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公开(公告)号：US10188413B1
公开(公告)日：2019-01-29
申请号：US11804308
申请日：2007-05-16
申请人： John H. Morriss , Joshua Makower , Mei Pader , Julia D. Vrany , Eric Goldfarb , Randy S. Chan
发明人： John H. Morriss , Joshua Makower , Mei Pader , Julia D. Vrany , Eric Goldfarb , Randy S. Chan
摘要： Deflectable guide catheters and methods, including methods for using defectable guide catheters to perform transnasal procedures within the ear, nose, throat, paranasal sinuses or cranium. Some deflectable guide catheters of the present invention comprise a substantially rigid tube, a helical spring attached to and extending from the distal end of the substantially rigid tube, a tubular plastic inner jacket, an outer plastic jacket substantially covering at least the helical spring member. The spring member is deflectable to cause the distal portion of the guide catheter to deflect to a curved configuration. In embodiments for transnasal use the deflectable guide catheter may have a length of less than 25 cm.
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2.发明申请METHOD AND SYSTEM FOR TREATING TARGET TISSUE WITHIN THE EUSTACHIAN TUBE 审中-公开用于治疗目标组织的方法和系统在EUSTACHIAN TUBE公开(公告)号：US20100198191A1
公开(公告)日：2010-08-05
申请号：US12649078
申请日：2009-12-29
申请人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany
发明人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany
CPC分类号： A61M29/02 , A61B1/227 , A61B1/233 , A61B5/036 , A61B5/415 , A61B8/12 , A61B17/24 , A61B18/08 , A61B18/20 , A61F11/002 , A61F11/004 , A61M25/0041 , A61M25/0054 , A61M25/0068 , A61M25/007 , A61M25/008 , A61M25/0662 , A61M25/09 , A61M25/10 , A61M25/1002 , A61M31/002 , A61M2025/0037 , A61M2025/0039 , A61M2025/09008 , A61M2025/09183 , A61M2025/105 , A61M2025/1054 , A61M2025/1086 , A61N7/02
摘要： Methods and systems for accessing a Eustachian tube of a patient are disclosed. The system includes a guide configured for passing into a nasal passage of the patient to position a distal tip of the catheter at or near a Eustachian tube, the guide having a distal tip with a bend having an angle between 30 and 90 degrees; and a guidewire configured to pass through the guide into the Eustachian tube. A device for providing therapy to the Eustachian tube is passed through the guide.
摘要翻译： 公开了用于访问患者的咽鼓管的方法和系统。 该系统包括引导件，其构造成用于进入患者的鼻通道以将导管的远侧末端定位在咽鼓管处或附近，该导管具有具有在30度和90度之间的角度的弯曲部的远端; 以及引导线，其构造成穿过所述引导件进入咽鼓管。 用于向咽鼓管提供治疗的装置通过引导件。
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公开(公告)号：US20100076269A1
公开(公告)日：2010-03-25
申请号：US12562828
申请日：2009-09-18
申请人： Joshua Makower , John Y. Chang , William M. Facteau , Eric Goldfarb , Ketan P. Muni , Earl A. Bright, II , Greg Garfield , Greg Liu , Thomas Jenkins , John H. Morriss , Julia D. Vrany , Hung V. Ha , Ronda M. Heiser , Scott M. Smith
发明人： Joshua Makower , John Y. Chang , William M. Facteau , Eric Goldfarb , Ketan P. Muni , Earl A. Bright, II , Greg Garfield , Greg Liu , Thomas Jenkins , John H. Morriss , Julia D. Vrany , Hung V. Ha , Ronda M. Heiser , Scott M. Smith
摘要： Systems and methods for treating paranasal sinuses in a head of a patient include, for example, forming an opening through a canine fossa into a maxillary paranasal sinus and performing a procedure such as a balloon catheter dilation of the maxillary sinus ostium. In some embodiments, one or more procedures other than a balloon dilation procedure may be performed. In some embodiments, a combination of balloon dilation and one or more other procedures may be performed. Various approaches involve employing medical devices to accomplish alternative treatment modalities as well as taking alternative routes to the interventional site.
