公开(公告)号：US20050043570A1

公开(公告)日：2005-02-24

申请号：US10676682

申请日：2003-10-01

申请人： John Knifton ,  Talmadge James ,  Paul Weider ,  Joseph Powell ,  Edward Nielsen ,  Glenn Komplin

发明人： John Knifton ,  Talmadge James ,  Paul Weider ,  Joseph Powell ,  Edward Nielsen ,  Glenn Komplin

IPC分类号： C07C29/14 ,  C07C29/141 ,  C07C45/58 ,  C07C29/74 ,  C07C31/18

CPC分类号： C07C45/58 ,  C07C29/141 ,  C07C31/205

摘要： The present invention is an improvement upon the process for the production of 1,3-propanediol wherein an aqueous solution of 3-hydroxy propanal is formed, catalyst, if any, used in said formation is removed from the solution, sodium hydroxide is added to the solution to neutralize any acid therein such that the pH is at least about 5, the neutralized aqueous solution is subjected to hydrogenation to produce a crude 1,3-propanediol mixture which is distilled to produce 1,3-propanediol, water, and reactive heavy components. The improvement on this process comprises replacing the sodium hydroxide with a hydroxide selected from the group consisting of ammonium hydroxide, alkali metal hydroxides other than sodium hydroxide, and alkaline earth metal hydroxides to reduce the viscosity of the reactive heavy components.

摘要翻译： 本发明是对生产1,3-丙二醇的方法的改进，其中形成3-羟基丙醛的水溶液，从该溶液中除去所述地层中使用的催化剂（如果有的话），将氢氧化钠加入 中和其中的任何酸使其pH至少约为5的溶液，中和的水溶液进行氢化以产生粗制的1,3-丙二醇混合物，其被蒸馏以产生1,3-丙二醇，水和反应性 重组件。 该方法的改进包括用选自氢氧化铵，氢氧化钠以外的碱金属氢氧化物和碱土金属氢氧化物的氢氧化物代替氢氧化钠，以降低反应性重组分的粘度。

公开(公告)号：US20050038332A1

公开(公告)日：2005-02-17

申请号：US10860114

申请日：2004-06-03

申请人： Frank Saidara ,  John Mastrototaro ,  Charles Tolle ,  John Mueller ,  Jeff Sanders ,  Edward Nielsen

发明人： Frank Saidara ,  John Mastrototaro ,  Charles Tolle ,  John Mueller ,  Jeff Sanders ,  Edward Nielsen

IPC分类号： A61B5/00 ,  G01N33/487 ,  G06F19/00

CPC分类号： A61B5/0002 ,  A61B5/14532 ,  A61B5/1468 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/746 ,  A61B2560/0223 ,  A61B2560/0252 ,  A61B2560/045 ,  G01N33/48792 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3456 ,  G16H15/00 ,  G16H40/63

摘要： Apparatuses and methods for medical monitoring physiological characteristic values such as blood glucose levels for the treatment of diabetes, are presented. The apparatuses and methods provide for preventing any negative consequence in the operation of a monitor and/or infusion device as a result of disorientation that may occur from waking from slumber with a low blood glucose level. In addition, a graphical display is disclosed incorporating a variety of enhancements which readily conveys to the user historical as well as real time information regarding the measured characteristic value.

摘要翻译： 提出了用于医学监测生理特征值（例如用于治疗糖尿病的血糖水平）的装置和方法。 这些装置和方法提供了防止由于从具有低血糖水平的睡眠中醒来可能发生的定向障碍导致监视器和/或输注装置的操作中的任何负面后果。 此外，公开了一种图形显示，其包括易于传达给用户历史的各种增强以及关于测量的特征值的实时信息。