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公开(公告)号：US20100268321A1
公开(公告)日：2010-10-21
申请号：US12065888
申请日：2006-09-05
IPC分类号： A61F2/82 , A61K31/337 , A61K31/366 , A61K31/155 , A61F2/00 , A61P21/00 , A61P7/02
CPC分类号： A61L31/16 , A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/065 , A61F2210/0004 , A61F2250/0068 , A61L27/16 , A61L27/54 , A61L31/048 , A61L2300/206 , A61L2300/416 , A61L2300/42 , A61L2300/63 , C08L27/18
摘要： A method of incorporating drugs into an implantable medical device. In one variation, water insoluble drugs are used to form crystals within the porous structure of the device. Upon implantation, the drug crystals dissolve slowly and release the drug into the surrounding tissue. In one example, a water insoluble drug is crystallized within the pores of an ePTFE vascular graft.
摘要翻译： 将药物并入植入式医疗装置的方法。 在一个实施方案中，使用水不溶性药物在装置的多孔结构内形成晶体。 植入后，药物晶体缓慢溶解并将药物释放到周围组织中。 在一个实例中，水不溶性药物在ePTFE血管移植物的孔内结晶。
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公开(公告)号：US08758293B2
公开(公告)日：2014-06-24
申请号：US13524797
申请日：2012-06-15
申请人： John D. McDermott , Alexander W. Tessmer , William R. Bratt , David G. Spilka , Leonard J. Decant
发明人： John D. McDermott , Alexander W. Tessmer , William R. Bratt , David G. Spilka , Leonard J. Decant
IPC分类号： A61M29/00
CPC分类号： A61F2/95 , A61F2/01 , A61F2/86 , A61F2002/011 , A61F2240/001 , A61F2250/0067 , A61F2250/0068
摘要： Apparatuses and methods for coating and/or loading a medical device with a therapeutic agent prior to or during the placement of the medical device within the patient's body. In one variation, the medical device is coated and/or loaded with a therapeutic agent while the device is positioned in a delivery apparatus. In another variation, the delivery apparatus comprises a reservoir for retaining a therapeutic agent. The user may release the therapeutic agent from the reservoir prior to or during the placement of the device to coat and/or load the device with the therapeutic agent.
摘要翻译： 用于在将医疗装置放置在患者体内之前或期间用治疗剂涂覆和/或装载医疗装置的装置和方法。 在一个变型中，在将装置定位在输送装置中时，医疗装置被涂覆和/或装载治疗剂。 在另一个实施例中，递送装置包括用于保持治疗剂的储存器。 使用者可以在装置放置之前或期间从储存器释放治疗剂，以用该治疗剂涂覆和/或加载该装置。
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公开(公告)号：US08709069B2
公开(公告)日：2014-04-29
申请号：US11408330
申请日：2006-04-21
IPC分类号： A61F2/06
CPC分类号： A61F2/06 , A61F2/07 , A61F2240/005 , A61F2250/0039 , Y10T83/75
摘要： A vascular graft with trim lines is described, the trim lines providing a guide for precision shaping of the cuff. The trim lines may be printed or otherwise disposed on a surface of the cuff or included on a template designed for disposition over the cuff. The trim lines may also be disposed on a side of a pocket into which the cuff is positioned for trimming. Also described is an apparatus and method for precise trimming of a vascular graft.
摘要翻译： 描述了具有修剪线的血管移植物，修剪线为袖带的精密成形提供了指导。 修剪线可以被印刷或以其他方式设置在袖带的表面上或包括在设计用于配置在袖带上的模板上。 修剪线也可以设置在口袋的一侧，袖口定位在其中以进行修整。 还描述了一种用于精细修剪血管移植物的装置和方法。
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公开(公告)号：US08574261B2
公开(公告)日：2013-11-05
申请号：US13170054
申请日：2011-06-27
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61B90/39 , A61F2002/016 , A61F2220/0016 , A61F2230/005 , A61F2230/0067 , A61F2230/008 , A61F2250/0037 , A61F2250/0039 , A61F2250/0067 , A61F2250/0098
摘要： A removable blood clot filter includes a number of locator members and anchor members disposed radially and extending angularly downward from a hub. The locator members include a number of linear portions having distinct axes configured to place a tip portion approximately parallel to the walls of a blood vessel when implanted and to apply sufficient force to the vessel walls to position the filter near the vessel centerline. The anchor members each include a hook configured to penetrate the vessel wall to prevent longitudinal movement due to blood flow. The hooks may have a cross section sized to allow for a larger radius of curvature under strain so that the filter can be removed without damaging the vessel wall.