摘要翻译： 用于治疗患者头部鼻窦的系统和方法包括例如通过犬窝形成通向上颌鼻旁窦的开口，并执行诸如上颌窦口的气囊导管扩张的过程。 在一些实施例中，可以执行除球囊扩张程序之外的一个或多个程序。 在一些实施例中，可以执行球囊扩张和一个或多个其它程序的组合。 各种方法涉及采用医疗设备来完成替代治疗方式，以及采取替代途径到介入部位。
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公开(公告)号：US08435290B2
公开(公告)日：2013-05-07
申请号：US12730492
申请日：2010-03-24
申请人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany , Ketan P. Muni , William E. Bolger , Joseph Roberson
发明人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany , Ketan P. Muni , William E. Bolger , Joseph Roberson
IPC分类号： A61F2/18
CPC分类号： A61F11/002
摘要： Methods and devices for providing a gas pathway between the nasopharynx and the Eustachian tube are provided. One device may include a lumen with a valve. A portion of the valve may be tethered to adjacent muscle. Another portion of the valve may be tethered to adjacent cartilage. When the muscle contracts the valve may open through movement of the tethers, and provide a gas pathway between the nasopharynx and the Eustachian tube.
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5.发明申请System and Method For Treatment of Non-Ventilating Middle Ear by Providing a Gas Pathway Through the Nasopharynx 有权通过提供通过鼻咽的气道来治疗非通气中耳的系统和方法公开(公告)号：US20100305697A1
公开(公告)日：2010-12-02
申请号：US12730492
申请日：2010-03-24
申请人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany , Ketan P. Muni , William E. Bolger , Joseph Roberson
发明人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany , Ketan P. Muni , William E. Bolger , Joseph Roberson
CPC分类号： A61F11/002
摘要： Methods and devices for providing a gas pathway between the nasopharynx and the Eustachian tube are provided. One device may include a lumen with a valve. A portion of the valve may be tethered to adjacent muscle. Another portion of the valve may be tethered to adjacent cartilage. When the muscle contracts the valve may open through movement of the tethers, and provide a gas pathway between the nasopharynx and the Eustachian tube.
摘要翻译： 提供了用于在鼻咽和咽鼓管之间提供气体通路的方法和装置。 一个装置可以包括具有阀的内腔。 阀的一部分可以系在相邻的肌肉上。 阀的另一部分可以连接到相邻的软骨上。 当肌肉收缩时，阀可以通过系绳的移动而打开，并且在鼻咽和咽鼓管之间提供气体通路。
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6.发明申请Method and System for Accessing, Diagnosing and Treating Target Tissue Regions Within the Middle Ear and the Eustachian Tube 审中-公开方法和系统，用于访问，诊断和治疗中耳和咽鼓管内的目标组织区域公开(公告)号：US20090163890A1
公开(公告)日：2009-06-25
申请号：US12340226
申请日：2008-12-19
申请人： Anton Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany
发明人： Anton Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany
CPC分类号： A61B8/12 , A61B1/227 , A61B1/233 , A61B5/036 , A61B5/411 , A61B5/415 , A61B18/20 , A61F11/004 , A61M25/0026 , A61M25/0041 , A61M25/0068 , A61M25/007 , A61M25/008 , A61M25/09 , A61M25/10 , A61M31/002 , A61M2025/09008 , A61N7/02
摘要： Method and systems for accessing a Eustachian tube of a patient are disclosed. The system includes a guide configured for passing into a nasal passage of the patient to position a distal tip of the catheter at or near a Eustachian tube, the guide having distal tip with a bend having an angle between 30 and 90 degrees; and a guidewire configured to pass through the guide into the Eustachian tube.
摘要翻译： 公开了用于访问患者的咽鼓管的方法和系统。 该系统包括引导件，其构造成用于进入患者的鼻通道，以将导管的远侧末端定位在咽鼓管处或附近，该导管具有远侧尖端，弯曲部具有30度和90度之间的角度; 以及引导线，其构造成穿过所述引导件进入咽鼓管。
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公开(公告)号：US20100030113A1
公开(公告)日：2010-02-04
申请号：US12512420
申请日：2009-07-30
CPC分类号： A61B1/233 , A61B17/24 , A61B2017/22042 , A61B2017/22051 , A61B2017/320048 , A61M25/1002 , A61M29/00 , A61M2029/025
摘要： Devices and methods for locating sinus ostia and positioning a guide wire within the sinus ostia. The subject devices comprise a shaft having a distal end, a proximal end, a curved region located between the distal and proximal ends, and an interior channel, an extensible and retractable guide wire movably mounted within the interior channel and a probe tip joined to the guide wire. Certain devices further include expandable portions for engaging and treating body anatomy.
