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    STIMULATION OF SATIETY HORMONE RELEASE
    5.
    发明申请
    STIMULATION OF SATIETY HORMONE RELEASE 审中-公开
    刺激激素释放激素

    公开(公告)号：US20130035559A1

    公开(公告)日：2013-02-07

    申请号：US13464470

    申请日：2012-05-04

    申请人： Pamela J. Hornby ,  Tatiana Ort ,  Radhika Kajekar ,  Paul R. Wade

    发明人： Pamela J. Hornby ,  Tatiana Ort ,  Radhika Kajekar ,  Paul R. Wade

    IPC分类号： A61M37/00 ,  A61B5/145 ,  A61B5/05

    CPC分类号： A61N1/36007

    摘要： The present invention provides a site specific way to enhance a natural hormonal response to nutrients entering the small intestine after gastric emptying, thereby providing therapeutic value for obesity or diabetic patients. In one aspect, the present invention provides methods of stimulating the release of satiety hormone in a subject comprising applying a first electrical stimulus to a tissue in the lumen of the gastrointestinal system of the subject contemporaneously with the contacting of L-cells of the tissue with a nutrient stimulus. The present invention also provides methods for predicting patient response to a weight loss surgery comprising applying a first electrical stimulus to a tissue of the gastrointestinal system of said patient contemporaneously with the contacting of L-cells of the tissue with a nutrient stimulus, assessing the effect of the electrical stimulus in said patient, and, correlating said effect to said patient's response to a weight loss surgery.

    摘要翻译： 本发明提供了一种在胃排空后增强对进入小肠的营养物的天然激素反应的位点特异性方法，从而为肥胖症或糖尿病患者提供治疗价值。 一方面，本发明提供刺激受试者中饱腹感激素释放的方法，其包括将第一次电刺激施用于受试者的胃肠系统的内腔中的组织，同时使组织的L细胞与 营养刺激。 本发明还提供了用于预测患者对减肥手术的反应的方法，其包括将所述患者的胃肠系统的组织同时与组织的L细胞接触营养刺激施加第一电刺激，评估效果 的所述患者的电刺激，并且将所述效果与所述患者对减肥手术的反应相关联。

    Stimulation of Satiety Hormone Release
    6.
    发明申请
    Stimulation of Satiety Hormone Release 审中-公开
    刺激饱和激素释放

    公开(公告)号：US20100056948A1

    公开(公告)日：2010-03-04

    申请号：US12546721

    申请日：2009-08-25

    申请人： Pamela J. Hornby ,  Tatiana Ort ,  Radhika Kajekar ,  Paul R. Wade

    发明人： Pamela J. Hornby ,  Tatiana Ort ,  Radhika Kajekar ,  Paul R. Wade

    IPC分类号： A61N1/36 ,  G01N33/53 ,  A61B5/05

    CPC分类号： A61N1/36007

    摘要： The present invention provides, among other things, a site specific way to enhance a natural hormonal response to nutrients entering the small intestine after gastric emptying, thereby providing therapeutic value for obesity or diabetic patients. In one aspect, the present invention provides methods of stimulating the release of satiety hormone in a subject comprising applying a first electrical stimulus to a tissue in the lumen of the gastrointestinal system of the subject contemporaneously with the contacting of L-cells of the tissue with a nutrient stimulus. In another aspect, the present invention provides methods for predicting patient response to a weight loss surgery comprising applying a first electrical stimulus to a tissue of the gastrointestinal system of said patient contemporaneously with the contacting of L-cells of the tissue with a nutrient stimulus, assessing the effect of the electrical stimulus in said patient, and, correlating said effect to said patient's response to a weight loss surgery.

    摘要翻译： 本发明尤其提供了一种在胃排空后增强对进入小肠的营养物的天然激素反应的位点特异性方法，从而为肥胖症或糖尿病患者提供治疗价值。 在一个方面，本发明提供刺激受试者中饱腹感激素释放的方法，包括将第一次电刺激施用于患者的胃肠系统的内腔中的组织，同时使组织的L细胞与 营养刺激。 另一方面，本发明提供了用于预测患者对减肥手术的反应的方法，该方法包括：将第一电刺激与所述患者的胃肠系统的组织同时与组织的L细胞与营养刺激物接触， 评估所述患者的电刺激的影响，以及将所述效果与所述患者对减肥手术的反应相关联。

    Adjustable Warming Blanket
    7.
    发明申请
    Adjustable Warming Blanket 审中-公开

    公开(公告)号：US20180220493A1

    公开(公告)日：2018-08-02

    申请号：US15417801

    申请日：2017-01-27

    申请人： Paul R. Wade

    发明人： Paul R. Wade

    IPC分类号： H05B3/34

    CPC分类号： H05B3/342 ,  H05B3/34

    摘要： An adjustable warming blanket with a smooth, glossy fabric layer and a fabric layer made of a soft napped material, particularly useful for warming the extremities of an individual, the fabric layers forming a two-layer rectangular fabric structure utilizing a zipper arrangement to adjust the configuration and size of the blanket.

