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    System and method for adjustment of blood separation procedure parameters
    1.
    发明授权
    System and method for adjustment of blood separation procedure parameters 有权
    血液分离手术参数调整系统及方法

    公开(公告)号：US08852140B2

    公开(公告)日：2014-10-07

    申请号：US13345305

    申请日：2012-01-06

    申请人： John W. Barry, Jr. ,  Brian C. Case ,  Lan T. Nguyen

    发明人： John W. Barry, Jr. ,  Brian C. Case ,  Lan T. Nguyen

    IPC分类号： B01D17/12 ,  B01D17/00 ,  B01D43/00 ,  A61M1/36

    CPC分类号： A61M1/3693 ,  A61M1/0209 ,  A61M1/3672 ,  A61M2202/0427

    摘要： Systems and methods are provided for automatically adjusting the operational parameters of a blood separation procedure. A blood separation device has an inlet for passing fluid thereinto and an outlet for removing fluid therefrom. A pump system is provided for moving fluid into and out of the device. In use, blood is conveyed into the device, where platelets are separated from at least a portion of the blood. A controller determines the amount of platelets in the device. Based at least in part on the amount of platelets in the device, corrective action is taken to avoid platelet aggregation in the device. The corrective action may be conveying an elevated amount of anticoagulant into the blood and/or the device and may be initiated when the determined amount of platelets approaches, meets, or exceeds a threshold predicted likelihood of platelet aggregation.

    摘要翻译： 提供了用于自动调整血液分离程序的操作参数的系统和方法。 血液分离装置具有用于使流体流入的入口和用于从其中除去流体的出口。 提供用于将流体移入和移出设备的泵系统。 在使用中，将血液输送到装置中，其中血小板与至少一部分血液分离。 控制器确定设备中血小板的量。 至少部分地基于装置中的血小板的量，采取纠正措施以避免装置中的血小板聚集。 纠正措施可能是将升高量的抗凝血剂输送到血液和/或装置中，并且可以在所确定的血小板接近，满足或超过血小板聚集的阈值预测可能性时开始。

    SYSTEM AND METHOD FOR ADJUSTMENT OF BLOOD SEPARATION PROCEDURE PARAMETERS
    2.
    发明申请
    SYSTEM AND METHOD FOR ADJUSTMENT OF BLOOD SEPARATION PROCEDURE PARAMETERS 有权
    用于调节血液分离程序参数的系统和方法

    公开(公告)号：US20120175313A1

    公开(公告)日：2012-07-12

    申请号：US13345305

    申请日：2012-01-06

    申请人： John W. Barry, JR. ,  Brian C. Case ,  Lan T. Nguyen

    发明人： John W. Barry, JR. ,  Brian C. Case ,  Lan T. Nguyen

    IPC分类号： B01D17/12 ,  B01D43/00 ,  B01D17/00

    CPC分类号： A61M1/3693 ,  A61M1/0209 ,  A61M1/3672 ,  A61M2202/0427

    摘要： Systems and methods are provided for automatically adjusting the operational parameters of a blood separation procedure. A blood separation device has an inlet for passing fluid thereinto and an outlet for removing fluid therefrom. A pump system is provided for moving fluid into and out of the device. In use, blood is conveyed into the device, where platelets are separated from at least a portion of the blood. A controller determines the amount of platelets in the device. Based at least in part on the amount of platelets in the device, corrective action is taken to avoid platelet aggregation in the device. The corrective action may be conveying an elevated amount of anticoagulant into the blood and/or the device and may be initiated when the determined amount of platelets approaches, meets, or exceeds a threshold predicted likelihood of platelet aggregation.

    摘要翻译： 提供了用于自动调整血液分离程序的操作参数的系统和方法。 血液分离装置具有用于使流体流入的入口和用于从其中除去流体的出口。 提供用于将流体移入和移出设备的泵系统。 在使用中，将血液输送到装置中，其中血小板与至少一部分血液分离。 控制器确定设备中血小板的量。 至少部分地基于装置中的血小板的量，采取纠正措施以避免装置中的血小板聚集。 纠正措施可能是将升高量的抗凝血剂输送到血液和/或装置中，并且可以在所确定的血小板接近，满足或超过血小板聚集的阈值预测可能性时开始。

    SYSTEMS AND METHODS FOR USE AND CONTROL OF AN AUTOMATED SEPARATOR WITH ADSORPTION COLUMNS
    3.
    发明申请
    SYSTEMS AND METHODS FOR USE AND CONTROL OF AN AUTOMATED SEPARATOR WITH ADSORPTION COLUMNS 有权
    具有吸附柱的自动分离器的使用和控制的系统和方法