摘要翻译： 用于定位窦口的装置和方法，并将导丝定位在窦口内。 主体装置包括轴，其具有远端，近端，位于远端和近端之间的弯曲区域，以及内部通道，可移动地安装在内部通道内的可伸缩引导线，以及连接到 导丝。 某些装置还包括用于接合和处理身体解剖结构的可扩张部分。
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公开(公告)号：US20110160740A1
公开(公告)日：2011-06-30
申请号：US12974834
申请日：2010-12-21
申请人： Joshua Makower , John Y. Chang , Eric Goldfarb , Bernard H. Andreas , Thomas R. Jenkins , Nicholas Sherman , Ronda M. Heiser , Hung V. Ha , John H. Morriss
发明人： Joshua Makower , John Y. Chang , Eric Goldfarb , Bernard H. Andreas , Thomas R. Jenkins , Nicholas Sherman , Ronda M. Heiser , Hung V. Ha , John H. Morriss
CPC分类号： A61B17/24 , A61B17/320016 , A61B17/32056 , A61B2017/22038 , A61B2017/22079 , A61M25/0105 , A61M25/1011 , A61M29/02 , A61M31/00 , A61M2025/0186 , A61M2025/109
摘要： Sinusitis, tumors, infections, fractures and other disorders of the paranasal sinuses, are diagnosed and/or treated using minimally invasive approaches. Access devices may be used to facilitate insertion of working devices such catheters, balloon catheters, dilation catheters, tissue cutting or remodeling devices, suction or irrigation devices and biopsy devices.
摘要翻译： 鼻窦炎，肿瘤，感染，骨折和其他鼻旁窦病变，使用微创方法进行诊断和/或治疗。 可以使用进入装置来促进诸如导管，球囊导管，扩张导管，组织切割或重塑装置，抽吸或冲洗装置和活检装置的工作装置的插入。
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公开(公告)号：US08979888B2
公开(公告)日：2015-03-17
申请号：US12512420
申请日：2009-07-30
CPC分类号： A61B1/233 , A61B17/24 , A61B2017/22042 , A61B2017/22051 , A61B2017/320048 , A61M25/1002 , A61M29/00 , A61M2029/025
摘要： Devices and methods for locating sinus ostia and positioning a guide wire within the sinus ostia. The subject devices include a shaft having a distal end, a proximal end, a curved region located between the distal and proximal ends, and an interior channel, an extensible and retractable guide wire movably mounted within the interior channel and a probe tip joined to the guide wire. Certain devices further include expandable portions for engaging and treating body anatomy.
摘要翻译： 用于定位窦口的装置和方法，并将导丝定位在窦口内。 主体装置包括具有远端，近端，位于远端和近端之间的弯曲区域和内部通道的轴，可移动地安装在内部通道内的可伸缩引导线，以及连接到 导丝。 某些装置还包括用于接合和处理身体解剖结构的可扩张部分。
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10.发明授权System and method for the simultaneous bilateral integrated tympanic drug delivery and guided treatment of target tissues within the ears 有权系统和方法同时进行双侧一体化鼓膜药物输送和引导治疗耳内目标组织公开(公告)号：US08849394B2
公开(公告)日：2014-09-30
申请号：US13587806
申请日：2012-08-16
申请人： Anton G. Clifford , Greg Liu , John H. Morriss , Joshua Makower , William M. Facteau , Eric Goldfarb , John Y. Chang
发明人： Anton G. Clifford , Greg Liu , John H. Morriss , Joshua Makower , William M. Facteau , Eric Goldfarb , John Y. Chang
CPC分类号： A61M31/00 , A61B5/0077 , A61B2017/00787 , A61F11/002 , A61F2230/0039 , A61F2230/0052 , A61F2250/0039 , A61M2210/0662 , A61N1/30 , A61N1/306
摘要： Systems and methods for treating a patient having a head with a first ear and a second ear function by mounting a support system to the head of the patient so that the support system is aligned with a target tissue of the first ear; applying a therapeutic agent to the first car by energizing an iontophoresis electrode supported by the support system; and actuating a device while the device is supported by the support system so that the device therapeutically remodels the target tissue of the first ear.
摘要翻译： 用于通过将支撑系统安装到患者的头部来治疗具有第一耳朵和第二耳朵功能的头部的患者的系统和方法，使得所述支撑系统与所述第一耳朵的目标组织对准; 通过激励由所述支撑系统支撑的离子电渗电极向所述第一轿厢施加治疗剂; 以及当所述装置由所述支撑系统支撑时启动装置，使得所述装置治疗性地改造所述第一耳朵的目标组织。
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