摘要翻译： 可移除的血液凝块过滤器包括多个定位器构件和锚定构件，其径向设置并且从轮毂向下倾斜延伸。 定位器构件包括多个线性部分，其具有不同的轴线，其被配置为在植入时使尖端部分大致平行于血管的壁，并且向血管壁施加足够的力以将过滤器定位在血管中心线附近。 锚定构件各自包括构造成穿透血管壁以防止由于血流引起的纵向运动的钩。 钩可以具有尺寸适于在应变下允许更大的曲率半径的横截面，使得可以移除过滤器而不损坏容器壁。
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公开(公告)号：US07967838B2
公开(公告)日：2011-06-28
申请号：US11429975
申请日：2006-05-09
CPC分类号： A61F2/01 , A61B90/39 , A61F2002/016 , A61F2220/0016 , A61F2230/005 , A61F2230/0067 , A61F2230/008 , A61F2250/0037 , A61F2250/0039 , A61F2250/0067 , A61F2250/0098
摘要： A removable blood clot filter includes a number of locator members and anchor members disposed radially and extending angularly downward from a hub. The locator members include a number of linear portions having distinct axes configured to place a tip portion approximately parallel to the walls of a blood vessel when implanted and to apply sufficient force to the vessel walls to position the filter near the vessel centerline. The anchor members each include a hook configured to penetrate the vessel wall to prevent longitudinal movement due to blood flow. The hooks may have a cross section sized to allow for a larger radius of curvature under strain so that the filter can be removed without damaging the vessel wall.
摘要翻译： 可移除的血液凝块过滤器包括多个定位器构件和锚定构件，其径向设置并且从轮毂向下倾斜延伸。 定位器构件包括多个线性部分，其具有不同的轴线，其被配置为在植入时使尖端部分大致平行于血管的壁，并且向血管壁施加足够的力以将过滤器定位在血管中心线附近。 锚定构件各自包括构造成穿透血管壁以防止由于血流引起的纵向运动的钩。 钩可以具有尺寸适于在应变下允许更大的曲率半径的横截面，使得可以移除过滤器而不损坏容器壁。
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公开(公告)号：US20100016946A1
公开(公告)日：2010-01-21
申请号：US12441085
申请日：2007-09-13
申请人： John D. McDermott
发明人： John D. McDermott
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/075 , A61F2002/826 , A61F2210/0004 , A61F2240/001 , B05D1/02 , B05D3/007 , B05D7/22 , Y10T29/49778 , Y10T29/49838
摘要： A stent-graft, including a generally tubular vascular graft of biocompatible material, and a plurality of bio-resorbable discrete annular members spaced apart along a longitudinal axis of the vascular graft and attached thereto.
摘要翻译： 支架移植物，包括生物相容性材料的大体管状血管移植物，以及沿着血管移植物的纵向轴线间隔开并连接到其上的多个生物可再吸收的离散环形构件。
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公开(公告)号：US08206348B2
公开(公告)日：2012-06-26
申请号：US11994294
申请日：2006-07-07
申请人： John D. McDermott , Alexander W. Tessmer , William R. Bratt , David G. Spilka , Leonard J. Decant, Jr.
发明人： John D. McDermott , Alexander W. Tessmer , William R. Bratt , David G. Spilka , Leonard J. Decant, Jr.