    公开(公告)号：US20140291248A1

    公开(公告)日：2014-10-02

    申请号：US14110587

    申请日：2011-04-13

    申请人： John T. Foley ,  Jonathan Prendergast ,  Lan T. Nguyen ,  Brian C. Case

    发明人： John T. Foley ,  Jonathan Prendergast ,  Lan T. Nguyen ,  Brian C. Case

    IPC分类号： A61M1/36

    CPC分类号： A61M1/362 ,  A61M1/3639 ,  A61M1/3641 ,  A61M1/3663 ,  A61M1/3679 ,  A61M1/3693 ,  A61M1/3696

    摘要： Blood treatment systems and methods are provided for combining a blood separation system and an adsorption device. The blood separation system is configured to separate a blood component from blood, while the adsorption device is configured to receive at least a portion of the separated blood component and process it. The blood separation system includes a fluid flow element and a controller. The fluid flow element is configured for flowing the separated blood component into the adsorption device. The controller controls the fluid flow element based at least in part on one or more processing parameters. The processing parameters include a maximum flow rate of the separated blood component flowed into the adsorption device, a maximum pressure of the separated blood component flowed into the adsorption device, and/or the volume of fluid in a location of the system.

    摘要翻译： 提供血液处理系统和方法用于组合血液分离系统和吸附装置。 血液分离系统被配置为将血液成分与血液分离，而吸附装置构造成接收至少一部分分离的血液成分并进行处理。 血液分离系统包括流体流动元件和控制器。 流体流动元件构造成使分离的血液成分流入吸附装置。 控制器至少部分地基于一个或多个处理参数来控制流体流动元件。 处理参数包括流入吸附装置的分离的血液成分的最大流量，流入吸附装置的分离的血液成分的最大压力和/或系统位置的流体体积。

    Systems and methods for use and control of an automated separator with adsorption columns
    4.
    发明授权
    Systems and methods for use and control of an automated separator with adsorption columns 有权

    公开(公告)号：US10413652B2

    公开(公告)日：2019-09-17

    申请号：US14110587

    申请日：2011-04-13

    申请人： John T. Foley ,  Jonathan Prendergast ,  Lan T. Nguyen ,  Brian C. Case

    发明人： John T. Foley ,  Jonathan Prendergast ,  Lan T. Nguyen ,  Brian C. Case

    IPC分类号： A61M1/36

    摘要： Blood treatment systems and methods are provided for combining a blood separation system and an adsorption device. The blood separation system is configured to separate a blood component from blood, while the adsorption device is configured to receive at least a portion of the separated blood component and process it. The blood separation system includes a fluid flow element and a controller. The fluid flow element is configured for flowing the separated blood component into the adsorption device. The controller controls the fluid flow element based at least in part on one or more processing parameters. The processing parameters include a maximum flow rate of the separated blood component flowed into the adsorption device, a maximum pressure of the separated blood component flowed into the adsorption device, and/or the volume of fluid in a location of the system.

    SYSTEM AND METHOD TO BETTER ASSURE CORRECT USE OF PRE-PROGRAMMED MEDICAL DEVICES
    5.
    发明申请
    SYSTEM AND METHOD TO BETTER ASSURE CORRECT USE OF PRE-PROGRAMMED MEDICAL DEVICES 审中-公开
    更好地确保预编程医疗设备的正确使用的系统和方法

    公开(公告)号：US20120297255A1

    公开(公告)日：2012-11-22

    申请号：US13110520

    申请日：2011-05-18

    申请人： Brian C. Case ,  Lan T. Nguyen

    发明人： Brian C. Case ,  Lan T. Nguyen

    IPC分类号： G06F11/07

    CPC分类号： G16H40/60 ,  A61B34/10 ,  A61M1/34 ,  A61M1/3403 ,  A61M2205/33 ,  A61M2205/3334 ,  G06F19/00 ,  G06F21/31 ,  G08B3/10 ,  G08B5/22 ,  G16H10/60 ,  H05K999/99

    摘要： Systems and methods are provided for performing a medical procedure with respect to a subject. A data storage location of the system is pre-programmed with a plurality of subject data entries, each having subject-specific information associated with it. A user interface receives an identity input from a subject, which corresponds to the identity of the subject. A controller is associated with the database and the user interface, and is programmed to compare the identity input to the subject data entries. If the identity input corresponds to the subject-specific information of a subject data entry, the controller commands a treatment device to perform a medical procedure with respect to the subject. Otherwise, if the identity input does not correspond to the subject-specific information of any of the subject data entries, the controller generates an error signal which prevents the performance of the medical procedure with respect to the subject.

