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    Adaptive windowing for cardiac waveform discrimination
    2.
    发明授权
    Adaptive windowing for cardiac waveform discrimination 有权
    心脏波形鉴别的自适应窗口

    公开(公告)号：US08145296B2

    公开(公告)日：2012-03-27

    申请号：US12538297

    申请日：2009-08-10

    申请人： Kevin J. Stalsberg ,  Yanting Dong ,  Scott Meyer ,  Eric K. Enrooth ,  Derek D. Bohn

    发明人： Kevin J. Stalsberg ,  Yanting Dong ,  Scott Meyer ,  Eric K. Enrooth ,  Derek D. Bohn

    IPC分类号： A61B5/042

    CPC分类号： A61N1/371 ,  A61B5/04525 ,  A61B5/0472 ,  A61B5/7217

    摘要： Cardiac devices and methods provide adaptation of detection windows used to determine a cardiac response to pacing. Adapting a detection window involves sensing a cardiac signal indicative of a particular type of cardiac pacing response, and detecting a feature of the sensed cardiac signal. The cardiac response detection window associated with the type of cardiac pacing response is preferentially adjusted based on the location of the detected cardiac feature. Preferential adjustment of the detection window may involve determining a direction of change between the detection window and the detected feature. The detection window may be adapted more aggressively in a more preferred direction and less aggressively in a less preferred direction.

    摘要翻译： 心脏装置和方法提供用于确定对起搏的心脏反应的检测窗口的适应。 适应检测窗口包括感测指示特定类型的心脏起搏反应的心脏信号，以及检测感测到的心脏信号的特征。 基于检测到的心脏特征的位置优先调整与心脏起搏响应类型相关联的心脏响应检测窗口。 检测窗口的优先调整可以包括确定检测窗口和检测到的特征之间的变化方向。 检测窗口可以在更优选的方向上更积极地改变，并且在较不优选的方向上较不积极地适配。

    Methods and systems for managing fusion and noise in cardiac pacing response classification
    4.
    发明申请
    Methods and systems for managing fusion and noise in cardiac pacing response classification 有权
    用于管理心脏起搏反应分类中的融合和噪声的方法和系统

    公开(公告)号：US20060247695A1

    公开(公告)日：2006-11-02

    申请号：US11116565

    申请日：2005-04-28

    申请人： Kevin Stalsberg ,  Yanting Dong ,  Scott Meyer ,  John Voegele ,  Derek Bohn ,  Eric Enrooth ,  Clayton Foster ,  David Yost

    发明人： Kevin Stalsberg ,  Yanting Dong ,  Scott Meyer ,  John Voegele ,  Derek Bohn ,  Eric Enrooth ,  Clayton Foster ,  David Yost

    IPC分类号： A61N1/362

    CPC分类号： A61N1/371 ,  A61B5/0452 ,  A61B5/7203 ,  A61B5/7217 ,  A61B5/7264

    摘要： Methods and systems for detecting noise in cardiac pacing response classification processes involve determining that a cardiac response classification is possibly erroneous if unexpected signal content is detected. The unexpected signal content may comprise signal peaks that have polarity opposite to the polarity of peaks used to determine the cardiac response to pacing. Fusion/noise management processes include pacing at a relatively high energy level until capture is detected after a fusion, indeterminate or possibly erroneous pacing response classification is made. The relatively high energy pacing pulses may be delivered until capture is detected or until a predetermined number of paces are delivered.

