REAL TIME SELF-ADJUSTING CALIBRATION ALGORITHM
    1.
    发明申请
    REAL TIME SELF-ADJUSTING CALIBRATION ALGORITHM 审中-公开
    实时自调整校准算法

    公开(公告)号:US20090005666A1

    公开(公告)日:2009-01-01

    申请号:US12179536

    申请日:2008-07-24

    IPC分类号: A61B5/00

    摘要: A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and corresponding glucose monitor data to regress the obtained glucose monitor data. And, calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter, and the at least two reference glucose values are obtained from blood tests. In additional embodiments, calculation of the calibration characteristics includes linear regression and, in particular embodiments, least squares linear regression. Alternatively, calculation of the calibration characteristics includes non-linear regression. Data integrity may be verified and the data may be filtered.

    摘要翻译: 校准葡萄糖监测数据的方法包括以预定间隔在一段时间内收集葡萄糖监测数据。 它还包括从参考源获得至少两个参考葡萄糖值,所述参考源在时间上对应于以预定间隔获得的葡萄糖监测数据。 还包括使用参考葡萄糖值和相应的葡萄糖监测数据计算校准特性以回收所获得的葡萄糖监测数据。 并且包括使用校准特性来校准所获得的葡萄糖监测数据。 在优选实施例中,参考源是血糖仪,并且从血液测试获得至少两个参考葡萄糖值。 在另外的实施例中,校准特性的计算包括线性回归,并且在特定实施例中包括最小二乘线性回归。 或者,校准特性的计算包括非线性回归。 可以验证数据完整性,并且可以对数据进行过滤。

    Real time self-adjusting calibration algorithm
    2.
    发明授权
    Real time self-adjusting calibration algorithm 有权
    实时自调整校准算法

    公开(公告)号:US09204840B2

    公开(公告)日:2015-12-08

    申请号:US12179536

    申请日:2008-07-24

    摘要: A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and corresponding glucose monitor data to regress the obtained glucose monitor data. And, calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter, and the at least two reference glucose values are obtained from blood tests. In additional embodiments, calculation of the calibration characteristics includes linear regression and, in particular embodiments, least squares linear regression. Alternatively, calculation of the calibration characteristics includes non-linear regression. Data integrity may be verified and the data may be filtered.

    摘要翻译: 校准葡萄糖监测数据的方法包括以预定间隔在一段时间内收集葡萄糖监测数据。 它还包括从参考源获得至少两个参考葡萄糖值,所述参考源在时间上对应于以预定间隔获得的葡萄糖监测数据。 还包括使用参考葡萄糖值和相应的葡萄糖监测数据计算校准特性以回收所获得的葡萄糖监测数据。 并且包括使用校准特性来校准所获得的葡萄糖监测数据。 在优选实施例中,参考源是血糖仪,并且从血液测试获得至少两个参考葡萄糖值。 在另外的实施例中,校准特性的计算包括线性回归,并且在特定实施例中包括最小二乘线性回归。 或者,校准特性的计算包括非线性回归。 可以验证数据完整性,并且可以对数据进行过滤。

    Real time self-adjusting calibration algorithm
    3.
    发明授权
    Real time self-adjusting calibration algorithm 有权
    实时自调整校准算法

    公开(公告)号:US07890295B2

    公开(公告)日:2011-02-15

    申请号:US10750978

    申请日:2003-12-31

    IPC分类号: G06F11/30

    摘要: A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and corresponding glucose monitor data to regress the obtained glucose monitor data. And, calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter, and the at least two reference glucose values are obtained from blood tests. In additional embodiments, calculation of the calibration characteristics includes linear regression and, in particular embodiments, least squares linear regression. Alternatively, calculation of the calibration characteristics includes non-linear regression. Data integrity may be verified and the data may be filtered.

