公开(公告)号：US20070161560A1

公开(公告)日：2007-07-12

申请号：US11549189

申请日：2006-10-13

申请人： John Davis ,  Martin Gunthorpe ,  Julie Egerton ,  Darren Smart

发明人： John Davis ,  Martin Gunthorpe ,  Julie Egerton ,  Darren Smart

IPC分类号： A61K48/00 ,  A61K38/17 ,  C12Q1/68 ,  G01N33/567

CPC分类号： A61K38/177 ,  G01N33/566 ,  G01N33/6872 ,  G01N2500/00

摘要： The use of VR4 polypeptides and polynucleotides in the design of protocols for the treatment of diseases of cartilage, such as hyaline-, fibro- and elastic-cartilage, or diseases of tissues where such cartilage is found including diseases or disorders affecting the larynx, auditory canal, intervertebral discs, ligaments, tendons and joint capsules, bone development including osteoporosis, diseases involving joint destruction and also pain linked to rheumatoid arthritis and osteoarthritis.

摘要翻译： 在设计用于治疗软骨疾病的方案中使用VR4多肽和多核苷酸，例如透明，纤维和弹性软骨，或发现这种软骨的组织疾病，包括影响喉部的疾病或障碍，听觉 运动，椎间盘，韧带，腱和关节囊，骨发育，包括骨质疏松症，涉及关节破坏的疾病，以及与类风湿性关节炎和骨关节炎相关的疼痛。