the process of introducing DNA into plants via Agrobacterium are also provided.

摘要翻译： 提供漆酶在商业生产水平的植物中的表达。 漆酶基因优选与优先引导漆酶表达的植物的启动子序列可操作地连接，并且还可以包括将表达指导到植物细胞壁的序列。 还提供了通过农杆菌改进将DNA导入植物的过程的方法。

公开(公告)号：US20120121635A1

公开(公告)日：2012-05-17

申请号：US13315340

申请日：2011-12-09

申请人： Michael Horn ,  Stephen Streatfiled ,  Joseph Jilka

发明人： Michael Horn ,  Stephen Streatfiled ,  Joseph Jilka

IPC分类号： A61K39/21 ,  A61P31/14 ,  A61P31/18

CPC分类号： C07K14/005 ,  C12N15/8258 ,  C12N2740/16122

摘要： Plants are engineered to express HIV related surface protein genes. The plants can be used as a source of the protein for a variety of purposes. Plant tissue can be orally administered to animals to elicit an immune response or provide protection from viral infection. The protein can be extracted and delivered to animals. Plant produced proteins can also provide a less expensive and more readily available source of the protein as reagents or in other experimentation involving HIV and SIV proteins.

摘要翻译： 植物被设计用于表达HIV相关的表面蛋白基因。 植物可以用作各种目的的蛋白质来源。 植物组织可以口服给予动物以引发免疫应答或提供免受病毒感染的保护。 可以将蛋白质提取并递送至动物。 植物产生的蛋白质还可以提供较便宜且更容易获得的蛋白质来源作为试剂或在涉及HIV和SIV蛋白质的其它实验中。

公开(公告)号：US5530193A

公开(公告)日：1996-06-25

申请号：US229287

申请日：1994-04-18

申请人： John M. Clark, Jr. ,  Joseph Jilka ,  Lynn E. Murry ,  Liliana E. C. Scarafia

发明人： John M. Clark, Jr. ,  Joseph Jilka ,  Lynn E. Murry ,  Liliana E. C. Scarafia

IPC分类号： C07K14/08 ,  C12N15/82 ,  A01H5/00 ,  A01H5/10 ,  C12N15/40

CPC分类号： C07K14/005 ,  C12N15/8283 ,  C12N2770/00022 ,  C12N2770/34022

摘要： Plants are transformed with the coat protein gene of one of various strains of Maize Dwarf Mosaic Virus (MDHV), and are protected from serious disease when challenged with exposure to the virus. The nucleic acid and amino acid sequences of MDMV strains A, B, and KS1 are given, as well as the constructs and vectors used to produce the transformed plants.

摘要翻译： 用各种玉米矮化马赛克病毒（MDHV）菌株的外壳蛋白基因转化植物，并在暴露于病毒时受到保护，免受严重疾病的侵袭。 给出了MDMV菌株A，B和KS1的核酸和氨基酸序列，以及用于产生转化植物的构建体和载体。