    摘要翻译: 校准葡萄糖监测数据的方法包括以预定间隔在一段时间内收集葡萄糖监测数据。 它还包括从参考源获得至少两个参考葡萄糖值,所述参考源在时间上对应于以预定间隔获得的葡萄糖监测数据。 还包括使用参考葡萄糖值和相应的葡萄糖监测数据计算校准特性以回收所获得的葡萄糖监测数据。 并且包括使用校准特性来校准所获得的葡萄糖监测数据。 在优选实施例中,参考源是血糖仪,并且从血液测试获得至少两个参考葡萄糖值。 在另外的实施例中,校准特性的计算包括线性回归,并且在特定实施例中包括最小二乘线性回归。 或者,校准特性的计算包括非线性回归。 可以验证数据完整性,并且可以对数据进行过滤。

    Closed loop system for controlling insulin infusion
    6.
    发明授权
    Closed loop system for controlling insulin infusion 有权
    用于控制胰岛素输注的闭环系​​统

    公开(公告)号:US06558351B1

    公开(公告)日:2003-05-06

    申请号:US09586175

    申请日:2000-06-01

    IPC分类号: A61M3700

    摘要: A closed loop infusion system controls the rate that fluid is infused into the body of a user. The closed loop infusion system includes a sensor system, a controller, and a delivery system. The sensor system includes a sensor for monitoring a condition of the user. The sensor produces a sensor signal, which is representative of the condition of the user. The sensor signal is used to generate a controller input. The controller uses the controller input to generate commands to operate the delivery system. The delivery system infuses a liquid into the user at a rate dictated by the commands from the controller. Preferably, the sensor system monitors the glucose concentration in the body of the user, and the liquid infused by the delivery system into the body of the user includes insulin. The sensor system uses the sensor signal to generate a message that is sent to the delivery system. The message includes the information used to generate the controller input. The sensor may be a subcutaneous sensor in contact with interstitial fluid. Also, two or more sensors may be used by the sensor system.

    摘要翻译: 闭环输注系统控制流体注入使用者身体的速度。 闭环输注系统包括传感器系统,控制器和输送系统。 传感器系统包括用于监测用户状况的传感器。 传感器产生一个传感器信号,代表用户的状态。 传感器信号用于生成控制器输入。 控制器使用控制器输入来生成操作传送系统的命令。 输送系统以由控制器的命令指示的速率将液体注入用户。 优选地,传感器系统监测用户体内的葡萄糖浓度,并且由输送系统输入到使用者体内的液体包括胰岛素。 传感器系统使用传感器信号来产生发送到传送系统的消息。 该消息包括用于生成控制器输入的信息。 传感器可以是与间质液接触的皮下传感器。 此外,传感器系统可以使用两个或更多个传感器。

    Glucose monitor calibration methods
    7.
    发明授权
    Glucose monitor calibration methods 有权
    葡萄糖监测仪校准方法

    公开(公告)号:US06424847B1

    公开(公告)日:2002-07-23

    申请号:US09511580

    申请日:2000-02-23

    IPC分类号: A61B500

    CPC分类号: A61B5/14532 A61M2005/1726

    摘要: A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and the corresponding glucose monitor data to regress the obtained glucose monitor data. And calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter, and the at least two reference glucose values are obtained from blood tests. In additional embodiments, the calculation of the calibration characteristics is obtained using linear regression and in particular embodiments, least squares linear regression. Alternatively, the calculation of the calibration characteristics is obtained using non-linear regression.

    摘要翻译: 校准葡萄糖监测数据的方法包括以预定间隔在一段时间内收集葡萄糖监测数据。 它还包括从参考源获得至少两个参考葡萄糖值,所述参考源在时间上对应于以预定间隔获得的葡萄糖监测数据。 还包括使用参考葡萄糖值和相应的葡萄糖监测数据计算校准特性以回归所获得的葡萄糖监测数据。 并且包括使用校准特性来校准所获得的葡萄糖监测数据。 在优选实施例中,参考源是血糖仪,并且从血液测试获得至少两个参考葡萄糖值。 在另外的实施例中,使用线性回归和特定实施例,最小二乘线性回归来获得校准特性的计算。 或者,使用非线性回归获得校准特性的计算。