公开(公告)号：US06303104B1

公开(公告)日：2001-10-16

申请号：US09249295

申请日：1999-02-12

申请人： Anthony E. Winston ,  Jordan Barth ,  Norman Usen

发明人： Anthony E. Winston ,  Jordan Barth ,  Norman Usen

IPC分类号： A61K716

CPC分类号： A61Q11/00 ,  A61K8/19 ,  A61K8/24 ,  A61K2800/88

摘要： An oral product, preferably a toothpaste, effective for remineralizing subsurface dental lesions, mineralizing exposed dentinal tubules and whitening teeth stained with discoloring residues containing heavy metal ions such as Fe+3, Mn+2 and Cu+2, is composed of a first discrete part composed of a water-soluble or partially water-soluble calcium salt and optionally a non-toxic, non-calcium water-soluble divalent metal salt, and a second discrete part composed of a water-soluble orthophosphate salt and preferably a water-soluble fluoride salt. Further enhanced stain-removing properties without excessive abrasivity are imparted to the oral product when part (A) further contains an effective amount of an anhydrous dicalcium phosphate abrasive and part (B) further contains an effective amount of a silica abrasive.

摘要翻译： 用于再矿化地下牙齿病变，矿化暴露的牙质小管和由含有重金属离子如Fe + 3，Mn + 2和Cu + 2的变色残渣染色的美白牙齿的口服产品，优选牙膏由第一离散 由水溶性或部分水溶性钙盐和任选的无毒非钙水溶性二价金属盐组成的部分，以及由水溶性正磷酸盐组成的第二离散部分，优选水溶性 氟化盐。 当部分（A）还含有有效量的无水磷酸二钙研磨剂时，口腔产品也能赋予进一步增强的除污性能，而不会过度磨损，部分（B）还含有有效量的二氧化硅磨料。

公开(公告)号：US06482395B1

公开(公告)日：2002-11-19

申请号：US10137317

申请日：2002-05-03

申请人： Jordan Barth ,  Anthony E. Winston ,  Norman Usen

发明人： Jordan Barth ,  Anthony E. Winston ,  Norman Usen

IPC分类号： A61K968

CPC分类号： A61Q11/00 ,  A61K8/19 ,  A61K8/24 ,  A61K2800/88

摘要： A solid oral product, e.g., chewing gum, lozenge, an edible foodstuff, and the like, which is useful for remineralizing subsurface dental lesions and/or mineralizing exposed dentinal tubules, contains (A) a discrete cationic agglomerate component composed of at least one water-soluble or partially water-soluble calcium salt and a first inert solid carrier, and (B) a discrete anionic agglomerate component composed of at least one water-soluble orthophosphate salt and a second inert solid carrier. The agglomerate nature of the cationic and anionic components keeps these components separate from one another during storage of the product but allows the cationic and anionic salts to be simultaneously released from the product upon mixing of the product with water and/or saliva to form a mixed aqueous solution such that the solution contains both calcium cations released from the calcium salt and orthophosphate anions released by the orthophosphate salt.

摘要翻译： 可用于再矿化地下牙齿损伤和/或矿化暴露的牙质小管的固体口服产品，例如口香糖，锭剂，食用食品等，其包含（A）由至少一个 水溶性或部分水溶性钙盐和第一惰性固体载体，和（B）由至少一种水溶性正磷酸盐和第二惰性固体载体组成的离散的阴离子附聚物组分。 阳离子和阴离子组分的聚集性质使这些组分在产物储存期间彼此分离，但是当产品与水和/或唾液混合时，允许阳离子和阴离子盐同时从产物中释放，以形成混合 水溶液使得溶液含有从钙盐释放的钙阳离子和由正磷酸盐释放的正磷酸盐阴离子。