    摘要翻译： 用于检测心脏起搏反应分类过程中的噪声的方法和系统涉及如果检测到意外的信号内容，则确定心脏反应分类可能是错误的。 意想不到的信号内容可以包括具有与用于确定对起搏的心脏反应的峰的极性相反的极性的信号峰。 融合/噪声管理过程包括在相对较高的能量级别进行起搏，直到在融合之后检测到捕获，进行不确定或可能错误的起搏响应分类。 可以递送相对高的能量起搏脉冲，直到检测到捕获或直到传送预定数量的步数。

    Rate Initialization and Overdrive Pacing for Capture Threshold Testing
    5.
    发明申请
    Rate Initialization and Overdrive Pacing for Capture Threshold Testing 有权
    速率初始化和超速起搏用于捕获阈值测试

    公开(公告)号：US20120165897A1

    公开(公告)日：2012-06-28

    申请号：US13306615

    申请日：2011-11-29

    申请人： Eric K. Enrooth ,  Sunipa Saha ,  Clayton Foster ,  Yanting Dong

    发明人： Eric K. Enrooth ,  Sunipa Saha ,  Clayton Foster ,  Yanting Dong

    IPC分类号： A61N1/37

    CPC分类号： A61N1/371 ,  A61N1/3714

    摘要： Approaches for rate initialization and overdrive pacing used during capture threshold testing are described. Cardiac cycles are detected and the cardiac events of a cardiac chamber that occur during the cardiac cycles are monitored. The number of intrinsic beats in the cardiac events is counted. Initialization for a capture threshold test involves maintaining a pre-test pacing rate for the capture threshold test if the number of intrinsic beats in the cardiac events is less than a threshold. The pacing rate is increased for the capture threshold test if the number of intrinsic beats in the cardiac events is greater than the threshold.

    摘要翻译： 描述捕获阈值测试期间使用的速率初始化和超速起搏的方法。 检测到心脏周期，并监测在心脏周期期间发生的心室的心脏事件。 计数心脏事件中的固有搏动次数。 捕获阈值测试的初始化涉及如果心脏事件中的固有搏动次数小于阈值，则保持捕获阈值测试的预先测试起搏速率。 如果心脏事件中的固有搏动次数大于阈值，则针对捕获阈值测试，起搏速率将增加。

    Adjusting Cardiac Pacing Response Sensing Intervals
    6.
    发明申请
    Adjusting Cardiac Pacing Response Sensing Intervals 审中-公开
    调整心脏起搏反应感测间隔

    公开(公告)号：US20120303082A1

    公开(公告)日：2012-11-29

    申请号：US13306611

    申请日：2011-11-29

    申请人： Yanting Dong ,  Shibaji Shome ,  Aaron McCabe ,  Amy J. Brisben ,  Clayton Foster ,  David W. Yost ,  Kenneth N. Hayes

    发明人： Yanting Dong ,  Shibaji Shome ,  Aaron McCabe ,  Amy J. Brisben ,  Clayton Foster ,  David W. Yost ,  Kenneth N. Hayes

    IPC分类号： A61N1/37 ,  A61N1/365

    CPC分类号： A61N1/371 ,  A61B5/0422 ,  A61B5/04525 ,  A61B5/0456 ,  A61B5/4836 ,  A61B5/7217 ,  A61B5/7267 ,  A61N1/3712

    摘要： Discrimination between different types of possible cardiac pacing responses may depend on the timing of expected features that are sensed within a temporal framework. The temporal framework may include classification intervals, blanking periods and appropriately timed back up paces. The classification intervals and blanking periods of the temporal framework are intervals of time that have time parameters that include start time, end time, and length. The relationships and timing parameters of the elements of the temporal framework, e.g., blanking periods, classification intervals, delay periods, and backup pacing, should support detection of features used to discriminate between different types of pacing responses. As the system learns the morphology of the particular patient by analyzing the waveform of the pacing response signal, the temporal framework for pacing response determination may be adjusted to accommodate the individual patient.

