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公开(公告)号:US07825117B2
公开(公告)日:2010-11-02
申请号:US11374683
申请日:2006-06-27
IPC分类号: A61K31/53 , A61K31/50 , A61K31/513
CPC分类号: A61K31/513 , A61K31/53 , C07D239/545 , C07D251/46
摘要: The present invention relates to prokineticin 1 receptor antagonists and methods of using the same to modulate intestine epithelial functions and to treat inflammation in the intestine in a mammal.
摘要翻译: 本发明涉及原肌动蛋白1受体拮抗剂及其用途来调节肠上皮功能和治疗哺乳动物肠内炎症的方法。
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公开(公告)号:US20120245077A1
公开(公告)日:2012-09-27
申请号:US13429773
申请日:2012-03-26
CPC分类号: A61K31/513 , A61K31/53 , C07D239/545 , C07D251/46
摘要: The present invention relates to methods of monitoring the biological activity of the PK1 receptor.
摘要翻译: 本发明涉及监测PK1受体的生物学活性的方法。
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3.Methods of treating inflammation using prokineticin 1 receptor antagonists 有权
标题翻译: 使用促动蛋白1受体拮抗剂治疗炎症的方法公开(公告)号:US08188081B2
公开(公告)日:2012-05-29
申请号:US12797266
申请日:2010-06-09
CPC分类号: A61K31/513 , A61K31/53 , C07D239/545 , C07D251/46
摘要: The present invention relates to prokineticin 1 receptor antagonists and methods of using the same to modulate intestine epithelial functions and to treat inflammation in the intestine in a mammal.
摘要翻译: 本发明涉及原肌动蛋白1受体拮抗剂及其用途来调节肠上皮功能和治疗哺乳动物肠内炎症的方法。
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公开(公告)号:US20110136811A1
公开(公告)日:2011-06-09
申请号:US12797266
申请日:2010-06-09
IPC分类号: A61K31/53 , A61K31/513 , A61P29/00 , A61P1/00
CPC分类号: A61K31/513 , A61K31/53 , C07D239/545 , C07D251/46
摘要: The present invention relates to methods of monitoring the biological activity of the PK1 receptor.
摘要翻译: 本发明涉及监测PK1受体的生物学活性的方法。
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5.
公开(公告)号:US07812121B2
公开(公告)日:2010-10-12
申请号:US11848635
申请日:2007-08-31
申请人: Audrey E. Baker , Beverly A. Moore , Thomas Nesspor , Karyn O'Neil , Jeffrey M. Palmer , Kristen Picha , Sarah Sague
发明人: Audrey E. Baker , Beverly A. Moore , Thomas Nesspor , Karyn O'Neil , Jeffrey M. Palmer , Kristen Picha , Sarah Sague
IPC分类号: A61K38/16
CPC分类号: C07H21/04 , C07K14/605 , C07K2317/622 , C07K2319/30
摘要: Mammalian GLP-2 mimetibodies, polypeptides and nucleic acids are disclosed. Methods of utilizing the mimetibodies and polypeptides to treat GLP-2 related diseases are also disclosed.
摘要翻译: 公开了哺乳动物GLP-2模拟物,多肽和核酸。 还公开了利用模拟抗体和多肽来治疗GLP-2相关疾病的方法。
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6.GLP-2 Mimetibodies, Polypeptides, Compositions, Methods and Uses 有权
标题翻译: GLP-2 Mimetibodies,Polypeptides,Compositions,Methods and Uses公开(公告)号:US20090117104A1
公开(公告)日:2009-05-07
申请号:US11848635
申请日:2007-08-31
申请人: Audrey E. Baker , Beverly A. Moore , Thomas Nesspor , Karyn O'Neil , Jeffrey M. Palmer , Kristen Picha , Sarah Sague
发明人: Audrey E. Baker , Beverly A. Moore , Thomas Nesspor , Karyn O'Neil , Jeffrey M. Palmer , Kristen Picha , Sarah Sague
IPC分类号: A61K39/395 , C07K16/00 , C07H21/04 , C12N15/64 , A61K38/16 , A61P1/00 , C07K14/00 , C12N5/16 , C12P21/00
CPC分类号: C07H21/04 , C07K14/605 , C07K2317/622 , C07K2319/30
摘要: Mammalian GLP-2 mimetibodies, polypeptides and nucleic acids are disclosed. Methods of utilizing the mimetibodies and polypeptides to treat GLP-2 related diseases are also disclosed.
摘要翻译: 公开了哺乳动物GLP-2模拟物,多肽和核酸。 还公开了利用模拟抗体和多肽来治疗GLP-2相关疾病的方法。
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