公开(公告)号：US06440394B2

公开(公告)日：2002-08-27

申请号：US09893019

申请日：2001-06-26

申请人： Jordan Barth ,  Anthony E. Winston ,  Norman Usen

发明人： Jordan Barth ,  Anthony E. Winston ,  Norman Usen

IPC分类号： A61K916

CPC分类号： A61Q11/00 ,  A61K8/19 ,  A61K8/24 ,  A61K2800/88

摘要： A solid oral product, e.g., chewing gum, lozenge, an edible foodstuff, and the like, which is useful for remineralizing subsurface dental lesions and/or mineralizing exposed dentinal tubules, contains (A) a discrete cationic agglomerate component composed of at least one water-soluble or partially water-soluble calcium salt and a first inert solid carrier, and (B) a discrete anionic agglomerate component composed of at least one water-soluble orthophosphate salt and a second inert solid carrier. The agglomerate nature of the cationic and anionic components keeps these components separate from one another during storage of the product but allows the cationic and anionic salts to be simultaneously released from the product upon mixing of the product with water and/or saliva to form a mixed aqueous solution such that the solution contains both calcium cations released from the calcium salt and orthophosphate anions released by the orthophosphate salt.

公开(公告)号：US4814164A

公开(公告)日：1989-03-21

申请号：US837989

申请日：1986-03-10

申请人： Jordan Barth ,  Linda J. Vellekoop

发明人： Jordan Barth ,  Linda J. Vellekoop

IPC分类号： A61K8/00 ,  A61K8/20 ,  A61K8/27 ,  A61K8/34 ,  A61K8/35 ,  A61K8/36 ,  A61K8/365 ,  A61K8/73 ,  A61K9/00 ,  A61Q11/00 ,  A61K7/16 ,  A61K33/30

CPC分类号： A61Q15/00 ,  A61K8/0216 ,  A61K8/27 ,  A61K8/345 ,  A61K8/35 ,  A61K8/73 ,  A61K9/0056 ,  A61Q11/00

摘要： A non-cariogenic, long-acting, slow dissolving solid antitartar and mouth deodorant having improved taste, and a method of providing extended mouth odor reduction and control tartar formation comprising a zinc compound, which provides zinc, an ionone ketone terpene derivative and flavor, preferably mint, as the essential active ingredient in a sugar-free carrier.

摘要翻译： 具有改善味道的非致龋素，长效，缓慢溶解的固体antitartar和口腔除臭剂，以及提供延长口腔气味减少和控制牙垢形成的方法，包括提供锌，紫罗烯酮萜烯衍生物和风味剂的锌化合物， 优选薄荷，作为无糖载体中的必需活性成分。

公开(公告)号：US4663152A

公开(公告)日：1987-05-05

申请号：US413188

申请日：1982-08-30

申请人： Jordan Barth ,  James Norfleet

发明人： Jordan Barth ,  James Norfleet

IPC分类号： A61K8/04 ,  A61Q11/00 ,  A61K7/16

CPC分类号： A61Q11/00 ,  A61K8/0275 ,  A61K8/042 ,  A61K8/26 ,  A61K8/731 ,  A61K2800/262

摘要： Functional agglomerated speckles, for incorporation in dentifrices, include agglomerates of a water insoluble powdered functional material and water insoluble, ethanol soluble ethyl cellulose. Such speckles satisfactorily maintain their integrity and identity during processing of the dentifrice after addition of the speckles to the main dentifrice body but on storage, after packaging of the dentifrice in dispensing tubes, soften sufficiently so as to become essentially impalpable to one utilizing the dentifrice in brushing his teeth. Despite such softening the speckles continue to maintain their identity as speckles in the dentifrice. The speckles are especially useful in translucent or transparent gel dentifrices which contain components, such as flavoring and surface active agents, which may controllably soften the speckles on storage. Also described in the specification are methods for the manufacture of the mentioned speckles, dentifrices incorporating them, methods for manufacturing such dentifrices and such dentifrices packaged in end use dispensing containers.