IPC分类号： A61M25/00
CPC分类号： A61F2/95 , A61F2/01 , A61F2/86 , A61F2002/011 , A61F2240/001 , A61F2250/0067 , A61F2250/0068
摘要： Apparatuses and methods for coating and/or loading a medical device with a therapeutic agent prior to or during the placement of the medical device within the patient's body. In one variation, the medical device is coated and/or loaded with a therapeutic agent while the device is positioned in a delivery apparatus. In another variation, the delivery apparatus comprises a reservoir for retaining a therapeutic agent. The user may release the therapeutic agent from the reservoir prior to or during the placement of the device to coat and/or load the device with the therapeutic agent.
摘要翻译： 用于在将医疗装置放置在患者体内之前或期间用治疗剂涂覆和/或装载医疗装置的装置和方法。 在一个变型中，在将装置定位在输送装置中时，医疗装置被涂覆和/或装载治疗剂。 在另一个实施例中，递送装置包括用于保持治疗剂的储存器。 使用者可以在装置放置之前或期间从储存器释放治疗剂，以用该治疗剂涂覆和/或加载该装置。
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公开(公告)号：US20110257677A1
公开(公告)日：2011-10-20
申请号：US13170054
申请日：2011-06-27
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61B90/39 , A61F2002/016 , A61F2220/0016 , A61F2230/005 , A61F2230/0067 , A61F2230/008 , A61F2250/0037 , A61F2250/0039 , A61F2250/0067 , A61F2250/0098
摘要： A removable blood clot filter includes a number of locator members and anchor members disposed radially and extending angularly downward from a hub. The locator members include a number of linear portions having distinct axes configured to place a tip portion approximately parallel to the walls of a blood vessel when implanted and to apply sufficient force to the vessel walls to position the filter near the vessel centerline. The anchor members each include a hook configured to penetrate the vessel wall to prevent longitudinal movement due to blood flow. The hooks may have a cross section sized to allow for a larger radius of curvature under strain so that the filter can be removed without damaging the vessel wall.
摘要翻译： 可移除的血液凝块过滤器包括多个定位器构件和锚定构件，其径向设置并且从轮毂向下倾斜延伸。 定位器构件包括多个线性部分，其具有不同的轴线，其被配置为在植入时使尖端部分大致平行于血管的壁，并且向血管壁施加足够的力以将过滤器定位在血管中心线附近。 锚定构件各自包括构造成穿透血管壁以防止由于血流引起的纵向运动的钩。 钩可以具有尺寸适于在应变下允许更大的曲率半径的横截面，使得可以移除过滤器而不损坏容器壁。
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公开(公告)号：US08647379B2
公开(公告)日：2014-02-11
申请号：US12983653
申请日：2011-01-03
申请人： John D. McDermott , Khoi Q. Ta
发明人： John D. McDermott , Khoi Q. Ta
IPC分类号： A61F2/82
CPC分类号： A61F2/88 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2220/0016 , A61F2220/0058 , A61F2250/0031 , A61L31/148
摘要： A helical stent having bio-resorbable connecting members connecting sections of the stent. The connecting members provide various spring rates or spring constants to the stent, and permit a change in the flexibility of the stent subsequent to implantation while maintaining the unitary design of the stent.
摘要翻译： 具有连接支架部分的生物可再吸收连接构件的螺旋支架。 连接构件向支架提供各种弹簧刚度或弹簧常数，并且允许植入后支架的柔性变化，同时保持支架的整体设计。
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公开(公告)号：US20110098801A1
公开(公告)日：2011-04-28
申请号：US12983653
申请日：2011-01-03
申请人： John D. McDermott , Khoi O. Ta
发明人： John D. McDermott , Khoi O. Ta
IPC分类号： A61F2/82
CPC分类号： A61F2/88 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2220/0016 , A61F2220/0058 , A61F2250/0031 , A61L31/148
摘要： A helical stent having bio-resorbable connecting members connecting sections of the stent. The connecting members provide various spring rates or spring constants to the stent, and permit a change in the flexibility of the stent subsequent to implantation while maintaining the unitary design of the stent.
摘要翻译： 具有连接支架部分的生物可再吸收连接构件的螺旋支架。 连接构件向支架提供各种弹簧刚度或弹簧常数，并且允许植入后支架的柔性变化，同时保持支架的整体设计。
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