    摘要翻译： 不同类型的可能心脏起搏反应之间的歧视可能取决于在时间框架内感测到的预期特征的时间。 时间框架可以包括分类间隔，消隐期和适当定时的后台步数。 时间框架的分类间隔和消隐期是具有包括开始时间，结束时间和长度的时间参数的时间间隔。 时间框架的元素的关系和定时参数，例如消隐期，分类间隔，延迟周期和备份起搏应该支持用于区分不同类型的起搏响应的特征的检测。 当系统通过分析起搏响应信号的波形来学习特定患者的形态时，可调整起搏响应确定的时间框架以适应个体患者。

    Cardiac response classification using retriggerable classification windows
    7.
    发明申请
    Cardiac response classification using retriggerable classification windows 有权
    使用可重新触发分类窗口的心脏反应分类

    公开(公告)号：US20050131477A1

    公开(公告)日：2005-06-16

    申请号：US10734599

    申请日：2003-12-12

    申请人： Scott Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

    发明人： Scott Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

    IPC分类号： A61B5/04 ,  A61B5/0452 ,  A61N1/37

    CPC分类号： A61B5/7264 ,  A61B5/04525 ,  A61B5/7217 ,  A61N1/371

    摘要： Methods and devices for classifying a cardiac response to pacing involve establishing a retriggerable cardiac response classification window. A first cardiac response classification window is established subsequent to delivery of a pacing pulse. A cardiac signal following the pacing stimulation is sensed in the first classification window. A second cardiac response classification may be triggered if a trigger characteristic is detected in the first classification window. The cardiac signal is sensed in the second classification window if the second classification window is established. The cardiac response to the pacing stimulation is determined based on characteristics of the cardiac signal. The cardiac response may be determined to be one of a captured response, a non-captured response; a non-captured response added to an intrinsic beat, and a fusion/pseudofusion beat, for example.

    摘要翻译： 用于分类心脏起搏应答的方法和装置包括建立可再触发的心脏反应分类窗口。 在递送起搏脉冲之后建立第一心脏响应分类窗口。 起搏刺激后的心脏信号在第一分类窗口中被感测。 如果在第一分类窗口中检测到触发特性，则可以触发第二心跳响应分类。 如果建立第二分类窗口，则在第二分类窗口中感测到心脏信号。 基于心脏信号的特征确定对起搏刺激的心脏反应。 心脏反应可以被确定为捕获的应答，非捕获的响应之一; 例如，添加到固有节拍的非捕获响应以及融合/假融合节拍。

    Methods and Systems for Mitigating the Occurrence of Arrhythmia During Atrial Pacing
    8.
    发明申请
    Methods and Systems for Mitigating the Occurrence of Arrhythmia During Atrial Pacing 有权
    心房起搏减轻心律失常发生的方法和系统

    公开(公告)号：US20100286743A1

    公开(公告)日：2010-11-11

    申请号：US12772725

    申请日：2010-05-03

    申请人： Eric K. Enrooth ,  Yanting Dong ,  Kenneth N. Hayes ,  Gary T. Seim ,  Kevin John Stalsberg ,  Aaron McCabe

    发明人： Eric K. Enrooth ,  Yanting Dong ,  Kenneth N. Hayes ,  Gary T. Seim ,  Kevin John Stalsberg ,  Aaron McCabe

    IPC分类号： A61N1/37

    CPC分类号： A61N1/3712 ,  A61N1/3622 ,  A61N1/3714

    摘要： Noncaptured atrial paces can result in long-short cardiac cycles which are proarrhythmic for ventricular tachyarrhythmia. Approaches are described which are directed to avoiding proarrhythmic long-short cycles. For cardiac cycles in which the atrial pace captures the atrium, a first post ventricular refractory period (PVARP) and a first A-A interval are used. For cardiac cycles in which the atrial pace does not capture the atrium, both an extended PVARP and an extended A-A interval are used. The A-A interval following a noncaptured atrial pace is extended from an atrial depolarization sensed during the extended PVARP.