摘要翻译： 用于掺入洁齿剂中的功能性聚集斑点包括水不溶性粉末状功能材料和水不溶性乙醇可溶性乙基纤维素的附聚物。 在将洁牙剂加入到主洁牙体之后，但在将洁齿剂包装在分配管中之后，在将洁牙剂加入到洁牙剂主体之后，在加工洁齿剂期间，这样的斑点令人满意地保持其完整性和身份，以充分软化，以便基本上不利于使用洁齿剂 刷牙 尽管如此软化，斑点继续保持其在洁牙剂中的斑点的身份。 斑点在透明或透明的凝胶洁齿剂中特别有用，其含有诸如调味剂和表面活性剂的组分，其可以可控地软化储存中的斑点。 在说明书中还描述了用于制造所述斑点的方法，包含它们的洁齿剂，制造这种洁齿剂的方法和包装在最终用途分配容器中的这种洁齿剂。

公开(公告)号：US4814163A

公开(公告)日：1989-03-21

申请号：US933968

申请日：1986-11-24

申请人： Jordan Barth

发明人： Jordan Barth

IPC分类号： A61K8/27 ,  A61K8/34 ,  A61K8/35 ,  A61K8/73 ,  A61K9/00 ,  A61Q11/00 ,  A61K7/16 ,  A61K33/30

CPC分类号： A61Q15/00 ,  A61K8/0216 ,  A61K8/27 ,  A61K8/345 ,  A61K8/35 ,  A61K8/73 ,  A61K9/0056 ,  A61Q11/00

摘要： A non-cariogenic, long-acting, slow dissolving solid antitartar mouth deodorant having improved taste, and a method of providing extended mouth odor reduction and control of tartar formation comprising a zinc compound which provides zinc, an ionone ketone terpene derivative and a mint flavor, as the essential active ingredients with a gluconate salt and an acidic pH to aid in zinc solubilization, in a sugar-free carrier.

摘要翻译： 具有改善味道的非致龋剂，长效慢溶解固体antitartar口腔除臭剂和提供口腔气味减少和控制牙垢形成的方法，包括提供锌的锌化合物，紫罗酮酮萜烯衍生物和薄荷味 ，作为具有葡萄糖酸盐和酸性pH的基本活性成分，以帮助锌溶解，在无糖载体中。

公开(公告)号：US4376763A

公开(公告)日：1983-03-15

申请号：US307273

申请日：1981-09-30

申请人： Jordan Barth ,  James Norfleet

发明人： Jordan Barth ,  James Norfleet

IPC分类号： A61K8/04 ,  A61Q11/00 ,  A61K7/16

CPC分类号： A61Q11/00 ,  A61K8/0275 ,  A61K8/042 ,  A61K8/26 ,  A61K8/731 ,  A61K2800/262

摘要： Functional agglomerated speckles, for incorporation in dentifrices, include agglomerates of a water insoluble powdered functional material and water insoluble, ethanol soluble ethyl cellulose. Such speckles satisfactorily maintain their integrity and identity during processing of the dentifrice after addition of the speckles to the main dentifrice body but on storage, after packaging of the dentifrice in dispensing tubes, soften sufficiently so as to become essentially impalpable to one utilizing the dentifrice in brushing his teeth. Despite such softening the speckles continue to maintain their identity as speckles in the dentifrice. The speckles are especially useful in translucent or transparent gel dentifrices which contain components, such as flavoring and surface active agents, which may controllably soften the speckles on storage. Also described in the specification are methods for the manufacture of the mentioned speckles, dentifrices incorporating them, methods for manufacturing such dentifrices and such dentifrices packaged in end use dispensing containers.

