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    Lead system for use with an atrial defibrillator and method
    1.
    发明授权
    Lead system for use with an atrial defibrillator and method 失效
    用于心房除颤器的铅系统和方法

    公开(公告)号：US5350404A

    公开(公告)日：1994-09-27

    申请号：US130308

    申请日：1993-10-01

    申请人： John M. Adams ,  Clifton A. Alferness ,  Paul E. Kreyenhagen

    发明人： John M. Adams ,  Clifton A. Alferness ,  Paul E. Kreyenhagen

    IPC分类号： A61N1/05 ,  A61N1/372 ,  A61N1/39

    CPC分类号： A61N1/3918 ,  A61N1/056 ,  A61N1/0563 ,  A61N1/3956 ,  A61N1/3962 ,  A61N1/395 ,  A61N1/3987 ,  A61N2001/0585

    摘要： An implantable atrial defibrillator provides a pulse of defibrillating electrical energy to the atria of the heart in synchronism with sensed R waves in response to non-coincident sensing of an R wave at first and second areas of the heart. The defibrillating pulse is provided after a predetermined number of consecutive R waves are non-coincidently sensed to assure reliable synchronization. The atrial defibrillator is also operational in a marker mode wherein a number of synchronization marker pulses are delivered to the heart for detection on an externally generated electrocardiogram. The atrial fibrillation detector of the defibrillator is normally disabled and is activated when the sensed ventricular activity indicates a probability of atrial fibrillation to conserve a depletable power source. A plurality of lead systems are also described for use with the atrial defibrillator which reduce the quantity of electrical energy required to defibrillate the heart and ensure that the delivered atrial defibrillating electrical energy is substantially confined to the atria of the heart.

    摘要翻译： 可植入心房除颤器响应于在心脏的第一和第二区域处的R波的不一致的感测，与感测到的R波同步地向心脏的心房提供除颤电脉冲。 在不一致地感测到预定数量的连续R波之后提供除颤脉冲，以确保可靠的同步。 心房除颤器还可以在标记模式中操作，其中多个同步标记脉冲被传送到心脏以便在外部产生的心电图上进行检测。 除颤器的心房颤动检测器通常被禁用，并且当感测到的心室活动指示心房颤动的概率以节省可消耗的电源时被激活。 还描述了与心房除颤器一起使用的多个引导系统，其减少了除颤心脏所需的电能的量，并确保输送的心房除颤电能基本上限于心脏的心房。

    Disposable infusion device with automatic unlocking mechanism
    5.
    发明授权
    Disposable infusion device with automatic unlocking mechanism 有权
    具有自动解锁机构的一次性输液装置

    公开(公告)号：US08162923B2

    公开(公告)日：2012-04-24

    申请号：US11516812

    申请日：2006-09-06

    申请人： John M. Adams ,  Clifton A. Alferness ,  Daniel Hawkins

    发明人： John M. Adams ,  Clifton A. Alferness ,  Daniel Hawkins

    IPC分类号： A61K9/22

    CPC分类号： A61M5/152 ,  A61M5/14248

    摘要： A wearable infusion device delivers a liquid medicant to a patient. The infusion device comprises a base that contacts a patient's skin and a reservoir arranged to be filled with a liquid medicant to be delivered beneath a patient's skin. The reservoir has an outlet through which the medicant flows. The infusion device further comprises a flexible conduit communicating with the outlet of the reservoir, a pump that causes the medicant to flow down the conduit, an actuator that performs a function related to the operation of the device, and an enable mechanism that enables the actuator in response to the filling of the reservoir with the liquid medicant.

