Heat sterilization of glucocorticosteroids
    5.
    发明授权
    Heat sterilization of glucocorticosteroids 有权
    糖皮质激素加热灭菌

    公开(公告)号:US08791096B2

    公开(公告)日:2014-07-29

    申请号:US10594861

    申请日:2005-05-17

    IPC分类号: A61K31/56 A61L2/00 C07J5/00

    摘要: The present invention provides a method for the sterilization of a labile glucocorticosteroid, which method comprises heat-treating by moist heat the labile glucocorticosteroid in the form of a suspension for a sterilizing-effective time. The methods and compositions according to the invention are useful as therapeutic tools to prevent, reverse, and/or reduce the symptoms of allergic and/or inflammatory conditions in a mammalian patient. The invention also provides methods and compositions, which may be manipulated and fine-tuned to fit the condition(s) to be treated while producing fewer side effects.

    摘要翻译: 本发明提供了一种灭活不稳定糖皮质激素的方法,该方法包括以悬浮液的形式将不稳定的糖皮质激素通过湿热加热灭菌有效时间。 根据本发明的方法和组合物可用作预防,逆转和/或减少哺乳动物患者的过敏和/或炎症状况的治疗工具。 本发明还提供方法和组合物,其可以被操纵和微调以适应待治疗的状况,同时产生更少的副作用。

    GAME OF CHANCE
    10.
    发明申请
    GAME OF CHANCE 失效
    魔术游戏

    公开(公告)号:US20100120513A1

    公开(公告)日:2010-05-13

    申请号:US12268878

    申请日:2008-11-11

    IPC分类号: A63F9/24 A63F13/00

    CPC分类号: G07F17/32 G07F17/3286

    摘要: A game of chance includes receiving a stake corresponding to a target game-item from a player. In each phase of the game, a random integer is selected and a game-item corresponding to that integer is removed from play. If the target game-item is removed from play, the player is awarded a return and the game of chance ends. If specific game-items or combinations of game items are removed from play, the player is defeated, and the game of chance ends. A subsequent phase of the game of chance begins if the player is not defeated or awarded a return.

    摘要翻译: 游戏机会包括从玩家接收与目标游戏项目相对应的投注。 在游戏的每个阶段中,选择随机整数,并且从游戏中去除与该整数相对应的游戏项目。 如果目标游戏项目从游戏中移除,玩家将获得回报并且机会游戏结束。 如果特定游戏项目或游戏项目的组合从游戏中移除,则玩家被击败,并且机会游戏结束。 如果玩家没有被打败或者获得回报,那么游戏的后续阶段就会开始。