公开(公告)号：US4444570A

公开(公告)日：1984-04-24

申请号：US413187

申请日：1982-08-30

申请人： Jordan Barth ,  James Norfleet

发明人： Jordan Barth ,  James Norfleet

IPC分类号： A61K8/04 ,  A61Q11/00 ,  C09K3/14

CPC分类号： A61Q11/00 ,  A61K8/0275 ,  A61K8/042 ,  A61K8/19 ,  A61K8/731 ,  A61K2800/262

摘要： Functional agglomerated speckles, for incorporation in dentifrices, include agglomerates of a water insoluble powdered functional material and water insoluble, ethanol soluble ethyl cellulose. Such speckles satisfactorily maintain their integrity and identity during processing of the dentifrice after addition of the speckles to the main dentifrice body but on storage, after packaging of the dentifrice in dispensing tubes, soften sufficiently so as to become essentially impalpable to one utilizing the dentifrice in brushing his teeth. Despite such softening the speckles continue to maintain their identity as speckles in the dentifrice. The speckles are especially useful in translucent or transparent gel dentifrices which contain components, such as flavoring and surface active agents, which may controllably soften the speckles on storage. Also described in the specification are methods for the manufacture of the mentioned speckles, dentifrices incorporating them, methods for manufacturing such dentifrices and such dentifrices packaged in end use dispensing containers.

摘要翻译： 用于掺入洁齿剂中的功能性聚集斑点包括水不溶性粉末状功能材料和水不溶性乙醇可溶性乙基纤维素的附聚物。 在将洁牙剂加入到主洁牙体之后，但在将洁齿剂包装在分配管中之后，在将洁牙剂加入到洁牙剂主体之后，在加工洁齿剂期间，这样的斑点令人满意地保持其完整性和身份，以充分软化，以便基本上不利于使用洁齿剂 刷牙 尽管如此软化，斑点继续保持其在洁牙剂中的斑点的身份。 斑点在透明或透明的凝胶洁齿剂中特别有用，其含有诸如调味剂和表面活性剂的组分，其可以可控地软化储存中的斑点。 在说明书中还描述了用于制造所述斑点的方法，包含它们的洁齿剂，制造这种洁齿剂的方法和包装在最终用途分配容器中的这种洁齿剂。

公开(公告)号：US4765984A

公开(公告)日：1988-08-23

申请号：US939892

申请日：1986-12-16

申请人： Linda J. Vellekoop ,  Jordan Barth

发明人： Linda J. Vellekoop ,  Jordan Barth

IPC分类号： A61K8/24 ,  A61K8/26 ,  A61K8/73 ,  A61K8/92 ,  A61Q11/00 ,  A61K9/68

CPC分类号： A61K8/733 ,  A61K8/24 ,  A61K8/26 ,  A61K8/73 ,  A61K8/922 ,  A61Q11/00 ,  A61K2800/594

摘要： A single unit dose chewable oral product stabilized against syneresis comprising an alginate gelling agent, cross-linked with a calcium ion, flavor and a liquid vehicle containing water, humectant and a vegetable oil additive to reduce syneresis.

摘要翻译： 针对脱水收缩稳定的单一单位剂量可咀嚼口服产品，其包含藻酸盐胶凝剂，与钙离子交联，风味剂和含有水的液体载体，湿润剂和植物油添加剂以减少脱水收缩。

公开(公告)号：US4132770A

公开(公告)日：1979-01-02

申请号：US857478

申请日：1977-12-05

申请人： Jordan Barth

发明人： Jordan Barth

IPC分类号： A61K8/19 ,  A61K8/86 ,  A61K8/90 ,  A61K8/92 ,  A61Q11/00 ,  A61K7/16

CPC分类号： A61K8/90 ,  A61K8/19 ,  A61K8/86 ,  A61K8/922 ,  A61Q11/00 ,  A61K2800/43

摘要： There is disclosed an aqueous oral product including sodium bicarbonate in solution, a flavor oil where desired, and at least one emulsifying agent for said flavor oil; and a dye if color is required; there may optionally be included a cosmetic alcohol, a humectant and sweetening agents. The product is especially suitable as a mouthwash and rinse.

摘要翻译： 公开了一种水溶性口服产品，包括溶液中的碳酸氢钠，需要的风味油和至少一种用于所述调味油的乳化剂; 如果需要颜色，则为染料; 可以任选地包含化妆品醇，保湿剂和甜味剂。 该产品特别适合作为漱口水和冲洗液。