    摘要翻译： 提供了用于执行关于受试者的医疗程序的系统和方法。 系统的数据存储位置用多个对象数据条目进行预编程，每个对象数据条目具有与其相关联的对象特定信息。 用户界面从对象接收与被摄体的身份相对应的身份输入。 控制器与数据库和用户界面相关联，并被编程为将身份输入与主题数据条目进行比较。 如果身份输入对应于对象数据条目的被摄体特定信息，则控制器命令治疗装置对被摄体进行医疗处理。 否则，如果身份输入不对应于任何主题数据条目的主题特定信息，则控制器产生阻止相对于被摄体执行医疗程序的错误信号。

    Automatic lock for telescoping joint of a riser system
    7.
    发明授权
    Automatic lock for telescoping joint of a riser system 有权
    立管系统的伸缩接头的自动锁定

    公开(公告)号：US06334633B1

    公开(公告)日：2002-01-01

    申请号：US09193884

    申请日：1998-11-18

    申请人： Lan T. Nguyen ,  Scott D. Ward ,  Roger Boisjolie

    发明人： Lan T. Nguyen ,  Scott D. Ward ,  Roger Boisjolie

    IPC分类号： F16L2108

    CPC分类号： F16L37/0848 ,  E21B17/07 ,  E21B19/004 ,  F16L37/62 ,  Y10S285/92

    摘要： An automatic locking mechanism for a telescoping joint for a riser functions in several modes. In an operating mode, the joint is free to have its inner and outer barrels move with respect to each other without engaging each other in a locking relationship. In a second position, the telescoping joint locks when it is fully retracted. In a third position, the system locks the inner and outer barrels together to hold them in a fixed position. The inner and outer barrels are locked when a movable sleeve is properly positioned to allow spring-loaded dogs to be biased through windows in the sleeve so as to act as a landing shoulder to catch a groove on the outer barrel. By putting the actuating sleeve in a variety of positions, the various modes of the locking assembly can be deployed.

    摘要翻译： 用于立管的伸缩接头的自动锁定机构在几种模式中起作用。 在操作模式中，接头可自由地使其内桶和外桶彼此相对移动，而不会相互锁定。 在第二位置，伸缩接头在完全缩回时锁定。 在第三位置，系统将内桶和外桶锁定在一起以将它们保持在固定位置。 当可移动套筒被适当地定位以允许弹簧加载的狗通过套筒中的窗口偏置以便作为着陆台肩以抓住外筒上的凹槽时，内筒和外桶被锁定。 通过将致动套筒放置在各种位置，可以部署锁定组件的各种模式。

    Apparatus for reducing fastener bending stress in flanged connections
    8.
    发明授权
    Apparatus for reducing fastener bending stress in flanged connections 有权

    公开(公告)号：US06361085B1

    公开(公告)日：2002-03-26

    申请号：US09729746

    申请日：2000-12-05

    申请人： Lan T. Nguyen

    发明人： Lan T. Nguyen

    IPC分类号： F16L1900

    摘要： An apparatus for reducing the bending stress imparted to threaded fasteners in flanged connections is disclosed. The apparatus includes a radially tapered surface machined in the backface of the flanges to coact with the head of the threaded fastener as the threaded fastener is tightened to a predetermined torque value. This coaction compensates for flange deflection as the threaded fastener is tightened.

    Apparatus for reducing fastener bending stress in flanged connections
    9.
    发明授权
    Apparatus for reducing fastener bending stress in flanged connections 有权
    用于减少法兰连接中紧固件弯曲应力的装置

    公开(公告)号：US06176663B1

    公开(公告)日：2001-01-23

    申请号：US09216201

    申请日：1998-12-18

    申请人： Lan T. Nguyen ,  Stephen J. Walker

    发明人： Lan T. Nguyen ,  Stephen J. Walker

    IPC分类号： F16B3300

    CPC分类号： F16L23/036 ,  F16L23/003 ,  F16L23/006 ,  Y10S411/916

    摘要： An apparatus for reducing the bending stress imparted to threaded fasteners in flanged connections is disclosed. The apparatus includes a stress reducing washer positioned between the head of the threaded fastener and a counterbore in the backface of the flange. In a first embodiment, the stress reducing washer uses a tapered upper surface oriented with respect to the flange to compensate for flange deflection as the threaded fastener is tightened to a predetermined torque value. Second and third embodiments utilizing spherical and cylindrical surfaces are also shown. A fourth embodiment eliminates the need for the stress reducing washer and machines the tapered surface in the backface of the flange.

    摘要翻译： 公开了一种用于减小赋予法兰连接中的螺纹紧固件的弯曲应力的装置。 该装置包括位于螺纹紧固件的头部和凸缘的背面中的沉孔之间的应力减小垫圈。 在第一实施例中，应力减小垫圈使用相对于凸缘定向的锥形上表面，以补偿当螺纹紧固件被拧紧到预定扭矩值时的凸缘挠曲。 还示出了利用球形和圆柱形表面的第二和第三实施例。 第四实施例消除了对减压垫圈的需要，并且在凸缘背面加工锥形表面。