    Multi-level kennel enclosure with forced ventilation
    8.
    发明授权
    Multi-level kennel enclosure with forced ventilation 有权
    具有强制通风功能的多层狗舍

    公开(公告)号：US06318295B1

    公开(公告)日：2001-11-20

    申请号：US09532439

    申请日：2000-03-23

    申请人： Paul R. Wade

    发明人： Paul R. Wade

    IPC分类号： A01K102

    CPC分类号： A01K1/03 ,  A01K1/033

    摘要： A multi-level kennel enclosure includes a structure formed by left and right side walls, top and bottom walls and back and front walls defining an interior. A shelf is mounted in the interior so as to divide the interior into an upper section defining a living section and a separate lower section including a toilet section. An opening in the shelf allows an animal in the interior to pass between the living section and the toilet section. The front wall includes a pivotable first door selectively movable from a closed position to an open position to provide access to the living section. The front wall further includes a pivotable second door selectively movable from a closed position to an open position to provide access to the toilet section. The front wall also includes a ventilation panel through which air can flow into the interior. A plurality of additional shelves divide the interior into a plurality of levels through which an animal can pass. The toilet section defines a space to accommodate a receptacle for holding waste deposited by the animal. A forced ventilation system including a ventilation passage vents unpleasant odors from the enclosure. A plurality of multi-level kennel enclosures can be arranged side by side with their ventilation passages in alignment to form a continuous ventilation duct.

    摘要翻译： 一个多层面的小屋外壳包括由左右侧壁，顶壁和底壁以及限定内部的后壁和前壁形成的结构。 搁板安装在内部，以便将内部分成限定活动部分的上部部分和包括马桶部分的单独的下部部分。 架子上的一个开口允许内部的动物通过生活部分和马桶部分之间。 前壁包括可选择性地从闭合位置移动到打开位置的可枢转的第一门，以提供通向生活部分的通路。 前壁还包括可枢转的第二门，其可选择性地从关闭位置移动到打开位置，以提供通向马桶部分的通路。 前壁还包括通风面板，空气可以通过该面板流入内部。 多个附加的货架将内部分成动物可以通过的多个水平。 马桶部分限定了容纳用于容纳由动物沉积的废物的容器的空间。 包括通风通道的强制通风系统从外壳排出不愉快的气味。 并排布置多个多层的狗舍式外壳，其通风通道对准，形成连续通风管道。

    MULTI-BURNER HIGH-PRESSURE PORTABLE STOVE HAVING INDEPENDENTLY CONTROLLED REGULATORS
    9.
    发明申请
    MULTI-BURNER HIGH-PRESSURE PORTABLE STOVE HAVING INDEPENDENTLY CONTROLLED REGULATORS 有权
    具有独立控制调节器的多燃烧器高压便携式炉

    公开(公告)号：US20140137850A1

    公开(公告)日：2014-05-22

    申请号：US13681708

    申请日：2012-11-20

    申请人： Stevenson Bert Wylde ,  Paul R. Wade

    发明人： Stevenson Bert Wylde ,  Paul R. Wade

    IPC分类号： F24C3/14

    CPC分类号： F24C3/14 ,  F24C3/126 ,  Y02B40/166

    摘要： A multi-burner high-pressure portable stove having independently regulated burners is provided. The stove is especially suitable for camping. The stove provides similar functionality as a typical kitchen range by allowing a user to efficiently control the amount of fuel utilized by each individual burner of the stove. The stove further allows the user to independently control varying flame amounts of each burner so as a user may select between, simmer, medium, high or anything in-between for each burner. The regulators have a dual-lead stem thread knob which allows for quick and easy adjustments. The regulators are safely secured within a housing of the stove. In an embodiment, the regulators may be located outside the housing of the stove.

    摘要翻译： 提供具有独立调节燃烧器的多燃烧器高压便携式炉。 炉灶特别适合露营。 炉子通过允许使用者有效地控制炉子的每个燃烧器所使用的燃料量，提供与典型厨房范围相似的功能。 炉子进一步允许用户独立地控制每个燃烧器的变化的火焰量，以便用户可以在每个燃烧器之间选择煨，中，高或任何东西。 调节器具有双引线杆螺纹旋钮，可以快速方便地进行调节。 调节器安全地固定在炉子的外壳内。 在一个实施例中，调节器可以位于炉的壳体外部。