    摘要翻译： 可戴式输液装置将液体药剂递送给患者。 输液装置包括接触患者皮肤的基部和布置成填充有待在患者皮肤下方递送的液体药物的储存器。 储存器具有药物流过的出口。 输液装置还包括与储存器的出口连通的柔性导管，使得药剂沿着管道流下的泵，执行与装置的操作有关的功能的致动器，以及启动机构，其使致动器 响应于用液体药物填充储存器。

    Tissue fixation assembly having prepositioned fasteners and method
    8.
    发明申请
    Tissue fixation assembly having prepositioned fasteners and method 有权
    具有预定位紧固件和方法的组织固定组件

    公开(公告)号：US20100023028A1

    公开(公告)日：2010-01-28

    申请号：US12460247

    申请日：2009-07-15

    申请人： Steve G. Baker ,  Brett J. Carter ,  Stefan J. M. Kraemer ,  Clifton A. Alferness ,  John M. Adams ,  Raymond Michael Wolniewicz, III

    发明人： Steve G. Baker ,  Brett J. Carter ,  Stefan J. M. Kraemer ,  Clifton A. Alferness ,  John M. Adams ,  Raymond Michael Wolniewicz, III

    IPC分类号： A61B17/08

    CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/064 ,  A61B17/068 ,  A61B17/1114 ,  A61B2017/00827 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0419

    摘要： A tissue fastener assembly delivers a fastener for deployment. The assembly includes a fastener including a first member, a second member, the first and second members having first and second ends, and a flexible connecting member fixed to each of the first and second members intermediate the first and second ends and extending between the first and second members. The first member has a longitudinal axis and a through channel along the axis. The assembly further includes a deployment wire slidingly received within the through channel of the first member that pierces into the tissue and guides the first member through the tissue, a guide structure defining a lumen that receives the fastener and deployment wire and guides the deployment wire and fastener to the tissue, and a fastener configuration structure that orientates the second member in a predetermined position relative to the first member within the lumen for dependable deployment.

    摘要翻译： 组织紧固件组件递送用于展开的紧固件。 所述组件包括紧固件，所述紧固件包括第一构件，第二构件，所述第一和第二构件具有第一和第二端;以及柔性连接构件，其固定到所述第一和第二构件中的每一个，所述第一和第二构件在所述第一和第二端之间延伸， 和第二名成员。 第一构件具有沿轴线的纵向轴线和贯通通道。 组件还包括滑动地容纳在第一构件的穿过通道内的展开线，其穿透组织并引导第一构件穿过组织;限定内腔的引导结构，其接纳紧固件和展开线并引导展开线，并且 紧固件到组织，以及紧固件配置结构，其将第二构件相对于管腔内的第一构件定位在预定位置以进行可靠的展开。

    Atrial fibrillation detector
    9.
    发明授权
    Atrial fibrillation detector 失效
    心房颤动检测器

    公开(公告)号：US5464431A

    公开(公告)日：1995-11-07

    申请号：US410829

    申请日：1995-03-27

    申请人： John M. Adams ,  Clifton A. Alferness

    发明人： John M. Adams ,  Clifton A. Alferness

    IPC分类号： A61N1/05 ,  A61N1/39

    CPC分类号： A61N1/056 ,  A61N1/0563 ,  A61N1/3918 ,  A61N1/3956 ,  A61N1/3962 ,  A61N1/395 ,  A61N1/3987 ,  A61N2001/0585

    摘要： An atrial defibrillator implantable beneath the skin of a patient includes an intervention sequencer for performing an intervention sequence. The intervention sequencer includes an atrial fibrillation detector for determining if atrial fibrillation is present in a patient's heart and a cardiovertor for applying cardioverting electrical energy to the atria of the patient's heart if the atrial fibrillation detector determines that atrial fibrillation is present. A sequence initiating stage includes a receiver for receiving a sequence command generated from external to the patient. The sequence initiating stage causes the intervention sequencer to perform the intervention sequence upon receipt of a sequence command.

    摘要翻译： 植入患者皮肤下方的房颤除颤器包括用于执行干预顺序的干预序列发生器。 干预测序仪包括心房颤动检测器，用于确定心房颤动是否存在于患者的心脏中;以及心律转换器，如果心房颤动检测器确定存在心房颤动，则将心脏转复电能施加到患者心脏的心房。 序列发起阶段包括用于接收从患者外部产生的序列命令的接收器。 序列发起阶段使得干预序列器在接收到序列命令时执行干预序列。