摘要:
A transdermal drug delivery device for forming a micropore in a tissue membrane of an animal comprising a substrate and a porator that is located on or within the substrate. The porator is constructed of a material that is destroyed upon forming the micropore. The transdermal drug delivery device also comprises at least one reservoir and a controller for controlling the formation of said micropore by the porator and destroying the porator after the formation of the micropore.
摘要:
An inert gas fuel consisting essentially of a precise, homogeneous mixture of helium, neon, argon, krypton and xenon. Apparatus for preparing the fuel includes a mixing chamber, tubing to allow movement of each inert gas into and through the various stages of the apparatus, a plurality of electric coils for producing magnetic fields, an ion gauge, ionizers, cathode ray tubes, filters, a polarizer and a high frequency generator. An engine for extracting useful work from the fuel has at least two closed cylinders for fuel, each cylinder being defined by a head and a piston. A plurality of electrodes extend into each chamber, some containing low level radioactive material. The head has a generally concave depression facing a generally semi-toroidal depression in the surface of the piston. The piston is axially movable with respect to the head from a first position to a second position and back, which linear motion is converted to rotary motion by a crankshaft. The engine's electrical system includes coils and condensers which circle each cylinder, an electric generator, and circuitry for controlling the flow of current within the system.
摘要:
The invention provides for improved devices and methods for forming openings in a biological membrane for delivering substances into an animal through the biological membrane for treatment applications, or extracting substances from the animal through the biological membrane for monitoring or other diagnosis applications and for increased transmembrane flux.
摘要:
A mechanical accumulator for holding and supplying a volume of hydraulic fluid under pressure comprising a variable volume fluid pressure chamber including a piston and a cylinder member, a plurality of coil springs acting on one of said members for biasing the same towards the other of said members to minimize the volume of said chamber and pressurize the fluid therein, a fluid conduit for directing pressurized fluid into and out of said chamber and switch means externally of said chamber and actuated by one of said members in response to the volume changes of said chamber for controlling the operation of a fluid device using fluid from the chamber.
摘要:
A method and device for forming artificial openings in a biological membrane with a pyrotechnic charge that is exploded in a controlled manner in proximity of the biological membrane to form the artificial opening(s) therein. The method and device are useful in connection with transdermal delivery and monitoring applications.
摘要:
A method and device for forming artificial openings in a biological membrane with a pyrotechnic charge that is exploded in a controlled manner in proximity of the biological membrane to form the artificial opening(s) therein. The method and device are useful in connection with transdermal delivery and monitoring applications.
摘要:
A novel bicycle neck has two sleeves disposed one over the other. A round handle-bar is rotatably mounted in each sleeve. The novel neck is placed into the front wheel fork of the bicycle after the standard prior art gooseneck has been removed. A flexible cable is attached by one end to the handle-bar in the upper sleeve so that the cable could be wound thereon by turning the handle-bar. The cable is then wound around the lower handle-bar and attached thereto to prevent slippage therebetween. The cable terminates at a whiffletree. Also attached to the whiffletree are two more cables disposed on opposite sides of the cable depending from the handle-bars. One of these other cables actuates the front wheel brakes, and the other actuates the rear wheel brakes when the cables are in tension. Tension is placed on the cables by rotating any one of the handle-bars within its respective sleeve.