    摘要翻译： 非心房颤动可导致心律失常的心律失常的长时间心脏周期。 描述了旨在避免心律失常长时间短周期的方法。 对于心房搏动捕获心房的心脏周期，使用第一个心室后不应期（PVARP）和第一个A-A间隔。 对于其中心房速度不捕获心房的心脏周期，使用延长的PVARP和延长的A-A间隔。 在非扩张性PVARP期间感觉到的心房去极化之后，A-A间隔未被捕获。

    Rate initialization and overdrive pacing for capture threshold testing
    9.
    发明授权
    Rate initialization and overdrive pacing for capture threshold testing 有权
    速率初始化和超速起搏用于捕获阈值测试

    公开(公告)号：US08725261B2

    公开(公告)日：2014-05-13

    申请号：US13306615

    申请日：2011-11-29

    申请人： Eric K. Enrooth ,  Sunipa Saha ,  Clayton S. Foster ,  Yanting Dong

    发明人： Eric K. Enrooth ,  Sunipa Saha ,  Clayton S. Foster ,  Yanting Dong

    IPC分类号： A61N1/362

    CPC分类号： A61N1/371 ,  A61N1/3714

    摘要： Approaches for rate initialization and overdrive pacing used during capture threshold testing are described. Cardiac cycles are detected and the cardiac events of a cardiac chamber that occur during the cardiac cycles are monitored. The number of intrinsic beats in the cardiac events is counted. Initialization for a capture threshold test involves maintaining a pre-test pacing rate for the capture threshold test if the number of intrinsic beats in the cardiac events is less than a threshold. The pacing rate is increased for the capture threshold test if the number of intrinsic beats in the cardiac events is greater than the threshold.

    摘要翻译： 描述捕获阈值测试期间使用的速率初始化和超速起搏的方法。 检测到心脏周期，并监测在心脏周期期间发生的心室的心脏事件。 计数心脏事件中的固有搏动次数。 捕获阈值测试的初始化涉及如果心脏事件中的固有搏动次数小于阈值，则保持捕获阈值测试的预先测试起搏速率。 如果心脏事件中的固有搏动次数大于阈值，则针对捕获阈值测试，起搏速率将增加。

    Pacing interval adjustment for cardiac pacing response determination
    10.
    发明授权
    Pacing interval adjustment for cardiac pacing response determination 有权
    心脏起搏反应确定的起搏间隔调整

    公开(公告)号：US08364264B2

    公开(公告)日：2013-01-29

    申请号：US11242240

    申请日：2005-10-03

    申请人： Scott A. Meyer ,  Yanting Dong ,  Kevin J. Stalsberg ,  Alok Sathaye

    发明人： Scott A. Meyer ,  Yanting Dong ,  Kevin J. Stalsberg ,  Alok Sathaye

    IPC分类号： A61N1/362

    CPC分类号： A61N1/371 ,  A61B5/04525 ,  A61B5/7217 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3712

    摘要： The waveform morphology of a propagated pacing response signal may be adjusted to achieve a waveform morphology that enhances cardiac pacing response determination. One or more pacing intervals may be adjusted to achieve at least one cardiac pacing response waveform morphology that enhances determination of the cardiac pacing response. The heart is paced using the one or more adjusted pacing intervals and the cardiac response to the pacing is determined. The one or more adjusted pacing intervals may include an atrioventricular pacing delay, an interatrial pacing delay, an interventricular pacing delay, or other inter-chamber or inter-site pacing delays. Adjusting the one or more pacing intervals may be used to increase a difference between a first waveform morphology associated with multi-chamber capture and a second waveform morphology associated with single chamber capture.

    摘要翻译： 可以调节传播的起搏响应信号的波形形态，以实现增强心脏起搏响应确定的波形形态。 可以调整一个或多个起搏间隔以实现至少一个心脏起搏响应波形形态，其增强心脏起搏响应的确定。 心脏使用一个或多个调整的起搏间隔进行起搏，并且确定对起搏的心脏反应。 一个或多个调整的起搏间隔可以包括房室起搏延迟，房间起搏延迟，室间起搏延迟或其他间室间或间部间起搏延迟。 可以使用调整一个或多个起搏间隔来增加与多室捕获相关联的第一波形形态与与单室捕获相关联的第二波形形态之间的差异。